New funding awards - June 2020

Monday, July 20, 2020

Sponsored Research

Christopher Holley of Cardiology has received an award (1R01-GM135383-01) from the National Institutes of Health for a project entitled "SnoRNA-guided modifications of mRNA." Total funding will be $1,288,000.

Christopher Holley of Cardiology has received an award (3R01-GM135383-01S1) from the National Institutes of Health for a project entitled "SnoRNA-guided modifications of mRNA." Total funding will be $61,128.

Renato Lopes of Cardiology has received an award from the Bristoll Myers Squibb for a project entitled "CMS Linkage." Total funding will be $1.

Kristin Newby of Cardiology has received an award from the NC DHHS for a project entitled "MURDOCK NCDHHS COVID-19 Prevalence Study." Total funding will be $200,000.

Jonathan Piccini of Cardiology has received a sub-award () through the University of British Columbia for a project entitled "ORBIT AF." Total funding will be $56,164.

David D'Alessio of Endocrinology has received a sub-award (1P30-DK124723-01) through the Wake Forest University School Of Medicine for a project entitled "Admin Core." Total funding will be $155,233.

Rodger Liddle of Gastroenterology has received an award (1R01-DK125308-01) from the National Institutes of Health for a project entitled "Metabolic regulation of pancreatitis." Total funding will be $1,449,000.

Ayako Suzuki of Gastroenterology has received an award (75F40120P00063) from the Food and Drug Administration for a project entitled "Specialized Consultation: Technical Expert in Predictive Toxicology." Total funding will be $10,665.

Ebony Boulware of General Internal Medicine has received an award (3UL1- TR002553-03S2) from the National Institutes of Health for a project entitled "Support for QA/QC for Prior Approval Process." Total funding will be $623,502.

Anthony Sung of Hematologic Malignancies and Cellular Therapy has received an award (1R01-AG066719-01) from the National Institutes of Health for a project entitled "Home-based Autologous Hematopoietic Stem Cell Transplantation to Improve Outcomes and Decrease Costs." Total funding will be $3,164,089.

Anthony Sung of Hematologic Malignancies and Cellular Therapy has received an award (1R01-HL151365-01) from the National Institutes of Health for a project entitled "A Randomized Phase 2 Trial to Evaluate Prebiotic Intervention in Allogeneic Hematopoietic Stem Cell Transplantation." Total funding will be $1,811,250.

Ammon Fager of Hematology has received an award from the Hemostasis & Thrombosis Research Society for a project entitled "Understanding and Enhancing the Therapeutic Efficacy of Factor VIIa for Emergency Hemostasis." Total funding will be $162,000.

Marilyn Telen of Hematology has received a sub-award (1UG3-HL143192-01A1) through the University of Pittsburgh for a project entitled "Sickle Cell Disease and CardiovAscular Risk - Red cell Exchange Trial (SCD-CARRE)." Total funding will be $1.

Ephraim Tsalik of Infectious Diseases has received an award from the Ann & Robert H. Lurie Children's Hospital of Chicago for a project entitled "Transcriptomics and Metabolomics to Improve Risk Stratification in Pediatric Pneumonia." Total funding will be $62,767.

John Strickler of Medical Oncology has received an award from the Experimental Drug Development Centre for a project entitled "A Phase 1A/B Study To Evaluate The Safety And Tolerability Of ETC-1922159 In Advanced Solid Tumours." Total funding will be $720,924.

Patrick Pun of Nephrology has received a sub-award (1R01-HL152034-01) through the University of North Carolina - Chapel Hill for a project entitled "QT prolonging medications and sudden cardiac death among individuals on hemodialysis." Total funding will be $60,652.

Tomokazu Souma of Nephrology has received an award (R01-DK123097-01A1) from the National Institutes of Health for a project entitled "R01: Targeting Renal Tubular Epithelial Progenitors in AKI to CKD transition." Total funding will be $2,203,357.

