New funding awards - October 2020

Wednesday, November 18, 2020

Sponsored Research

William Kraus of Cardiology has received an award (5U01-AR071128-04) from the National Institutes of Health for a project entitled "Molecular Transducers of Physical Activity and Health: NC Consortium Clinical Site." Total funding will be $35,942.

Deborah Muoio of Endocrinology has received a sub-award (5R01-DK120296-02) through the East Carolina University for a project entitled "Metabolic inflexibility is related to elevated muscle anaerobic glycolysis." Total funding will be $74,632.

L. Ebony Boulware of General Internal Medicine has received an award from the National Institutes of Health for a project entitled "Bruce Burnett IPA." Total funding will be $118,952.

Vance Fowler of Infectious Diseases has received an award (3UM1-AI104681-08S1) from the National Institutes of Health for a project entitled "Antibacterial Resistance Leadership Group (ARLG)." Total funding will be $56,350.

Cameron Wolfe of Infectious Diseases has received a sub-award (HHSO100201400002I) through the DCRI-Duke-Site for a project entitled "ACTIV1: Master Protocol for Immune Modulars: Remdisivir in COVID 19 patients." Total funding will be $0.

Jennifer Freedman of Medical Oncology has received an award (1R01-CA253312-01) from the National Institutes of Health for a project entitled "Race-related differential RNA splicing: novel targets for precision oncology in non-small cell lung cancer." Total funding will be $1,791,915.

Pao-Hwa Lin of Nephrology has received an award from the Institute for Medical Research, Inc. for a project entitled "Carbohydrate and Prostate Study 1 and 2." Total funding will be $7,999.

Christina Wyatt of Nephrology has received a sub-award (5U01-AI0969299-12) through the Albert Einstein College of Medicine for a project entitled "Central Africa International Epidemiologic Database to Evaluate AIDS." Total funding will be $17,478.

Scott Palmer of Pulmonary has received a sub-award (5U01-AI063594-17) through the Icahn School of Medicine at Mount Sinai for a project entitled "Club Cells and CCSP in the pathogenesis of CLAD/spatial transcriptomics." Total funding will be $279,737.

Rebecca Sadun of Rheumatology has received an award from the Arthritis Foundation for a project entitled "Arthritis Foundation Fellowship Training Grant 2019." Total funding will be $150,000.

Industry-sponsored Clinical Trials

William Herzog of Cardiology has received an award from Amgen, Inc. for a project entitled "cvMOBIUS." Total funding will be $271,925.

William Herzog of Cardiology has received an award from PhaseBio Pharmaceuticals, Inc. for a project entitled "A Phase 3, Multicenter, Open-Label, Single-Arm Study of PB2452 in Ticagrelor-Treated Patients with Uncontrolled Major or Life-Threatening Bleeding or Requiring Urgent Surgery or Invasive Procedure." Total funding will be $130,845.

Michel Khouri of Cardiology has received an award from Ionis Pharmaceuticals Inc for a project entitled "Strategy to Improve Patient Outcomes by Silencing TTR Formation in ATTR-CM." Total funding will be $377,424.

Robert McGarrah III of Cardiology has received an award from Amgen, Inc. for a project entitled "cvMOBIUS." Total funding will be $271,920.

Robert Mentz of Cardiology has received an award from Eggland's Best, LLC for a project entitled "PROSPective evaluation of Eggland's Best Related to Improvement in The biomarker profile for Your health." Total funding will be $855,780.

Martin Moseley III of Cardiology has received an award from Arbiom for a project entitled "LC-MS based proteomic characterization of yeast proteomes as a function of growth substrate." Total funding will be $10,177.

Sreekanth Vemulapalli of Cardiology has received an award from Abbott Laboratories for a project entitled "Clinical Phenotypes and Outcomes Associated with Tricuspid Regurgitation." Total funding will be $240,816.

Manal Abdelmalek of Gastroenterology has received an award from Hanmi Pharmaceutical for a project entitled "A Phase 2, Randomized, Double-Blind, Placebo-Controlled, Parallel Group Study to Evaluate the Efficacy, Safety and Tolerability of HM15211 Treatment for 12 Months in Subjects with Biopsy Confirmed NASH." Total funding will be $448,685.

Rebecca Burbridge of Gastroenterology has received an award from Boston Scientific Corporation for a project entitled "Duke Training Grant in Advanced Gastrointestinal Endoscopy." Total funding will be $25,000.

