New funding awards - July 2019

Friday, August 9, 2019

Sponsored Research

Yongmei Liu of Cardiology has received a sub-award (5R01-MD011721-02 & 03) through the University of Michigan for a project entitled "RACE/ETHNICITY, DNA METHYLATION, AND DISPARITIES IN CARDIOVASCULAR MORTALITY: NHANES 1999-2002." Total funding will be $1,109,219.

Howard Rockman of Cardiology has received an award (2R01-HL056687-22) from the National Institutes of Health for a project entitled "Mechanisms of Maladaptation in Heart Failure." Total funding will be $3,018,840.

Svati Shah of Cardiology has received an award (1R01- HL146145-01A1) from the National Institutes of Health for a project entitled "Clinical and Molecular Epidemiology of High Risk Coronary Plaque." Total funding will be $4,814,478.

Jonathan Stiber of Cardiology has received an award from the American Heart Association for a project entitled "Role of Debrin in Vascular Smooth Muscle Transdifferentiation." Total funding will be $100,000.

Kenneth Schmader of Geriatrics has received an award from the Institute for Medical Research, Inc. for a project entitled "PSA- Susan Doyle." Total funding will be $92,906.

Mitchell Horwitz of Hematologic Malignancies and Cellular Therapy has received a sub-award (5U24-HL138660-02) through the National Marrow Donor Program for a project entitled "C10162: Duke University-BMT CTN 1704 protocol study (CHARM)." Total funding will be $7,411.

Mitchell Horwitz of Hematologic Malignancies and Cellular Therapy has received a sub-award () through the National Marrow Donor Program for a project entitled "A Randomized, Multicenter, Phase III Trial of Tacrolimus/Methotrexate versus Post-Transplant Cyclophosphamide/Tacrolimus/Mycophenolate Mofetil in Non-Myeloablative/Reduced Intensity Conditioning Allogeneic Peripheral Blood Stem Cell." Total funding will be $1.

Anthony Sung of Hematologic Malignancies and Cellular Therapy has received an award (1R21-AG066388-01) from the National Institutes of Health for a project entitled "Evaluating Effects of Age-related Microbiota Modulations in Hematopoietic Stem Cell Transplant Patients." Total funding will be $442,750.

Charity Oyedeji (Mentor: John Strouse) of Hematology has received an award from the American Society of Hematology for a project entitled "2019 ASH RTAF." Total funding will be $70,000.

James White of Hematology has received an award from the University of North Carolina - Chapel Hill for a project entitled "Research Agreement_UNC." Total funding will be $50,000.

Thuy Le of Infectious Diseases has received an award (1R01-AI143409-01A1) from the National Institutes of Health for a project entitled "Making an early diagnosis of talaromycosis - an approach to reduce morbidity and mortality in advanced HIV infection in Southeast Asia." Total funding will be $2,829,718.

Mehri McKellar of Infectious Diseases has received a sub-award () through the Southern AIDS Coalition for a project entitled "Educational program -Southern AIDS Coalition." Total funding will be $10,000.

Wendy Prudhomme - O'Meara of Infectious Diseases has received an award (1R01-AI146849-01) from the National Institutes of Health for a project entitled "Once bitten: A longitudinal, observational study of successful malaria parasite transmission events between humans and mosquitos." Total funding will be $2,916,839.

Steve Taylor of Infectious Diseases has received an award (1R03-AI146406-01) from the National Institutes of Health for a project entitled "Estimating the incremental benefits on active malaria case detection of high-sensitivity rapid diagnostic tests." Total funding will be $161,000.

Scott Antonia of Medical Oncology has received a sub-award (1U01-CA232382-01) through the H. Lee Moffitt Cancer Center & Research Institute for a project entitled "Eco-Evolutionary dynamics of NSCLC to immunotherapy: Response and Resistance." Total funding will be $31,716.

Jeffrey Clarke of Medical Oncology has received a sub-award () through the H. Lee Moffitt Cancer Center & Research Institute for a project entitled "Radiation and Chemotherapy with Ipilimumab followed by Nivolumab for Patients with Stage III Unresectable NSCLC." Total funding will be $130,488.

Daniel George of Medical Oncology has received an award (PC180980  W81XWH1910458) from the Department of Defense for a project entitled "Race-related germline genetic variation and response to secondary hormonal therapy in metastatic castration-resistant prostate cancer." Total funding will be $1,609,691.

Steven Patierno of Medical Oncology has received an award (W81XWH-14-1-0569) from the Department of Defense for a project entitled "Validation and interrogation of differentially expressed and alternatively spliced genes in African American prostate cancer." Total funding will be $820,658.

Neil Spector of Medical Oncology has received an award from the Bill & Marian Cook Foundation for a project entitled "Eradication of Borrelia burgdoreri infection using immunology/Bartonella and Inflammatory Breast Cancer." Total funding will be $90,000.

Tian Zhang of Medical Oncology has received a sub-award () through the H. Lee Moffitt Cancer Center & Research Institute for a project entitled "Validation of Prostate Cancer Stem Cell Model in First and Second Line Hormone Therapy." Total funding will be $25,000.

