New funding awards - September 2015

Thursday, October 8, 2015

Sponsored Research

Geoffrey S. Ginsburg of Cardiology has received an award (3U01-HG007282-03S2) from the National Institutes of Health for a project entitled "Implementing Familial Hypercholesterolemia Cascade Screening: A Feasibility Pilot." Total funding will be $152,421.

Geoffrey S. Ginsburg of Cardiology has received an award (3U01-HG007282-03S1) from the National Institutes of Health for a project entitled "Leading and Managing the IGNITE Common Measures Working Group." Total funding will be $140,538.

Adrian F. Hernandez of Cardiology has received an award (3U54-AT007748-04S1) from the National Institutes of Health for a project entitled "Health Care Systems Research Collaboratory Diversity Supplement." Total funding will be $514,963.

Christopher Kontos of Cardiology has received an award (3T32-GM007171-41S1) from the National Institutes of Health for a project entitled "Medical Scientist Training Program." Total funding will be $50,614.

Chiara Melloni of Cardiology has received an award (HHSN27500043) from the National Institutes of Health for a project entitled "PTN TO#TBD POPS IV." Total funding will be $324,244.

Chiara Melloni of Cardiology has received an award (HHSN27500037) from the National Institute for Child Health & Human Development for a project entitled "PTN TO#38 Efficacy, Pharmacokinetics, and Safety of Topical Timolol in Infants." Total funding will be $1,851,655.

Paul B. Rosenberg of Cardiology has received an award (1R21-NS090327-01A1) from the National Institutes of Health for a project entitled "STIM1-dependent calcium signaling in neuronal responses to hypoxia and ischemia." Total funding will be $437,250.

Gillian D. Schmidler of Cardiology has received an award (HHSA290201500004I-TO6) from the Agency for Healthcare Research and Quality for a project entitled "EPC V - TO#13 - Treatment Strategies for Patients with Lower Extremity Peripheral Venous Disease." Total funding will be $500,000.

Gillian D. Schmidler of Cardiology has received an award (HHSA290201500004I TO2 Op) from the Agency for Healthcare Research and Quality for a project entitled "Attention Deficit Hyperactivity Disorder (ADHD) - EPC TO #2 Item 7 Opt task." Total funding will be $355,000.

Svati H. Shah of Cardiology has received an award (1R56-HL129880-01) from the National Institutes of Health for a project entitled "Systems Biology Approaches for Predicting Cardiometabolic Risk in Persons Living with HIV." Total funding will be $658,233.

Deepak Voora of Cardiology has received an award (3R01-HL118049-03S2) from the National Institutes of Health for a project entitled "Platelet metbalomic profiling and the response to aspirin." Total funding will be $158,979.

Mary E. Klotman of Chair's Office has received an award (1R01-DK108367-01) from the National Institutes of Health for a project entitled "The Genitourinary Tract as a compartment and reservoir for HIV." Total funding will be $2,409,113.

David D'Alessio of Endocrinology, Metabolism, and Nutrition has received a sub-award (R01-DK076092-09) through the Tufts Medical Center for a project entitled "The Role of Vitamin D in Established Type 2 Diabetes." Total funding will be $109,212.

Michael T. Davidson (Mentor: Deborah Muoio) of Endocrinology, Metabolism, and Nutrition has received an award (1F30-DK108560-01) from the National Institutes of Health for a project entitled "Carnitine Acetyltransferase and Metabolic Regulation in the Exocrine Pancreas." Total funding will be $82,794.

Kelsey Fisher-Wellman (Mentor: Deborah Muoio) of Endocrinology, Metabolism, and Nutrition has received an award (1 F32-DK105665-01A1) from the National Institutes of Health for a project entitled "Role of Protein Malonylation in Regulating Mitochondrial Function." Total funding will be $168,198.

John R. Guyton of Endocrinology, Metabolism, and Nutrition has received an award from the The FH Foundation for a project entitled "CASCADE FH Registry: Cascade Screening for Awaremess and Detection of Familial Hypercholesterolemia."

Anna Mae Diehl of Gastroenterology has received an award (1R56-DK106633-01) from the National Institutes of Health for a project entitled "Pathogenesis of NASH Cirrhosis." Total funding will be $278,250.

Hayden B. Bosworth of General Internal Medicine has received an award from the PhRMA Foundation for a project entitled "Evaluating CVD Medication Adherence Program in Low SES." Total funding will be $126,360.

Leigh Boulware of General Internal Medicine has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "Putting Patients at the Center of Kidney Care Transitions." Total funding will be $5,600,114.

Farr Curlin of General Internal Medicine has received a sub-award through the Rush University Medical Center for a project entitled "Training Research-Literate Chaplains as Ambassadors for Spirituality and Health: Phase I." Total funding will be $17,742.

Adam Perlman of General Internal Medicine has received an award (3R01-AT004623-07S1) from the National Institutes of Health for a project entitled "Multisite RCT Investigating the Efficacy of Massage in Osteoarthritis." Total funding will be $30,904.

