Virginia Byers Kraus, MD, PhD

Professor of Medicine
Professor of Pathology
Professor in Orthopaedic Surgery
Member of Duke Molecular Physiology Institute
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke St, Carmichael Building Room 15-205, Durham, NC 27701-2047
Phone (919) 681-6652
Email address kraus004@duke.edu

My special area of expertise is as a clinician scientist investigating osteoarthritis. Osteoarthritis is the most common form of joint disease in man and its incidence increases with age. It is a problem of increasing concern to the medical community due to the increasing longevity of the population. Trained as a molecular biologist and a Rheumatologist, I endeavor to study this disease from bedside to bench.

The work in this laboratory focuses on osteoarthritis and deals with the mechanisms of joint damage, and the discovery, validation and qualification of novel biochemical and genetic biomarkers for minimally invasive means of diagnosing disease, for predicting progression of disease, and for monitoring disease progression and response to therapy.

Education and Training

  • Fellow in Rheumatology, Medicine, Duke University, 1986 - 1989
  • Medical Resident, Medicine, Duke University, 1983 - 1986
  • Ph.D., Duke University, 1993
  • M.D., Duke University, 1982

Publications

Jordan, JM, Kraus, VB, and Hochberg, MC. "Genetics of osteoarthritis." Curr Rheumatol Rep 6, no. 1 (February 2004): 7-13. (Review)

PMID
14713397
Scholars@Duke

Eckstein, F, Buck, RJ, Charles, HC, Hudelmaier, M, Wirth, W, Kraus, VB, and Evelhoch, JL. "Improved precision of quantitative cartilage measurements with magnetic resonance imaging at 3 T." 2004.

Scholars@Duke

Kraus, VB. "Using epidemiologic studies to identify surrogates for radiographic outcome." 2004.

Scholars@Duke

Dragomir, AD, Jordan, JM, Kraus, VB, Luta, G, Renner, JB, and Poole, AR. "Altered levels of serum cartilage markers in postmenopausal African-American and caucasian women on current hormone replacement therapy." 2004.

Scholars@Duke

Kraus, VB, Stabler, T, Le, ET, Saltarelli, M, and Allen, NB. "Urinary type II collagen neoepitope as an outcome measure for relapsing polychondritis." Arthritis Rheum 48, no. 10 (October 2003): 2942-2948.

PMID
14558101
Full Text

Dragomir, AD, Kraus, VB, Luta, G, Stabler, T, Renner, JB, Helmick, CG, Hochberg, MC, and Jordan, JM. "Lower levels of 2 putative biomarkers of osteoarthritis (OA) in postmenopausal African American and Caucasian women on current hormone replacement therapy." September 2003.

Scholars@Duke

Jordan, JM, Kraus, VB, Renner, JB, Luta, G, Dragomir, AD, Stabler, T, Vilim, V, Hochberg, MC, and Helmick, CG. "Associations between medical co-morbidities and putative biomarkers of osteoarthritis (OA)." September 2003.

Scholars@Duke

Stabler, TV, and Kraus, VB. "Ascorbic acid accumulates in cartilage in vivo." Clin Chim Acta 334, no. 1-2 (August 2003): 157-162.

PMID
12867287
Scholars@Duke

Lamers, R-JAN, DeGroot, J, Spies-Faber, EJ, Jellema, RH, Kraus, VB, Verzijl, N, TeKoppele, JM, Spijksma, GK, Vogels, JTWE, van der Greef, J, and van Nesselrooij, JHJ. "Identification of disease- and nutrient-related metabolic fingerprints in osteoarthritic Guinea pigs." The Journal of Nutrition 133, no. 6 (June 2003): 1776-1780.

PMID
12771316
Full Text

Kraus, VB. "Cyclooxygenase-2 inhibitors and nonsteroidal anti-inflammatory drugs in the management of arthritis." Foot Ankle Clin 8, no. 2 (June 2003): 187-vii. (Review)

PMID
12911235
Scholars@Duke

Pages