Medicine Grand Rounds | Duke Department of Medicine

Medicine Grand Rounds (MGR) is a weekly seminar series to support the academic environment of the Duke Department of Medicine. Topics and speakers are selected to provide faculty and trainees with up-to-date knowledge about timely issues in internal medicine. MGR occurs every Friday at 8 a.m in Duke North 2002 unless otherwise noted below.

How to Connect to Medicine Grand Rounds (MGR)

Faculty and trainees should use this Zoom link to join each week:

Meeting ID: 912 2757 9393
Passcode: 393431
Dial by Phone: +1 301 715 8592

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Continuing Medical Education Credits

CME	MOC-ABIM
Physician Credit - Duke Continuing Education designates Medicine Grand Rounds and Duke Medicine Learning, Education, and Discussion Series (LEADS) activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity. Physicians must attend the CME activity, must have an active ETHOS account, and must text their attendance (with the weekly text code) to 919-213-8033 starting at 8:00am and must do so within 24 hours. GME Trainees are not eligible for CME credit. The referenced media source is missing and needs to be re-embedded.	Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to one (1) MOC credit in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

CME

MOC-ABIM

Physician Credit - Duke Continuing Education designates Medicine Grand Rounds and Duke Medicine Learning, Education, and Discussion Series (LEADS) activity for a maximum of 1.0 AMA PRA Category 1 Credit(s)TM. Physicians should only claim credit commensurate with the extent of their participation in the activity. Physicians must attend the CME activity, must have an active ETHOS account, and must text their attendance (with the weekly text code) to 919-213-8033 starting at 8:00am and must do so within 24 hours. GME Trainees are not eligible for CME credit.

The referenced media source is missing and needs to be re-embedded.

Successful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to one (1) MOC credit in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

2023-2024 Upcoming Medicine Grand Round Lectures

Date	Presenter	Title	Learning Objectives
3/1/24	Duke Internal Medicine Residents & Duke Faculty	2024 Faculty vs Trainee Annual Trivia Bowl (In-person only)	Review knowledge of rare medical diseases Support collaboration amongst trainees in advancing medical education and Facilitate networking and camaraderie between medicine faculty and residents
3/8/24	Nicoleta Economou-Zavlanos, PhD & Michael Pencina, PhD	Unlocking the Potential of Trustworthy AI in Healthcare	Understand pitfalls of artificial intelligence and machine learning for health Understand core principles of trustworthy AI for healthcare Understand how ethical and quality principles can be implemented through governance and oversight Understand national efforts on trustworthy AI for health Watch the Presentation
3/15/24	Katherine Garman, MD, Associate Professor of Medicine, Division of Gastroenterology	Mentoring: Evidence-Based Reflections	Review the evidence around the importance of strong effective mentoring in medicine Discuss the importance of mentoring in the context of Equity, Diversity, and Inclusion Review effective strategies for mentors to support mentees Review effective strategies for mentees within the mentoring relationship Watch the Presentation
3/22/24	Donald P. McDonnell Professor of Medicine, Division of Endocrinology, Metabolism, and Nutrition	Evolution of Endocrine Therapies for Breast and Prostate Cancer	Question the longstanding objective of developing interventions that achieve absolute inhibition of estrogen and androgen action as a therapeutic approach in patients with breast and prostate cancer (respectively) Differentiate contemporary estrogen receptor modulators at the level of their mechanism of action and how this impacts their clinical use in breast cancer Differentiate contemporary androgen receptor modulators at the level of their mechanism of action and how this impacts their clinical use in prostate cancer Watch the Presentation
3/29/24	Mitchell T. Heflin, MD, MHS, Professor of Medicine, Division of Geriatrics Associate Dean for Interprofessional Education and Care (IPEC)	IPE @ Duke: Building Our Competency and Capacity for Collaboration	Describe the evidence supporting interprofessional collaborative practice (IPCP) Define core competencies for interprofessional education (IPE) List facilitators and barriers to implementation of IPE Identify opportunities for preparing a “collaboration-ready” workforce Watch the Presentation
4/5/24	Polly E. Parsons MD, President and CEO, AAIM. E. L. Amidon Chair and Professor of Medicine Emerita, UVM - VIRTUAL PRESENTATION VIA ZOOM	The Evolution of Academic Medicine: Career Challenges and Opportunities	Explain the evolution of academic medicine Evaluate the impact of changes in academic medicine on careers Discover that career paths can be non-linear Watch the Presentation
4/12/24	Camille Frazier-Mills, MH, MHS, Professor of Medicine, Cardiology	Syncope: A health system approach to evaluation and management	Review guidelines for the evaluation and management of the recurrent syncope patient Review health system data in syncope evaluation Discuss areas of improvement in the evaluation and management of recurrent syncope Watch the Presentation
4/19/24	William E (Bill) Kraus, Distinguished Professor, Division of Cardiology	Duke Cardiac Rehabilitation: Origins, Rich History and Victories in Caring for Our Patients after Cardiac Procedures and Events	Understand the history of cardiac rehabilitation and its importance to Duke Cardiology history Understand the four clinical components of cardiac rehabilitation -- secondary prevention of cardiac events -- and the importance for preventing adverse outcomes after cardiac events and procedures Understand the referral criteria for cardiac rehabilitation and how to make a referral Understand the barriers for patient participation in cardiac rehabilitation Watch the Presentation
4/26/24	Genevieve G. R. Embree, MD, MPH, Assistant Professor of Medicine, Division of General Internal Medicine	Public Health within a Health Care System	Gain a greater appreciation for the role of population health management within Primary Care Share a new model for increasing cancer screening rates Understand the role of partnerships with community-based organizations to improve patients' health outcomes Consider the value of tightening the intersection between public health and health care systems Watch the Presentation
5/3/24	Neil L. Spector Art of Medicine Award Medicine Grand Rounds Christopher E. Cox Professor of Medicine, Division of Pulmonary, Allergy, and Critical Care Medicine	It is Always Possible	Understand different approaches to mentoring based on the differing needs of unique individuals Consider the tradeoffs of experiencial stasis vs. dynamic innovation in mentoring Reflect on how lucky we are to get to do what we do

