New funding awards - May 2021

Monday, June 7, 2021

Sponsored Research 

Jonathan Piccini of Cardiology has received an award from American Heart Association for a project entitled "GWTG 2021 Budget." Total funding will be $864,445.

Jie Wang of Hematologic Malignancies and Cellular Therapy has received an award from Daiichi Sankyo Inc for a project entitled ": A PHASE 1 MULTIPLE ASCENDING DOSE STUDY OF DS-3201B IN SUBJECTS WITH LYMPHOMAS." Total funding will be $743,374.

Lindsay Rein of Hematologic Malignancies and Cellular Therapy has received an award from Blueprint Medicines Corporation for a project entitled "Randomized, Double-Blind, Placebo-Controlled Ph2 BLU-285 in Indolent and Smoldering Systemic." Total funding will be $593,635.

Tian Zhang of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "A Phase 1 Study to Evaluate the Safety, Pharmacokinetics, and Pharmacodynamics of Escalating Doses of PF-06940434 in Patients with Advanced or Metastatic Solid Tumors." Total funding will be $424,975.

Marat Fudim of Cardiology has received an award from Axon Therapies, Inc. for a project entitled "Endovascular Ablation of the Right Greater Splanchnic Nerve in Subjects Having Heart Failure with Preserved Ejection Fraction: Randomized Controlled Feasibility Trial." Total funding will be $372,543.

Michael Morse of Medical Oncology has received an award from AMAL Therapeutics S.A. for a project entitled "An Open-Label, Multicenter, Non-Randomized, Dose-Confirmation and Cohort-Expansion Phase 1b Study to Evaluate the Safety, Tolerability, and Anti-Tumor Activity of ATP128, with or without BI 754091, in Patients with Stage IV Colorectal Cancer." Total funding will be $277,623.

Neal Ready of Medical Oncology has received an award from Bristol-Myers Squibb Company for a project entitled "BMS 050." Total funding will be $268,568.

Mitchell Horwitz of Hematologic Malignancies and Cellular Therapy has received an award from Alexion Pharmaceuticals, Inc. for a project entitled "A Phase 3, Open-label, Randomized, Multicenter Study of Ravulizumab in Adult and Adolescent Participants who have Thrombotic Microangiopathy (TMA) after Hematopoietic Stem Cell Transplant (HSCT)." Total funding will be $253,793.

Arthur Baker of Infectious Diseases has received an award from Insmed for a project entitled "ENCORE-A ransomized, double-blind, placebo-controlled, active comparator, multicenter study to evaluate the efficacy and safety of an Amikacin Liposome Inhalation Suspension (ALIS)-based regimen in adult subjects with new diagnosed nontuberculour." Total funding will be $231,237.

Carlos Decastro of Hematologic Malignancies and Cellular Therapy has received an award from Alexion Pharmaceuticals, Inc. for a project entitled "A Phase 3 Study of Danicopan (ALXN2040) as Add-on Therapy to a C5 Inhibitor (Eculizumab or Ravulizumab) in Patients with Paroxysmal." Total funding will be $195,895.

Niharika Mettu of Medical Oncology has received an award from SYROS PHARMACEUTICALS for a project entitled "A Phase 1 Study of SY-5609, an Oral, Selective CDK7 Inhibitor, in Adult Patients With Select Advanced Solid Tumors." Total funding will be $195,357.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from SYROS PHARMACEUTICALS for a project entitled "A Randomized, Double-blind, Placebo-controlled Phase 3 Study of SY-1425 Plus Azacitidine Versus Placebo Plus Azacitidine in Newly Diagnosed, RARA-positive Adult Patients with Higher-risk Myelodysplastic Syndrome (SY-1425-301)." Total funding will be $188,529.

Arthur Baker of Infectious Diseases has received an award from Insmed for a project entitled "ARISE-A randomized, double-blind, placebo-controlled, active comparator, multicenter study to validate patient-reported outcome instruments in adult subjects with newly diagnosed nontuberculous mycobacterial (NTM) lung infection caused by MAC.." Total funding will be $181,828.

Jingquan Jia of Medical Oncology has received an award from Genentech, Inc. for a project entitled "GO42661 A Phase II, Randomized, Double-Blind, Placebo-Controlled Study of Atezolizumab With or Without Bevacizumab in Combination With Cisplatin Plus Gemcitabine in Patients With Untreated, Advanced Biliary Tract Cancer." Total funding will be $171,990.

Jeffrey Clarke of Medical Oncology has received an award from Arcus Biosciences for a project entitled "A Phase 2 Study to Evaluate the Safety and Efficacy of AB122 Monotherapy, AB154 in Combination with AB122, and AB154 in Combination with AB122 and AB928 in Front-Line, Non-Small Cell Lung Cancer." Total funding will be $140,428.

