New funding awards - July 2020

Wednesday, August 26, 2020

Sponsored Research

Christopher Granger of Cardiology has received an award (1 UG3-HL146935-01A1) from the National Institutes of Health for a project entitled "CCC: The Regional Approaches to Cardiovascular Emergencies- Cardiac ARreSt (RACE-CARS) Cluster-Randomized Trial 1/2." Total funding will be $9,627,363.

Sudarshan Rajagopal of Cardiology has received an award (3R01-GM122798-03S1) from the National Institutes of Health for a project entitled "Biasing CXCR3 Signaling to Modulate the Inflammatory Response." Total funding will be $43,713.

Monique Starks of Cardiology has received an award (1K23-HL153889-01) from the National Institutes of Health for a project entitled "Evaluation of the Requirements and Critical Features of a Drone-Deployed AED Network to Radically Improve Community-Level Survival after OHCA." Total funding will be $922,014.

Jonathan Campbell of Endocrinology has received an award (1R01-DK125353-01) from the National Institutes of Health for a project entitled "Novel metabolic actions of GIP." Total funding will be $2,119,580.

Leonor Corsino of Endocrinology has received a sub-award (5P30-DK111022-06) through the Albert Einstein College of Medicine for a project entitled "A Transition of Care Model from Hospital to Community for Hispanic/Latino Adult Patients with Diabetes." Total funding will be $25,000.

Manal Abdelmalek of Gastroenterology has received an award (W81XWH-20-1-0514-CA190216P2) from the Department of Defense for a project entitled "A multidisciplinary study of biological disparities in NASH progression and response to statins to inform personalized liver cancer chemoprevention in NAFLD." Total funding will be $859,744.

Anna Mae Diehl of Gastroenterology has received an award (W81XWH-20-1-0513-CA190216P1) from the Department of Defense for a project entitled "A multidisciplinary study of biological disparities in NASH progression and response to statins to inform personalized liver cancer chemoprevention in NAFLD." Total funding will be $298,917.

Ayako Suzuki of Gastroenterology has received an award (W81XWH-20-1-0512 -CA19021) from the Department of Defense for a project entitled "A multidisciplinary study of biological disparities in NASH progression and response to statins to inform personalized liver cancer chemoprevention in NAFLD." Total funding will be $851,237.

Ranee Chatterjee Montgomery of General Internal Medicine has received a sub-award (1U01-TR003206-01) through the Rockefeller University for a project entitled "Empowering the Participant Voice: Collaborative Infrastructure and Validated Tools for Collecting Participant Feedback to Improve the Clinical Research Enterprise." Total funding will be $72,450.

Kenneth Schmader of Geriatrics has received an award from the Institute for Medical Research, Inc. for a project entitled "PSA- Susan Doyle." Total funding will be $69,007.

Heather Whitson of Geriatrics has received an award from the Centers for Disease Control and Prevention for a project entitled "IPA-Carl Pieper." Total funding will be $26,720.

Luigi Racioppi of Hematologic Malignancies and Cellular Therapy has received an award (W81XWH2010498-BC191370P1) from the Department of Defense for a project entitled "CaMKK2 inhibition as an approach to increase tumor immunity in breast cancers." Total funding will be $1,194,933.

Marilyn Telen of Hematology has received an award from the Doris Duke Charitable Foundation, Inc. for a project entitled "Sharing Comprehensive 'Omics in Sickle Cell Disease Through the NHLBI TOPMed Network." Total funding will be $16,500.

Marilyn Telen of Hematology has received a sub-award (4UH-3HL143192-02) through the University of Pittsburgh for a project entitled "Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE)." Total funding will be $1.

John Bartlett of Infectious Diseases has received an award (2P30-AI064518-16) from the National Institutes of Health for a project entitled "Clinical Core." Total funding will be $1,427,944.

Mehri McKellar of Infectious Diseases has received an award (2P30-AI064518-16) from the National Institutes of Health for a project entitled "Biomedical Prevention Scientific Working Group." Total funding will be $84,071.

Manqi Zhang (Mentor: Gerard Blobe) of Medical Oncology has received an award from the National Cancer Center for a project entitled "Role of ALK4 in Pancreatic Cancer Progression." Total funding will be $40,000.

Tyler A. Allen (Mentor: Steven Patierno) of Medical Oncology has received an award from the American Association for Cancer Research for a project entitled "Interrogating Race-related Alternative Splicing Variation in Metastasis." Total funding will be $120,000.

Zachary Healy of Pulmonary has received an award (1 K99 -AI143927-01A1) from the National Institutes of Health for a project entitled "Characterization of CMV-specific T cell responses in immunocompromised hosts." Total funding will be $258,178.

