New funding awards - September 2019

Tuesday, November 12, 2019

Sponsored Research

Paul Agris of Cardiology has received an award (W81XWH-16-1-0428) from the Department of Defense for a project entitled "Biochemical Consequences of Cdka I I Mutation that Result in Unprocessed, Nonfunctional Insulin and Type 2 Diabetes." Total funding will be $147,632.

John Alexander of Cardiology has received an award (2R18-FD005292-06) from the Food and Drug Administration for a project entitled "Increasing the Quality and Efficiency of Clinical Trials (U18)." Total funding will be $34,000,000.

Adam DeVore of Cardiology has received a sub-award (RCIP-1812-002) through the Vanderbilt University Medical Center for a project entitled "Operationalizing Patient-Reported Outcomes Measurement with Electronic Health Records in Patients with Heart Failure." Total funding will be $100,212.

Geoffrey Ginsburg of Cardiology has received an award (3U01-HG010225-02S2) from the National Institutes of Health for a project entitled "The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination." Total funding will be $1,500,000.

Geoffrey Ginsburg of Cardiology has received an award (3U01-HG010225-02S1) from the National Institutes of Health for a project entitled "The IGNITE II CC: Engagement, Coordination, Demonstration, and Dissemination." Total funding will be $131,975.

Adrian Hernandez of Cardiology has received an award (5U24-AT009676-03) from the National Institutes of Health for a project entitled "NIH Health Care Systems Research Collaboratory - Coordinating Center." Total funding will be $5,100,000.

Adrian Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "TO#2: PMO Workplan & Implementation - Amendment #3." Total funding will be $3,197,441.

Adrian Hernandez of Cardiology has received an award (3U24-AT009676-03S1) from the National Institutes of Health for a project entitled "NIH Health Care Systems Research Collaboratory - Training Supplement." Total funding will be $528,845.

Adrian Hernandez of Cardiology has received an award from the Patient-Centered Outcomes Research Institute for a project entitled "TO#1: CC Phase II Master Contract Leadership Mod 4." Total funding will be $115,755.

Francis Miller of Cardiology has received an award (W81XWH-16-1-0179) from the Department of Defense for a project entitled "Targeting Extracellular Histones with Novel RNA Biodrugs for the Treatment of Acute Lung Injury." Total funding will be $930,380.

Deepak Voora of Cardiology has received a sub-award (2R01-HL109568-05) through the Temple University for a project entitled "Human Platelet Defects in Transcription Factor RUNX1 Haplodeficiency." Total funding will be $16,915.

Jonathan Campbell of Endocrinology has received an award (1R01-DK123075-01) from the National Institutes of Health for a project entitled "Mechanisms of insulin secretion mediated by alpha cells." Total funding will be $1,888,381.

Diego Bohorquez of Gastroenterology has received an award (1R21-AT010818-01) from the National Institutes of Health for a project entitled "The efferent synapse in neuropod cells." Total funding will be $442,750.

Anna Mae Diehl of Gastroenterology has received an award (2R01-AA010154-24) from the National Institutes of Health for a project entitled "TNF Alpha and Recovery from Alcoholic Liver Injury." Total funding will be $2,478,051.

Anna Mae Diehl of Gastroenterology has received an award (2U01-DK061713-18) from the National Institutes of Health for a project entitled "Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN)." Total funding will be $511,403.

Lori Orlando of General Internal Medicine has received an award (3U01-HG010231-02S1) from the National Institutes of Health for a project entitled "Building and Deploying a Genomic-Medicine Risk Assessment Model for Diverse Primary Care Populations.." Total funding will be $2,967,476.

Cathleen Colon-Emeric of Geriatrics has received an award (3UH2-AG056925-03S1) from the National Institutes of Health for a project entitled "Physical Resiliencies: Indicators and Mechanisms in the Elderly Collaborative Administrative Supplement." Total funding will be $868,012.

Kenneth Lyles of Geriatrics has received a sub-award (1R01-AG059417-01A1Rev) through the California Pacific Medical Center for a project entitled "Prevention of Fractures in Patients with Parkinson's Disease Clinical Data Research Network (CDRN Admin)." Total funding will be $34,582.

