New funding awards - November 2017

Friday, December 8, 2017

Sponsored Research

Sana M. Al-Khatib of Cardiology has received a sub-award (1R34-HL132031-01A1) through the University of Pittsburgh for a project entitled "Cardiac Resynchronizatoin in the Elderly: Piloting Pacemaker vs Defibrillator Therapy." Total funding will be $19,686.

Adrian F. Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "PCORnet Phase II Rapid Research TO#13 Mod 1." Total funding will be $79,527.

William E. Kraus of Cardiology has received a sub-award (5P2C-HD086851-03) through the University of Alabama at Birmingham for a project entitled "Develoment of Behavior-Based Circadian Rhythm Index in a PAD Rehabilitation Population Pilot Project." Total funding will be $63,600.

Danielle M. Brander of Hematological Malignancies and Cellular Therapy has received an award from the Dana-Farber Cancer Institute for a project entitled "DFCI Obinutuzumab and Ibrutinib Protocol # 15-283." Total funding will be $119,066.

Marilyn J. Telen of Hematology has received a sub-award (2-D43TW009337-07) through Vanderbilt University for a project entitled "Vanderbilt-Emory-Cornell-Duke Consortium for Global Health Fellows (VECDor)." Total funding will be $72,846.

Susanna Naggie of Infectious Diseases has received a sub-award (5UM1-AI068636-11) through the Brigham and Women's Hospital for a project entitled "ACTG A5327 Protocol Chair Support (PCS)." Total funding will be $24,262.

Nwora L. Okeke of Infectious Diseases has received a sub-award (5R01-AI123001-03) through the Massachusetts General Hospital for a project entitled "Randomized Trial to Prevent Vascular Events in HIV- REPRIEVE (A5332)." Total funding will be $3,663.

Virginia B. Kraus of Rheumatology and Immunology has received an award (1R56-AG054840-01) from the National Institutes of Health for a project entitled "Epigenetic Mechanisms Promoting Longevity." Total funding will be $515,142.

Virginia B. Kraus of Rheumatology and Immunology has received an award from the Arthritis Foundation for a project entitled "Biomarker Demonstration Project for the OA Virtual Center of Excellence." Total funding will be $42,791.

Industry-sponsored Clinical Trials

William S. Jones of Cardiology has received an award from Cardiovascular Systems Inc. for a project entitled "ECLIPSE." Total funding will be $118,700.

Ravi Karra of Cardiology has received an award from Ironwood Pharmaceuticals, Inc. for a project entitled "IW-1973 Caplet." Total funding will be $101,060.

David F. Kong of Cardiology has received an award from Abbott Vascular Devices for a project entitled "Excel." Total funding will be $1,537,563.

Jason Koontz of Cardiology has received an award from the Boston Scientific Corporation for a project entitled "APPRAISE ATP." Total funding will be $57,978.

Richard Krasuski of Cardiology has received an award from VoluMetrix, LLC for a project entitled "Congestive Heart Failure Device." Total funding will be $1,072,822.

Mark E. Leithe of Cardiology has received an award from Boehringer Ingelheim Pharmaceuticals, Inc. for a project entitled "Emperor Reduced HF." Total funding will be $168,558.

Renato D. Lopes of Cardiology has received an award from Eli Lilly and Company for a project entitled "CEC Adjudications for Lilly GIP_GLP1." Total funding will be $111,694.

Renato D. Lopes of Cardiology has received an award from Novartis Pharma AG for a project entitled "Preceptorship for the Andean Cluster." Total funding will be $82,870.

Robert J. Mentz of Cardiology has received an award from Merck for a project entitled "VICTORIA Registry." Total funding will be $2,126,398.

Jonathan P. Piccini of Cardiology has received an award from the Boston Scientific Corporation for a project entitled "APPRAISE ATP." Total funding will be $452,727.

Sudarshan Rajagopal of Cardiology has received an award from United Therapeutics Corporation for a project entitled "Assessing Response to Inhaled Prostacyclin with Hyperpolarized 129Xe MRI." Total funding will be $348,931.

Sudarshan Rajagopal of Cardiology has received an award from United Therapeutics Corporation for a project entitled "TDE-HF-302 Open-label extension study of oral Treprostinil in subjects with Pulmonary Hypertension associated wiht Heart Failure with Preserved Ejection Fraction- A long-term follow-up to TDE-HF-301." Total funding will be $205,816.

Manal F. Abdelmalek of Gastroenterology has received an award from Conatus Pharmaceuticals for a project entitled "A Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial of Emricasan, an Oral Caspase Inhibitor, in Subjects with Decompensated Non-Alcoholic Steatohepatitis (NASH) Cirrhosis." Total funding will be $282,401.

Manal F. Abdelmalek of Gastroenterology has received an award from Intercept Pharmaceuticals, Inc for a project entitled "A Phase 3, Double-Blind, Randomized, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy and Safety of Obeticholic Acid in Subjects with Compensated Cirrhosis due to Nonalcoholic Steatohepatitis." Total funding will be $643,363.

Carl L. Berg of Gastroenterology has received an award from DOVA Pharmaceuticals for a project entitled "DOVA Education Program: Hepatology Update: Chronic Liver Disease Thrombocytopenia." Total funding will be $19,031.

Cathleen S. Colon-Emeric of Geriatrics has received an award from Amgen, Inc. for a project entitled "AMG785 - 2015242." Total funding will be $353,506.

Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from the Celgene Corporation for a project entitled "Celgene Multiple Myeloma Tumor Practicum." Total funding will be $77,884.