Jennifer Ingram of Pulmonary has received an award (1R21-AI146761-01A1) from the National Institutes of Health for a project entitled "Matrix Metalloproteinase-19 as a Mediator of Airway Fibrosis in Obese Allergic Asthma." Total funding will be $438,480.

Scott Palmer of Pulmonary has received an award (1R21-TR003037-01A1) from the National Institutes of Health for a project entitled "Proof of Concept Treatment Interventions in a Rodent Model of the Rare Disease Bronchiolitis Obliterans." Total funding will be $442,750.

Scott Shofer of Pulmonary has received a sub-award () through the Institute for Medical Research, Inc. for a project entitled "IMR PSA: Wendy Curry." Total funding will be $74,253.

Robert Tighe of Pulmonary has received a sub-award (7R01-ES028829-03) through the Ohio State University for a project entitled "Novel role for CD163 in ozone induced alterations of pulmonary immunity." Total funding will be $201,952.

Megan Clowse of Rheumatology has received a sub-award (2U19-AI110483-06) through the Emory University for a project entitled "A Phase 2, Double-blind, Randomized, Placebo-controlled Milticenter Study to Evaluate Efficacy, Safety, and Tolerability of JBT-101 in Systemic Lupus Erythematosus." Total funding will be $1.

Kim Huffman of Rheumatology has received an award (1R21-AR076663-01) from the National Institutes of Health for a project entitled "Weight loss and exercise to improve rheumatoid arthritis cardiovascular risk." Total funding will be $566,720.

Industry-sponsored Clinical Trials

Sana Al-Khatib of Cardiology has received an award from Boston Scientific Corporation for a project entitled "BD-023: Implantable Cardioverter Defibrillator Use Among Patients with Hypertrophic Cardiomyopathy." Total funding will be $92,853.

Brett Atwater of Cardiology has received a sub-award (U01-FD006292-) through Medical Device Innovation Consortium for a project entitled "REMOTE HF-ACTION." Total funding will be $302,934.

Michael Blazing of Cardiology has received an award from Merck for a project entitled "IMPROVE-IT Secondary Manuscripts." Total funding will be $1.

Gary Felker of Cardiology has received an award from Bayer Corporation for a project entitled "Characterization of Patients with Heart Failure and Patients with Vascular Disease and Atrial Fibrillation in Duke University Health System Data." Total funding will be $397,718.

Michel Khouri of Cardiology has received an award from Boston Scientific Corporation for a project entitled "BD-024: Assessing Pacing Strategies in Cardiac Amyloidosis." Total funding will be $59,519.

Robert Mentz of Cardiology has received an award from Boston Scientific Corporation for a project entitled "BD-022: Duke HeartLogic LVAD." Total funding will be $53,326.

Manesh Patel of Cardiology has received an award from Idorsia Pharmaceuticals Ltd for a project entitled "ID-076A301; SOS-AMI; Multi-center, double-blind, randomized, placebo-controlled, parallel-group study to evaluate the efficacy and safety of subcutaneous self-administration of selatogrel for preventi." Total funding will be $2,437,295.

Manesh Patel of Cardiology has received an award from Bayer Inc. for a project entitled "Characterization of Patients with Heart Failure and Patients with Vascular Disease and Atrial Fibrillation in PCORnet Data." Total funding will be $536,509.

Svati Shah of Cardiology has received an award from Eli Lilly and Company for a project entitled "Exploration of Cardiovascular Phenotypes in the CATHGEN Study (the "Project")." Total funding will be $125,000.

Andrew Wang of Cardiology has received an award from Cytokinetics, Inc. for a project entitled "This is a Randomized, Double-blind, Placebo-controlled, Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK­3773274 in Adults with Symptomatic Hypertrophic Cardiomyopathy and Left Ventricular Outflow." Total funding will be $746,962.

Tracy Wang of Cardiology has received an award from American College of Cardiology Foundation for a project entitled "Cath PCI Registry 2020 (Amendment 29)." Total funding will be $289,420.