Karen Chachu of Gastroenterology has received an award from Janssen Research & Development, LLC for a project entitled "A Study of the Efficacy and Safety of Guselkumab in Participants with Moderately to Severely Active Ulcerative Colitis." Total funding will be $459,794.

Danielle Brander of Hematologic Malignancies and Cellular Therapy has received an award from Novartis Pharmaceuticals Corporation for a project entitled "Novartis: CVAY736Y2102 Ph1b VAY736 and Ibrutinib patients with CLL on Ibrutinib therapy." Total funding will be $277,097.

Cristiana Costa Chase of Hematologic Malignancies and Cellular Therapy has received an award from Ichnos Science, S.A. for a project entitled "Glenmark Bite." Total funding will be $419,774.

Richard Lopez of Hematologic Malignancies and Cellular Therapy has received an award from Pharmerit International for a project entitled "Retrospective Observational Study Protocol: Chart Review Study to Characterize Extracorporeal Photopheresis (ECP) Early Responders ECP Early Responder Patient Chart Review." Total funding will be $12,051.

Lindsay Rein of Hematologic Malignancies and Cellular Therapy has received an award from Imago BioSciences for a project entitled "A Phase 2 Multi-Center, Open Label Study to Assess the Safety, Efficacy and Pharmacodynamics of IMG-7289 in Patients with Essential Thrombocythemia." Total funding will be $246,442.

Nwora Okeke of Infectious Diseases has received a sub-award (HHSN272201700078C) through PPD Investigator Services, LLC for a project entitled "Adaptive Platform Treatment Trial for Outpatients with COVID-19 (Adapt Out COVID (ACTIV-2/A5401))." Total funding will be $1.

Cameron Wolfe of Infectious Diseases has received an award from Ridgeback Biotherapeutics LP for a project entitled "Ph IIa, randomized, double blind placebo controlled trial of EIDD-2801 to eliminate COVID Viral RNA detection." Total funding will be $107,685.

James Abbruzzese of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "Pfizer - C4201002 - PF-07265807." Total funding will be $496,146.

Andrew Armstrong of Medical Oncology has received an award from Amgen, Inc. for a project entitled "Protocol No. 20180146 entitled "A Phase 1 Study Evaluating the Safety, Tolerability, Pharmacokinetics, and Efficacy of AMG 509 in Subjects With Metastatic Castration-Resistant Prostate Cancer." Total funding will be $1,883,900.

Jennifer Choe of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "MK-7902-009-00 LEAP-009." Total funding will be $1,276,288.

Jeffrey Clarke of Medical Oncology has received an award from Cellular Biomedicine Group, Inc. for a project entitled "CBMG NSCLC Tumor Specimens for TIL Cell Therapy." Total funding will be $28,748.

Christopher Hoimes of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "An open-label, randomized, controlled phase 3 study of enfortumab vedotin in combination with pembrolizumab with or without chemotherapy, versus chemotherapy alone in previously untreated locally advanced or metastatic urothelial cancer." Total funding will be $395,142.

Richard Riedel of Medical Oncology has received an award from Tracon Pharmaceuticals, Inc. for a project entitled "ENVASARC: A PIVOTAL TRIAL OF ENVAFOLIMAB, AND ENVAFOLIMAB IN COMBINATION WITH IPILIMUMAB, IN PATIENTS WITH ADVANCED OR METASTATIC UNDIFFERENTIATED PLEOMORPHIC SARCOMA OR MYXOFIBROSARCOMA WHO HAVE PROGRESSED ON PRIOR CHEMOTHERAPY." Total funding will be $245,001.

Sarah Sammons of Medical Oncology has received an award from AbbVie Inc. for a project entitled "A Phase 1, Multicenter, Open-Label Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of Combinations of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Subjects with Locally Advanced or Meta." Total funding will be $353,870.

John Strickler of Medical Oncology has received an award from Daiichi Sankyo Inc for a project entitled "Daiichi Sankyo - Safety and Efficacy of U3-1402 in Subjects with Advanced or Metastatic Colorectal Cancer." Total funding will be $490,201.

John Strickler of Medical Oncology has received an award from Seattle Genetics, Inc for a project entitled "SGNTUC-022 Tucatinib, trastuzumab, ramucirumab, and paclitaxel versus paclitaxel and ramucirumab in previously treated HER2+ gastroesophageal cancer." Total funding will be $383,808.

Hope Uronis of Medical Oncology has received an award from Leap Therapeutics, Inc. for a project entitled "DEK-DKK1-P205." Total funding will be $543,373.