New funding awards - November 2019

Tuesday, December 10, 2019

Sponsored Research

Adrian Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "PCORnet Phase II Surveillance Capacity Building #14 Mod 1." Total funding will be $57,049.

William Jones of Cardiology has received an award from the Rockefeller Philanthropy Advisors, Inc. for a project entitled "Education and Training of Interventional Cardiology and Vascular Medicine Fellows." Total funding will be $47,973.

Anthony Nguyen (Mentor: Robert Lefkowitz) of Cardiology has received an award (1F30-HL149213-01) from the National Institutes of Health for a project entitled "Structural Determination of Novel GPCR Signaling Complexes that Mediate Sustained G Protein Signaling." Total funding will be $187,165.

Yongmei Liu of Cardiology has received a sub-award () through the Wake Forest University Health Sciences for a project entitled "Cell-Specific genomic features of Alzheimer's disease progression Supplment." Total funding will be $387,500.

Katherine Garman of Gastroenterology has received a sub-award (5U54-CA163060-08) through the Case Western Reserve University for a project entitled "Role of CAV3 Mutation in the Pathogenesis of Barrett's Esophagus." Total funding will be $201,966.

Sandeep Dave of Hematologic Malignancies and Cellular Therapy has received a sub-award (1P01-CA233412-01A1) through the Dana-Farber Cancer Institute for a project entitled "Targeting Histone Methylation in PTCL." Total funding will be $322,000.

Sandeep Dave of Hematologic Malignancies and Cellular Therapy has received a sub-award (1P01-CA233412-01A1) through the Dana-Farber Cancer Institute for a project entitled "Core C: Molecular and Pathology Assessment Core." Total funding will be $101,430.

Marilyn Telen of Hematology has received an award from the Doris Duke Charitable Foundation, Inc. for a project entitled "Sharing Comprehensive 'Omics in Sickle Cell Disease Through the NHLBI TOPMed Network." Total funding will be $16,500.

Nathan Thielman of Infectious Diseases has received a sub-award (3D43-TW009337-09) through the Vanderbilt University Medical Center for a project entitled "The impact of HIV infection or exposure on the upper respiratory microbiome of children in Botswana." Total funding will be $95,075.

Nathan Thielman of Infectious Diseases has received a sub-award (3D43-TW009337-09) through the Vanderbilt University Medical Center for a project entitled "Traditional Healers and Mental Health in Nepal." Total funding will be $91,351.

Carey Anders of Medical Oncology has received a sub-award () through the Johns Hopkins University for a project entitled "AURORA US: PROSPECTIVE BIOSPECIMEN REPOSITORY IN METASTATIC BREAST CANCER Tissue Source Site." Total funding will be $1.

Scott Antonia of Medical Oncology has received a sub-award (7JK04) through the H. Lee Moffitt Cancer Center & Research Institute for a project entitled "Targeting Immunosuppressive Cancer Associated Fibroblasts and Immune Checkpoints in NSCLC." Total funding will be $30,860.

Tian Zhang of Medical Oncology has received an award from the Kidney Cancer Association for a project entitled "Immune correlates of immunotherapy responses in renal cell carcinoma." Total funding will be $75,000.

Neelima Navuluri (Mentor: Peter Kussin) of Pulmonary has received an award from the Chest Foundation for a project entitled "Evaluation of Chronic Hypoxemia from Cardiopulmonary Disease Among Patients in Western Kenya and Perspectives on Oxygen Therapy." Total funding will be $10,000.

Kamran Mahmood of Pulmonary has received an award from the Chest Foundation for a project entitled "Lymphocyte Exhaustion Markers in Malignant Pleural Effusions of Lung Cancer." Total funding will be $150,000.

Timothy McMahon of Pulmonary has received a sub-award (5R01-GM113838-05) through the University of Maryland, Baltimore for a project entitled "Sepsis-induced Red Cell Dysfunction (SiRD)." Total funding will be $144,406.

Jamie Todd of Pulmonary has received a sub-award (5U01-AI063594-16) through the Mount Sinai School of Medicine for a project entitled "Hyaluronan in Acute Rejection and Chronic Allograft Dysfunction after Lung Transplantation - CTOT Ancillary." Total funding will be $324,529.

