New funding awards - August 2020

Monday, September 21, 2020

Sponsored Research

Sreekanth Vemulapalli of Cardiology has received a sub-award (5K23-AG055667-02) through the American College of Cardiology Foundation for a project entitled "Palliative Care for High-Risk TAVR Patients: The Impact of Multimorbidity." Total funding will be $31,442.

Matthew Hirschey of Endocrinology has received an award (3R01-DK115568-03S1) from the National Institutes of Health for a project entitled "Post-Translational and Epigenetic Control of Branched-Chain Amino Acid Metabolism." Total funding will be $122,560.

Anna Mae Diehl of Gastroenterology has received a sub-award (1R01-ES031596-01) through the North Carolina State University for a project entitled "The Imprinted Gene Network in the programming of non-alcoholic fatty liver disease by early life cadmium exposure." Total funding will be $7,668.

Ebony Boulware of General Internal Medicine has received an award from the Dialysis Clinic Inc. for a project entitled "Morbidity and Mortality during the Long Interdialytic Interval." Total funding will be $89,125.

Ranee Chatterjee Montgomery of General Internal Medicine has received a sub-award (1U19-AG065188-01-01) through the DCRI-Duke-Site for a project entitled "PRagmatic EValuation of evENTs And Benefits of Lipid-lowering in oldEr adults (PREVENTABLE)." Total funding will be $1.

Kenneth Lyles of Geriatrics has received a sub-award (R01-AG059417-02) through the Parkinson Foundation for a project entitled "Telemedicine agreement for TOPAZ Clinical Trial." Total funding will be $1.

Daniel Parker of Geriatrics has received an award (1R03-AG067897-01) from the National Institutes of Health for a project entitled "Healthy Skeletal Muscle, Healthy Brain: Are Kynurenine Metabolites the Link?." Total funding will be $322,000.

Grace Lee of Hematology has received an award (1R03-HL144897-01A1) from the National Institutes of Health for a project entitled "Variability in neutrophil activation." Total funding will be $161,000.

Thomas Ortel of Hematology has received a sub-award (6-NU38OT000280-02-04) through the Association of University Centers on Disabilities for a project entitled "Improving venous thromboembolism surveillance with natural language processing." Total funding will be $240,000.

Marilyn Telen of Hematology has received a sub-award (4UH-3HL143192-02) through the University of Pittsburgh for a project entitled "Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE)." Total funding will be $39,582.

James White of Hematology has received an award (5K01-AG056664-4S1) from the National Institutes of Health for a project entitled "The AMPK/ULK1/p27Kip1 axis regulates autophagy and cell survival in aged satellite cells." Total funding will be $45,956.

Chris Woods of Infectious Diseases has received an award from the Institute for Medical Research, Inc. for a project entitled "IMR PSA: Deb Murray (CLOVER)." Total funding will be $48,927.

Carey Anders of Medical Oncology has received an award from the Suzhou Zanrong Pharma Limited for a project entitled "A Phase 1 Clinical Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ZN-A-1041 Enteric Capsules as a Single Agent or in Combination with Capecitabine Tablets in Patients with HER2-Positive Advanced Solid Tumors." Total funding will be $1,021,696.

Jeremy Force of Medical Oncology has received an award from the Metavivor for a project entitled "Discovery and validation of putative oncogenic ROS1 alterations in metastatic breast cancer." Total funding will be $50,000.

Michael P. Plebanek (Mentor: Brent Hanks) of Medical Oncology has received an award (1F32-CA247067-01A1) from the National Institutes of Health for a project entitled "Tumor-derived Exosome Induction of Dendritic Cell Tolerization." Total funding will be $197,682.

Arif Kamal of Medical Oncology has received a sub-award () through the American Academy of Hospice and Palliative Medicine for a project entitled "Development of a National Palliative Care Quality Collaborative." Total funding will be $302,892.

Kevin Oeffinger of Medical Oncology has received an award (5R01-CA134722-08S1) from the National Institutes of Health for a project entitled "EMPOWER Study: Promoting BC Screening in Women Who Survived Childhood Cancer Administrative Supplement." Total funding will be $149,999.

Opeyemi Olabisi of Nephrology has received an award from the Robert Wood Johnson Foundation for a project entitled "Unmasking the Molecular Mechanism of ApoL1 Nephropathy." Total funding will be $20,691.

