Erik Magnus Ohman, MBBS

Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 7403 Duke North, Durham, NC 27710
Phone (919) 681-2069
Email address ohman001@mc.duke.edu

The main focus of my research is in the management of acute myocardial infarction. My focus has revolved around the use of interventional procedures such as balloon angioplasty, intra-aortic balloon pumping and other support devices for the management of patients with acute myocardial infarction. Through participating and designing a number of randomized trials, we have helped crystallize the management to sustain patency of the infarct-related coronary artery in acute myocardial infarction. Furthermore, I have conducted several large multi-center clinical trials on the use of intra-aortic counterpulsation and angioplasty to better understand the pathophysiology of interventional procedures. Another major focus has been in the area of risk stratification in acute myocardial infarction. Early observations done abroad have led me to use new cardiac markers to identify high and low risk patients. Further research in this area will integrate early and rapid triage along with monitoring of the effect of thrombolysis after reperfusion in patients. A patent in the latter category has already been issued. My continued focus in the performance of multi-center international clinical trials has allowed us to explore different treatment strategies for the management of acute myocardial infarction from an international prospective. We have also collected angioplasty data on nearly 6,000 patients from around North America to further explore international differences in the management of patients using percutaneous interventions.

In Their Words

Education and Training

  • M.B.B.S., Royal College of Surgeons (Ireland), 1981

Publications

Ohman, EM. "Secondary prevention shifts into second gear." Lancet (London, England) (November 10, 2017).

PMID
29132878
Full Text

Brener, SJ, Mehran, R, Dangas, GD, Ohman, EM, Witzenbichler, B, Zhang, Y, Parvataneni, R, and Stone, GW. "Relation of Baseline Hemoglobin Levels and Adverse Events in Patients With Acute Coronary Syndromes (from the Acute Catheterization and Urgent Intervention Triage strategY and Harmonizing Outcomes with RevasculariZatiON and Stents in Acute Myocardial Infarction Trials)." The American journal of cardiology 119, no. 11 (June 2017): 1710-1716.

PMID
28388994
Full Text

Ohman, EM, Roe, MT, Steg, PG, James, SK, Povsic, TJ, White, J, Rockhold, F, Plotnikov, A, Mundl, H, Strony, J, Sun, X, Husted, S, Tendera, M, Montalescot, G, Bahit, MC, Ardissino, D, Bueno, H, Claeys, MJ, Nicolau, JC, Cornel, JH, Goto, S, Kiss, RG, Güray, Ü, Park, D-W, Bode, C, Welsh, RC, and Gibson, CM. "Clinically significant bleeding with low-dose rivaroxaban versus aspirin, in addition to P2Y12 inhibition, in acute coronary syndromes (GEMINI-ACS-1): a double-blind, multicentre, randomised trial." Lancet (London, England) 389, no. 10081 (May 2017): 1799-1808.

PMID
28325638
Full Text

Ohman, EM. "Redefining the Gold Standard of Myocardial Infarction Using Troponin T." Clinical chemistry 63, no. 1 (January 2017): 429-430. (Review)

PMID
27811205
Full Text

Melloni, C, Cornel, JH, Hafley, G, Neely, ML, Clemmensen, P, Zamoryakhin, D, Prabhakaran, D, White, HD, Fox, KA, Ohman, EM, Armstrong, PW, and Roe, MT. "Impact of chronic kidney disease on long-term ischemic and bleeding outcomes in medically managed patients with acute coronary syndromes: Insights from the TRILOGY ACS Trial." European heart journal. Acute cardiovascular care 5, no. 6 (October 1, 2016): 443-454.

Scholars@Duke

Ohman, EM, Douglas, PS, Dean, LB, and Ginsburg, GS. "Philanthropy for Science: Is It a Viable Option?." Circulation research 119, no. 10 (October 2016): 1057-1059.

PMID
27789583
Full Text

Kong, DF, and Ohman, EM. "Chronic Total Coronary Occlusions, Percutaneous Coronary Intervention, and Mortality: A "Hybrid Approach" to Interpretation." JACC. Cardiovascular interventions 9, no. 15 (August 2016): 1545-1547.

PMID
27491604
Full Text

Cohen, MG, and Ohman, EM. "Should the Benefit of Transradial Access Still Be Questioned?." JACC. Cardiovascular interventions 9, no. 9 (May 2016): 908-910.

PMID
27151606
Full Text

Hess, PL, Wojdyla, DM, Al-Khatib, SM, Lokhnygina, Y, Wallentin, L, Armstrong, PW, Roe, MT, Ohman, EM, Harrington, RA, Alexander, JH, White, HD, Van de Werf, F, Piccini, JP, Held, C, Aylward, PE, Moliterno, DJ, Mahaffey, KW, and Tricoci, P. "Sudden Cardiac Death After Non-ST-Segment Elevation Acute Coronary Syndrome." JAMA cardiology 1, no. 1 (April 2016): 73-79.

PMID
27437658
Full Text

Levine, GN, Bates, ER, Blankenship, JC, Bailey, SR, Bittl, JA, Cercek, B, Chambers, CE, Ellis, SG, Guyton, RA, Hollenberg, SM, Khot, UN, Lange, RA, Mauri, L, Mehran, R, Moussa, ID, Mukherjee, D, Ting, HH, O'Gara, PT, Kushner, FG, Ascheim, DD, Brindis, RG, Casey, DE, Chung, MK, de Lemos, JA, Diercks, DB, Fang, JC, Franklin, BA, Granger, CB, Krumholz, HM, Linderbaum, JA, Morrow, DA, Newby, LK, Ornato, JP, Ou, N, Radford, MJ, Tamis-Holland, JE, Tommaso, CL, Tracy, CM, Woo, YJ, and Zhao, DX. "2015 ACC/AHA/SCAI Focused Update on Primary Percutaneous Coronary Intervention for Patients With ST-Elevation Myocardial Infarction: An Update of the 2011 ACCF/AHA/SCAI Guideline for Percutaneous Coronary Intervention and the 2013 ACCF/AHA Guideline for the Management of ST-Elevation Myocardial Infarction: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Society for Cardiovascular Angiography and Interventions." Circulation 133, no. 11 (March 2016): 1135-1147.

PMID
26490017
Full Text

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