Chris Woods of Infectious Diseases has received a sub-award () through the Institute for Medical Research, Inc. for a project entitled "IMR PSA: Sara Hoffman (CLOVER)." Total funding will be $20,641.

Gerard Blobe of Medical Oncology has received an award (1R01-CA226925-01A1) from the National Institutes of Health for a project entitled "Role of ALK4 in Regulating Receptor Trafficking and Pancreatic Cancer Biology." Total funding will be $2,079,628.

Kelly Marcom of Medical Oncology has received an award from the Johns Hopkins University for a project entitled "Translational Breast Cancer Research Consortium 2019 Infrastructure - SGK." Total funding will be $37,500.

Kelly Marcom of Medical Oncology has received an award from the Johns Hopkins University for a project entitled "Translational Breast Cancer Research Consortium 2019 Infrastructure (BCRF)." Total funding will be $37,500.

Andrew Nixon of Medical Oncology has received an award from the University of California - San Francisco for a project entitled "New strategies to improve drug development for carcinoid tumors." Total funding will be $77,397.

Pao-Hwa Lin of Nephrology has received an award from the University of Virginia - Charlottesville for a project entitled "MURDOCK Prevention CKD Pilot: Diet Microbiota, and Prevention of Chronic Kidney Disease (CKD)." Total funding will be $44,218.

Patty Lee of Pulmonary has received an award (7R01-HL138396-03) from the National Institutes of Health for a project entitled "TLR4-MEDIATED EPIGENETIC AND SENESCENCE MECHANISMS IN EMPHYSEMA." Total funding will be $618,162.

Megan Clowse of Rheumatology has received a sub-award (PPRN-1306-04811) through the Global Healthy Living Foundation for a project entitled "Pregnancies in women with Lupus in the Carolinas Collaborative (PLiCC) Cohort." Total funding will be $5,000.

Michael Hershfield of Rheumatology has received an award from the Orchard Therapeutics for a project entitled "Orchard Agreement." Total funding will be $200,000.

Kim Huffman of Rheumatology has received a sub-award (1R01-AG061378-01) through the Columbia University for a project entitled "Genomic Analysis of the CALERIE Trial to Generate New Knowledge for Geroscience." Total funding will be $373,704.

Industry-sponsored Clinical Trials

Kishan Parikh of Cardiology has received an award from Precision for Medicine for a project entitled "PAH trial of GB002." Total funding will be $85,529.

Eric Peterson of Cardiology has received an award from American College of Cardiology Foundation for a project entitled "TVT Registry Analytic Center Amendment 9." Total funding will be $420,164.

Jonathan Piccini of Cardiology has received an award from Philips Healthcare for a project entitled "MILES Study." Total funding will be $11,501.

Sudarshan Rajagopal of Cardiology has received an award from Analytics 4 Life for a project entitled "RADPH - Building a Repository of Phase Signals for Algorithm Development from Subjects with Pulmonary Hypertension.." Total funding will be $51,500.

Sreekanth Vemulapalli of Cardiology has received a sub-award (5U01-FD006292-02) through Medical Device Innovation Consortium for a project entitled "NeSTcc Test Case 6 Johnson and Johnson Certus device." Total funding will be $296,814.

Tracy Wang of Cardiology has received an award from AstraZeneca AB for a project entitled "Artemis Supplemental Analysis." Total funding will be $249,712.

Tracy Wang of Cardiology has received an award from St. Jude Medical Inc. for a project entitled "Patterns of Care in Mitral Regurgitation (AD-002)." Total funding will be $86,066.

Jonathan Campbell of Endocrinology has received an award from Eli Lilly and Company for a project entitled "ELI Lilly SRA." Total funding will be $320,000.

Manal Abdelmalek of Gastroenterology has received an award from Poxel S.A. for a project entitled "A randomized, double-blind, placebo-controlled, parallel group trial to assess the efficacy and safety of PXL770 versus placebo after 12 weeks of treatment in patients with Nonalcoholic Fatty Liver Disease (NAFLD) with or without type 2 diabetes." Total funding will be $139,314.