John Williams of General Internal Medicine has received an award (HHSA290201500004I TO5) from the Agency for Healthcare Research and Quality for a project entitled "EPC V RFTO 10: Transparency of Reporting Requirement." Total funding will be $25,000.

Harvey Jay Cohen of Geriatrics has received an award (2T32-AG000029-39) from the National Institutes of Health for a project entitled "Behavioral and Physiology in Aging." Total funding will be $1,805,133.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award (W81XWH-15-1-0443) from the Department of Defense for a project entitled "A novel therapeutic target for radiation-induced hematological malignancies: calcium calmodulin kinase 2." Total funding will be $475,959.

Nelson J. Chao of Hematological Malignancies and Cellular Therapy has received an award (2U19-AI067798-11) from the National Institutes of Health for a project entitled "Core A - Administrative." Total funding will be $2,140,697.

Stefanie Sarantopoulos of Hematological Malignancies and Cellular Therapy has received an award from the Leukemia & Lymphoma Society for a project entitled "The Notch2-BCR Axis: Targeting Drivers of B cell Fate in Chronic GVHD." Total funding will be $200,000.

Grace M. Lee of Hematology has received an award (1K08-HL127183-01) from the National Institutes of Health for a project entitled "Biological Significance of Protamine/Heparin Antibodies." Total funding will be $637,135.

Thomas L. Ortel of Hematology has received an award from the Bristol-Myers Squibb Foundation for a project entitled "This is Serious VTE patient education." Total funding will be $120,000.

Thomas L. Ortel of Hematology has received a sub-award (U36-OE000004-04) through the Centers for Disease Control and Prevention for a project entitled "Population-based Surveillance and Outcomes of Venous Thromboembolism." Total funding will be $186,100.

Nirmish R. Shah of Hematology has received an award (1557730) from the National Science Foundation for a project entitled "QuBBD: Collaborative Research: Advancing Health using Big Data Analytics: Statistical and Dynamical Systems Modeling of Real-Time Adaptive m-Intervention for Pain." Total funding will be $27,030.

J. Brice Weinberg of Hematology has received an award (1R01-HL130763-01) from the National Institutes of Health for a project entitled "Nitric Oxide and Microvascular Dysfunction in Severe Malaria." Total funding will be $1,406,273.

Vivian H. Chu of Infectious Diseases has received a sub-award (R01-DE023375) through the Carolinas Medical Center for a project entitled "Oral Hygiene, Periodontal Disease and Infective Endocarditis." Total funding will be $10,251.

Vance G. Fowler of Infectious Diseases has received a sub-award (GTN1018930) through the Menzies School of Health Research for a project entitled "CAMERA:  Combination antibiotic treatment for Methicillin Resistant Staphylococcus Aureus Bacteraemia-a Randomized Controlled Trial."

Greg Gray of Infectious Diseases has received an award (7R24-TW009546-03) from the National Institutes of Health for a project entitled "One Health Center for Environmental and Occupational Research-Romania/United States." Total funding will be $21,909.

Mehri McKellar of Infectious Diseases has received a sub-award (2H12-HA24815 04-00) through the New Hanover Regional Medical Center for a project entitled "Ryan White HIV/AIDS Program Part D Support Services." Total funding will be $106,110.

Arif H. Kamal of Medical Oncology has received an award (1K08-HS023681-01A1) from the Agency for Healthcare Research and Quality for a project entitled "Which palliative care quality measures improve patient-centered outcomes?" Total funding will be $733,695.

P. Kelly Marcom of Medical Oncology has received an award from the Beth Israel Deaconess Medical Center for a project entitled "TBCRC 031 INFORM (Beth Israel)." Total funding will be $26,500.

P. Kelly Marcom of Medical Oncology has received an award from the Johns Hopkins University for a project entitled "Randomized phase II trial of neoadjuvant cisplatin vs. doxorubicin/cyclophosphamide in women with newly diagnosed breast cancer and germline BRCA mutations." Total funding will be $21,540.

Rasheeda K. Hall of Nephrology has received an award from the American Society of Nephrology for a project entitled "Improving Quality of Life Measurement of Older Dialysis Patients." Total funding will be $25,000.

David M. Brass of Pulmonary, Allergy, and Critical Care Medicine has received an award (200-2015-M-61643) from the National Institute for Occupational Safety and Health for a project entitled "NIOSH serum sample analysis." Total funding will be $7,613.

Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from the Columbia University for a project entitled "Whole Exome Sequencing of Idiopathic Pulmonary Fibrosis Patients." Total funding will be $57,402.

Karen Welty-Wolf of Pulmonary, Allergy, and Critical Care Medicine has received an award (HR0011-15-2-0057) from the Defense Advanced Research Projects Agency for a project entitled "Novel Dialysis-Like Therapeutics in Sepsis-induced Shock and Organ Failure." Total funding will be $986,032.

Yen Rei Yu of Pulmonary, Allergy, and Critical Care Medicine has received an award (1K08-HL121185-01A1) from the National Institutes of Health for a project entitled "Role of Resident Monocytes in the Pathogenesis of Pulmonary Arterial Hypertension." Total funding will be $597,240.

