New funding awards - February 2019

Monday, March 11, 2019

Sponsored Research

William Jones of Cardiology has received a sub-award (1015006) through the Vanderbilt University Medical Center for a project entitled "Leveraging Big Data for Small Patients." Total funding will be $4,644.

James Bain of Endocrinology has received a sub-award (1R01-1DK117491-01-REVISED) through the Northwestern University for a project entitled "Predicting Newborn and Childhood Adiposity: An Integrated Omics Approach." Total funding will be $234,448.

Ashot Sargsyan (Mentor: Mark Herman) of Endocrinology has received an award from the American Diabetes Association for a project entitled "The Role of HGFAC in Lipid and Glucose Homeostasis." Total funding will be $57,958.

Guofang Zhang of Endocrinology has received an award from the Propionic Acidemia Foundation for a project entitled "Propionyl-CoA and propionycarnitine-mediated cardiac complication in patients with propionic acidemia." Total funding will be $48,500.

Rodger Liddle of Gastroenterology has received an award (1R01-DK120555-01) from the National Institutes of Health for a project entitled "Mechanisms of mechanically-induced acute pancreatitis." Total funding will be $1,810,688.

Thomas Leblanc of Hematologic Malignancies and Cellular Therapy has received a sub-award (R01-CA222014-01A1) through the Massachusetts General Hospital for a project entitled "Randomized Trial of Inpatient Palliative Care for Patients with Hematologic Malignancies Undergoing Hematopoietic Stem Cell Transplantation." Total funding will be $128,802.

Dorothy Sipkins of Hematologic Malignancies and Cellular Therapy has received an award from the American Cancer Society, Inc. for a project entitled "Targeting Dormant Breast Cancer Micrometastases to Prevent Disease Relapse." Total funding will be $238,000.

Jason Stout of Infectious Diseases has received a sub-award () through the NC Department of Health and Human Services for a project entitled "Epidemiology/General Communicable Disease Control." Total funding will be $85,933.

Ephraim Tsalik of Infectious Diseases has received an award (1PC1-AI134343-02) from the National Institutes of Health for a project entitled "AMR Challenge Award 2." Total funding will be $100,000.

Gerard Blobe of Medical Oncology has received an award (1R01-CA236843-01) from the National Institutes of Health for a project entitled "Role for TbetaRIII Shedding in the Tumor Microenvironment." Total funding will be $1,677,025.

Steven Crowley of Nephrology has received an award (1R01-DK118019-01A1) from the National Institutes of Health for a project entitled "The interleukin-1 receptor regulates crosstalk between myeloid and renal tubular cells in hypertension." Total funding will be $1,746,965.

Xunrong Luo of Nephrology has received an award (7R01-AI114824-04) from the National Institutes of Health for a project entitled "Modeling concurrent cytomegalovirus infection and transplantation tolerance." Total funding will be $562,917.

Weibin Zhou of Nephrology has received a sub-award (P30-DK090868-) through the University of Maryland, Baltimore County for a project entitled "Screening for Genetic Modifiers of ADPKD Using Gynogenetic Haploid Zebrafish." Total funding will be $39,999.

Jamie Todd of Pulmonary has received a sub-award (5U01-AI063594-15) through the Mount Sinai School of Medicine for a project entitled "Lung Tissue Gene Expression Profiling in Chronic Lung Allograft Dysfunction-CTOT." Total funding will be $126,872.

Industry-sponsored Clinical Trials

Adam DeVore of Cardiology has received an award from AstraZeneca AB for a project entitled "DELIVER HF EHR SCREENING INITIATIVE." Total funding will be $280,807.

Terry Fortin of Cardiology has received an award from United Therapeutics Corporation for a project entitled "APD 811-301 - Phase III." Total funding will be $80,888.

William Herzog of Cardiology has received an award from CSL Behring LLC for a project entitled "A Phase 3, Multicenter, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Investigate the Efficacy and Safety of CSL112 in Subjects with Acute Coronary Syndrome." Total funding will be $543,167.

