Matthew A. Sparks, MD

Assistant Professor of Medicine
Campus mail 2 Genome Court, Msrb2 Room 1013, Box_103015, Durham, NC 27710
Phone (919) 684-9737
Email address matthew.sparks@duke.edu

My lab is interested in understanding how both the renin angiotensin and prostanoid systems regulate blood pressure by altering blood flow to the kidney. My lab utilizes a combination of physiologic and molecular techniques in genetically modified mice to probe questions about how changes in the micro circulation in the kidney alter sodium excretion. The overarching goal of this research is to identify novel mechanisms to target drug therapy for patients with hypertension. My research is funded by a career development award from the Department of Veterans Affairs Office of Research and Development (IK2BX002240) and a Scientist Development Grant from the American Heart Association. In my role as Director of Undergraduate Medical Research in the Department of Medicine I help promote research in the Department of Medicine during the 3rd year of medical school at Duke University. I also serve as the Associate Program Director for the Nephrology Fellowship Program.

I'm also interested finding ways to promote medical education. My focus is on leveraging social media to enhance learning in nephrology. I am a faculty member of the Nephrology Social Media Collective (NSMC) and member of the online nephrology journal club (NephJC). I am also co-founder and advisory board member of the first nephrology blog associated with a journal- AJKD blog, the official blog of the American Journal of Kidney Diseases. Co-creator of the popular edutainment project NephMadness. Past deputy editor of Renal Fellow Network where I continue to remain an advocate for the site and author the yearly “Top Nephrology Stories of the Year”. I am currently a member of the Communications and Media Committee of the American Society of Nephrology, the American Heart Association and am a fellow of the American Society of Nephrology and the National Kidney Foundation.

I serve as Education Director for KIDNEYcon- a yearly hands-on conference dedicated to advances in nephrology held in Little Rock, AR each April.

@Nephro_Sparks on Twitter

Nephrology Fellowship Program

Education and Training

  • Fellow in Nephrology, Medicine, Duke University School of Medicine, 2007 - 2011
  • Chief Resident, Medicine, University of Arkansas for Medical Sciences College of Medicine, 2006 - 2007
  • Resident, Medicine, University of Arkansas for Medical Sciences College of Medicine, 2003 - 2006
  • M.D., University of Arkansas for Medical Sciences College of Medicine, 2003

Publications

Wolf, E, Diaz, EJ, Hollis, AN, Hoang, TA, Azad, HA, Bendt, KM, Griffiths, RC, and Sparks, MA. "Vascular type 1 angiotensin receptors control blood pressure by augmenting peripheral vascular resistance in female mice." American Journal of Physiology Renal Physiology 315, no. 4 (October 2018): F997-F1005.

PMID
29897266
Full Text

Carlson, DA, Singer, MR, Sutherland, C, Redondo, C, Alexander, LT, Hughes, PF, Knapp, S, Gurley, SB, Sparks, MA, MacDonald, JA, and Haystead, TAJ. "Targeting Pim Kinases and DAPK3 to Control Hypertension." Cell Chemical Biology 25, no. 10 (October 2018): 1195-1207.e32.

PMID
30033129
Full Text

Farouk, S, and Sparks, MA. "Renal Fellow Network: Past and Future." Clinical Journal of the American Society of Nephrology : Cjasn (September 14, 2018).

PMID
30217899
Full Text

Colbert, GB, Topf, J, Jhaveri, KD, Oates, T, Rheault, MN, Shah, S, Hiremath, S, and Sparks, MA. "The Social Media Revolution in Nephrology Education." Kidney International Reports 3, no. 3 (May 2018): 519-529. (Review)

PMID
29854960
Full Text

Singh, H, Sparks, MA, and Haller, H. "Thrombotic microangiopathies." In Nephrology Secrets: Fourth Edition, 283-286. March 30, 2018.

Full Text

Lerma, EV, Sparks, MA, and Topf, JM. Nephrology Secrets: Fourth Edition. March 30, 2018.

Scholars@Duke

Lerma, EV, Sparks, MA, and Topf, JM. Preface. March 30, 2018.

Full Text

Lerma, EV, Sparks, MA, and Topf, J. Nephrology Secrets. March 30, 2018.

Scholars@Duke

Wolf, E, Kothari, NR, Roberts, JK, and Sparks, MA. "Baclofen Toxicity in Kidney Disease." American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation 71, no. 2 (February 2018): 275-280.

PMID
28899601
Full Text

Sparks, MA, and Topf, JM. "NephMadness After 5 Years: A Recap and Game Plan for the Future." American journal of kidney diseases : the official journal of the National Kidney Foundation (January 4, 2018).

PMID
29325760
Full Text

Pages