Vance Garrison Fowler, MD

Professor of Medicine
Florence McAlister Distinguished Professor of Medicine
Professor in Molecular Genetics and Microbiology
Member in the Duke Clinical Research Institute
Campus mail Duke Box 102359, Hanes House, Trent Drive, Durham, NC 27710
Phone (919) 613-5678
Email address fowle003@mc.duke.edu

Determinants of Outcome in Patients with Staphylococcus aureus Bacteremia
Antibacterial Resistance
Pathogenesis of Bacterial Infections
Tropical medicine/International Health

Education and Training

  • Fellow, Infectious Diseases, Medicine, Duke University, 1996 - 1999
  • Medical Resident, Medicine, Duke University, 1993 - 1996
  • M.H.S., Duke University, 1999
  • M.D., University of North Carolina - Chapel Hill, 1993

Publications

Chan, Liana C., Maura Rossetti, Lloyd S. Miller, Scott G. Filler, Colin W. Johnson, Hong K. Lee, Huiyuan Wang, et al. “Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory.” Proc Natl Acad Sci U S A 115, no. 47 (November 20, 2018): E11111–19. https://doi.org/10.1073/pnas.1808353115.

PMID
30297395
Full Text

Satlin, Michael J., Kalyan D. Chavda, Thomas M. Baker, Liang Chen, Elena Shashkina, Rosemary Soave, Catherine B. Small, et al. “Colonization With Levofloxacin-resistant Extended-spectrum β-Lactamase-producing Enterobacteriaceae and Risk of Bacteremia in Hematopoietic Stem Cell Transplant Recipients.” Clin Infect Dis 67, no. 11 (November 13, 2018): 1720–28. https://doi.org/10.1093/cid/ciy363.

PMID
29701766
Full Text

Duin, David van, Peidi Gu, Jane Dong, Melanie Paff, Rebekka M. Arias, Beth Evans, Yunsong Yu, et al. “China-United States Research Collaborations in Antimicrobial Resistance.” Clin Infect Dis 67, no. suppl_2 (November 13, 2018): S142–45. https://doi.org/10.1093/cid/ciy694.

PMID
30423056
Full Text

DebRoy, Sruti, Xiqi Li, Awdhesh Kalia, Jessica Galloway-Pena, Brittany J. Shah, Vance G. Fowler, Anthony R. Flores, and Samuel A. Shelburne. “Identification of a chimeric emm gene and novel emm pattern in currently circulating strains of emm4 Group A Streptococcus.” Microb Genom 4, no. 11 (November 2018). https://doi.org/10.1099/mgen.0.000235.

PMID
30412460
Full Text

Scott, William K., Felix Mba Medie, Felicia Ruffin, Batu K. Sharma-Kuinkel, Derek D. Cyr, Shengru Guo, Derek M. Dykxhoorn, et al. “Human genetic variation in GLS2 is associated with development of complicated Staphylococcus aureus bacteremia.” Plos Genet 14, no. 10 (October 2018): e1007667. https://doi.org/10.1371/journal.pgen.1007667.

PMID
30289878
Full Text

Holland, Thomas L., Issam Raad, Helen W. Boucher, Deverick J. Anderson, Sara E. Cosgrove, P Suzanne Aycock, John W. Baddley, et al. “Effect of Algorithm-Based Therapy vs Usual Care on Clinical Success and Serious Adverse Events in Patients with Staphylococcal Bacteremia: A Randomized Clinical Trial.” Jama 320, no. 12 (September 25, 2018): 1249–58. https://doi.org/10.1001/jama.2018.13155.

PMID
30264119
Full Text

Maskarinec, Stacey A., Zehra Parlak, Qing Tu, Vrad Levering, Stefan Zauscher, Gabriel P. López, Vance G. Fowler, and John R. Perfect. “On-demand release of Candida albicans biofilms from urinary catheters by mechanical surface deformation.” Biofouling 34, no. 6 (July 2018): 595–604. https://doi.org/10.1080/08927014.2018.1474461.

PMID
29897277
Full Text

Ojewole, Adegoke A., Jonathan D. Jou, Vance G. Fowler, and Bruce R. Donald. “BBK* (Branch and Bound Over K*): A Provable and Efficient Ensemble-Based Protein Design Algorithm to Optimize Stability and Binding Affinity Over Large Sequence Spaces.” J Comput Biol 25, no. 7 (July 2018): 726–39. https://doi.org/10.1089/cmb.2017.0267.

PMID
29641249
Full Text

Jaslow, Sarah L., Kyle D. Gibbs, W Florian Fricke, Liuyang Wang, Kelly J. Pittman, Mark K. Mammel, Joshua T. Thaden, et al. “Salmonella Activation of STAT3 Signaling by SarA Effector Promotes Intracellular Replication and Production of IL-10.” Cell Rep 23, no. 12 (June 19, 2018): 3525–36. https://doi.org/10.1016/j.celrep.2018.05.072.

PMID
29924996
Full Text

Huskins, W Charles, Vance G. Fowler, and Scott Evans. “Adaptive Designs for Clinical Trials: Application to Healthcare Epidemiology Research.” Clin Infect Dis 66, no. 7 (March 19, 2018): 1140–46. https://doi.org/10.1093/cid/cix907.

PMID
29121202
Full Text

Pages