Victor J. Dzau, MD

Professor of Medicine
James B. Duke Professor of Medicine
Professor of Pathology
Campus mail Victor J. Dzau Laboratory GSRBII # Room 4015, Duke University, Durham, NC 27710
Phone (919) 668-5448
Email address victor.dzau@duke.edu

Education and Training

  • Fellow in Cardiology, Medicine, Massachusetts General Hospital, 1979 - 1980
  • Chief Resident Physician, Children's Hospital Boston, 1978 - 1979
  • Fellow in Cardiology, Medicine, Massachusetts General Hospital, 1976 - 1978
  • Postdoctoral Research Fellow, Physiology, Harvard University, 1976 - 1978
  • Senior Assistant Resident, Children's Hospital Boston, 1975 - 1976
  • Clincal Fellow, Medicine, Harvard University, 1974 - 1976
  • Assistant Resident, Children's Hospital Boston, 1974 - 1975
  • Resident in Pathology, Pathology, Children's Hospital Boston, 1973 - 1974
  • Intern in Medicine, Medicine, Cornell University, 1972 - 1973
  • M.D., McGill University (Canada), 1972

Publications

Liu, X, Simpson, JA, Brunt, KR, Ward, CA, Hall, SRR, Kinobe, RT, Barrette, V, Tse, MY, Pang, SC, Pachori, AS, Dzau, VJ, Ogunyankin, KO, and Melo, LG. "Preemptive heme oxygenase-1 gene delivery reveals reduced mortality and preservation of left ventricular function 1 yr after acute myocardial infarction." Am J Physiol Heart Circ Physiol 293, no. 1 (July 2007): H48-H59.

PMID
17322421
Full Text

Matsushita, K, Zhang, Z, Pratt, RE, and Dzau, VJ. "Molecular mechanism of juxtaglomerular cell hyperplasia: a unifying hypothesis." J Am Soc Hypertens 1, no. 3 (May 2007): 164-168.

PMID
20409848
Full Text

Mirotsou, M, Zhang, Z, Deb, A, Zhang, L, Gnecchi, M, Noiseux, N, Mu, H, Pachori, A, and Dzau, V. "Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair." Proc Natl Acad Sci U S A 104, no. 5 (January 30, 2007): 1643-1648.

PMID
17251350
Full Text

Dzau, VJ, Antman, EM, Black, HR, Hayes, DL, Manson, JE, Plutzky, J, Popma, JJ, and Stevenson, W. "The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part I: Pathophysiology and clinical trial evidence (risk factors through stable coronary artery disease)." Circulation 114, no. 25 (December 19, 2006): 2850-2870. (Review)

PMID
17179034
Full Text

Dzau, VJ, Antman, EM, Black, HR, Hayes, DL, Manson, JE, Plutzky, J, Popma, JJ, and Stevenson, W. "The cardiovascular disease continuum validated: clinical evidence of improved patient outcomes: part II: Clinical trial evidence (acute coronary syndromes through renal disease) and future directions." Circulation 114, no. 25 (December 19, 2006): 2871-2891. (Review)

PMID
17179035
Full Text

Matsushita, K, Wu, Y, Okamoto, Y, Pratt, RE, and Dzau, VJ. "Local renin angiotensin expression regulates human mesenchymal stem cell differentiation to adipocytes." Hypertension 48, no. 6 (December 2006): 1095-1102.

PMID
17060512
Full Text

Noiseux, N, Gnecchi, M, Lopez-Ilasaca, M, Zhang, L, Solomon, SD, Deb, A, Dzau, VJ, and Pratt, RE. "Mesenchymal stem cells overexpressing Akt dramatically repair infarcted myocardium and improve cardiac function despite infrequent cellular fusion or differentiation." Mol Ther 14, no. 6 (December 2006): 840-850.

PMID
16965940
Full Text

Mirotsou, M, Dzau, VJ, Pratt, RE, and Weinberg, EO. "Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy." Physiol Genomics 27, no. 1 (October 3, 2006): 86-94.

PMID
16835353
Full Text

Wu, Y, Ip, JE, Huang, J, Zhang, L, Matsushita, K, Liew, C-C, Pratt, RE, and Dzau, VJ. "Essential role of ICAM-1/CD18 in mediating EPC recruitment, angiogenesis, and repair to the infarcted myocardium." Circ Res 99, no. 3 (August 4, 2006): 315-322.

PMID
16825578
Full Text

Gnecchi, M, He, H, Noiseux, N, Liang, OD, Zhang, L, Morello, F, Mu, H, Melo, LG, Pratt, RE, Ingwall, JS, and Dzau, VJ. "Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement." FASEB J 20, no. 6 (April 2006): 661-669.

PMID
16581974
Full Text

Pages