New funding awards - December 2019

Tuesday, January 21, 2020

Sponsored Research

Eric Eisenstein of Cardiology has received a sub-award (HHSF223201510105C) through the University of Arkansas for Medical Sciences for a project entitled "The Data FITS Study of EHR-to-EDC eSource Data Collection." Total funding will be $24,207.

Adrian Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "PCORnet Phase II Rapid Research TO#13 Mod 4." Total funding will be $133,543.

Christopher Holley of Cardiology has received an award (1R01-GM135383-01) from the National Institutes of Health for a project entitled "SnoRNA-guided modifications of mRNA." Total funding will be $1,288,000.

Francis Miller of Cardiology has received a sub-award () through the North Carolina State University for a project entitled "Improving the Performance and Design of Potentiometric Biosensors for the Detection of Extracellular Histones in Blood with Deep Learning." Total funding will be $88,355.

Jonathan Piccini of Cardiology has received an award from the American Heart Association for a project entitled "Get With The Guidelines (GWTG) Task Order #25." Total funding will be $74,610.

Jonathan Stiber of Cardiology has received an award (1R01-HL147157-01A1) from the National Institutes of Health for a project entitled "Anti-Atherogenic Mechanisms of Drebrin." Total funding will be $2,093,000.

Leigh Boulware of General Internal Medicine has received an award from the National Institutes of Health for a project entitled "Bruce Burnett IPA." Total funding will be $98,043.

Mitchell Horwitz of Hematologic Malignancies and Cellular Therapy has received a sub-award () through the National Marrow Donor Program for a project entitled "BMT CTN 1705 ¿ HR aGVHD AAT." Total funding will be $170,418.

Vance Fowler of Infectious Diseases has received an award (2UM-AI104681-08) from the National Institutes of Health for a project entitled "Antibacterial Resistance Leadership Group (ARLG)." Total funding will be $102,495,714.

Vance Fowler of Infectious Diseases has received an award from the Universitair Medisch Centrum Utrecht for a project entitled "Vaccine Trial_LOI." Total funding will be $2,015,550.

Nathan Thielman of Infectious Diseases has received a sub-award (3D43-TW009337-09) through the Vanderbilt University Medical Center for a project entitled "Formative Research to Assess Needs, Examine Outcomes, and Inform Future Training Interventions for Community-Based HIV Services in Moshi, Tanzania." Total funding will be $86,195.

Nathan Thielman of Infectious Diseases has received a sub-award (3D43-TW009337-09) through the Vanderbilt University Medical Center for a project entitled "Sepsis in sub-Saharan Africa: a prospective observational study of clinical management, outcomes, and barriers to care in northern Tanzania." Total funding will be $26,786.

David Bartlett of Medical Oncology has received an award from the American Society of Hematology for a project entitled "Exercise training to promote improved immune resilience in adults with chronic lymphocytic leukemia - a randomized control trial." Total funding will be $149,603.

Arif Kamal of Medical Oncology has received an award from the Blue Cross and Blue Shield of NC Foundation for a project entitled "Symmetry Development and Implementation." Total funding will be $477,100.

Andrew Nixon of Medical Oncology has received a sub-award (3U10-CA180868-06S1R) through the NRG Oncology for a project entitled "Angiome Profiling of GY012." Total funding will be $258,826.

Steven Patierno of Medical Oncology has received an award (5P20-CA202925-04S2) from the National Institutes of Health for a project entitled "Investigation of the role of X-Linked Inhibitor of Apoptosis Protein in African American IBC-derived Organoid Models." Total funding will be $68,947.

John Strickler of Medical Oncology has received a sub-award () through the Academic and Community Cancer Research United for a project entitled "PULSE: A Randomized, Phase II Open Label Study of PanitUmumab RechaLlenge Versus Standard Therapy after Progression on Anti-EGFR Therapy in Patients with Metastatic and/or Unresectable RAS Wild-Type Colorectal Cancer." Total funding will be $1,706,245.

John Strickler of Medical Oncology has received a sub-award () through the Academic and Community Cancer Research United for a project entitled "COLOMATE: COlorectal Cancer Liquid BiOpsy Screening Protocol for Molecularly Assigned ThErapy." Total funding will be $3,500.

Linda Sutton of Medical Oncology has received an award from the V Foundation for Cancer Research for a project entitled "Advancing Cancer Care in the Rural Southeast: Delivering Novel Therapies In Our Community Cancer Centers." Total funding will be $80,000.

Shintaro Ide (Mentor: Myles Wolf) of Nephrology has received an award from the American Heart Association for a project entitled "Targeting anti-ferroptotic pathways to prevent the AKI-to-CKD transition." Total funding will be $72,950.

Scott Palmer of Pulmonary has received a sub-award (U01-HL145435-01) through the University of Pennsylvania for a project entitled "Long Term Follow up of the Lung Transplant Outcomes Group Cohort." Total funding will be $209,202.

Industry-sponsored Clinical Trials

Melissa Daubert of Cardiology has received an award from ContraFect Corporation for a project entitled "CF-301 Phase III." Total funding will be $697,526.

Terry Fortin of Cardiology has received an award from Janssen Research & Development, LLC for a project entitled "AC-065B302 Select: Radomized double blind placebo controlled parallel group group sequential adaptive Phase 3 study with open label extention period to assess efficacy and safety of Selexipag." Total funding will be $189,426.

Michel Khouri of Cardiology has received an award from Pfizer, Inc. for a project entitled ""Use of electrophysiologic variables from cardiac implantable electronic devices to understand and diagnose ATTR cardiac amyloidosis"." Total funding will be $75,000.

