New funding awards - September 2020

Tuesday, October 20, 2020

Sponsored Research

William Jones of Cardiology has received a sub-award () through the Vanderbilt University Medical Center for a project entitled "Advancement of PCORnet Infrastructure: Clinical Research Network Project." Total funding will be $240,198.

William Jones of Cardiology has received a sub-award (1R01-DK120598-01A1) through the Harvard Medical School for a project entitled "Medications and Weight Gain Across the Lifecourse in PCORnet." Total funding will be $7,849.

Rodger Liddle of Gastroenterology has received an award (1R01-DK124474-01A1) from the National Institutes of Health for a project entitled "Mechanisms of Pancreatic Fibrosis." Total funding will be $1,808,505.

Leigh Boulware of General Internal Medicine has received an award (1R01-DK127918-01) from the National Institutes of Health for a project entitled "Health system outreach to eliminate disparities in living kidney transplants." Total funding will be $5,926,967.

Leigh Boulware of General Internal Medicine has received an award (3UL1-TR002553-03S3) from the National Institutes of Health for a project entitled "Lancet Commission on Hearing Loss - CTSA Administrative Supplement." Total funding will be $859,137.

Kenneth Schmader of Geriatrics has received an award (75D30120F00018-Task 2) from the Centers for Disease Control and Prevention for a project entitled "CISA Shingrix 2020 Lead Site Task 2." Total funding will be $196,610.

Kenneth Schmader of Geriatrics has received an award (75D30120F00018-Task 1) from the Centers for Disease Control and Prevention for a project entitled "Lead Site Task 1: Simultaneous RZV and all V4 Vaccination (Lead)." Total funding will be $186,366.

Patrick Sullivan of Geriatrics has received an award (1R21-AG067340-01) from the National Institutes of Health for a project entitled "A Novel Animal Model of Late Onset Alzheimer's Disease." Total funding will be $442,750.

Lindsay Rein of Hematologic Malignancies and Cellular Therapy has received an award (W81XWH2010705) from the Department of Defense for a project entitled "Targeting beta-arrestins in myeloid malignancies." Total funding will be $579,600.

Cindy Pabon (Mentor: Brice Weinberg) of Hematology has received an award from the American Society of Hematology for a project entitled "The Role of Surface Immunoglobulin Isotype in Chronic Lymphocytic Leukemia Disease Biology and Clinical Outcomes in the Era of the Novel Agents." Total funding will be $6,000.

James White of Hematology has received an award (1R21-AG065943-01A1) from the National Institutes of Health for a project entitled "Assessing healthspan in aged mice after prolonged exposure to young circulation." Total funding will be $442,750.

Maria Blasi of Infectious Diseases has received an award (1R56-AI150359-01A1) from the National Institutes of Health for a project entitled "Targeting the HIV-1 reservoir with a combination of an IDLV-SIVGag therapeutic vaccine and Fc-engineered bnAbs (R01)." Total funding will be $760,086.

Matthew Rubach of Infectious Diseases has received an award (1R01-AI155733-01) from the National Institutes of Health for a project entitled "Sepsis Characterization in Kilimanjaro (R01)." Total funding will be $3,183,130.

Jennifer Freedman of Medical Oncology has received an award (1P20-CA251657-01) from the National Institutes of Health for a project entitled "Project 1: Race-related RNA splicing in non-small cell lung cancer: functional interrogation and therapeutic targeting, a part of Steven Patierno's project entitled "Duke Cancer Health Disparities P20 SPORE"." Total funding will be $0.

Steven Patierno of Medical Oncology has received an award (1P20-CA251657-01) from the National Institutes of Health for a project entitled "Administrative Core." Total funding will be $1,104,737.

Julie Steinbrink (Mentor: Xunrong Luo) of Nephrology has received an award from the American Society of Transplantation for a project entitled "Host Transcriptomic Responses to Non-Invasively Monitor the Inflammatory Response and Rejection Signals of Hepatitis-C Naive Recipients of Hepatitis-C Infected Donor Kidneys." Total funding will be $50,000.

Tomokazu Souma of Nephrology has received a sub-award (5P30-DK114857-03) through the Northwestern University for a project entitled "Elucidating molecular mechanisms of maladaptive renal repair." Total funding will be $31,997.

Deepshikha Ashana of Pulmonary has received an award from the American Thoracic Society for a project entitled "Trauma, conflict, and racial disparities in the intensive care unit." Total funding will be $25,000.

Christopher Cox of Pulmonary has received an award (5U01-AT009974-03S1) from the National Institutes of Health for a project entitled "Addressing psychological distress symptoms among serious illness survivors of a viral pandemic." Total funding will be $670,404.

Jennifer Ingram of Pulmonary has received an award (3R01-HL130234-04S1) from the National Institutes of Health for a project entitled "Mechanisms that Direct Airway Remodeling in Obese Asthma." Total funding will be $161,000.