David Leverenz (Mentor: Lisa Criscione-Schreiber) of Rheumatology has received an award from the Rheumatology Research Foundation for a project entitled "RheumMadness: An Online Community of Inquiry for Rheumatology Trainees." Total funding will be $60,000.

Industry-sponsored Clinical Trials

Sudha Shenoy of Cardiology has received an award from Lexicon Pharmaceuticals for a project entitled "Effect of Lexicon compounds on Intrcellular trafficking of GPCRs.." Total funding will be $59,849.

Tracy Wang of Cardiology has received an award from CryoLife for a project entitled "PROACT II - Prospective Randomized On-X Anticoagulation Clinical Trial." Total funding will be $27,726,975.

Jonathan Campbell of Endocrinology has received an award from Novo Nordisk, Inc. for a project entitled "Using islet perifusion to discover novel regulators of ¿-cell function." Total funding will be $209,260.

Deborah Muoio of Endocrinology has received an award from AstraZeneca AB for a project entitled "Duke Molecular Physiology Institute-Maastricht University Collaborative Project for AstraZeneca." Total funding will be $181,086.

Manal Abdelmalek of Gastroenterology has received an award from Celgene Corporation for a project entitled "Celgene CC-90001 NASH-001." Total funding will be $407,616.

Manal Abdelmalek of Gastroenterology has received an award from Galmed Pharmaceuticals Ltd. for a project entitled "ARMOR." Total funding will be $210,926.

Manal Abdelmalek of Gastroenterology has received an award from Genentech, Inc. for a project entitled "Genentech GC41003." Total funding will be $74,822.

Jun Chen of Hematologic Malignancies and Cellular Therapy has received an award from NeoImmuneTech, Inc. for a project entitled "Mitigation of radiation-induced hematopoietic toxicity by rhIL-7-hyFc." Total funding will be $483,000.

Taewoong Choi of Hematologic Malignancies and Cellular Therapy has received an award from Jazz Pharmaceuticals for a project entitled "Prospective, Multicenter, Open-Label, Single Arm, Phase 2 Study to Evaluate the Safety and Efficacy of Defibrotide in the Prevention of Chimeric Antigen Receptor-T-cell-associated Neurotoxicity in Subjects with Relapsed or Refractory Diffuse Large B-." Total funding will be $241,610.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from Amgen, Inc. for a project entitled "Amgen Tower rollover study-Study 20180138: Long-term follow-up of adult Philadelphia chromosome negative acute lymphoblastic." Total funding will be $18,618.

Anthony Sung of Hematologic Malignancies and Cellular Therapy has received an award from Merck Sharp & Dohme for a project entitled "A Phase 3 randomized, double-blind, placebo-controlled clinical trial to evaluate the safety and efficacy of letermovir (LET) prophylaxis when extended from 100days to 200 days post-transplant in cytomegalovirus (CMV) seropositive recipients (R+)." Total funding will be $519,005.

Nirmish Shah of Hematology has received an award from Imara, Inc. for a project entitled "A Phase 2a, Randomised, Double Blind, Placebo-Controlled Study of IMR-687 in Adult Patients with Sickle Cell Anaemia (Homozygous HbSS or Sickle-B thalassemia.." Total funding will be $186,564.

Gregory Gray of Infectious Diseases has received a sub-award (N6264518D5058) through Vysnova Partners, Inc. for a project entitled "Leptospirosis Febrile Site Surveillance In Sarawak, Malaysia." Total funding will be $25,444.

Carey Anders of Medical Oncology has received an award from Nektar Therapeutics for a project entitled "A PHASE 3 OPEN-LABEL, RANDOMIZED, MULTICENTER STUDY OF NKTR-102 VERSUS TREATMENT OF PHYSICIAN'S CHOICE (TPC) IN PATIENTS WITH METASTATIC BREAST CANCER WHO HAVE STABLE BRAIN METASTASES AND HAVE BEEN PREVIOUSLY TREATED WITH AN ANTHRACYCLINE, A TAXANE,." Total funding will be $150,479.

