New funding awards - July 2021

Friday, August 20, 2021

Sponsored Research

Sudha Shenoy of Cardiology has received an award from the National Institutes of Health for a project entitled "Regulation of myocardial GPCRs by USP20 in normal and hypertrophied heart." Total funding will be $2,248,260.

Pamela Douglas of Cardiology has received a sub-award through the Massachusetts General Hospital for a project entitled "Randomized Trial to Prevent Vascular Events in HIV (REPRIEVE)." Total funding will be $152,536.

Laura Rupprecht (Mentor: Diego Bohorquez) of Gastroenterology has received an award from the National Institutes of Health for a project entitled "The neurotransmitter for calorie." Total funding will be $219,750.

Stefanie Sarantopoulos of Hematologic Malignancies and Cellular Therapy has received an award from the National Institutes of Health for a project entitled "Pathological B Cells: Novel Strategies to Prevent and Treat Chronic GVHD." Total funding will be $3,663,360.

Andrew E. Whiteley (Mentor: Dorothy Sipkins) of Hematologic Malignancies and Cellular Therapy has received an award from the National Institutes of Health for a project entitled "A Dual Role Of Integrin Alpha-3 In Breast Cancer Cns Metastasis & Chemoresistance (F31)." Total funding will be $114,483.

Hailey M. Harris (Mentor: Gowthami Arepally) of Hematology has received an award from the American Society of Hematology for a project entitled "Role of Complement Receptors in cellualr activation by HIT immune complexes." Total funding will be $42,000.

Susanna Naggie of Infectious Diseases has received an award from the Duke Endowment for a project entitled "TDE Pickett Road Infrastructure." Total funding will be $2,650,000.

Matthew Rubach of Infectious Diseases has received a sub-award through the University of Glasgow for a project entitled "Operationalizing One Health Interventions in Tanzania." Total funding will be $8,785.

Brent Hanks of Medical Oncology has received an award from the National Institutes of Health for a project entitled "Role of the tumor NLRP3 inflammasome in the generation of anti-PD-1 antibody immunotherapy-associated toxicities." Total funding will be $2,001,156.

Scott Antonia of Medical Oncology has received an award from the Department of Defense for a project entitled "Anti-PD1 in combination with an inhibitor of PCSK9 to increase MHC class I molecule expression on tumor cells as immunotherapy for NSCLC." Total funding will be $1,261,854.

Brent Hanks of Medical Oncology has received an award from the Conquer Cancer Foundation for a project entitled "Clinical Biomarker Study of the Tumor NLRP3 Inflammasome and its Role in Anti-PD-1 Immunotherapy Resistance." Total funding will be $450,000.

Claude Piantadosi of Pulmonary has received an award from the Office of Naval Research for a project entitled "Oxidative tissue damage mitigation after exposure to HBO2 using FDA approved anti-epileptic drugs (AEDs)." Total funding will be $988,057.

Momen Wahidi of Pulmonary has received a sub-award through the Vanderbilt University for a project entitled "THO 19102: Navigation endoscopy to reach indeterminate lung nodules versus transthoracic needle aspiration, a randomized controlled study VERITAS." Total funding will be $98,401.

Industry Sponsored Clinical Trials

Andrew Wang of Cardiology has received an award from Evalve, Inc for a project entitled "Percutaneous or Surgical Mitral Valve Repair in Patients with Primary Mitral Regurgitation whose mitral valve has been determined to be suitable for correction by MV repair surgery." Total funding will be $709,025.

Stephen Greene of Cardiology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "PARACOR-19." Total funding will be $671,667.

Andrew Wang of Cardiology has received an award from Cytokinetics, Inc. for a project entitled "AI Algorithm to detect HCM." Total funding will be $200,001.

