New funding awards - September 2017

Wednesday, October 11, 2017

Sponsored Research

Christopher Granger of Cardiology has received a sub-award through the Harvard Pilgrim Health Care, Inc. for a project entitled "IMPACT AFib (Phase 2): FDA-Catalyst and Broader Use of Sentinel Infrastructure." Total funding will be $110,463.

Adrian F. Hernandez of Cardiology has received an award (3U54-AT007748-05S2) from the National Institutes of Health for a project entitled "Health Care Systems Research Collaboratory - Training Supplement." Total funding will be $381,943.

William S. Jones of Cardiology has received a sub-award (5U01-HL130163-02) through the Brigham and Women's Hospital for a project entitled "Influenza Vaccine to Effectively Stop Cardio Thoracic Events and Decompensated heart failure."

Robert J. Lefkowitz of Cardiology has received an award (3R01-HL016037-45S1) from the National Institutes of Health for a project entitled "Molecular Regulation of Cardiovascular 7 TM Receptors." Total funding will be $334,002.

Chiara Melloni of Cardiology has received an award (HHSN27520100003I TO49) from the National Institutes of Health for a project entitled ""Pharmacokinetics of understudied drugs administered to children per standard of care (POPS) V"." Total funding will be $2,005,120.

Chiara Melloni of Cardiology has received an award (HHSN27520100003I TO50) from the National Institutes of Health for a project entitled "PTN_TO#50 POPS LAB." Total funding will be $1,576,627.

Sudarshan Rajagopal of Cardiology has received an award (1R01-GM122798-01A1) from the National Institutes of Health for a project entitled "Biasing CXCR3 Signaling to Modulate the Inflammatory Response." Total funding will be $1,558,086.

Sudarshan Rajagopal of Cardiology has received an award (1R03-HL139946-01) from the National Institutes of Health for a project entitled "Probing the Mechanism of VEGFR3 regulation by Beta-rrwatins in Vascular Disease." Total funding will be $159,000.

Howard A. Rockman of Cardiology has received an award from the Edna and Fred L. Mandel, Jr. Foundation for a project entitled "Rockman Lab- Mandel Foundation," a part of Victor J. Dzau's project entitled "Mandel Foundation 2017-2018." Total funding will be $59,800.

Svati H. Shah of Cardiology has received an award (1R56-HL129880-01) from the National Institutes of Health for a project entitled "Systems Biology Approaches for Predicting Cardiometabolic Risk in Persons Living with HIV." Total funding will be $658,233.

Eric Velazquez of Cardiology has received an award (1U01-HL125511-01A1) from the National Institutes of Health for a project entitled "TRANSFORM-HF CCC." Total funding will be $7,706,200.

Jonathan Douros (Mentor: David D'Alessio) of Endocrinology, Metabolism, and Nutrition has received an award (1F32-DK115031-01) from the National Institutes of Health for a project entitled "Assessing the Role of Glucose-Dependent Insulinotropic Polypeptide to Mediate Improved Beta-Cell Function Following Bariatric Surgery." Total funding will be $132,660.

Alec G. Trub (Mentor: Matthew D. Hirschey) of Endocrinology, Metabolism, and Nutrition has received an award (1F31-HL139140-01) from the National Institutes of Health for a project entitled "Statin-induced Increases in HMG-CoA lead to HMG-modified Fatty Acid Synthase." Total funding will be $105,069.

Anna Barton (Mentor: William Yancy) of General Internal Medicine has received an award from the Diabetes Action Research and Education Foundation for a project entitled "Examining the Use and Effectiveness of a Very Low-Carbohydrate Diet in Type 1 Diabetes." Total funding will be $10,000.

Keisha Bentley-Edwards of General Internal Medicine has received an award (1R01-MD011606-01A1) from the National Institutes of Health for a project entitled "Religion, Spirituality and CVD Risks: A Focus on African Americans." Total funding will be $2,713,229.

Susanne B. Haga of General Internal Medicine has received an award (1R25-HG009644-01) from the National Institutes of Health for a project entitled "Summer Scholars Program in Genome Sciences and Medicine." Total funding will be $1,056,524.

Christopher B. Bowling of Geriatrics has received an award (7R01-HL133618-02) from the National Institutes of Health for a project entitled "Sustained blood pressure control and progression of multimorbidity." Total funding will be $1,248,316.

Cathleen S. Colon-Emeric of Geriatrics has received an award (1UH2-AG056925-01) from the National Institutes of Health for a project entitled "Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative (PRIME Collaborative)." Total funding will be $2,019,968.

Phuong L. Doan of Hematological Malignancies and Cellular Therapy has received a sub-award (5U19-AI067773-13) through Columbia University for a project entitled "Endothelial Cell-Derived Extracellular Vesicles Mitigate Hematopoietic Injury Following Ionizing Radiation." Total funding will be $159,000.

James White of Hematology has received an award (1K01-AG056664-01) from the National Institutes of Health for a project entitled "The AMPK/ULK1/p27Kip1 axis regulates autophagy and cell survival in aged satellite cells." Total funding will be $612,630.

Gregory Gray of Infectious Diseases has received an award from the US Department of State for a project entitled "Duke One Health Training Program." Total funding will be $452,533.

Gregory Gray of Infectious Diseases has received an award from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal Interface in Morocco."

Gregory Gray of Infectious Diseases has received an award from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal Interface in Philippines." Total funding will be $253,205.

Gregory Gray of Infectious Diseases has received an award from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal Interface in Pakistan." Total funding will be $276,937.

Gregory Gray of Infectious Diseases has received an award from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal Interface in Turkey."

Gregory Gray of Infectious Diseases has received an award from the US Department of State for a project entitled "Detecting Novel Respiratory Viruses that Emerge from the Human-Animal Interface in Yemen."