2023-2024 Medicine Grand Round Recordings

Date	Presenter	Title	Learning Objectives
07/07/23	Chris Beyrer, MD, MPH Professor of Medicine, Infectious Diseases Director, Duke Global Health Institute (DGHI)	Global Health: Advancing Equity Through Science	Understand the role of health equity in global health Review the research, teaching, and service opportunities available to Duke faculty at the Global Health Institute Watch the recording
07/14/23	Svati Shah, MD, MHS Ursula Geller Distinguished Professor of Research in Cardiovascular Diseases Professor of Medicine, Cardiology Professor of Biostatistics and Bioinformatics, Basic Science Departments Anisha Chandiramani, MD Assistant Professor of Medicine, General Internal Medicine Duke Department of Medicine	Enabling Precision Medicine through Collaboration	Understand the principles of precision medicine, including the role of genomics, AI and implementation science to improve patient care Discuss a new genomic medicine program at Duke University, discussing potential scientific output, benefits, challenges, and ethical considerations Discuss strategies for integrating precision medicine into clinical practice and improving patient outcomes through a new Duke collaboration with a data science company Watch the recording
07/21/23	David Casarett,MD Professor of Medicine, General Internal Medicine Section Chief of Palliative Care, General Internal Medicine Duke Department of Medicine	How Duke Health is Using Design Thinking to Promote Goal-Concordant Care for All Patients	Define goal-concordant care Explain obstacles to achieving goal-concordant care in advanced serious illness Describe how design thinking can promote behavior change Watch the recording
07/28/23	Ilan Schwartz,MD, PhD Associate Professor of Medicine, Infectious Diseases Duke Department of Medicine	Brave New World: Promise and Peril of Generative AI in Medicine	Define generative artificial intelligence, language models, and chatbots Describe promising use cases for language models to improve work flows in clinical medicine Describe limitations of current language models that make them poorly suited for some tasks in medicine Watch the recording
8/4/23	2023 Joseph C Greenfield Visiting Professor Martha Gulati, MD, MS, FACC, FAHA, FASPC, FESC Director of Preventative Cardiology at the Smidt Heart Institute Associate Director of the Barbara Streisand Women's Heart Center Cedars-Sinai Medical Center, Los Angeles, CA	Understanding Sex Differences in Cardiovascular Disease	Address the persistent sex-specific gaps found in guidelines, recommendations and prevention of cardiovascular disease strategies for women, and recognize diagnostic and therapeutic adherence Understand the differences in coronary artery disease patterns in women and its impact on prognosis Recognize sex-specific risk factors that affect women that should be part of risk assessment of women Watch the Recording
08/11/23	Sudarshan Rajagopal, MD, PhD Associate Professor of Medicine, Cardiology Duke Department of Medicine Associate Professor of Cell Biology and Biochemistry, Basic Science Departments	Pulmonary Hypertension: From Bench to Bedside	Gain knowledge about the various clinical definitions and classification systems used to categorize pulmonary hypertension Explore the underlying pathologic processes contributing to the development of pulmonary hypertension Discuss potential therapeutic targets related to receptor signaling in PH Understand the advantages, limitations, and potential future directions of advanced imaging techniques for improving the diagnosis, monitoring, and management of pulmonary hypertension Watch the Recording
08/18/23	Susan L. Murray, MD Medical Instructor, Department of Medicine, Nephrology Duke Department of Medicine	Lies, Damned Lies and Statistics: Medicine in the Age of Alternative Facts (This lecture is approved for 200-level RCR credit. To receive credit, attendance must be for the entire 60 minute event.)	State the historical context of data manipulation in medicine Explain some of the challenges facing us in today's research Describe future challenges to research integrity Watch the Recording
08/25/23	Kathleen Cooney, MD Chair, Department of Medicine	Fireside Chat	Watch the Recording
09/01/23	No Medicine Grand Rounds
09/08/23	Dr. Gene Nichol Professor of Law, University of North Carolina at Chapel Hill	Poverty and Equal Dignity in North Carolina	The challenges of intense poverty and economic marginalization in one of the most economically vibrant states of the richest nation on earth, the richest and most unequal nation in human history Listen to the Recording
