New funding awards - July 2017

Friday, August 4, 2017

Sponsored Research

Adrian F. Hernandez of Cardiology has received a sub-award through the Genetic Alliance for a project entitled "Genetic Alliance Subcontract - Support Smart IRB." Total funding will be $10,733.

Robert J. Mentz of Cardiology has received an award from the American Heart Association for a project entitled "Target-HF-CM."

Sudarshan Rajagopal of Cardiology has received an award from the American Heart Association for a project entitled "Regulation of VEGFR3 signaling by Beta-Arrestins in Pulmonary Hypertension." Total funding will be $77,000.

Svati H. Shah of Cardiology has received an award from the American Heart Association for a project entitled "Basic Study."

James W. Wisler of Cardiology has received an award (1K08-HL133488-01) from the National Institutes of Health for a project entitled "Mechanistic studies of Mas receptor activation and its role in aortic aneurysm formation." Total funding will be $769,104.

Matthew D. Hirschey of Endocrinology, Metabolism, and Nutrition has received an award from the Friedreich's Ataxia Research Alliance for a project entitled "Protein Biomarkers in FRDA Cardiomyopathy to Monitor Disease Progression and Therapeutic Efficacy." Total funding will be $100,000.

Jenny Tong of Endocrinology, Metabolism, and Nutrition has received an award through Wake Forest University for a project entitled "WFU Research Agreement." Total funding will be $10,332.

Diego Bohorquez of Gastroenterology has received an award (1R03-DK114500-01) from the National Institutes of Health for a project entitled "Tasting gut bacteria." Total funding will be $159,000.

Andrew J. Muir of Gastroenterology has received a sub-award through the University of Florida for a project entitled "A Phase 3b, Multi-Center, Randomized, Open-Label, Pragmatic Study of Glecaprevir/Pibrentasvir (G/P) +/- Ribavirin for GT1 Subjects with Chronic Hepatitis C Previously Treated with an NS5A Inhibitor + Sofosbuvir Therapy." Total funding will be $40,183.

Amy J. Petty (Mentor: Yiping Yang) of Hematological Malignancies and Cellular Therapy has received an award (F30-CA213799-01A1) from the National Institutes of Health for a project entitled "Role of hedgehog signaling in tumor-associated macrophage polarization." Total funding will be $154,992.

John A. Bartlett of Infectious Diseases has received a sub-award through the Wake County Human Services for a project entitled "Ryan White HIV Adult ID Services, Year 9." Total funding will be $272,816.

Micah T. McClain of Infectious Diseases has received an award (1R21-AI132978-01) from the National Institutes of Health for a project entitled "Host-derived biomarker signatures to differentiate acute viral, bacterial, and fungal infection." Total funding will be $397,500.

Micah T. McClain of Infectious Diseases has received an award from Cystic Fibrosis Foundation Therapeutics, Inc. for a project entitled "Biomarker signatures for diagnosis of acute respiratory syndromes in CF." Total funding will be $161,638.

Mehri McKellar of Infectious Diseases has received an award from the NC DHHS for a project entitled "Choosing Life: Empowerment Action! Results! (CLEAR)." Total funding will be $124,622.

Herbert I. Hurwitz of Medical Oncology has received an award from Academic and Community Cancer Research United for a project entitled "BACCI: A Phase II Randomized, Double-Blind, Placebo-Controlled Study of Capecitabine Bevacizumab plus Atezolizumab versus Capecitabine Bevacizumab plus Placebo in Patients with Refractory Metastatic Colorectal Cancer." Total funding will be $305,708.

Andrew B. Nixon of Medical Oncology has received a sub-award through the University of North Carolina - Chapel Hill for a project entitled "Blood-based Biomarker Profiling for Regorafenib in Metastatic Colorectal Cancer." Total funding will be $57,081.

Steven Patierno of Medical Oncology has received an award (1R01-CA220314-01) from the National Institutes of Health for a project entitled "Race-related alternative splicing: novel targets in prostate cancer." Total funding will be $1,751,081.