Cristina Gasparetto of Hematological Malignancies and Cellular Therapy has received an award from Prothena Therapeutics Limited for a project entitled "A Phase 2b Open-label Extension Study to Evaluate the Long-term Safety and Efficacy of NEOD001 in Subjects with Light Chain (AL) Amyloidosis who were previously enrolled in Study NEOD001-201 (Pronto) previously enrolled in Study NEOD001-201 (PRONTO)." Total funding will be $81,010.

Mitchell E. Horwitz of Hematological Malignancies and Cellular Therapy has received an award from Astellas Pharma Inc. for a project entitled "A Multi-Center, Randomized, Double-Blind, Placebo-Controlled Phae III trial of the FLT3 Inhibitor Gilteritinib Administered as Maintenance Therapy Following Allogeneic Transplant for Patients with FLT3-ITD AML BMT CTN Protocol 1506." Total funding will be $158,908.

Murat O. Arcasoy of Hematology has received an award from the Incyte Corporation for a project entitled "A Double-Blind, Double-Dummy Phase 2 Randomized Study to Evaluate the Efficacy and Safety of Ruxolitinib Versus Anagrelide in Subjects W/ Essential Thromboythemia." Total funding will be $338,028.

Vance G. Fowler of Infectious Diseases has received an award through Basilea Pharmaceuticals for a project entitled "CEC Activities for BPR-CS-009 Ceftobiprole medocaril." Total funding will be $157,319.

Vance G. Fowler of Infectious Diseases has received an award from Genentech, Inc. for a project entitled "A phase 1b, randomized, double-blind, placebo-controlled, multiple-ascending dose study to investigate the safety, tolerability and pharmacokinetics of DSTA4637A in patients with Staphylococcus Aureus Bacteremia receiving standard-of-care antibiotics." Total funding will be $182,635.

Ivy Altomare of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "Protocol A5481082: POLARIS." Total funding will be $225,726.

Andrew Armstrong of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "NEPC Trial PD-1 Inhibition in Neuroendocrine-like Prostate Cancer PD-1 Inhibition or Combination Checkpoint Immuntherapy of Neuroedocrine_Like Prostate Cancer." Total funding will be $330,452.

Kimberly L. Blackwell of Medical Oncology has received an award from the Novartis Pharmaceuticals Corporation for a project entitled "A phase I/Ib, open label study of LSZ102 single agent and LSZ102 in combination with eitherLEE011 (LSZ102 + LEE011) or BYL719 (LSZ102 + BYL719) in patients with advanced or metastatic ER+ breast cancer who have progressed after endocrine therapy." Total funding will be $254,082.

Jeffrey M. Clarke of Medical Oncology has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "A Phase I, Open-Label, Multicenter Study to Assess the Safety, Tolerability, Pharmacokinetics, and Preliminary Anti-Tumor Activity of Ascending Doses of AZD4635 Both as Monotherapy and in Combination with Durvalumab in Patients with Advanced Solid Ma." Total funding will be $301,397.

Michael R. Harrison of Medical Oncology has received an award from Merck for a project entitled "A Phase III Randomized, Controlled Clinical Trial of Pembrolizumab with or without Platinum-Based Combination Chemotherapy versus Chemotherapy in Subjects with Advanced or Metastatic Urothelial Carcin." Total funding will be $351,542.

Michael A. Morse of Medical Oncology has received an award through ASLAN Pharmaceuticals for a project entitled "A Multicenter, Double-Blind, Randomized, Placebo-Controlled Study Of Varlitinib Plus Capecitabine Versus Placebo Plus Capecitabine In Patients With Advanced Or Metastatic Biliary Tract Cancer As Second-Line Systemic Therapy." Total funding will be $399,271.

Hope E. Uronis of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "Key-LARGO: A Single Arm, Phase II Study of Pembrolizumab, Oxaliplatin, and Capecitabine in the First Line Treatment of Patients with Gastro-esophageal Cancer." Total funding will be $999,661.

Kelly E. Westbrook of Medical Oncology has received an award from the Alliance Foundation Trials, LLC for a project entitled "A Randomized, Open Label, Phase III Trial to Evaluate the Efficacy and Safety of Palbociclib + Anti-HER2 Therapy + Endocrine Therapy vs. Anti-HER2 Therapy + Endocrine Therapy after Induction Treatment for Hormone Receptor Positive (HR+)/HER2-Positive." Total funding will be $367,425.

Tian Zhang of Medical Oncology has received an award from Personal Genome Diagnostics, Inc. for a project entitled "A study is to develop a retrospective database to study the PGDx TMB +MSI assay associated with clinical responses to immune checkpoint inhibitors (CPIs)." Total funding will be $25,699.

Tian Zhang of Medical Oncology has received an award from OmniSeq, Inc for a project entitled "A Retrospective Study to Evaluate the Clinical Effectiveness of the OmniSeq Immune Advance Test to Predict Response to Checkpoint Inhibitors." Total funding will be $153,629.

Talal I. Dahhan of Pulmonary, Allergy, and Critical Care Medicine has received an award from Daiichi Sankyo Inc for a project entitled "DS1040-B-U107: Phase 1B, Assess the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of DS-1040B when added to standard of care in subjects with submassive pulmonary embolism." Total funding will be $299,751.

Alice L. Gray of Pulmonary, Allergy, and Critical Care Medicine has received an award from Proteostasis Therapeutics for a project entitled "PTI 801-01." Total funding will be $155,281.