New funding awards - June 2018

Tuesday, July 17, 2018

Sponsored Research

Conrad Hodgkinson of Cardiology has received an award from the Rosenfeld Heart Foundation for a project entitled "Enhancing cardiac reprogramming via TLR3." Total funding will be $99,975.

Megan L. Kelly (Mentor: Christopher Kontos) of Cardiology has received an award from the Triangle Community Foundation for a project entitled "Gertrude Elion Mentored Medical Research Award." Total funding will be $10,000.

Michel Khouri of Cardiology has received an award from the Sloan Kettering Institute for a project entitled "EXCITE." Total funding will be $43,494.

L. Kristin Newby of Cardiology has received an award through Emory University for a project entitled "Investigate metabolic differences in females with PKU after 1 week of dietary intervention in a camp environment." Total funding will be $4,471.

James E. Tcheng of Cardiology has received an award from Mercy Health for a project entitled "Building UDI Into Longitudinal Data for Medical Device Evaluation (BUILD)." Total funding will be $46,000.

John Williams of General Internal Medicine has received a sub-award through Oregon Health & Science University for a project entitled "Peer Review of PCORI's Funded Research." Total funding will be $80,219.

Christopher B. Bowling of Geriatrics has received a sub-award (1R24AG045050) through Kaiser Permanente for a project entitled "Development of a CKD Discordance Index to Identify High Healthcare Utilization." Total funding will be $11,105.

Cathleen S. Colon-Emeric of Geriatrics has received an award (1UH2-AG056925-01) from the National Institutes of Health for a project entitled "Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative (PRIME Collaborative)." Total funding will be $2,022,779.

Stefanie Sarantopoulos of Hematologic Malignancies and Cellular Therapy has received an award from the Department of Defense for a project entitled "Breaking B-Cell Tolerance to Produce Antibodies that Eradicate Leukemias and Lymphomas." Total funding will be $642,500.

Myaing M. Nyunt of Infectious Diseases has received a sub-award through CRDF Global for a project entitled "New tool for seroepidemiology of malaria: US-Myanmar collaborative study." Total funding will be $30,394.

Wendy A. Prudhomme - O'Meara of Infectious Diseases has received an award (1R21-AI133013-01A1) from the National Institutes of Health for a project entitled "Quantifying parasite importation in an epidemic-prone zone of northern Kenya." Total funding will be $357,775.

Ashley Spann (Mentor: Aimee K. Zaas) of Infectious Diseases has received an award from the American College of Physicians for a project entitled "Bridging the Treatment Gap: Improving Time to Cure of Hepatitis C in North Carolina." Total funding will be $2,500.

James Abbruzzese of Medical Oncology has received an award (3UM1-CA186704-04S1) from the National Institutes of Health for a project entitled "Administrative Supplements for National Cancer Institute (NCI) Support of the electronic collection of PRO-CTCAE using Patient Cloud ePRO in the Experimental Therapeutics Clinical Trials NetworkETCTN." Total funding will be $77,352.

Andrew Armstrong of Medical Oncology has received an award (W81XWH-18-1-0280 Log#PC17) from the Department of Defense for a project entitled "Plasma Angiome and Serum Androgens as Predictors of Overall Survival in Metastatic Prostate Cancer." Total funding will be $108,303.

Niharika B. Mettu of Medical Oncology has received an award from Genetech for a project entitled "A Pilot Study Investigating the Effect of Atezolizumab Monotherapy and Atezolizumab plus Cobimetinib on the Tumoral Immunoprofile in Liver Metastases from Colorectal Cancer." Total funding will be $35,772.

Andrew B. Nixon of Medical Oncology has received an award (PC170883P1) from the Department of Defense for a project entitled "Plasma Angiome and Serum Androgens as Predictors of Overall Survival in Metastatic Prostate Cancer." Total funding will be $85,127.

Neil L. Spector of Medical Oncology has received an award from the Bill & Marian Cook Foundation for a project entitled "Eradication of Borrelia burgdoreri infection using immunology/Bartonella and Inflammatory Breast Cancer." Total funding will be $70,000.

