New funding awards - May 2019

Tuesday, June 11, 2019

Sponsored Research

Sana Al-Khatib of Cardiology has received a sub-award (5R34-HL132031-02 REVISED) through the University of Pittsburgh for a project entitled "Cardiac Resychronization in the Elderly: Piloting Pacemaker vs. Defibrilator Therapy." Total funding will be $1.

Pamela Douglas of Cardiology has received a sub-award (1U01-HL146382-01) through the Boston University for a project entitled "RURAL: Risk Underlying Rural Areas Longitudinal Cohort Study." Total funding will be $18,785.

Jamie L. Courtland (Mentor: Christopher Kontos) of Cardiology has received an award from the Triangle Community Foundation for a project entitled "Gertrude B. Elion Mentored Medical Student Award." Total funding will be $10,000.

Richard Krasuski of Cardiology has received an award from the Adult Congenital Heart Association for a project entitled "Peer Coaching Adaptive Self-Management Interventions for Young Adults with Congenital Heart Disease (CHASM IN ACHD)." Total funding will be $32,500.

Francis Miller of Cardiology has received an award from the American Heart Association for a project entitled "Extracellular Histones and Sepsis-induced Cardiomyopathy." Total funding will be $100,000.

Sudarshan Rajagopal of Cardiology has received an award from the American Heart Association for a project entitled "Single Cell Profiling and Disease Modeling of CTEPH." Total funding will be $100,000.

Sunil Rao of Cardiology has received an award from the American College of Cardiology Foundation for a project entitled "The Duke Renal Impairment Program (DRIP) Initiative." Total funding will be $83,681.

Matthew Roe of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Aspirin Dosing: A Patient-centric Trial Assessing Benefits and Long-term Effectiveness (ADAPTABLE)." Total funding will be $110,552.

Cris Slentz of Cardiology has received a sub-award (1R01-HL146462-01) through the University of South Carolina for a project entitled "Molecular Basis of Exercise-induced Changes in HDL Function." Total funding will be $18,428.

Matthew Hirschey of Endocrinology has received an award (3R01-AG045351-05S1) from the National Institutes of Health for a project entitled "Studies on the Mechanisms by which SIRT5 Regulates Aging and Disease." Total funding will be $160,167.

Cynthia Moylan of Gastroenterology has received a sub-award (1R21-CA227023-01A1) through the North Carolina State University for a project entitled "Hepatocellular Carcinoma, Epigenetics and Cadmium Exposure." Total funding will be $74,122.

Christopher Bowling of Geriatrics has received a sub-award (1R01-AG061179-01) through the Emory University for a project entitled "Burden, correlates, and outcomes of poor cognitive and physical functioning in the lupus population." Total funding will be $34,305.

John Perfect of Infectious Diseases has received a sub-award (2U19-AI110818-06) through the Broad Institute for a project entitled "Advancing Genomic Technologies to Combat Infectious Disease: Mapping Dynamics within Single Cells, Individual Hosts, and Global Populations." Total funding will be $55,000.

Chris Woods of Infectious Diseases has received a sub-award (140D6319C0023) through the Research Triangle Institute International for a project entitled "Human-Based Sensor System for Presymptomatic Biological Exposure Detection." Total funding will be $3,615,408.

Chris Woods of Infectious Diseases has received a sub-award () through the Institute for Medical Research, Inc. for a project entitled "IMR PSA: Sara Hoffman (SWITCH)." Total funding will be $24,575.

Chris Woods of Infectious Diseases has received a sub-award () through the Institute for Medical Research, Inc. for a project entitled "IMR PSA: Mark Sprenz." Total funding will be $3,691.

James Abbruzzese of Medical Oncology has received an award (3UM1-CA186704-05S1) from the National Institutes of Health for a project entitled "Administrative Supplements to Existing NIH Grants and Cooperative Agreements (Parent Admin Supp Clinical Trial Optional)." Total funding will be $775,167.

Carey Anders of Medical Oncology has received an award from the Conquer Cancer Foundation for a project entitled "Molecular Dissection and Immune Characterization of Breast Cancer Brain Metastases to Predict Outcomes and Reveal Novel Therapeutic Strategies." Total funding will be $66,665.

Xunrong Luo of Nephrology has received a sub-award (5R01-EB009910-09) through the Regents of the University of Michigan for a project entitled "Protein-Releasing Microporous Scaffolds for Cell Replacement Therapy." Total funding will be $503,902.

Xunrong Luo of Nephrology has received a sub-award (3-SRA-2016-259-S-B) through the Northwestern University for a project entitled "Tolerance for Xenogeneic Islet Cell Transplantation in Non-human Primates." Total funding will be $326,809.

Xunrong Luo of Nephrology has received a sub-award (5U01-AI120130-04 Revised) through the Regents of the University of Minnesota for a project entitled "Pig-to-Monkey Islet Xenotransplantation." Total funding will be $53,219.

Julia Scialla of Nephrology has received a sub-award (5U24-DK115255-02) through the Augusta University for a project entitled "Urine TCA-Cycle Organic Anions in Diabetic Kidney Disease." Total funding will be $99,435.

Carolyn Baloh (Mentor: Patricia Lugar) of Pulmonary has received an award from the Immune Deficiency Foundation for a project entitled "Clinical indicators for early bone loss in Common Variable Immunodeficiency." Total funding will be $35,000.

Loretta Que of Pulmonary has received an award from the American Lung Association for a project entitled "Asthma BMI Baseline Study (ABBS)." Total funding will be $266.

