New funding awards - June 2021

Tuesday, July 27, 2021

Sponsored Research 

Jennifer Rymer of Cardiology has received an award from the Vascular Cures for a project entitled "Validating the Peripheral Artery Questionnaire and Vascular Quality of Life Questionnaire in a Population of Patients with Chronic Limb Threatening Ischemia." Total funding will be $50,000.

Svati Shah of Cardiology has received an award (1R21-AI158786-01A1) from the National Institutes of Health for a project entitled "Inflammatory and Metabolic Biomarkers in Cardiovascular Complications with SARS-CoV-2." Total funding will be $456,380. 

Sreekanth Vemulapalli of Cardiology has received a sub-award (U01-FD006292-) through the Yale University for a project entitled "Impact of Apple Watch on Quality of Life in Patients with Atrial Fibrillation." Total funding will be $222,450.

Eleanor C. Semmes (Mentor: Christopher Kontos) of Cardiology has received an award from the Triangle Community Foundation for a project entitled "Gertrude B. Elion Mentored Medical Student Award." Total funding will be $10,000.

Laura R. Stilwell (Mentor: Christopher Kontos) of Cardiology has received an award from the Triangle Community Foundation for a project entitled "Gertrude B. Elion Mentored Medical Student Award." Total funding will be $10,000.

Carolyn V. Diaz (Mentor: Christopher Kontos) of Cardiology has received an award from the Triangle Community Foundation for a project entitled "Gertrude B. Elion Mentored Medical Student Award." Total funding will be $10,000.

Rebecca A. Gibson (Mentor: Christopher Kontos) of Cardiology has received an award from the Triangle Community Foundation for a project entitled "Gertrude B. Elion Mentored Medical Student Award." Total funding will be $10,000.

Kuo Du (Mentor: Anna Mae Diehl) of Gastroenterology has received an award from the American Association for the Study of Liver Diseases for a project entitled "Hippo-Yap Pathway, Ferroptosis of Hepatic Stellate Cells and Liver Fibrosis." Total funding will be $300,000.

Leigh Boulware of General Internal Medicine has received an award (1U01-DK127918-01) from the National Institutes of Health for a project entitled "Health system outreach to eliminate disparities in living kidney transplants." Total funding will be $5,926,967.

Leigh Boulware of General Internal Medicine has received an award (3UL1-TR002553-04S2) from the National Institutes of Health for a project entitled "Stress, Coping and Asthma in Black Adults." Total funding will be $422,465.

Grace Lee of Hematology has received an award from the Hemostasis & Thrombosis Research Society for a project entitled "Neutrophil activation responses to platelet factor 4/heparin immune complexes." Total funding will be $8,000.

Chris Woods of Infectious Diseases has received a sub-award (W911QY-19-9-0006) through the Henry M. Jackson Foundation for a project entitled "Prophylaxis and Treatment of COVID19 ¿ Adaptive Platform Trial (PROTECT-APT)." Total funding will be $2,087,989.

Arthur Baker of Infectious Diseases has received an award (1K08-AI163462-01) from the National Institutes of Health for a project entitled "Combined Use of Statistical Process Control and Whole Genome Sequencing to Detect and Investigate Nontuberculous Mycobacterial Clusters and Outbreaks (K08)." Total funding will be $942,317.

Deverick Anderson of Infectious Diseases has received an award (1U54-CK000616-01) from the Centers for Disease Control and Prevention for a project entitled "CORE COLLABORATIVE - Improving patient outcomes through the Duke-UNC Prevention Epicenters Program." Total funding will be $545,228.

Deverick Anderson of Infectious Diseases has received an award (1U54-CK000616-01) from the Centers for Disease Control and Prevention for a project entitled "LARGE COLLABORATIVE - A non-inferiority cluster randomized trial with crossover design to assess the need for contact precautions for endemic MRSA and VRE." Total funding has yet to be determined.

Deverick Anderson of Infectious Diseases has received an award (1U54-CK000616-01) from the Centers for Disease Control and Prevention for a project entitled "SMALL COLLABORATIVE - Assessing the frequency and type of endogenous contamination of surgical wounds using metagenomic sequencing." Total funding has yet to be determined.