09/15/23	Chetan B. Patel, MD Associate Professor of Medicine, Cardiology Duke Department of Medicine	Heart Transplant at Duke: Tradition and Innovation	Help audience understand donor and recipient limitations in heart transplantation Describe the framework utilized for overcoming these limitations at our institution and how we are providing advanced heart therapies to more patients in need Understand the potential for new science in heart transplantation Watch the Recording
09/22/23	Danielle M. Brander, MD Assistant Professor of Medicine, Hematologic Malignancies and Cellular Therapy, Duke Department of Medicine	Chronic Lymphocytic Leukemia in 2023	Understand the heterogeneity of CLL/SLL in diagnosis, disease course, and treatment outcomes, and the factors that contribute to high risk CLL/SLL Contrast available treatment options for patients in the frontline and relapsed setting Recognize common toxicities of BTK inhibitors and venetoclax and describe strategies to mitigate and manage these side effects Identify remaining areas of unmet need for patients with CLL/SLL and Richter's Transformation Watch the Recording
09/29/23	Robert M. Tighe, MD Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care Medicine Duke Department of Medicine	Climate Change and Health as Viewed Through the Prism of the Impacts of Air Pollution	Broadly define the impact of climate change and human health Define sources and health effects of air pollution Define mechanisms of susceptibility of air pollution Watch the Recording
10/6/23	Christina E. Barkauskas, MD Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care Medicine Duke Department of Medicine	Building Momentum for Clinical Trials in the Duke MICU	To learn of the clinical trials conducted in the Duke MICU during the COVID-19 pandemic To understand the landscape of upcoming observational studies to phenotype patients with ARDS, pneumonia, and sepsis To understand the challenges surrounding and solutions for consenting critically ill patients to clinical trials To see how serendipity can play a role in the career of a physician in academic medicine. Watch the Recording
10/20/23	Keynote Speaker: John Duronville, MD Assistant Professor of Medicine, Nephrology Faculty Leader, Stepping In 4 Respect Duke University School of Medicine Guest Speakers: Margaret Plews-Ogan, MD Annie E. and Bernard B. Brodie Professor of Medicine, UVA School of Medicine, Co-Director, Wisdom and Wellbeing Program, UVA Health Co-Founder and Co-PI, Stepping in for Respect National Collaborative, University of Virginia Gregory Clarke Townsend, MD Associate Professor of Internal Medicine, Division of Infectious Diseases and International Health, Associate Dean for Diversity, and Medical Education, UVA School of Medicine, Co-Developer of Stepping In 4 Respect, University of Virginia	Phillips-Winn Memorial Lecture Stepping In 4 Respect: Upstander Training Nationally and at Duke University	Understand the importance of Upstander intervention in the academic/medical work environment Gain insight on the incidents of bias and disrespect in the medical environment both at Duke and nationally Learn how Stepping In 4 Respect training is utilized to promote a culture of respect and inclusion Review the Presentation
10/27/23	Michael Hershfield, MD Professor of Medicine & Biochemistry, Rheumatology and Immunology Duke Department of Medicine John Sundy, MD Adjunct Professor in the Department of Medicine	The Path to Pegloticase for Refractory Gout - Intrapreneurial Drug Development at Duke	To appreciate the clinical consequences of inadequately treated chronic gout To understand the potential advantages and disadvantages of replacement therapy with PEGylated enzymes To review the development of PEG-enzyme therapy for two disorders of purine metabolism To appreciate opportunities for translational laboratory-based research at Duke Watch the Recording
11/03/23	Megan E.B. Clowse, MD Associate Professor of Medicine, Division of Rheumatology and Immunology	Confronting new (and old) challenges in pregnancy prevention & planning with women living with chronic medical conditions	Identify women with lupus at risk for catastrophic pregnancies Gain skills that promote honest & accurate conversations about pregnancy prevention and planning Watch the Recording
11/10/23	Manesh R. Patel, MD Richard S. Stack Distinguished Professor of Medicine, Chief, Division of Cardiology, Director Duke Heart Center	Eugene A. Stead Jr. Memorial Lecture Antithrombotic therapy and Vascular disease management: Moving towards precision CV care and the Duke Databank 3.0	Understand the Mechanism of Action of Current Anti-Thrombotic Therapies including oral anticoagulants, Factor X and Factor XI inhibitors Understand the risk and benefits of anti-thrombotic therapy in patients with atrial fibrillation Understand the various data sources that will provide precision care to patients with cardiovascular disease Watch the Recording
