Dr. Diamantidis shares her AKI research

Friday, September 8, 2017

We are proud to show off some of the work Dr. Clarissa Diamantidis has been leading, including her work as principal investigator on a research study on Acute Kidney Injury (AKI), called Change AKI. 

Change AKI is a pilot study evaluating the feasibility and acceptability of a patient-centered mobile health (mHealth) educational program promoting AKI awareness and reduction of contributory behaviors among hospitalized AKI survivors at Duke Medical Center. The long-term goal is to develop patient-centered educational materials to reduce AKI recurrence. The researchers hypothesize that a tailored educational curriculum will improve patient awareness of potential hazards and reduce AKI recurrence among hospital-based AKI survivors.

Project summary:

Name of Study: Understanding the role of patient behavior change in improving AKI outcomes 

Study Acronym: Change AKI Study

Principal Investigator:  Clarissa Jonas Diamantidis, MD, MHS

Funding Agency: Doris Duke Charitable Foundation- Fund to Retain Clinical Scientists at Duke

Project Staff:

Study Coordinators: Jennie Riley, MS and Nikita Shah
Programmer: Avi Alkon
Collaborators: Jennifer St. Clair Russell, PhD, MSEd, MCHES and Joseph Lunyera, MBChB

This study consist of three parts:

1.      Baseline surveys and Questionnaires: During baseline, all patients answer questions surrounding the following subjects: (1) Demographics, (2) e-Literacy (designed to assess patient’s knowledge of technology), (3) REALM, (4) Patient Safety Behaviors, (5) AKI Self-Awareness and (6) AKI Knowledge.

2.      AKI Educational Intervention: Those randomized to the intervention arm are then given an iPad to review the Change AKI program. The educational intervention includes clinical vignettes, educational programming, and pre- and post-test knowledge assessments via RedCap surrounding 2 themes related to patient safety in acute kidney injury: (1) use of non-steroidal anti-inflammatory drugs (NSAIDs) and (2) sick-day protocol (e.g. the avoidance of certain medicines when volume deplete to prevent AKI).   

3.      1-Month Follow-Up: Study staff will follow-up with patients via phone one month after discharge, and cover the following subjects: (1) Patient Safety Behaviors, (2) AKI Self-Awareness, (3) AKI Knowledge and (4) Pain Scale.

Study Progress: The Change AKI Study is actively recruiting patients.