Nancy McGreal of Gastroenterology has received an award from Pfizer, Inc. for a project entitled "OPEN-LABEL INDUCTION AND MAINTENANCE STUDY OF ORAL CP-690,550 (TOFACITINIB) IN CHILDREN WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS." Total funding will be $87,234.

Thomas Leblanc of Hematologic Malignancies and Cellular Therapy has received an award from Carevive Systems, Inc. for a project entitled "Real World Treatment Experience of Patients with Acute Myelogenous Leukemia Using Remote Symptom Monitoring." Total funding will be $56,350.

Jason Somarelli of Medical Oncology has received an award from Karyopharm Therapeutics for a project entitled "Identifying novel CRM1 inhibitor combination therapies to treat sarcomas." Total funding will be $51,161.

Nwora Okeke of Infectious Diseases has received a sub-award (HHSN272201700078) through PPD Investigator Services, LLC for a project entitled "Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID (ACTIV-2/A5401)) - Brii." Total funding has yet to be determined.

Nwora Okeke of Infectious Diseases has received a sub-award (HHSN272201700078) through PPD Investigator Services, LLC for a project entitled "Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID (ACTIV-2/A5401)) - Astrazeneca." Total funding has yet to be determined.

Nwora Okeke of Infectious Diseases has received a sub-award (HHSN272201700078) through PPD Investigator Services, LLC for a project entitled "Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID (ACTIV-2/A5401)) - Sagent Camostat." Total funding has yet to be determined.

Nwora Okeke of Infectious Diseases has received a sub-award (HHSN272201700078) through PPD Investigator Services, LLC for a project entitled "Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID (ACTIV-2/A5401)) - SAB." Total funding has yet to be determined.

Dorothy Sipkins of Hematologic Malignancies and Cellular Therapy has received an award from Bayer HealthCare, LLC for a project entitled "e Window trial to evaluate molecular response of PI3K inhibition with copanlisib in relapsed or refractory adult B-cell acute lymphoblastic leukemia." Total funding has yet to be determined.

Industry Sponsored Research 

Geoffrey Ginsburg of Cardiology has received an award (5U01-HG010225-03S5) from the National Institutes of Health for a project entitled "The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination." Total funding will be $296,034.

Geoffrey Ginsburg of Cardiology has received an award (5U01-HG010225-03S4) from the National Institutes of Health for a project entitled "The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination." Total funding will be $280,812.

Christopher Kontos of Cardiology has received a sub-award (1R01-HL157659-01) through the East Carolina University for a project entitled "Variant Determinants of African American Limb Pathology in Peripheral Arterial Disease." Total funding will be $91,306.

William Jones of Cardiology has received a sub-award through the Harvard Pilgrim Health Care, Inc. for a project entitled "Sentinel Initiative: CDRN Work Order 1:Sentinel Operations Center "RWE: Establish Routine Querying Capability with a Network of EHR Database"." Total funding will be $25,000.

William Jones of Cardiology has received a sub-award (NU-380T000316-) through the The Task Force for Global Health for a project entitled "COVID-19 Electronic Health Data Initiative." Total funding has yet to be determined.

Rowena Dolor of General Internal Medicine has received a sub-award (3-U24TR001608-05S4) through the DCRI-Duke-Site for a project entitled "ACTIV-6: COVID-19 Outpatient Randomized Trial to Evaluate Efficacy of Repurposed Medications."Total funding has yet to be determined.

Cristina Gasparetto of Hematologic Malignancies and Cellular Therapy has received an award from the Prothena Therapeutics Limited for a project entitled "PTND01DM-D001DM." Total funding will be $16,600.

Neelima Navuluri of Pulmonary has received an award from the National Comprehensive Cancer Network for a project entitled "NCCN Foundation 2021 Young Investigator Award - Intervention Mapping to Improve Lung Cancer Screening Among Black Veterans." Total funding will be $150,000.

Neelima Navuluri of Pulmonary has received a sub-award through the American Thoracic Society for a project entitled "Prospective Study of Racial Disparities in Pulmonary and QOL Outcomes among COVID-19 Survivors." Total funding will be $50,000.

Irma Husain (Mentor: Xunrong Luo) of Nephrology has received an award from the ASN Foundation for Kidney Research for a project entitled "Effects of AIF-1 in Ischemic Reperfusion Injury and Transplantation (Fellowship)." Total funding will be $100,000.

Joshua Parsons (Mentor: Vance Fowler) of Infectious Diseases has received an award from the University of North Carolina - Chapel Hill for a project entitled "Parsons UNC Interinstitutional Agreement." Total funding will be $58,011.