Manal Abdelmalek of Gastroenterology has received an award from Madrigal Pharmaceuticals, Inc. for a project entitled "A 52-Week, Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Patients with Non-alcoholic Fatty Liver Disease (NAFLD) (MAESTRO-NAFLD-1)." Total funding will be $486,376.

Jatin Roper of Gastroenterology has received an award from Fractyl Laboratories, Inc. for a project entitled "Viral transduction of intestinal epithelium in the colon of mice mediated by sub-mucosal injection." Total funding will be $48,096.

Cathleen Colon-Emeric of Geriatrics has received an award from UCB Biopharma SPRL for a project entitled "UCB Osteoporosis." Total funding will be $373,140.

Thomas Ortel of Hematology has received an award from Diagnostica Stago for a project entitled "Stago - STA-NeoPTimal 5ml and 10 ml Single Site Precision Study." Total funding will be $43,238.

Thomas Ortel of Hematology has received an award from Diagnostica Stago for a project entitled "Stago - STA-NeoPTimal 5ml and 10m: Multisite Precision Study." Total funding will be $22,836.

Marilyn Telen of Hematology has received an award from CSL Behring LLC for a project entitled "Biologic Assessment and RBC Functional Health Score for Evaluation of Sickle Cell Disease Activity and Response to Therapy (SC-DART)." Total funding will be $250,000.

Vance Fowler of Infectious Diseases has received a sub-award (HHSO100201600002C) through Basilea Pharmaceutica for a project entitled "CEC Activities for BPR-CS-009 Ceftobiprole medocaril - WO2 - Amendment 1." Total funding will be $6,207.

Jennifer Choe of Medical Oncology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "RGN-1901." Total funding will be $168,624.

Jeffrey Clarke of Medical Oncology has received an award from Achilles Therapeutics for a project entitled "Prospective collection of donor tissue and blood or leukapheresis product from patients with solid tumours to enable development of methods for the manufacturing of clonal neoantigen T cell products (cNeT).." Total funding will be $118,668.

Daniel George of Medical Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "An Open-label, Multi-drug, Multi-center Phase II Combination Study of  AZD4635 in Patients with Prostate Cancer." Total funding will be $488,210.

Michael Harrison of Medical Oncology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "A randomized, open-label, multicenter, Phase 2b study to evaluate physical function, including balance and daily activity, in participants with castration-resistant prostate  cancer treated with darolutamide or enzalutamide." Total funding will be $93,642.

Shiaowen Hsu of Medical Oncology has received an award from Xilis, Inc. for a project entitled "Development of an Organoid/MicroOrganoid Biobank with matching TILs (Tumor Infiltrating Lymphocytes) to Correlate Response to Therapy." Total funding will be $161,000.

Niharika Mettu of Medical Oncology has received an award from Amphivena Therapeutics for a project entitled "AMV564-301." Total funding will be $423,883.

Richard Riedel of Medical Oncology has received an award from GlaxoSmithKline for a project entitled "Long Term Follow-Up of Participants Exposed to GSK3377794 (NYESO- 1c259 T), a Genetically Engineered NY-ESO-1 Specific T Cell Receptor." Total funding will be $284,735.

Sarah Sammons of Medical Oncology has received an award from Sermonix Pharmaceuticals for a project entitled "Sermonix SMX 18-001." Total funding will be $131,343.

John Strickler of Medical Oncology has received an award from Gossamer Bio for a project entitled "Investigational drug GB1275 in combo with standard therapy for certain metastatic GI cancers." Total funding will be $658,273.

Opeyemi Olabisi of Nephrology has received an award from Vertex Pharmaceuticals Inc. for a project entitled "A Phase 2a, Open-label, Single-arm, 2-Part Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VX¿147 in Adults With APOL1-dependent Focal Segmental Glomerulosclerosis." Total funding will be $324,443.