Wendy A. Prudhomme - O'Meara of Infectious Diseases has received an award through Indiana University for a project entitled "AMPATH-KEVA (Indiana University)." Total funding will be $11,990.

Daniel J. Sexton of Infectious Diseases has received a sub-award (1U01-CK000533-01) through Washington State University for a project entitled "Model-Driven Surveillance and Intervention Evaluation in Highly Stochastic Healthcare Settings." Total funding will be $130,040.

Kevin C. Oeffinger of Medical Oncology has received a sub-award through the Harvard Medical School for a project entitled "Improving Cancer Screening Guidelines for Survivors of Childhood Cancer." Total funding will be $14,798.

Mary H. Foster of Nephrology has received an award (1R01-ES027873-01) from the National Institutes of Health for a project entitled "Gene-Environment Collaboration in Autoimmune Disease." Total funding will be $1,800,638.

Laura P. Svetkey of Nephrology has received an award (1U54-MD012530-01) from the National Institutes of Health for a project entitled "Investigator Development Core," a part of Kimberly Johnson's project entitled "Duke Health Disparities Research Center."

Christopher Cox of Pulmonary, Allergy, and Critical Care Medicine has received an award (1U54-MD012530-01) from the National Institutes of Health for a project entitled "Research Project 3," a part of Kimberly Johnson's project entitled "Duke Health Disparities Research Center.”

Jennifer L. Ingram of Pulmonary, Allergy, and Critical Care Medicine has received an award (1R01-HL130234-01A1) from the National Institutes of Health for a project entitled "Mechanisms that Direct Airway Remodeling in Obese Asthma." Total funding will be $1,923,443.

David M. Murdoch of Pulmonary, Allergy, and Critical Care Medicine has received an award (3R01-GM123542-02S1) from the National Institutes of Health for a project entitled "Magnetically directed single cell transcriptome analysis in HIV latency." Total funding will be $48,200.

Loretta Que of Pulmonary, Allergy, and Critical Care Medicine has received a sub-award through the American Lung Association for a project entitled "COCO - Chronic Refractory Cough Cohort Study."

Industry-sponsored Clinical Trials

William S. Jones of Cardiology has received an award from Abbott Vascular Structural Heart for a project entitled "PORTICO JAPAN STUDY." Total funding will be $267,072.

Raymond J. Kim of Cardiology has received an award from Capricor Therapeutics, Inc. for a project entitled "ALLogeneic Heart STem Cells to Achieve Myocardial Regeneration." Total funding will be $28,352.

Renato D. Lopes of Cardiology has received an award from Pfizer, Inc. for a project entitled "Learning Lab: Pfizer South America Stroke Prevention." Total funding will be $39,900.

Renato D. Lopes of Cardiology has received an award from GlaxoSmithKline for a project entitled "ASCEND_protocol 205270." Total funding will be $522,750.

Renato D. Lopes of Cardiology has received an award from the GlaxoSmithKline for a project entitled "GSK-CKD program_CEC." Total funding will be $851,509.

Manesh R. Patel of Cardiology has received an award from ROX Medical for a project entitled "ROX HTN." Total funding will be $133,407.

Yubin Kang of Hematological Malignancies and Cellular Therapy has received an award from Incyte Corporation for a project entitled "Clinical characteristics, JAK2 status, and macrophage infiltration in multiple myeloma patients with marrow fibrosis." Total funding will be $100,020.

David Rizzieri of Hematological Malignancies and Cellular Therapy has received an award from Agios Pharmaceuticals, Inc. for a project entitled "A Phase 3, Multicenter, Double-Blind, Randomized, Placebo-Controlled Study of AG-120 in Combination with Azacitidine in Subjects 18 Years of Age with Previously Untreated Acute Myeloid Leukemia with an IDH1 Mutation." Total funding will be $362,184.

Thomas L. Ortel of Hematology has received an award from Stago for a project entitled "STA - Coag Control ABN PLUS Precision Study." Total funding will be $7,033.

Susanna Naggie of Infectious Diseases has received an award from AbbVie Inc. for a project entitled "M16-135." Total funding will be $81,305.

Daniel J. George of Medical Oncology has received an award from Bayer Healthcare Pharmaceuticals Inc for a project entitled "Bayer Prototype Prostate Program - 3 Day Programming." Total funding will be $75,205.

Shiaowen D. Hsu of Medical Oncology has received an award from Thunder Biotech for a project entitled "Targeting the TK1 receptor in colorectal and lung PDX using CarT cell and Motorcar cell." Total funding will be $242,697.

Neal E. Ready of Medical Oncology has received an award from AbbVie Inc. for a project entitled "A Phase 1/2 Study on the Safety of Rovalpituzumab Tesirine Administered in Combination with Nivolumab or Nivolumab and Ipilimumab for Adults with Extensive-Stage Small Cell Lung Cancer." Total funding will be $247,327.

Thomas Stinchcombe of Medical Oncology has received an award from Merck for a project entitled "A Phase III Randomized, Double-Blind, Placebo-controlled Trial of Pembrolizumab in Combination with Etoposide/Platinum (Cisplatin or Carboplatin) for the First-line Treatment of Subjects with Extensive Stage Small Cell Lung Cancer." Total funding will be $717,316.

Omar Mohamedaly of Pulmonary, Allergy, and Critical Care Medicine has received an award from Anthera Pharmaceuticals, Inc. for a project entitled "AN-EPI3333 RESULT." Total funding will be $279,053.

E. William St Clair of Rheumatology and Immunology has received an award from Bristol-Myers Squibb for a project entitled "BMS-IM101-603." Total funding will be $118,216.