Afreen Idris Shariff, MBBS

Assistant Professor of Medicine
Member of the Duke Cancer Institute

During my training at Duke, I developed a keen interest in understanding more about novel cancer therapies and its effect on the endocrine system. I currently see patients with patients with general endocrine disorders and focus heavily on immunotherapy associated endocrinopathies. I work specifically in the areas of streamlined and evidence based clinical care in collaboration with oncology. My research involves identifying factors that predispose patients to develop these immune related adverse events.
In addition, I focus on outcomes of patients with diabetes who belong to different ethnic groups, specifically South Asians. I like to put culture in the center of the discussion when discussing lifestyle changes with patients. This makes it easier and more acceptable for patients to incorporate lifestyle changes which are critical in managing diabetes effectively.

Education and Training

  • Fellowship in Endocrinology, Metabolism and Nutrition, Medicine, Duke University School of Medicine, 2015 - 2017
  • Internal Medicine Residency, The Brody School of Medicine at East Carolina University, 2011 - 2014
  • M.B.B.S., University of Hyderabad (India), 2008

Publications

Shariff, Afreen Idris, Sohail Syed, Rebecca A. Shelby, Jeremy Force, Jeffrey Melson Clarke, David D’Alessio, and Leonor Corsino. “Novel cancer therapies and their association with diabetes..” J Mol Endocrinol 62, no. 2 (February 1, 2019): R187–99. https://doi.org/10.1530/JME-18-0002.

PMID
30532995
Full Text

Herbst, Rebecca, Wilburn Bolton, Afreen Shariff, and Jennifer B. Green. “Cardiovascular Outcome Trial Update in Diabetes: New Evidence, Remaining Questions..” Curr Diab Rep 17, no. 9 (September 2017). https://doi.org/10.1007/s11892-017-0898-8.

PMID
28726152
Full Text

Misaghian-Xanthos, Negin, Afreen I. Shariff, Kavya Mekala, Loretta R. Fearrington, Tracy L. Setji, Joseph A. Aloi, and John B. Buse. “Sodium-Glucose Cotransporter 2 Inhibitors and Diabetic Ketoacidosis: A Case Series From Three Academic Institutions..” Diabetes Care 40, no. 6 (June 2017): e65–66. https://doi.org/10.2337/dc16-2591.

PMID
28351898
Full Text

Shariff, A. I., L. Gratian, and J. Perkins. “A rare presentation of TSH secreting pituitary macroadenoma with coexisting primary hypothyroidism from Hashimoto’s thyroiditis.” In The Art of Neuroendocrinology: A Case-Based Approach to Medical Decision-Making, 35–44, 2017.

Scholars@Duke

Desai, Tejas, Vibhu Dhingra, Afreen Shariff, Aabid Shariff, Edgar Lerma, Parteek Singla, Swapnil Kachare, et al. “Quantifying the Twitter Influence of Third Party Commercial Entities versus Healthcare Providers in Thirteen Medical Conferences from 2011 - 2013..” In Plos One, Vol. 11, 2016. https://doi.org/10.1371/journal.pone.0162376.

PMID
27668433
Full Text

Shariff, Afreen Idris, Jennifer Laura Stahl, and Fiona J. Cook. “An Instructive Case of Hyperemesis Gravidarum, Wernicke's Encephalopathy, and Primary Hyperparathyroidism.” In Endocrine Reviews, Vol. 35. ENDOCRINE SOC, 2014.

Scholars@Duke

Shariff, Afreen I., Xiangming Fang, and Tejas Desai. “Using social media to create a professional network between physician-trainees and the American Society of Nephrology..” Adv Chronic Kidney Dis 20, no. 4 (July 2013): 357–63. https://doi.org/10.1053/j.ackd.2013.03.005.

PMID
23809288
Full Text

Desai, Tejas, Afreen Shariff, Vibhu Dhingra, Deeba Minhas, Megan Eure, and Mark Kats. “Is content really king? An objective analysis of the public's response to medical videos on YouTube..” Plos One 8, no. 12 (2013). https://doi.org/10.1371/journal.pone.0082469.

PMID
24367517
Full Text

Desai, Tejas, Afreen Shariff, Aabid Shariff, Mark Kats, Xiangming Fang, Cynthia Christiano, and Maria Ferris. “Tweeting the meeting: an in-depth analysis of Twitter activity at Kidney Week 2011..” Plos One 7, no. 7 (2012). https://doi.org/10.1371/journal.pone.0040253.

PMID
22792254
Full Text

Rajkumar, R., A. I. Shariff, J. -. I. Choi, G. T. Huang, K. V. Pandit, J. C. Sembrat, D. C. Ishizawar, et al. “Integration of Genome-Wide MicroRNA and mRNA Expression Profiles in Pulmonary Arterial Hypertension and Pulmonary Hypertension Associated with Idiopathic Pulmonary Fibrosis.” Circulation 124:A15511, no. 21 (November 22, 2011).

Scholars@Duke