Kishan Parikh of Cardiology has received an award from Janssen Research & Development, LLC for a project entitled "A Multicenter, Randomized, Double-blind, Placebo-controlled Study in Participants With Sarcoidosis-associated Pulmonary Hypertension (SAPH) to Assess the Efficacy and Safety of Oral Selexipag SPHINX." Total funding will be $92,886.

Jennifer Rymer of Cardiology has received an award from Chiesi USA, Inc for a project entitled "Cangrelor in Acute Myocardial Infarction: Effectiveness and Outcomes Registry." Total funding will be $91,269.

Adam Devore of Cardiology has received an award from Story Health for a project entitled "VIrTuAL Care to Improve Heart Failure Outcomes." Total funding will be $59,750.

David Leiman of Gastroenterology has received an award from Allakos Inc. for a project entitled "A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Studyto Evaluate the Efficacy and Safety of AK002 in Patients with Moderately to Severely Active Eosinophilic Duodenitis who have an Inadequate Response with, Lost Response to, or." Total funding will be $229,274.

Maria Segovia of Gastroenterology has received an award from 9 Meters Biopharma, Inc for a project entitled "A Phase 2, Double-Blind, Double-Dummy, Placebo-Controlled, Multicenter Study of the Efficacy, Safety, and Tolerability of NM-002 in Adult Patients with Short Bowel Syndrome." Total funding will be $117,682.

Andrea Sitlinger of Hematologic Malignancies and Cellular Therapy has received an award from Innate Pharma for a project entitled "US Post-Marketing Retrospective Observational Safety Study of Moxetumomab Pasudotox-tdfk (LUMOXITITM)." Total funding will be $208,699.

Grace Lee of Hematology has received a sub-award through Zymeron Corporation for a project entitled "Rapid point of care diagnostics to detect serologic status of individuals for select viral infections." Total funding will be $13,946.

Nwora Okeke of Infectious Diseases has received a sub-award through PPD Investigator Services, LLC for a project entitled "Adapt Out COVID (ACTIV-2/A5401) - BMS." Total funding has yet to be determined.

Niharika Mettu of Medical Oncology has received an award from Revolution Medicines, Inc for a project entitled "A Phase 1b/2, Open-Label, Multicenter Dose Escalation and Expansion Study of the Combination of RMC-4630 and Cobimetinib in Adult Participants with Relapsed/refractory Solid Tumors with Specific Genomic Aberrations." Total funding will be $308,367.

Richard Riedel of Medical Oncology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "A Phase 1/2 Study of the TRK Inhibitor Selitrectinib (BAY 2731954) in Adult and Pediatric Subjects with Previously Treated NTRK Fusion Cancers." Total funding will be $295,574.

April Salama of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "An Open-label, Phase 2 Basket Study of SEA-CD40 Combination Therapies in Advanced Malignancies." Total funding will be $257,814.

Neal Ready of Medical Oncology has received an award from Bristol-Myers Squibb Company for a project entitled "A Phase 2 Randomized Double-blind Study of Relatlimab plus Nivolumab in Combination with Chemotherapy vs. Nivolumab in Combination with Chemotherapy as First Line Treatment for Participants with Stage." Total funding will be $232,430.

Daniel George of Medical Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "A Phase III Double-Blind, Randomised, Placebo-Controlled Study Assessing the Efficacy and Safety of Capivasertib + Abiraterone Versus Placebo + Abiraterone as Treatment for Patients with De Novo Metas." Total funding will be $204,428.

Andrew Armstrong of Medical Oncology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "DAROL: Darolutamide Observational Study in non-metastatic castration-resistant prostate cancer patients." Total funding will be $98,210.

Matthew Ellis of Nephrology has received an award from Transplant Genomics Inc. for a project entitled "TruGraf Long-term Clinical Outcomes Study - Pro00108037." Total funding will be $411,750.

Jennifer Rogers of Rheumatology has received an award from GlaxoSmithKline for a project entitled "The Health-Related Quality of Life, Fatigue and Health Utility of Patients with Lupus Nephritis." Total funding will be $51,868.