Christina Barkauskas of Pulmonary has received a sub-award (1R01-ES031253-01) through the West Virginia University for a project entitled "Impact of particle and ozone inhalation co-exposure on alveolar epithelial regeneration." Total funding will be $21,434.

Loretta Que of Pulmonary has received an award (1R01-HL153641-01) from the National Institutes of Health for a project entitled "Oxidative Stress and Regional Airway Remodeling and Fibrosis in Obese Asthma." Total funding will be $2,989,006.

Brian Andonian of Rheumatology has received an award (1R03-AG067949-01) from the National Institutes of Health for a project entitled "Accelerated Metabolic Aging in Rheumatoid Arthritis Immune cells and Skeletal Muscle: A Pilot Study." Total funding will be $322,000.

Industry-sponsored Clinical Trials

Renato Lopes of Cardiology has received an award from Eli Lilly and Company for a project entitled "H9X-MC-GBGO." Total funding will be $87,634.

Jonathan Piccini of Cardiology has received an award from Medtronic, Inc. for a project entitled "Accelerometer Sensing for Micra AV." Total funding will be $67,672.

Manal Abdelmalek of Gastroenterology has received an award from SC Liver Research Consortium, LLC for a project entitled "TERN101-201 - A Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Phase 2a Clinical Trial to Evaluate the Safety, Tolerability, Efficacy, and Pharmacokinetics of Orally Administered TERN-101 Tablets in Adult Patients." Total funding will be $177,667.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Amgen, Inc. for a project entitled "A Phase 1 First-in-human Study Evaluating the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of AMG 427 in Subjects with Relapsed/Refractory Acute Myeloid Leukemia." Total funding will be $1,589,856.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Novartis Phase II MBG453 in combination with Venetoclax and Azacitidine in AML." Total funding will be $509,051.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Agios Pharmaceuticals, Inc. for a project entitled "Agios MDS and Organ Impairment study." Total funding will be $210,292.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from ADC Therapeutics Sarl for a project entitled "An Open-label Pilot Multicenter Study to Evaluate the Safety and Efficacy of ADCT-301 in Patients with Relapsed or Refractory CD25-positive Acute Myeloid Leukemia, myelodysplastic syndrome, or myeloproliferative neoplasms." Total funding will be $144,750.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from Mustang Bio for a project entitled "A Long-term Follow-up Study in Patients Previously Treated with Mustang Bio, Inc. CAR-T Cell Investigational Products." Total funding will be $76,561.

Andrea Sitlinger of Hematologic Malignancies and Cellular Therapy has received an award from MEI Pharma, Inc. for a project entitled "A Multicenter, Open-Label, Single-Arm, Phase 2 Study of ME-401 in Subjects with Follicular Lymphoma After Failure of Two or More Prior Systemic Therapies." Total funding will be $161,016.

Nirmish Shah of Hematology has received an award from Global Blood Therapeutics, Inc. for a project entitled "GBT440-039 A Phase 4, Multicenter, Open-label Study to Evaluate the Treatment Effect of Voxelotor on Physical Activity in Adolescents and Adults with Sickle Cell Disease." Total funding will be $77,000.

Scott Antonia of Medical Oncology has received an award from Nektar Therapeutics for a project entitled "Nektar PROPEL." Total funding will be $201,895.

Jeffrey Crawford of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "A Phase 1b, 12-Week, Open-Label Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Following Repeated Subcutaneous Administrations of PF-06946860 In Patients with Non-Small Cell Lung Cancer and Cachexia." Total funding will be $125,592.

Andrew Nixon of Medical Oncology has received an award from Alliance for Clinical Trials in Oncology Foundation for a project entitled "IL-6 in PDIGREE (AO31704)." Total funding will be $90,288.

Andrew Nixon of Medical Oncology has received an award from Promega for a project entitled "MSI in mCRC." Total funding will be $14,410.

Richard Riedel of Medical Oncology has received an award from Epizyme, Inc for a project entitled ""A Phase 3, Global, Randomized, Double-Blind Trial of Tazemetostat in Combination with Doxorubicin as Frontline Therapy for Advanced Epithelioid Sarcoma"." Total funding will be $128,767.

Tian Zhang of Medical Oncology has received an award from NeoImmuneTech, Inc. for a project entitled "NeoImmune NMTNT110." Total funding will be $209,177.