Patty Lee of Pulmonary has received an award from the The Marcus Foundation for a project entitled "Targeting Health Care Provider (HCP) Burnout Crisis during COVID-19." Total funding will be $438,019.

Virginia Kraus of Rheumatology has received an award from the Arthritis Foundation for a project entitled "Site Charter Agreement for the Post-traumatic Osteoarthritis (PTOA) Platform Infrastructure Services (aka Site Research Readiness)." Total funding will be $310,670.

Industry-sponsored Clinical Trials

Adrian Hernandez of Cardiology has received a sub-award (HHSO100201700018C) through Janssen Pharmaceutica, Inc. for a project entitled "Janssen HERO Vaccine Trial Start Up Budget." Total funding will be $292,955.

William Herzog of Cardiology has received an award from American Regent for a project entitled "HEART-FID." Total funding will be $194,570.

Sreekanth Vemulapalli of Cardiology has received an award from American College of Cardiology Foundation for a project entitled "TVT Registry Analytic Center Amendment 11." Total funding will be $2,013,780.

Jennifer Rowell of Endocrinology has received an award from Eli Lilly and Company for a project entitled "The Effect of Tirzepatide versus Dulaglutide on Major Adverse Cardiovascular Events in Patients with Type 2 Diabetes (SURPASS-CVOT)." Total funding will be $596,260.

David Leiman of Gastroenterology has received an award from Phathom Pharmaceuticals, Inc. for a project entitled "A Phase 3 Randomized Multicenter Study to Evaluate the Efficacy and Safety of Open-Label Dual Therapy with Oral Vonoprazan 20 mg or Double-Blind Triple Therapy with Oral Vonoprazan 20 mg Compared to Double-Blind Triple Therapy with Oral Lansoprazole." Total funding will be $159,542.

Jane Onken of Gastroenterology has received an award from Arena Pharmaceuticals, Inc. for a project entitled "An Open-Label Extension Study of Etrasimod in Subjects with Moderately to Severely Active Ulcerative Colitis ELEVATE UC OLE: An Open-Label Extension Study for Treatment of Moderately to Severely Active Ulcerative Colitis." Total funding will be $628,910.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from ALX Oncology for a project entitled "ALX Oncology: I/II of ALX148 in combo with Aza in patients with higher risk MDS." Total funding will be $1,339,921.

Harry Erba of Hematologic Malignancies and Cellular Therapy has received an award from Forty Seven, Inc. for a project entitled "ENHANCE: A Randomized, Double-blind, Multicenter Study Comparing Magrolimab in Combination with Azacitidine versus Azacitidine Plus Placebo in Treatment-naive Patients with Higher Risk Myelodysplastic Syndrome." Total funding will be $269,615.

Lindsay Rein of Hematologic Malignancies and Cellular Therapy has received an award from CTI Biopharma Corp. for a project entitled "Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis." Total funding will be $204,818.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from Acrotech Biopharma for a project entitled "A Phase 2 Single Arm, Multicenter Trial to Evaluate the Efficacy of the CITE Antibody Blinatumomab (Blincyto) and Vincristine Sulfate Liposomal Injection (Marqibo) in Adult Subjects with Relapsed/Refractory Philadelphi8a Negative CD19+ Acute Lymphobe." Total funding will be $562,319.

David Rizzieri of Hematologic Malignancies and Cellular Therapy has received an award from Amgen, Inc. for a project entitled "Protocol Title: A Phase 2 Single Arm, Multicenter Trial to Evaluate the Efficacy of the BiTE® Antibody Blinatumomab (Blincyto) and vincristine sulfate liposomal injection (Marqibo) in Adult Subjects with Relapsed/Refractory Philadelphia Negative CD19." Total funding will be $402,703.

Chris Woods of Infectious Diseases has received a sub-award () through Abbott Rapid Diagnostics for a project entitled "Clinical Evaluation of the ID NOW¿ 1.1 COVID-19 Assay." Total funding will be $186,873.

Neal Ready of Medical Oncology has received an award from Merck Sharp & Dohme for a project entitled "A Phase 3 Study of Pembrolizumab (MK-3475) in Combination with Concurrent Chemoradiation Therapy Followed by Pembrolizumab with or without Olaparib vs Concurrent Chemoradiation Therapy Followed by Durvalumab in Participants with Unresectable, Locally." Total funding will be $639,824.

Jason Somarelli of Medical Oncology has received an award from FORMA Therapeutics, Inc. for a project entitled "Targeting Convergent Mechanisms of Therapy Resistance, Metastasis, and Immune Evasion with CBP inhibitors." Total funding will be $164,545.

John Reynolds of Pulmonary has received an award from BREATH Therapeutics for a project entitled "BT-L-CsA-302-DLT BOSTON-3." Total funding will be $249,646.

Momen Wahidi of Pulmonary has received an award from Biodesix for a project entitled "BDX-CD-003 Altitude: A multicenter randomized controlled trial prospectively evaluating the clnical utility of Nodify XL2 Proteomic Classifier in incendentally low to moderate risk lung nodules." Total funding will be $163,471.