Manal F. Abdelmalek, MD

Professor of Medicine
Campus mail 03119 Hosp South, Suite 03107, Room 03125, Durham, NC 27710
Phone (919) 684-3262
Email address manal.abdelmalek@duke.edu

My research interests include metabolic liver disease, particularly obesity-related liver disease and its association with complications of the insulin resistance syndrome. I am interested in studying the clinical, environmental, and genetic risk factors for nonalcoholic fatty liver disease, new therapeutic options for treatment, and evaluating the impact of NAFLD from a public health perspective.

In Their Words

Education and Training

  • Fellow in Gastroenterology, Medicine, Mayo School of Health Sciences, 1995 - 1998
  • Medical Resident, Medicine, Mayo School of Health Sciences, 1992 - 1995
  • M.D., University Missouri Kansas City, 1992

Publications

Newton, KP, Feldman, HS, Chambers, CD, Wilson, L, Behling, C, Clark, JM, Molleston, JP, Chalasani, N, Sanyal, AJ, Fishbein, MH, Lavine, JE, Schwimmer, JB, and Nonalcoholic Steatohepatitis Clinical Research Network (NASH CRN), . "Low and High Birth Weights Are Risk Factors for Nonalcoholic Fatty Liver Disease in Children." The Journal of pediatrics 187 (August 2017): 141-146.e1.

PMID
28366357
Full Text

Kappus, M, and Abdelmalek, M. "De Novo and Recurrence of Nonalcoholic Steatohepatitis After Liver Transplantation." Clinics in liver disease 21, no. 2 (May 2017): 321-335. (Review)

PMID
28364816
Full Text

Patel, YA, Henao, R, Moylan, CA, Guy, CD, Piercy, DL, Diehl, AM, and Abdelmalek, MF. "Reply to Kim et al." The American journal of gastroenterology 112, no. 5 (May 2017): 807-808.

PMID
28469220
Full Text

Yang, JD, Abdelmalek, MF, Guy, CD, Gill, RM, Lavine, JE, Yates, K, Klair, J, Terrault, NA, Clark, JM, Unalp-Arida, A, Diehl, AM, Suzuki, A, and Nonalcoholic Steatohepatitis Clinical Research Network, . "Patient Sex, Reproductive Status, and Synthetic Hormone Use Associate With Histologic Severity of Nonalcoholic Steatohepatitis." Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 15, no. 1 (January 2017): 127-131.e2.

PMID
27523635
Full Text

Nelson, JE, Handa, P, Aouizerat, B, Wilson, L, Vemulakonda, LA, Yeh, MM, Kowdley, KV, and NASH Clinical Research Network, . "Increased parenchymal damage and steatohepatitis in Caucasian non-alcoholic fatty liver disease patients with common IL1B and IL6 polymorphisms." Alimentary pharmacology & therapeutics 44, no. 11-12 (December 2016): 1253-1264.

PMID
27730688
Full Text

Abdelmalek, MF. "NAFLD: The clinical and economic burden of NAFLD: time to turn the tide." Nature reviews. Gastroenterology & hepatology 13, no. 12 (December 2016): 685-686.

PMID
27826139
Full Text

Patel, YA, Henao, R, Moylan, CA, Guy, CD, Piercy, DL, Diehl, AM, and Abdelmalek, MF. "Vitamin D is Not Associated With Severity in NAFLD: Results of a Paired Clinical and Gene Expression Profile Analysis." The American journal of gastroenterology 111, no. 11 (November 2016): 1591-1598.

PMID
27644736
Full Text

Corey, KE, Yates, KP, Abdelmalek, MF, Sanyal, AJ, Tetri, BA, Kowdley, KV, Cummings, O, Tonascia, J, and Chalasani, NP. "Longitudinal relationship between changes in liver histology and renal function in adults with NASH: The NASH Clinical Research Network Experience." October 2016.

Scholars@Duke

Patel, YA, Henao, R, Moylan, CA, Guy, CD, Piercy, DL, Diehl, AM, and Abdelmalek, MF. "Vitamin D is Not Associated with Histologic Severity in NAFLD: Results of a Paired Clinical and Hepatic Gene Expression Profile Analysis." October 2016.

Scholars@Duke

Suzuki, A, Spencer, HJ, Moylan, CA, Dranoff, JA, Abdelmalek, MF, Guy, CD, and Diehl, AM. "Hepatic estrogen transcriptional activity and estrogen receptor a gene expression are negatively correlated with fibrosis stage in patients with nonalcoholic fatty liver disease (NAFLD)." October 2016.

Scholars@Duke

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