Thomas Stinchcombe of Medical Oncology has received an award from the Dana-Farber Cancer Institute for a project entitled "A Phase 2 Study of osimertinib in combination with selumetinib in EGFR inhibitor naive advanced EGFR mutant lung cancer." Total funding will be $101,500.

John P. Middleton of Nephrology has received a sub-award (4U01-DK099933-04) through the University of Utah for a project entitled "Oral Sodium Bicarbonate to Slow Chronic Kidney Disease Progression." Total funding will be $9,584.

Industry-sponsored Clinical Trials

Robert W. Harrison of Cardiology has received an award from Novartis Consumer Health, Inc. for a project entitled "Prospective ARNI verses ACE inhibitor trial to determine superiority in reducing heart failure events after MI." Total funding will be $117,037.

Adrian F. Hernandez of Cardiology has received an award from scPharmaceuticals for a project entitled "Subcutaneous Furosemide in Acute Decompensated Heart Failure: The SUBQ-HF Study." Total funding will be $1,812,000.

William E. Kraus of Cardiology has received an award from GlaxoSmithKline for a project entitled "GSK Parexel." Total funding will be $316,216.

Mitchell W. Krucoff of Cardiology has received an award from Abbott Vascular Devices for a project entitled "MDEpinNet: RAPID Phase II." Total funding will be $9,999.

Renato D. Lopes of Cardiology has received an award from Sanofi US for a project entitled "EFPEG Outcomes Study EFC14828." Total funding will be $4,495,662.

Ann M. Navar of Cardiology has received an award from Amgen, Inc. for a project entitled "Angiographic Predictors of Cardiovascular Events." Total funding will be $249,999.

Eric D. Peterson of Cardiology has received an award from Bayer HealthCare AG for a project entitled "DCRI Think Tank." Total funding will be $50,000.

Sunil V. Rao of Cardiology has received an award from AstraZeneca LP for a project entitled "AZ_CLiPPeR." Total funding will be $32,309.

Andrew Wang of Cardiology has received an award from MyoKardia, Inc. for a project entitled "EXPLORER-HCM (MYK-461-005)." Total funding will be $200,394.

Anna Mae Diehl of Gastroenterology has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "Duke University NASH Study: A Transcriptomics Analysis (DYNASTY Study)." Total funding will be $1,043,824.

Deborah A. Fisher of Gastroenterology has received an award from the Pentax Medical Company for a project entitled "Core Variable Assessment Towards a National Evaluation Program (CATNIP)." Total funding will be $9,800.

Cristina Gasparetto of Hematologic Malignancies and Cellular Therapy has received an award from AbbVie Inc. for a project entitled "A Phase 2, Open-Label, Multi-Center Study of Venetoclax in Combination with Carfilzomib and Dexamethasone in Subjects with Relapsed or Refractory Multiple Myeloma." Total funding will be $282,678.

Matthew S. McKinney of Hematologic Malignancies and Cellular Therapy has received an award from the Incyte Corporation for a project entitled "A Phase 2, Multicenter, Open-Label, Randomized Study Comparing INCB-50465, a PI3K8 Inhibitor, to Idelalisib in Relapsed or Refractory Follicular Lymphoma (CITADEL-203)." Total funding will be $235,760.

Matthew S. McKinney of Hematologic Malignancies and Cellular Therapy has received an award from The Bristol-Myers/Sanofi Pharmaceuticals, Inc. Partnership for a project entitled "Randomized, Open-label, Phase 3 Trial of Nivolumab plus Brentuximab vedotin versus Brentuximab vedotin alone Participatns with Relasped Refractory or Ineligible for Autologous Stem Cell Transplant." Total funding will be $461,346.

Murat O. Arcasoy of Hematology has received an award from the Incyte Corporation for a project entitled "An Open-Label Phase 2 Study of Itacitinib (INCB039110) in Combination with Low-Dose Ruxolitinib or Itacitinib Alone following Ruxolitinib in Subjects with Myelofibrosis." Total funding will be $178,024.