Robert Spurney of Nephrology has received an award (PR180545- W81XWH1910314) from the Department of Defense for a project entitled "Promoting Podocyte Protective Natriuretic Peptide Signaling in Proteinuric Kidney Diseases." Total funding will be $1,322,965.

Industry-sponsored Clinical Trials

Brett Atwater of Cardiology has received an award from St. Jude Medical Inc. for a project entitled "Physical Activity Monitoring Predicts Outcomes in HF: Insights from MERLIN." Total funding will be $49,886.

Tristram Bahnson of Cardiology has received an award from Biosense Webster Inc for a project entitled "Evaluation of QDOT MICRO catheter for pulmonary vein isolation (PVI) in subjects with Paroxysmal Atrial Fibrillation (PAF)." Total funding will be $106,238.

Adrian Hernandez of Cardiology has received an award from Verily Life Sciences, LLC for a project entitled "Baseline Research Consortium." Total funding will be $336,295.

Jonathan Piccini of Cardiology has received an award from Spectranetics for a project entitled "IIR Infection Study." Total funding will be $242,632.

Sunil Rao of Cardiology has received an award from Shockwave Medical, Inc. for a project entitled "Shockwave - DISRUPT CAD." Total funding will be $36,000.

Matthew Roe of Cardiology has received an award from Amgen, Inc. for a project entitled "Vesalius Real Registry." Total funding will be $249,000.

Tracy Wang of Cardiology has received an award from Chiesi Farmaceutici SPA for a project entitled "Cangrelor in Acute MI: Effectiveness and Outcomes (CAMEO) Registry." Total funding will be $2,750,202.

Manal Abdelmalek of Gastroenterology has received an award from DURECT Corporation for a project entitled "A Randomized, Open-label, Phase 1b Study to Evaluate Safety, Pharmacokinetic and Pharmacodynamic Signals of DUR-928 in Patients with Non-Alcoholic Steatohepatitis (NASH)." Total funding will be $176,494.

Andrew Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "GS-US-428-4194." Total funding will be $93,433.

Patrick Sullivan of Geriatrics has received an award from Mark Brosso for a project entitled "Testing of PROTEO formulation to reduce brain amyloid beta levels." Total funding will be $658,149.

Mitchell Horwitz of Hematologic Malignancies and Cellular Therapy has received an award from Incyte Corporation for a project entitled "A Phase 3 Study of Itacitinib or Placebo in Combination With Corticosteroids as Initial Treatment for Chronic Graft Versus Host Disease." Total funding will be $93,433.

Marilyn Telen of Hematology has received an award from FORMA Therapeutics, Inc. for a project entitled "Randomized double-blind study of FT-4202 in sickle cell disease." Total funding will be $139,342.

Barbara Alexander of Infectious Diseases has received an award from F2G Ltd for a project entitled "F901318 - Aspergillus." Total funding will be $129,173.

Barbara Alexander of Infectious Diseases has received an award from Scynexis Inc for a project entitled "Scy-078-206." Total funding will be $111,254.

Gayani Tillekeratne of Infectious Diseases has received an award from bioMerieux, Inc. for a project entitled "Assess the performance characteristics of procalcitonin and gene expression classifiers at differentiating between viral and bacterial ARTIs.." Total funding will be $7,424.

Cameron Wolfe of Infectious Diseases has received an award from Hologic, Inc. for a project entitled "CMV Quant Assay." Total funding will be $160,967.

Scott Antonia of Medical Oncology has received an award from Nektar Therapeutics for a project entitled "A PHASE 1/2, OPEN-LABEL, MULTICENTER STUDY OF THE COMBINATION OF NKTR-214 AND NIVOLUMAB OR THE COMBINATION OF NKTR-214, NIVOLUMAB, AND OTHER ANTI-CANCER THERAPIES IN PATIENTS WITH SELECT LOCALLY ADVANCED OR METASTATIC SOLID TUMOR MALIGNANCIES." Total funding will be $416,642.

Jeffrey Clarke of Medical Oncology has received an award from Array BioPharma Inc for a project entitled "A Phase 2, Open-label Study of Encorafenib + Binimetinib in Patients with BRAF V600E-mutant Non-small Cell Lung Cancer." Total funding will be $185,599.

Arif Kamal of Medical Oncology has received a sub-award (HHSN261201700030) through Medable Inc. for a project entitled "Validating TOGETHER CARE, a mobile application ("app") for caregivers to implement home-based follow-up care for cancer survivors." Total funding will be $109,984.

Tian Zhang of Medical Oncology has received an award from Mirati Therapeutics, Inc. for a project entitled "A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma (Mirati 516-003)." Total funding will be $394,809.

Loretta Que of Pulmonary has received an award from Sanofi US for a project entitled "EFC1580 BOREAS: A randomized double blind placebo controlled parallel group 52wk study to assess the efficacy, safety, and tolerability of Dupilumab in patients with moderate to severe COPD w/Type 2." Total funding will be $219,351.

Loretta Que of Pulmonary has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "AZ D5180C00018 DESTINATION: A multicentre double blind randomized placebo controlled parallel group phase 3 safety extension study to evaluate safety & tolerability of Tezepelumab." Total funding will be $79,234.