Kishan Parikh of Cardiology has received an award from Cytokinetics, Inc. for a project entitled "Multicenter Exercise Tolerance Evaluation of Omecamtiv Mecarbil Related to Increased Contractility in Heart Failure." Total funding will be $101,650.

Manal Abdelmalek of Gastroenterology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "A Phase 2, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Pharmacodynamic Effects of MEDI0382 in Obese Subjects with Non-alcoholic Fatty Liver Disease (NAFLD)/Non-alcoholic Steatohepatitis (NASH)." Total funding will be $517,469.

Andrew Muir of Gastroenterology has received an award from CymaBay Therapeutics for a project entitled "CymaBay Phase 2 PSC CB8025-21845." Total funding will be $11,000.

Harvey Jay Cohen of Geriatrics has received a sub-award (1R03-AG064382-01) through Geisinger Health System for a project entitled "Geriatric Conditions and Treatment Burden in Older Adults with Superficial Bladder Cancer." Total funding will be $11,373.

Ara Metjian of Hematology has received an award from Baxalta, Inc. for a project entitled "Obizur EU PASS. Prospective and retrospective, non-interventional study to evaluate the safety and effectiveness of Obizur in real-life practice.." Total funding will be $34,694.

Gregory Gray of Infectious Diseases has received a sub-award (N6264518D5058-N62645) through Vysnova Partners, Inc. for a project entitled "Southeast Asia Biosurveillance & Epidemiology Research (Federal Contract)." Total funding will be $85,142.

John Perfect of Infectious Diseases has received an award from Appili Therapeutics for a project entitled "T-2307 Efficacy in Rabbit Cryptococcal Meningitis." Total funding will be $87,323.

Andrew Armstrong of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase 3, Randomized, Double-blind Study of Pembrolizumab (MK-3475) Plus Docetaxel Plus Prednisone versus Placebo Plus Docetaxel Plus Prednisone in Participants with Chemotherapy-naive Metastatic Castration-Resistant Prostate Cancer." Total funding will be $1,102,630.

Jennifer Choe of Medical Oncology has received an award from Compass Therapeutics for a project entitled "A Phase 1, Open-Label, Multiple-Ascending Dose Study of the Safety and Tolerability of CTX-471 in Patients with Inadequate Responses to PD-1/PD-L1 Checkpoint Inhibitors in Metastatic or Locally Advanced Malignancies." Total funding will be $298,465.

Jennifer Choe of Medical Oncology has received an award from Genmab A/S for a project entitled "Analysis of AXL expression in radiation-resistant head and neck squamous cells carcinoma (HNSCC)." Total funding will be $176,496.

Jeffrey Clarke of Medical Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "Phase III, Randomized, Placebo-controlled, Double-blind, Multi-center, International Study of Durvalumab Following Stereotactic Body Radiation Therapy (SBRT) (PACIFIC-4/RTOG-3515)." Total funding will be $1,027,085.

Jeffrey Clarke of Medical Oncology has received an award from GlaxoSmithKline for a project entitled "A Phase 1b/2a Pilot Randomized Study to Evaluate the Safety andTolerability of Autologous T-Cells Expressing Enhanced TCRs (T-Cell Receptors) Specific for NY-ESO-1/LAGE-1a (GSK3377794) Alone, or in Combination with Pembrolizumab in HLA-A2+ Participa." Total funding will be $783,608.

Susan Dent of Medical Oncology has received an award from F. Hoffmann-La Roche Ltd for a project entitled "A PHASEIB/III STUDY OF IPATASERTIB PLUS PALBOCICLIB AND FULVESTRANT VERSUS PLACEBO PLUS PALBOCICLIB AND FULVESTRANT IN HORMONE RECEPTOR POSITIVE AND HER2 NEGATIVE LOCALLY ADVANCED UNRESECTABLE OR METASTATIC BREAST CANCER." Total funding will be $288,827.

Brent Hanks of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "Investigation of a Novel PD-L1:NLRP3 Inflammasome Activation Pathway as a Driver of Metastatic Recurrence." Total funding will be $386,836.

Michael Morse of Medical Oncology has received an award from AstraZeneca AB for a project entitled "A Phase III Randomized, Double-Blind, Placebo Controlled, Multi-centre Study of Durvalumab Monotherapy or in Combination with Bevacizumab as Adjuvant Therapy in Patients with Hepatocellular Carcinoma Who Are at High Risk of Recurrence After Curative." Total funding will be $356,576.

April Salama of Medical Oncology has received an award from Bristol-Myers Squibb Company for a project entitled "BMS Rollover (CA2098TT)." Total funding will be $133,147.

Jason Somarelli of Medical Oncology has received an award from Dolphin Quest for a project entitled "Dolphin Quest: Scholars - An integrated comparative physiology and genomics approach to understand dolphin adaptation to hypoxia." Total funding will be $10,000.

Jason Somarelli of Medical Oncology has received an award from Dolphin Quest for a project entitled "Dolphin Quest: An integrated comparative physiology and genomics approach to understand dolphin adaptation to hypoxia." Total funding will be $5,000.

Christina Barkauskas of Pulmonary has received an award from Boehringer Ingelheim Corporation for a project entitled "Elucidation of regional variability in the transcriptome and proteome of cellular subsets in IPF." Total funding will be $499,758.

Omar Mohamedaly of Pulmonary has received an award from Vertex Pharmaceuticals Inc. for a project entitled "VX18-445-113 A Phase 3 open label study evaluating the long term safety of VX-445 combination therapy in subjects with cystic fibrosis." Total funding will be $100,662.