Thomas L. Ortel of Hematology has received an award from the Instrumentation Laboratory Company for a project entitled "LOO22511932 Rev 01 Hemosil Direct Thrombin Inhibitor (DTI) Assay with Dabigatran Calibrators and Controls." Total funding will be $21,871.

Thomas L. Ortel of Hematology has received an award from the Instrumentation Laboratory Company for a project entitled "L0022511991 Rev 01 Liquid Anti-Xa Assay with Rivaroxaban Calibrators and Controls Performance Evaluation Protocol on ACL TOP." Total funding will be $38,183.

Thomas L. Ortel of Hematology has received an award from the Instrumentation Laboratory Company for a project entitled "L0022511987 Rev 01 Hemosil, Liquid Anti-Xa Assay with Apixaban Calibrators and Controls Performance Evaluation and Fresh vs Frozen Stability Protocol on ACL. TOP 50 Family Series Analyzers." Total funding will be $39,782.

Andrew Armstrong of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase II Study of Navarixin (MK-7123) in Combination with Pembrolizumab (MK-3475) in Participants with Selected Advanced/Metastatic Solid Tumors." Total funding will be $939,510.

Jennifer Choe of Medical Oncology has received an award from Genmab A/S for a project entitled "Genmab GCT1021-01." Total funding will be $819,783.

Brent A. Hanks of Medical Oncology has received an award from Tempest Therapeutics for a project entitled "Investigating the Impact of TPST-1120 PPAR ї Inhibition on Anti-PD-1 Antibody Immunotherapy Efficacy in Pre-Clinical Melanoma Models." Total funding will be $248,805.

Brent A. Hanks of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "Investigating Biomarkers of Adaptive Resistance to Anti-PD-1 Antibody Immunotherapy in Melanoma." Total funding will be $543,716.

Shiaowen D. Hsu of Medical Oncology has received an award from Amgen, Inc. for a project entitled "Targeting KRAS (G12C) Mutant in Colorectal Cancer." Total funding will be $120,320.

Megan A. McNamara of Medical Oncology has received an award from The Prostate Cancer Clinical Trials Consortium for a project entitled "A Phase 1b/2 Study of Enzalutamide Plus CC-115 in Men with Castration-Resistant Prostate Cancer (CRPC); Sponsor ї Memorial Sloan Kettering Cancer Center." Total funding will be $155,491.

Michael A. Morse of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase II randomized study to evaluate the immunologic and antitumor activity of concurrent VRP-HER2 vaccination and Pembrolizumab for patients with advanced HER2-overexpressing breast cancer." Total funding will be $591,791.

John H. Strickler of Medical Oncology has received a sub-award through F. Hoffmann-La Roche Ltd for a project entitled "An Open-Label, Multicenter, Dose Escalation Phase I Study To Evaluate The Safety, Pharmacokinetics, And Therapeutic Activity Of Ro6958688, A Novel T Cell Bispecific Antibody That Targets The Human Carcinoembryonic Antigen (Cea) On Tumor Cells And Cd3." Total funding will be $868,558.

Alice L. Gray of Pulmonary, Allergy, and Critical Care Medicine has received an award from Vertex Pharmaceuticals Inc. for a project entitled "Efficacy and Safety of VX-659-102 Combination Therapy in Subjects iwth Cystic Fibrosis who are heterozygous for F508del Mutation & minimal function mutation." Total funding will be $70,359.

Lake D. Morrison of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "Novartis VAY736: A subject, investigator, and sponsor blinded randomized placebo controlled multicenter study to investigate VAY736 in patients with idiopathic pulmonary fibrosis." Total funding will be $278,708.

Timothy Scialla of Pulmonary, Allergy, and Critical Care Medicine has received an award from AstraZeneca AB for a project entitled "D5180C00009 SOURCE A multicentre randomized double blind placebo controlled Phase 3 study to evaluate the efficacy and safety of Tezepelumab." Total funding will be $191,658.