William Jones of Cardiology has received an award from Abbott Cardiovascular Systems, Inc. for a project entitled "A PROSPECTIVE, MULTI-CENTER, SINGLE-ARM INVESTIGATIONAL STUDY IN HIGH OR EXTREME RISK PATIENTS WITH SYMPTOMATIC, SEVERE NATIVE AORTIC STENOSIS." Total funding will be $497,399.

Thomas Povsic of Cardiology has received an award from Caladrius Biosciences, Inc. for a project entitled "CD34+ Biologics." Total funding will be $94,204.

Paul Rosenberg of Cardiology has received an award from Luitpold Pharmaceuticals for a project entitled "A Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Injectafer (Ferric Carboxymaltose) as Treatment for Heart Failure with Iron Deficiency.." Total funding will be $287,529.

Chiara Melloni of Clinical Pharmacology has received an award from Bristol-Myers Squibb Company for a project entitled "Safety and Effectiveness of Direct Oral Anticoagulants in Patients with Atrial Fibrillation and Cancer." Total funding will be $744,154.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Daiichi Sankyo Inc for a project entitled "A Phase I Study of DS-3201B in Subjects With Acute Myelogenous Leukemia (AML) Or Acute Lymphocytic Leukemia (ALL)." Total funding will be $522,242.

Mitchell Horwitz of Hematologic Malignancies and Cellular Therapy has received an award from CSL Behring LLC for a project entitled "A Phase 2/3, Multicenter, randomized, double-blind, placebo-controlled, study to evaluate the safety and efficacy of Alpha-! Antitrypsin for the Prevention of GVHD." Total funding will be $329,083.

Thomas Leblanc of Hematologic Malignancies and Cellular Therapy has received an award from Carevive Systems, Inc. for a project entitled "Understanding Barriers to Oral Therapy Adherence in Adult/Older-Adult AML Patients (429 Oral)." Total funding will be $32,843.

Rahima Zennadi of Hematology has received an award from GlycoMimetics, Inc for a project entitled "GMI Technology vascular occlusion evaluation." Total funding will be $313,988.

Joshua Thaden of Infectious Diseases has received an award from Janssen Research & Development, LLC for a project entitled "Janssen ExPEC Study." Total funding will be $46,769.

Brent Hanks of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "HSP70-TLR4-mediated MDSC Recruitment as an Adaptive Resistance." Total funding will be $488,324.

Brent Hanks of Medical Oncology has received an award from Leap Therapeutics, Inc. for a project entitled "Investigating the Immunotherapeutic Properties of the DKK1 Antibody, DKN-01, in Pre-Clinical Models of Melanoma." Total funding will be $136,537.

April Salama of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Multicenter, Open label, Phase III Extension Trial to Study the Long-term Safety and Efficacy in Participants with Advanced Tumors Who Are Currently on Treatment or in Follow-up in a Pembrolizumab Trial.." Total funding will be $242,517.

Thomas Stinchcombe of Medical Oncology has received an award from Advaxis Inc for a project entitled "A Phase 1/2, Open-Label Study of ADXS-503 Alone and in Combination with Pembrolizumab in Subjects with Metastatic Squamous or Non-Squamous Non-Small Cell Lung Cancer." Total funding will be $374,789.

John Reynolds of Pulmonary has received an award from BREATH Therapeutics for a project entitled "A phase III clinical trial to demonstrate the effectiveness and safety of Liposomal Cyclosporine A (L-CsA) inhalation solution delivered via the PARI Investigational eFlow device plus standard of care v. standard of care of BOS in double lung transpl." Total funding will be $132,500.

John Reynolds of Pulmonary has received an award from BREATH Therapeutics for a project entitled "A phase III clinical trial to demonstrate the effectiveness and safety of Liposomal Cyclosporine A (L-CsA) inhalation solution delivered via the PARI Investigational eFlow device plus standard of care v. standard of care of BOS in single lung transpl." Total funding will be $88,547.

Robert Tighe of Pulmonary has received an award from Genentech, Inc. for a project entitled "Genentech Xenon MRI IPF Study." Total funding will be $425,000.