William Berry of Medical Oncology has received an award from Merck for a project entitled ""A Phase 3, Randomized Open-label Study of Pembrolizumab (MK-3475) Plus Olaparib Versus Abiraterone Acetate or Enzalutamide in Participants with Metastatic Castrationresistant Prostate Cancer (mCRPC) Who are Unselected for Homologous Recombination Re." Total funding will be $873,402.

Kelly Marcom of Medical Oncology has received an award from GlycoMimetics, Inc for a project entitled "GMI-1359-210." Total funding will be $895,984.

Niharika Mettu of Medical Oncology has received an award from ERYTECH Pharma for a project entitled "A Randomized, Phase 3 Study of Eryaspase in Combination with Chemotherapy versus Chemotherapy Alone as Second-Line Treatment in Patients with Pancreatic Adenocarcinoma TRYbeCA-1 ¿ TRial of erYaspase in pancreatic CAncer." Total funding will be $391,956.

Niharika Mettu of Medical Oncology has received an award from Incyte Corporation for a project entitled "A Phase 2, Open-Label, Single-Arm, Multicenter Study to Evaluate the Efficacy and Safety of Pemigatinib in Participants With Previously Treated Locally Advanced/Metastatic or Surgically Unresectable Solid Tumor Malignancies Harboring Activating FGFR." Total funding will be $378,950.

April Salama of Medical Oncology has received an award from Array BioPharma Inc for a project entitled "A Phase 2, Open-Label, Randomized, Multicenter Trial of Encorafenib + Binimetinib Evaluating a Standard-dose and a High-dose Regimen in Patients With BRAFV600-Mutant Melanoma Brain Metastasis." Total funding will be $212,664.

Sarah Sammons of Medical Oncology has received an award from Bristol-Myers Squibb Company for a project entitled "A Randomized, Multicenter, Double-blind, Placebo-controlled Phase 3 Study of Nivolumab VersusPlacebo in Combination With Neoadjuvant Chemotherapy and Adjuvant Endocrine Therapy in Patients WithHigh-risk, Estrogen Receptor-Positive (ER+), Human Epider." Total funding will be $467,786.

Thomas Stinchcombe of Medical Oncology has received an award from Novartis Pharmaceuticals Corporation for a project entitled "A randomized, double-blind, placebo-controlled, phase III study evaluating the efficacy and safety of embrolizumab plus platinum-based doublet chemotherapy with or without canakinumab as first line therapy for locally advanced or metastatic non-squam." Total funding will be $296,005.

John Strickler of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "Mountaineer-Phase ll (ACCRU)." Total funding will be $1,963,050.

Kelly Westbrook of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "Randomized, double-blind, phase 3 study of tucatinib or placebo in combination with ado-trastuzumab emtansine (T-DM1) for subjects with unresectable locally-advanced or metastatic HER2+ breast cancer." Total funding will be $308,200.

Hakim Ali of Pulmonary has received an award from 4Dx Limited for a project entitled "Novel 4Dx functional lung imaging in diagnosis and follow up of CLAD." Total funding will be $39,452.

Stephen Bergin of Pulmonary has received an award from Karius, Inc. for a project entitled "Pneumonia in the Immunocompromised - Use of the Karius Test for the Detection of Undiagnosed Pathogens(Pickup)." Total funding will be $173,937.

Patricia Lugar of Pulmonary has received an award from Shire Human Genetics Therapies for a project entitled "HAE Outcome Study. An observational, non-interventional, study of patients with Hereditary Angioedema in the United States and Canada.." Total funding will be $108,033.

Kamran Mahmood of Pulmonary has received an award from Nuvaira, Inc. for a project entitled "Airflow 3: Multicenter randomized sham-controlled study to evaluate safety and efficacy after treatment with the Nuvaira Lung Denervation System in subjects with COPD." Total funding will be $177,414.

Scott Palmer of Pulmonary has received an award from AstraZeneca AB for a project entitled "Chronic Lung Allograft Dysfunction." Total funding will be $582,400.

Robert Keenan of Rheumatology has received an award from Horizon Pharma Rheumatology for a project entitled "Pegloticase in Uncontrolled Gout who have undergone Kidney Transplant." Total funding will be $303,503.