New funding awards - January 2021

Monday, February 22, 2021

Sponsored Research

Paul Agris of Cardiology has received an award (W81XWH-16-1-0428) from the Department of Defense for a project entitled "Biochemical Consequences of Cdka I I Mutation that Result in Unprocessed, Nonfunctional Insulin and Type 2 Diabetes." Total funding will be $147,632.

Deborah Muoio of Endocrinology has received a sub-award (2R01-DK091538-12A1) through the University of Minnesota for a project entitled "Ketone Body Metabolism and Integrated Metabolic Homeostasis." Total funding will be $119,430.

Guofang Zhang of Endocrinology has received an award from the Propionic Acidemia Foundation for a project entitled "Propionyl-CoA and propionycarnitine-mediated cardiac complication in patients with propionic acidemia." Total funding will be $51,500.

Diego Bohorquez of Gastroenterology has received an award (3R21-AT010818-02S1) from the National Institutes of Health for a project entitled "The efferent synapse in neuropod cells." Total funding will be $55,500.

Deborah Fisher of Gastroenterology has received an award from the Freenome Holdings, Inc. for a project entitled "PREEMPT CRC: PREvention Employing a Multiomics Plasma-based Test for ColoRectal Cancer." Total funding will be $128,199.

James Davis of General Internal Medicine has received a sub-award (OISE-20-66590-1) through the University of Wisconsin - Madison for a project entitled "Smoking Status and COVID-19 Complications." Total funding will be $48,240.

Rowena Dolor of General Internal Medicine has received a sub-award (1-R61AG0684-01) through the University of Texas - Southwestern for a project entitled "Preventing Cognitive Decline by Reducing BP Target Trial (PCOT)." Total funding will be $125,802.

Nia Mitchell of General Internal Medicine has received a sub-award (5P30-DK020593-43) through the Vanderbilt University Medical Center for a project entitled "Formative research to develop a framework for integrating TOPS into CHCs in the Southeastern United States." Total funding will be $40,250.

Lori Orlando of General Internal Medicine has received a sub-award (1U01-HG011166-01) through the Vanderbilt University Medical Center for a project entitled "The Electronic Medical Records and Genomics (eMERGE) Genomic Risk Assessment and Management Network-Coordinating Center." Total funding will be $145,789.

Thomas Ortel of Hematology has received a sub-award (1OT2HL156812-01) through the Research Triangle Institute International for a project entitled "ACTIV IV COVID-19 Post-hospital Thrombosis Prevention Study." Total funding will be $913,082.

Jason Stout of Infectious Diseases has received a sub-award () through the NC DHHS for a project entitled "Epidemiology/General Communicable Disease Control." Total funding will be $887,220.

Chris Woods of Infectious Diseases has received a sub-award () through the Institute for Medical Research, Inc. for a project entitled "IMR PSA - Deborah Murray Ensemble Study." Total funding will be $37,389.

Chris Woods of Infectious Diseases has received a sub-award () through the Institute for Medical Research, Inc. for a project entitled "IMR PSA - Tyffany Locklear Ensemble Study." Total funding will be $18,848.

Carey Anders of Medical Oncology has received an award from the 5 for the Fight for a project entitled "Dr. Anders-Cancer Research." Total funding will be $1,866.

Andrew Nixon of Medical Oncology has received a sub-award (3U10-CA180868-06S1R) through the NRG Oncology for a project entitled "Angiome Profiling of GY012." Total funding will be $1.

Allison Ashley-Koch of Nephrology has received a sub-award (1 OT3 HL147154-01) through the National Heart, Lung, and Blood Institute for a project entitled "Modeling Sickle Cell Disease phenotypes through supervised learning of patient multi-omic data." Total funding will be $54,663.

Megan Clowse of Rheumatology has received an award from the Rheumatology Research Foundation for a project entitled "Moving the ACR's Reproductive Health Guidelines into Practice." Total funding will be $400,000.