Rebekah Moehring of Infectious Diseases has received an award (1U54-CK000616-01) from the Centers for Disease Control and Prevention for a project entitled "MEDIUM COLLABORATIVE - Feasibility and Utility of robust antibiotic use risk-adjustment in Antimicrobial Stewardship Program Assessments, a part of Deverick J. Anderson's project entitled "Duke-UNC Prevention Epicenter Program for Protecting Patients from Infections, Antibiotics Resistance and Other Adverse Events."  Total funding has yet to be determined.

Chris Woods of Infectious Diseases has received an award from the Institute for Medical Research, Inc. for a project entitled "IMR PSA: Deb Murray (CLOVER)." Total funding will be $52,656.

Thuy Le of Infectious Diseases has received an award (1R21-AI162367-01A1) from the National Institutes of Health for a project entitled "Mapping of the IgM and IgG antibody responses to Talaromyces marneffei infection in mice and humans - Deciphering acute from reactivated or latent infections (R21)." Total funding will be $433,600.

Brent Hanks of Medical Oncology has received an award (1 R37 -CA249085-01S1) from the National Institutes of Health for a project entitled "Exploration of Tumor-Intrinsic NLRP3 Signaling Regulators." Total funding will be $326,155.

James Isaacs (Mentor: Neal Ready) of Medical Oncology has received an award from the Lung Cancer Initiative of North Carolina for a project entitled "Evaluating the Impact of PCSK9 on the Composition of the Tumor-Immune Microenvironment and Treatment Response to Immune Checkpoint Blockade in NSCLC." Total funding will be $25,000.

Patrick Pun of Nephrology has received a sub-award () through the New York University School of Medicine for a project entitled "Association Between ECG data obtained via the Medtronic Reveal LINQ device and Real-Time Blood Chemistry Values: RADAR Ancillary Study Proposal." Total funding will be $21,041.

Deepshikha Ashana of Pulmonary has received an award from the National Palliative Care Research Center for a project entitled "Traumatic Life Events Among Family Members of ICU Patients." Total funding will be $198,000.

Kamran Mahmood of Pulmonary has received an award (W81XWH2010280 LC190500) from the Department of Defense for a project entitled "Cell-Free DNA for Diagnosis of Malignancy, Genetic Mutations and Prognosis in Lung Cancer Related Pleural Effusions." Total funding will be $161,000.

Loretta Que of Pulmonary has received a sub-award () through the American Lung Association for a project entitled "ALA LHC Boehringer Ingelheim Supplement." Total funding will be $7,082.

Ankoor Shah of Rheumatology has received a sub-award (5UM1-AI1095656-08) through the Benaroya Research Institute at Virginia Mason for a project entitled "Evaluation of Brentuximab Vedotin for Diffuse Cutaneous Systemic Sclerosis: A Phase I/II Multicenter, Randomized, Double-Blinded Safety Study - Cost Reimbursable Code." Total funding will be $26,315.
 

Industry-Sponsored Clinical Trials

Renato Lopes of Cardiology has received an award from Bristol-Myers Squibb Company for a project entitled "AUGUSTUS_Extension." Total funding will be $887,405.

Melissa Daubert of Cardiology has received an award from 4D Molecular Therapeutics for a project entitled "4D MT - 4D-310_Follow Up - Taiwan." Total funding will be $860,914.

Renato Lopes of Cardiology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "Regeneron 20118." Total funding will be $208,662.

Andrew Muir of Gastroenterology has received an award from CymaBay Therapeutics for a project entitled "ASSURE: An Open Label Long-Term Study to Evaluate the Safety and Tolerability of Seladelpar in Subjects with Primary Biliary Cholangitis (PBC)." Total funding will be $185,962.

Taewoong Choi of Hematologic Malignancies and Cellular Therapy has received an award from Janssen Research & Development, LLC for a project entitled "A Phase 3 Randomized Study Comparing JNJ-68284528, a Chimeric Antigen Receptor T cell (CAR-T) Therapy Directed Against BCMA, versus Pomalidomide, Bortezomib and Dexamethasone (PVd) or Daratumumab, Pomalidomide and Dexamethasone (DPd)." Total funding will be $718,455.