11/17/23	Christopher J. Hostler, MD, MPH Assistant Professor of Medicine, Division of Infectious Diseases, Associate Vice Chair for Veterans Affairs, Department of Medicine Anna L. Rutherford, MD Interim Deputy Chief of Staff Durham VA Medical Center Meryl Severson, MD Associate Professor, Neurosurgery Michael Dore, MD Assistant Professor of Medicine, General Internal Medicine	Veterans Experience Grand Rounds	Dr. Hostler Understand ways to discuss issues unique to veterans Learn ways to forge a deeper connection with veteran patients Develop an understanding of the experiences our veterans face while in service Understand the issues our veterans face when returning home from deployment or leaving service Dr. Rutherford To engage the learner with personal stories and lessons learned to create an improved awareness of military medicine and culture Dr. Severson Understand the concept of Echelons of Care Understand the concept of Battlefield Triage and Tactical Combat Casualty Care (TCCC) Understand the most common cause of battlefield trauma deaths Dr. Dore Discuss military culture and how it can affect healthcare Watch the Presentation
12/1/23	Laura Caputo, MD Assistant Professor of Medicine, Department of Medicine, Division of General Internal Medicine	VA Hospitalists in Medical Education: A MODEL Approach	Review the current status of faculty development within VA hospital medicine Introduce Project MODEL and its role in supporting a geographically diverse group of clinicians with common goals Classify what we’ve learned about the VA hospitalist teaching experience and their relationships with medical education and academic affiliates Explore potential future directions for faculty development in medical education in the VHA Watch the Presentation
1/12/24	Gary Bennett, PhD Dean, Trinity College of Arts & Sciences, Duke University Professor, Department of Psychology and Neuroscience Research Professor, Duke Global Health Institute Associate Professor, Duke Department of Medicine, Division of Nephrology Professor, Duke School of Nursing	You Have to Keep Moving Forward: Obesity in High-Risk Populations	Recall the descriptive and social epidemiology of obesity among U.S. high risk populations Evaluate the empirical evidence on obesity interventions deployed among obesity high risk populations. Appraise promising obesity treatment options for high risk populations Watch the Presentation
1/19/24	James Davis, MD Associate Professor of Medicine, Department of Medicine, Division of General Internal Medicine	Contemporary Tobacco Treatment Pharmacotherapy	Provide overview of current tobacco use in the US Provide an overview of neurobiological processes central to tobacco addiction Provide an overview of contemporary pharmacotherapy strategies used for tobacco use Watch the Presentation
1/26/24	Diego Bohórquez, PhD Associate Professor of Medicine, Division of Gastroenterology	Deciphering Visceral Instincts	Define neuropods Discuss the neural basis of intestinal sensations Understand the neural basis of sugar preferences
2/2/24	Amanda Marie Eudy, PhD Assistant Professor in Medicine, Division of Rheumatology and Immunology	The Type 1 & 2 SLE Model: A new model of care for systemic lupus erythematosus	Understand the patient-rheumatologist discordance in lupus Introduce the Type 1 & 2 SLE Model Describe the rationale for using the Type 1 and Type 2 in clinical care and research setting Watch the Presentation
2/16/24	Richard Riedel, MD Associate Professor of Medicine, Division of Medical Oncology	Making Progress in a Rare Disease: An Update on Sarcoma Management	Recognize the heterogeneity and increased complexity of sarcoma management Review data supporting current decision making for patients in select histological subtypes Highlight emerging therapeutic approaches in specific disease states Introduce available clinical trials at Duke Watch the Presentation
2/23/24	Trevor Sytsma, MS3 Allison Chu, MS3 Eleanor Seo, MS2	Rooted Together: Students Bridging Partnerships to Tackle SDOH in Durham	Identify key local resources for learning about the unique needs and assets of Durham County Understand Root Causes as one of many Duke medical student-run organizations focused on community-engaged work Learn tangible ways to partner with and leverage the strengths of students rotating on Medicine services who engage in community-facing programs addressing SDOH Watch the Presentation