John P. Middleton of Nephrology has received a sub-award (4U01-DK099933-04) through the University of Utah for a project entitled "Oral Sodium Bicarbonate to Slow Chronic Kidney Disease Progression." Total funding will be $9,584.

Emily Clausen (Mentor: Scott M. Palmer) of Pulmonary, Allergy, and Critical Care Medicine has received an award from Cystic Fibrosis Foundation Therapeutics, Inc. for a project entitled "Impact of patient specific factors on CF lung transplant outcomes." Total funding will be $46,250.

Omar Mohamedaly (Mentor: Alice L. Gray) of Pulmonary, Allergy, and Critical Care Medicine has received an award from Cystic Fibrosis Foundation Therapeutics, Inc. for a project entitled "Duke CFF PACE Application." Total funding will be $40,986.

Laurie D. Snyder of Pulmonary, Allergy, and Critical Care Medicine has received an award from Cystic Fibrosis Foundation Therapeutics, Inc. for a project entitled "Cystic Fibrosis Lung Transplant Consortium." Total funding will be $135,000.

Laurie D. Snyder of Pulmonary, Allergy, and Critical Care Medicine has received an award from Cystic Fibrosis Foundation Therapeutics, Inc. for a project entitled "The interface of B and T cells in Transplant." Total funding will be $162,000.

Lorenzo Zaffiri of Pulmonary, Allergy, and Critical Care Medicine has received an award from the International Society for Heart & Lung Transplantation for a project entitled "Predictors and Outcomes of Post-transplant lymphoproliferative disorder in lung transplant recipients." Total funding will be $7,500.

Industry-sponsored Clinical Trials

Tristram D. Bahnson of Cardiology has received an award from Biosense Webster Inc for a project entitled "PRECEPT." Total funding will be $147,362.

Camille G. Frazier-Mills of Cardiology has received an award from Medtronic, Inc. for a project entitled "MICRA Trans-Catheter." Total funding will be $3,000.

Christopher Holley of Cardiology has received an award from Athghin Biotechnology, Inc for a project entitled "Mass Spectrometric Screening of the Effect of Chemical Toxicants on the Human Epitranscriptome during Stem Cell Differentiation." Total funding will be $97,005.

Kevin P. Jackson of Cardiology has received an award from Medtronic, Inc. for a project entitled "Attain Stability Quad Model 4798." Total funding will be $75,537.

William S. Jones of Cardiology has received an award from Volcano Corporation for a project entitled "DEFINE-PCI." Total funding will be $74,498.

Han W. Kim of Cardiology has received an award from Guerbet for a project entitled "Guerbet Educational Grant." Total funding will be $5,000.

Renato D. Lopes of Cardiology has received an award from Eli Lilly and Company for a project entitled "Lilly GPGB Diabetes Study." Total funding will be $189,754.

Martin A. Moseley III of Cardiology has received an award from Thermo Finnigan LLC for a project entitled "Ring Trial for Biocrates p180 Q Exactive Targeted Metabolomics Kit." Total funding will be $89,234.

Chetan B. Patel of Cardiology has received an award from Roche Diagnostics for a project entitled "GUIDing Evidence Based Therapy Using Biomarker Intensified Treatment in Heart Failure." Total funding will be $25,200.

Eric D. Peterson of Cardiology has received an award from Abiomed for a project entitled "STEMI HF Outcomes." Total funding will be $70,001.

Sunil V. Rao of Cardiology has received an award from Abbott Vascular Structural Heart for a project entitled "Duke Heart Center General Cardiology Update - A Case-Based Review." Total funding will be $5,000.

Sunil V. Rao of Cardiology has received an award from Boston Scientific Corporation for a project entitled "Duke Heart Center General Cardiology Update - A Case-Based Review." Total funding will be $3,000.

Paul S. Jowell of Gastroenterology has received an award from Medtronic, Inc. for a project entitled "Medtronic SharkCore Needle - a prospective randomized study to examine the diagnostic accuracy of the Sharkcare versus the standard EUS needle in patients identified to have a hypoechoic solid tumor." Total funding will be $57,064.