Cristiana Costa Chase of Hematologic Malignancies and Cellular Therapy has received an award from Caelum BioSciences, Inc for a project entitled "Phase 3, Double-Blind, Multicenter Study to Evaluate the Efficacy and Safety of CAEL-101 302 py in Treatment Naive Patients with Stage IIIa or IIIb AL Cardiac." Total funding will be $462,207.

Cristiana Costa Chase of Hematologic Malignancies and Cellular Therapy has received an award from Caelum BioSciences, Inc for a project entitled "Caleium Pharm:Ph3 CAEL-101-301 AL Amyloidosis." Total funding will be $462,207.

Lindsay Rein of Hematologic Malignancies and Cellular Therapy has received an award from Incyte Corporation for a project entitled "Inhibitor Parsaclisib Plus Ruxolitinib in Participants With Myelofibrosis Who Have Suboptimal Response to Ruxolitinib." Total funding will be $440,267.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from SYROS PHARMACEUTICALS for a project entitled "SY-1425 in Combination with Venetoclax and Azacitidine in Adult Patients with RARA-positive, Previously Untreated AML Who Are Ineligible for Standard Induction Therapy." Total funding will be $1,489,752.

Nelson Chao of Hematologic Malignancies and Cellular Therapy has received an award from Omeros Corporation for a project entitled "Experimental pharmacology study in mice-Narsoplimab (OMS721)." Total funding will be $160,754.

Mitchell Horwitz of Hematologic Malignancies and Cellular Therapy has received an award from Allovir, Inc. for a project entitled "ALVR106 in Treatment of High-Risk Patients with Respiratory Viral Infections After HSCT." Total funding will be $196,130.

Nirmish Shah of Hematology has received an award from Global Blood Therapeutics, Inc. for a project entitled "GBT2104-131 A Randomized, Double-blind, Placebo-controlled, Multicenter Study to Assess the Safety and Efficacy of Inclacumab in Participants with Sickle Cell Disease (SCD) Experiencing Vaso-occlusive Crisis (VOCs)." Total funding will be $119,731.

Mehri McKellar of Infectious Diseases has received an award from ViiV Healthcare for a project entitled "Ph 2a multicenter, randomized, open label, two part adaptive design study to evaluate the antiviral effect safety and tolerability of GSK 3810109A, an HIV-1 specific broadly neutralizing human monoclonal antibody in antiretroviral naive HIV-1 adults." Total funding will be $217,191.

Chris Woods of Infectious Diseases has received an award from Abbott Rapid Diagnostics for a project entitled "Abbott Rapid Diagnostics Jena GmbH - CLDG-0511, Clinical Evaluation of the BinaxNOW COVID-19 IgG Rapid Test Device and the BinaxNOW COVID-19 Antibody Self Test Clinical Study Protocol (Pro00053807)." Total funding will be $119,081.

Jeffrey Clarke of Medical Oncology has received an award from Achilles Therapeutics for a project entitled "An Open-Label, Multi-Center Phase I/IIa Study Evaluating the Safety and Clinical Activity of Neoantigen Reactive T cells in Patients with Advanced Non-Small Cell Lung Cancer (CHIRON)." Total funding will be $637,192.

Niharika Mettu of Medical Oncology has received an award from Mereo BioPharma Group for a project entitled "A Phase 1b/2 Open-Label Study of the Efficacy and Safety of Etigilimab (MPH313) Administered in Combination with Nivolumab to Subjects with Locally Advanced or Metastatic Solid Tumors." Total funding will be $959,007.

Andrew Armstrong of Medical Oncology has received an award from FORMA Therapeutics, Inc. for a project entitled "under protocol number 7051-ONC-101 entitled "A Phase 1 Study of FT-7051 in Men with Metastatic Castration-Resistant Prostate Cancer" (as it may be amended from time to time by Sponsor, the "Protocol"; the performance of the Protocol at all sites is." Total funding will be $341,851.

Loretta Que of Pulmonary has received an award from ProspAir,LLC for a project entitled "Peep Mask study." Total funding will be $25,610.

Rebecca Sadun of Rheumatology has received an award from Childhood Arthritis & Rheumatology Research Alliance, Inc. for a project entitled "Identifying Cross-Registry Commonalities to Facilitate International Pediatric Lupus Research." Total funding will be $16,350.