Industry-sponsored Clinical Trials

Adam DeVore of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Prospective comparison of ARNI with ARB given following stabilization in decompensated HFpEF (PARAGLIDE)." Total funding will be $813,330.

Marat Fudim of Cardiology has received an award from NXT Biomedical for a project entitled "Feasibilityof transcatheter cannulation and drainage of the thoracic duct in patients with Congestive Heart Failure  Lymph Drainage in CHF Fluid Overload." Total funding will be $100,000.

Donald Hegland of Cardiology has received an award from Medtronic, Inc. for a project entitled "EP Fellows Research Fund." Total funding will be $25,000.

Donald Hegland of Cardiology has received an award from Boston Scientific Corporation for a project entitled "EP Fellows Research Fund." Total funding will be $15,000.

Mitchell Krucoff of Cardiology has received an award from Boston Scientific Corporation for a project entitled "RAPID Funding Letter." Total funding will be $50,000.

Jane Onken of Gastroenterology has received an award from Arena Pharmaceuticals, Inc. for a project entitled "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 52-Week Study to Assess the Efficacy and Safety of Etrasimod in Subjects with Moderately to Severely Active Ulcerative Colitis." Total funding will be $232,220.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Takeda Pharmaceutical Company Limited for a project entitled "Triple Combination of Pevonedistat and Venetoclax Plus Azacitidine in Adults With Acute Myeloid Leukemia Who Are Unfit for Intensive Chemotherapy." Total funding will be $1,210,356.

Mehri McKellar of Infectious Diseases has received an award from ViiV Healthcare for a project entitled "Phase IIIb study evaluating switching to long acting Cabo+long acting Rilp Q2months in HIV adults who are virally suppressed." Total funding will be $304,914.

Andrew Armstrong of Medical Oncology has received an award from Celgene Corporation for a project entitled "A PHASE 1, MULTI-CENTER, OPEN-LABEL, DOSE FINDING STUDY TO EVALUATE THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF CC-94676 IN SUBJECTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER." Total funding will be $1,883,900.

Jennifer Choe of Medical Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "A Phase II, Multicenter, Open-label Study to Evaluate the Efficacy and Safety of Trastuzumab Deruxtecan (T-DXd, DS-8201a) for the Treatment of Selected HER2-expressing Tumors (DESTINY-PanTumor02)." Total funding will be $399,087.

Neal Ready of Medical Oncology has received an award from AbbVie Inc. for a project entitled "A Phase 1 Study of ABBV-011 as a Single-Agent and in Combination with Budigalimab (ABBV-181) in Subjects with Relapsed or Refractory Small Cell Lung Cancer." Total funding will be $1,871,475.

Thomas Stinchcombe of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "Phase 2 Basket Study of Tucatinib in Combination with Trastuzumab in Subjects with Previously Treated, Locally-Advanced Unresectable or Metastatic Solid Tumors Driven by HER2 Alterations." Total funding will be $230,649.

Matthew Sparks of Nephrology has received an award from Renal Research Institute, LLC for a project entitled "Hepato-renal Regulation of Water Conservation in Salt-sensitive and Renal Hypertension." Total funding will be $117,275.

Yuh Chin Huang of Pulmonary has received an award from Windtree Therapeutics, Inc for a project entitled "02-CL-2001a A Multicenter single treatment study to assess the safety and tolerability of lyophilized lucinactant in adults with COVID19 associated acute lung injury." Total funding will be $206,052.

Timothy McMahon of Pulmonary has received a sub-award (1R41-OD026688-01A1) through Zenalux Biomedical, Inc. for a project entitled "A portable multi-parametric optical spectroscopy device for key vascular and metabolic endpoints monitoring in small animals." Total funding will be $71,479.

Laurie Snyder of Pulmonary has received an award from AstraZeneca LP for a project entitled "AZ Pulse Ox Study_LOI." Total funding will be $226,109.