Industry-sponsored clinical trials

Robert J. Mentz of Cardiology has received an award from Medtronic, Inc. for a project entitled "MED-012 OptiVol for Volume." Total funding will be $49,024.

Eric D. Peterson of Cardiology has received an award from Janssen Scientific Affairs, LLC. for a project entitled "Assessing and Improving Quality of Care for Patients with Atrial Fibrillation." Total funding will be $86,986.

Zainab Samad of Cardiology has received an award from Medtronic, Inc. for a project entitled "MED-011." Total funding will be $113,897.

Tracy Y. Wang of Cardiology has received an award from AstraZeneca LP for a project entitled "Affordability and Real-World antiplatelet treatment effectiveness after myocardial infarction study." Total funding will be $32,700.

Tracy Y. Wang of Cardiology has received an award from Regeneron Pharmaceuticals, Inc. for a project entitled "Patient and Provider Assessment of Lipid Management." Total funding will be $22,001.

Thomas J. Weber of Endocrinology, Metabolism, and Nutrition has received an award from Ultragenyx Pharmaceutical for a project entitled "A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Assess the Efficacy and Safety of KRN23 in Adult Patients with X-linked Hypophosphatemia (XLH)." Total funding will be $42,519.

Nancy M. McGreal of Gastroenterology has received an award from AbbVie Inc. for a project entitled "Cape Registry- P11292." Total funding will be $430,664.

Andrew J. Muir of Gastroenterology has received an award from Gilead Sciences, Inc. for a project entitled "HCV RNA Monitoring for Gilead's A Phase 3, Open-label Study." Total funding will be $264,666.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Flexus Biosciences, Inc for a project entitled "Phase 1/1b, First-in-Human, Dose-Escalation and Expansion Study of FLX925 Administered Orally to Subjects with R/R AML." Total funding will be $102,276.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Ambit Biosciences for a project entitled "A Phase 3 Open-Label Randomized Study of Quizartinib (AC220) Monotherapy versus salvage chemotherapy in subjects with FLT3-ITD Positive Acute Myeloid Leukemia (AML) Refractory to or Relapsed after First-Line treatment w/wo Hematopoietic stem cell TRA." Total funding will be $135,843.

Greg Gray of Infectious Diseases has received an award from Life Technologies for a project entitled "Comparison of PRRSV Assays in Detecting Viral RNA from Swine Serum." Total funding will be $7,542.

Ephraim L. Tsalik of Infectious Diseases has received an award from bioMerieux, Inc. for a project entitled "Relationship between acute respiratory pathogen detection and procalcitonin." Total funding will be $9,984.

Stephanie Gaillard of Medical Oncology has received an award from Gradalis, Inc. for a project entitled "CL-PTL-119: Double-Blind, Placebo Controlled Phase III Trial of Maintenance FANG (bi-shRNAfurin and GMCSF Augmented Autologous Tumor Cell Immunotherapy) for High Risk Stage III/IV Ovarian Cancer." Total funding will be $186,732.

Neal E. Ready of Medical Oncology has received an award from AbbVie Inc. for a project entitled "Abbvie M14-361, A Phase I Dose Escalation and Phase 2 Randomized Double-Blind Study of Veliparib in Combination with Carboplatin and Etoposide as a Therapy of Treatment-Naive Extensive Stage Disease Small Cell Lung Cancer." Total funding will be $596,780.

April K. Salama of Medical Oncology has received an award from Celldex Therapeutics, Inc. for a project entitled "A Phase II Study of Glembatumumab Vedotin, an Anti-gpNMB Antibody -Drug Conjugate, in Patients with Advanced Melanoma." Total funding will be $83,300.

Linda M. Sutton of Medical Oncology has received an award from Pfizer, Inc. for a project entitled "Metastatic Renal Cell Cancer Registry (MaRCC Registry)." Total funding will be $66,470.

Tian Zhang (Mentor: Daniel J. George) of Medical Oncology has received an award from Acerta Pharma for a project entitled "ACE-ST-005: Randomized Phase 2 Trial of ACP-196 and Pembrolizumab Immunotherapy Dual CHECKpoint Inhibition In Platinum Resistant Metastatic Urothelial Carcinoma (RAPID CHECK study)." Total funding will be $2,499,456.

Shelby Reed of Other Medicine has received an award from Sanofi US for a project entitled "Quantifying Patient Preferences for Diabetes Treatment Intensification." Total funding will be $289,184.

Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Gilead Sciences, Inc. for a project entitled "Determine the Role of LOXL2 in Experimental Bronchiolitis Obliterans." Total funding will be $120,000.

Scott M. Palmer of Pulmonary, Allergy, and Critical Care Medicine has received an award from Genentech, Inc. for a project entitled "Genentech BOS Feasibility." Total funding will be $36,375.

David S. Pisetsky of Rheumatology and Immunology has received an award from Pfizer, Inc. for a project entitled "ANA and Anti-DNA as Criteria for Enrollment in Lupus Clinical Trials." Total funding will be $247,275.