Industry-sponsored Clinical Trials

Melissa Daubert of Cardiology has received an award from 4D Molecular Therapeutics for a project entitled "Gene Therapy 4D-310 in Adult Males with Fabry Disease." Total funding will be $699,597.

Martin Moseley III of Cardiology has received an award from Circumvent Pharmaceutical for a project entitled "Circumvent Pharmaceutical SRA." Total funding will be $8,800.

Thomas Povsic of Cardiology has received an award from XyloCor Therapeutics for a project entitled "A Phase 1/2 Trial of Direct Administration of AdVEGF-All6A+, a Replication Deficient Adenovirus Vector Expressing a cDNA/Genomic Hybrid of Human Vascular Endothelial Growth Factor, to the Ischemic Myocardium of Subjects with Angina Pectoris Secondary." Total funding will be $286,903.

Jane Onken of Gastroenterology has received an award from Arena Pharmaceuticals, Inc. for a project entitled "A Phase 3, Randomized, Double-Blind, Placebo-Controlled, 52-Week Study to Assess the Efficacy and Safety of Etrasimod in Subjects with Moderately to Severely Active Ulcerative Colitis." Total funding will be $247,126.

Cristina Gasparetto of Hematologic Malignancies and Cellular Therapy has received an award from GlaxoSmithKline for a project entitled "Expanded Access Program ("EAP") for belantamab mafodotin in Patients with Relapsed/Refractory Multiple Myeloma who are Refractory to a Proteasome Inhibitor,and an Immunomodulatory Agent, and an Anti-CD38 Antibody." Total funding will be $72,184.

Lindsay Rein of Hematologic Malignancies and Cellular Therapy has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A Phase 1b, multicenter, open-label dose escalation and expansion platform study of select combinations in adult patients with myelofibrosis." Total funding will be $284,289.

John Perfect of Infectious Diseases has received an award from Amplyx Pharmaceuticals, Inc. for a project entitled "Phase II, study to evaluate the safety of APX001 with Invasive mold infections caused by Aspergillus or rare mold." Total funding will be $254,965.

Chris Woods of Infectious Diseases has received an award from Abbott Disgnostic Scarborough, Inc. for a project entitled "Clinical Evaluation of the ID NOW COVID-19 Assay." Total funding will be $433,937.

Tareq M. Aljurf (Mentor: Aimee Zaas) of Infectious Diseases has received an award from Saudi Arabian Cultural Mission for a project entitled "Duke Internal Medicine Residency Program - Dr. Tareq Aljurf." Total funding will be $298,351.

Daniel George of Medical Oncology has received an award from Bristol-Myers Squibb Company for a project entitled "ODYSSEY RCC." Total funding will be $2,500,000.

Gretchen Kimmick of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "Best Quality of Care from a Distance (BQal-D): Maintaining High Quality Care for Hormone Receptor Positive Metastatic Breast Cancer during the COVID Pandemic." Total funding will be $246,022.

Neal Ready of Medical Oncology has received an award from Genentech, Inc. for a project entitled "A PHASE Ib DOSE-ESCALATION AND DOSEEXPANSION STUDY EVALUATING THE SAFETY, TOLERABILITY, PHARMACOKINETICS, AND EFFICACY OF VENETOCLAX IN COMBINATIONWITH ATEZOLIZUMAB, CARBOPLATIN, AND ETOPOSIDE IN PATIENTS WITH UNTREATED EXTENSIVE-STAGE SMALL CELL LU." Total funding will be $386,947.

Neal Ready of Medical Oncology has received an award from Merck for a project entitled "Pembrolizumab Prior to Surgery for Stage 1B, 2 or 3A Non-small Cell Lung Cancer (NSCLC): A Phase II Study." Total funding will be $331,827.

April Salama of Medical Oncology has received an award from IDEAYA Biosciences for a project entitled "A phase 1/2 study of IDE196 in patients with solid tumors harboring GNAQ/11 mutations or PRKC fusions." Total funding will be $17,130.

John Strickler of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "SGNTUC-024 Tucatinib plus trastuzumab and oxaliplatin-based chemotherapy for HER2+ gastrointestinal cancers." Total funding will be $298,530.

Momen Wahidi of Pulmonary has received an award from CSA Medical, Inc. for a project entitled "SPRAY-CB: A Sham controlled prospective randomized trial of the RejuvenAir system for the treatment of moderate to severe chronic obstructive pulmonary disease with chronic bronchitis." Total funding will be $428,608.