James Davis of General Internal Medicine has received a sub-award (HHSN261201400002B) through ICF International, Inc. for a project entitled "Implement SmokeFreeTXT eReferral Program into the Duke Smoking Cessation Program." Total funding will be $147,382.

Danielle Brander of Hematologic Malignancies and Cellular Therapy has received an award from BeiGene, Ltd for a project entitled "A Phase 3, Randomized study of Zanubrutinnig (BGB-3111) compared with Ibrutinig in Patients with Relapsed/Refractory Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma." Total funding will be $279,291.

Matthew McKinney of Hematologic Malignancies and Cellular Therapy has received an award from Nordic Nanovector ASA for a project entitled "LYMRIT 37-01." Total funding will be $275,948.

Jie Wang of Hematologic Malignancies and Cellular Therapy has received an award from MacroGenics, Inc. for a project entitled "A Phase I, First-in-Human, Open-Label, Dose Escalation Study of MGD013, A bispecific DART Protein binding PD-1 and LAG-3 in Patients with Unresectable or Metastatic Neoplasms." Total funding will be $258,144.

Ara Metjian of Hematology has received an award from Oscotec, Inc. for a project entitled "Phase II, of oral SKI-O-703 in Chronic Immune Thrombocytopenia (ITP)." Total funding will be $148,045.

Mehri McKellar of Infectious Diseases has received an award from Gilead Sciences, Inc. for a project entitled "GS - US - 380-5310." Total funding will be $127,986.

Cameron Wolfe of Infectious Diseases has received an award from Ansun BioPharma, Inc for a project entitled "DAS181-3-01." Total funding will be $98,829.

Ivy Altomare of Medical Oncology has received an award from Rigel Inc for a project entitled "A Phase 3, Multi-Center, Randomized, Double-Blind, Placebo-Controlled, Study of Fostamatinib Disodium in the Treatment of Warm Antibody Autoimmune Hemolytic Anemia." Total funding will be $48,102.

Jennifer Choe of Medical Oncology has received an award from Atara Biotherapeutics, Inc. for a project entitled "An Open-Label Phase 1B/2 Study to Evaluate the Safety and Efficacy of Tabelecleucel in Combination with Pembrolizumab in Subjects with Platinum-pretreated, Recurrent/Metastatic Epstein Barr Virus Associated Nasopharyngeal Carcinoma." Total funding will be $256,698.

Andrew Nixon of Medical Oncology has received a sub-award (75N91019D00024) through Leidos Biomedical Research, Inc. for a project entitled "Identification and validation of plasma-based protein biomarkers for cediranib and olaparib." Total funding will be $224,662.

John Strickler of Medical Oncology has received an award from Curegenix Inc. for a project entitled "A Phase 1 Open-label Dose Escalation and Dose Expansion Study of CGX1321 in Subjects with Advanced Solid Tumors and Phase 1b Study of CGX1321 in Combination with Pembrolizumab in Subjects with Advanced Gastrointestinal Tumors." Total funding will be $357,747.

Amber Oberle of Pulmonary has received an award from AstraZeneca Pharmaceuticals, LP for a project entitled "AZ CHINOOK D3250C00059 A Phase 4, Multicenter, Randomized, Double-blind, Parallel Group, Placebo-controlled Study to Evaluate the Effect of Benralizumab on Structural and Lung Function Changes in Severe Eosinophilic Asthmatics." Total funding will be $111,505.

Scott Palmer of Pulmonary has received an award from Bristol-Myers Squibb Company for a project entitled "Synthetic Control Arm for IPF." Total funding will be $220,739.

Robert Keenan of Rheumatology has received an award from Selecta Biosciences, Inc. for a project entitled "Selecta SEL 212/202." Total funding will be $176,400.

Teresa Tarrant of Rheumatology has received an award from AbbVie Inc. for a project entitled "Rheumatoid Arthritis ABBV-3373." Total funding will be $144,628.