Carlos M. Decastro of Hematological Malignancies and Cellular Therapy has received an award from Ra Pharmaceuticals, Inc for a project entitled "RA101495-01.203: A Phase 2 Multicenter, Open-Label, Uncontrolled Study to Evaluate the Safety, Tolerability, Efficacy, Pharmaqcokinetics, and Pharm." Total funding will be $103,385.

Carlos M. Decastro of Hematological Malignancies and Cellular Therapy has received an award from Ra Pharmaceuticals, Inc for a project entitled "RA101495-01.202: A multicenter, Open-Label, Uncontrolled, Extension Study of RA101495 in Subjects with Paroxysmal Nocturnal Hemoglobinuria Who Have Completed a RA101495 Clinical Study." Total funding will be $96,328.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from AbbVie Inc. for a project entitled "A Randomized, Double-Blind, Placebo Controlled Study of Venetoclax in Combination with Azacitidine Versus Azacitidine in Treatment Naive Subjects with Acute Myeloid Leukemia Who Are Ineligible for Standard Induction Therapy." Total funding will be $482,420.

Thomas L. Ortel of Hematology has received an award from Diagnostica Stago for a project entitled "U.S. External Site Protocol for Evaluation of Precision Performances of STA-THROMBIN ON STA-SATELLITE." Total funding will be $8,263.

Vance G. Fowler of Infectious Diseases has received an award from Genentech, Inc. for a project entitled "ID Project." Total funding will be $34,225.

Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-380-4030." Total funding will be $195,415.

Mehri McKellar of Infectious Diseases has received an award from ViiV Healthcare for a project entitled "A Phase III, randomized, multicentre, parallel-group, non-inferiority study evaluating the efficacy, safety, and tolerability of switching to dolutegravir plus lamivudine in HIV-1 infected adults who are virologically suppressed." Total funding will be $163,149.

John Perfect of Infectious Diseases has received an award from Astellas Pharma Inc. for a project entitled "Study Isavuconazole in a Rabbit Model of Cryptococcal Meningoencephalitis Caused by Cryptococccal gattii." Total funding will be $140,880.

Niharika B. Mettu of Medical Oncology has received an award from ARMO BioSciences for a project entitled "A Randomized Phase 3 Study of AM0010 in Combination with FOLFOX Compared with FOLFOX Alone as Second-line Therapy in Patients with Metastatic Pancreatic Cancer that has Progressed During or Following a First-Line Gemcitabine Containing Regimen." Total funding will be $1,081,031.

Neal E. Ready of Medical Oncology has received an award from AbbVie Inc. for a project entitled "M16-298 (MERU)." Total funding will be $371,575.

Richard F. Riedel of Medical Oncology has received an award from Ignyta for a project entitled "STARTRK-2." Total funding will be $187,382.

Richard F. Riedel of Medical Oncology has received an award from Tracon Pharmaceuticals, Inc. for a project entitled "TRC105:105SAR301." Total funding will be $149,541.

Patricia Lugar of Pulmonary, Allergy, and Critical Care Medicine has received an award from CSL Behring LLC for a project entitled "Outcomes of antibody replacement in immune deficient pregnant women." Total funding will be $20,000.

Kamran Mahmood of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Olympus Corporation for a project entitled "Current Trends in Pleural Disease Management 2017." Total funding will be $5,000.

Kamran Mahmood of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Richard Wolf Medical Instruments Corporation for a project entitled "Current Trends in Pleural Disease Management 2017." Total funding will be $3,000.

Momen Wahidi of Pulmonary, Allergy, and Critical Care Medicine has received an award from FUJIFILM Medical Systems U.S.A., Inc. for a project entitled "EBUS and Navigation Bronchoscopy Course." Total funding will be $2,000.

Virginia B. Kraus of Rheumatology and Immunology has received an award from Bayer Corporation for a project entitled "Evaluation of Anti-inflammatory effects of naproxen sodium on human osteoarthritis synovial cells." Total funding will be $243,995.

Jennifer Rogers of Rheumatology and Immunology has received an award from Janssen Pharmaceutical, Inc. for a project entitled "Phase I MAD Study of JNJ-55920839." Total funding will be $91,168.