Laurie Snyder of Pulmonary has received a sub-award (GODFRE18QI0) through the Dartmouth College for a project entitled "CF Lung Transplant Transition LLC Phase 2 Program Extension Post NACFC October 2018 through May 30, 2019." Total funding will be $12,960.

Industry-sponsored Clinical Trials

Adrian Hernandez of Cardiology has received an award from Daiichi Sankyo Inc for a project entitled "ARAMIS Registry (Daiichi Sankyo, Inc.)." Total funding will be $2,637,189.

William Herzog of Cardiology has received an award from Novo Nordisk, Inc. for a project entitled "Semaglutide Effects on Cardiovascular Outcomes in People with Overweight or Obesity." Total funding will be $625,570.

Robert Mentz of Cardiology has received an award from AstraZeneca LP for a project entitled "Uric Acid Lowering Analyses in Duke University Health System and RELAX-HF trial." Total funding will be $128,936.

Jonathan Piccini of Cardiology has received an award from American Heart Association for a project entitled "Get With The Guidelines SOW #20." Total funding will be $181,650.

Jonathan Piccini of Cardiology has received an award from St. Jude Medical Inc. for a project entitled "Impact of AF Burden on Cardiovascular Events." Total funding will be $149,969.

Tracy Wang of Cardiology has received an award from American College of Cardiology Foundation for a project entitled "Chest Pain MI Registry - Alex F. Manuscript CO#18." Total funding will be $58,225.

Tracy Wang of Cardiology has received an award from American College of Cardiology Foundation for a project entitled "Chest Pain MI Registry - Patient Navigator Manuscript CO#19." Total funding will be $5,346.

Manal Abdelmalek of Gastroenterology has received an award from Akcea Therapeutics for a project entitled "Akcea ISIS 703802-CS2." Total funding will be $15,999.

Andrew Muir of Gastroenterology has received an award from CymaBay Therapeutics for a project entitled "CymaBay CB8025-31735." Total funding will be $115,746.

Jane Onken of Gastroenterology has received an award from Seres Therapeutics, Inc for a project entitled "DG29 SERES." Total funding will be $131,451.

Ammon Fager of Hematology has received an award from Otello Medical, Inc. for a project entitled "PC-ChFVIIa Proof of Concept Studies." Total funding will be $114,966.

Manal Abdelmalek of Infectious Diseases has received an award from ENYO Pharma SA for a project entitled "A Phase 2a, Randomized, Double-Blind, Multicenter, Placebo-Controlled Study to Assess the Safety, Tolerability, Pharmacokinetics, and Efficacy of EYP001a in Patients With Nonalcoholic Steatohepatitis." Total funding will be $140,960.

Gregory Gray of Infectious Diseases has received a sub-award (N6264518D5058-N62645) through Vysnova Partners, Inc. for a project entitled "Targeted Surveillance for H7N9 Avian Influenza in Northern Vietnam." Total funding will be $95,725.

John Perfect of Infectious Diseases has received a sub-award (1R01-AI144091-01) through Linnaeus Bioscience Inc. for a project entitled "Development of a new class of antifungals effective against Cryptococcus." Total funding will be $241,300.

Andrew Armstrong of Medical Oncology has received an award from AstraZeneca AB for a project entitled "Study title: A Randomized, Double-blind, Placebo-controlled, Multicenter Phase III Study of Olaparib Plus Abiraterone Relative to Placebo Plus Abiraterone as First-line Therapy in Men with Metastatic Castration-resistant Prostate Cancer." Total funding will be $130,179.

Jeffrey Crawford of Medical Oncology has received an award from Helsinn Healthcare S.A. for a project entitled "PHASE 3, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, MULTICENTER STUDY TO EVALUATE THE EFFICACY AND SAFETY OF ANAMORELIN HCL." Total funding will be $105,804.

Andrew Nixon of Medical Oncology has received a sub-award (HHSN261200800001E) through Leidos Biomedical Research, Inc. for a project entitled "Identification and validation of plasma-based protein biomarkers for cediranib and olaparib." Total funding will be $224,662.

Richard Riedel of Medical Oncology has received an award from SpringWorks Therapeutics for a project entitled "A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Trial of Nirogacestat Versus Placebo in Adult Patients With Progressing Desmoid Tumors/Aggressive Fibromatosis (DT/AF)." Total funding will be $314,292.

Patrick Pun of Nephrology has received an award from Hope Pharmaceuticals Inc. for a project entitled "A Phase 3, Intravenous Sodium Thiosulfate for Acute Calciphylaxis Treatment: A Multicenter, Randomized, Double-blind, Placebo-controlled, Clinical Trial." Total funding will be $268,295.

Stephen Bergin of Pulmonary has received an award from Karius, Inc. for a project entitled "Pneumonia LOI." Total funding will be $792,803.

George Cheng of Pulmonary has received an award from Concordia Laboratories Inc. for a project entitled "PDT Registry." Total funding will be $111,000.

Omar Mohamedaly of Pulmonary has received a sub-award (5R44-HL130189-03) through Path Bioanalytics, Inc. for a project entitled "Human tissue repository for personalized assay development." Total funding will be $8,644.

Lake Morrison of Pulmonary has received an award from Galapagos NV for a project entitled "GLPG1690-CL-304 A Phase 3 randomized double blind parallel group, placebo controlled multicenter study to evaluate efficacy and safety of 2 doses of GLPG1690 in addition to local standard of care." Total funding will be $222,921.

Megan Clowse of Rheumatology has received an award from GlaxoSmithKline for a project entitled "Hop Step II." Total funding will be $347,071.