Afreen Idris Shariff, MBBS

Assistant Professor of Medicine
Member of the Duke Cancer Institute

Afreen Shariff, MD is an endocrinologist with expertise in endocrine disease in cancer patients. She is the Director of the Duke Endo-Oncology Program and an Associate Director for the Cancer Therapy Toxicity Program at the Duke Center for Cancer Immunotherapy. She holds a faculty appointment as an Assistant Professor of Medicine in the Division of Endocrinology, Diabetes and Metabolism at Duke University School of Medicine.

Dr. Shariff completed her medical school in India from Deccan College of Medical Sciences, Internal Medicine training from East Carolina University’s Brody School of Medicine and fellowship in Endocrinology from Duke University School of Medicine. Her clinical work and research is focused on high value care for endocrine disease in cancer patients.

She also chairs the Oncoendocrinology Special Interest Group (SIG) with the Endocrine Society and influences global networking, clinical practice and education in the field of Oncoendocrinology. At Duke, Dr. Shariff's work includes developing interdisciplinary partnerships, creating the clinical infrastructure and framework needed for AI assisted clinical decision making to improve access and coordinated care for patients with cancer therapy related toxicities. She also hosts and produces the podcast series Checkpoint NOW that emphasizes shared decision making between oncologists and subspecialists

Education and Training

  • Fellowship in Endocrinology, Metabolism and Nutrition, Medicine, Duke University School of Medicine, 2015 - 2017
  • Internal Medicine Residency, East Carolina University, Brody School of Medicine, 2011 - 2014
  • M.B.B.S., University of Hyderabad (India), 2008

Publications

Lee, T., M. Hu, Q. Gao, J. Amason, D. Borkar, D. D’Alessio, M. Canos, A. Shariff, M. Pajic, and M. Hadziahmetovic. “Evaluation of a deep learning supported remote diagnosis model for identification of diabetic retinopathy using wide-field Optomap.” Annals of Eye Science 7 (June 1, 2022). https://doi.org/10.21037/aes-21-53.

Full Text

Atiq, Saad, Nathan Hirshman, Afreen Shariff, and Tian Zhang. “The management of toxicities from immune, targeted and ADCs treatments in patients with urothelial cancer.” Urol Oncol, December 30, 2021. https://doi.org/10.1016/j.urolonc.2021.10.002.

PMID
34973855
Full Text

Anders, Carey K., Nicole R. LeBoeuf, Lara Bashoura, Saadia A. Faiz, Afreen I. Shariff, and Alexandra Thomas. “What's the Price? Toxicities of Targeted Therapies in Breast Cancer Care.” Am Soc Clin Oncol Educ Book 40 (May 2020): 55–70. https://doi.org/10.1200/EDBK_279465.

PMID
32421449
Full Text

Merrill, Jennifer D., Diana Soliman, Nitya Kumar, Sooyoung Lim, Afreen I. Shariff, and William S. Yancy. “Low-Carbohydrate and Very-Low-Carbohydrate Diets in Patients With Diabetes.” Diabetes Spectr 33, no. 2 (May 2020): 133–42. https://doi.org/10.2337/ds19-0070.

PMID
32425450
Full Text

Stahl, Jennifer, Niki Winters, and Afreen Shariff. “A RARE CASE OF PRIMARY HYPERPARATHYROIDISM, HYPEREMESIS GRAVIDARUM, AND WERNICKE ENCEPHALOPATHY.” Aace Clin Case Rep 5, no. 2 (March 2019): e108–11. https://doi.org/10.4158/ACCR-2018-0286.

PMID
31967013
Full Text

Shariff, Afreen Idris, Sohail Syed, Rebecca A. Shelby, Jeremy Force, Jeffrey Melson Clarke, David D’Alessio, and Leonor Corsino. “Novel cancer therapies and their association with diabetes.” J Mol Endocrinol 62, no. 2 (February 1, 2019): R187–99. https://doi.org/10.1530/JME-18-0002.

PMID
30532995
Full Text

Herbst, Rebecca, Wilburn Bolton, Afreen Shariff, and Jennifer B. Green. “Cardiovascular Outcome Trial Update in Diabetes: New Evidence, Remaining Questions.” Curr Diab Rep 17, no. 9 (September 2017): 67. https://doi.org/10.1007/s11892-017-0898-8.

PMID
28726152
Full Text

Misaghian-Xanthos, Negin, Afreen I. Shariff, Kavya Mekala, Loretta R. Fearrington, Tracy L. Setji, Joseph A. Aloi, and John B. Buse. “Sodium-Glucose Cotransporter 2 Inhibitors and Diabetic Ketoacidosis: A Case Series From Three Academic Institutions.” Diabetes Care 40, no. 6 (June 2017): e65–66. https://doi.org/10.2337/dc16-2591.

PMID
28351898
Full Text

Shariff, A. I., L. Gratian, and J. Perkins. “A Rare Presentation of TSH Secreting Pituitary Macroadenoma with Coexisting Primary Hypothyroidism from Hashimoto’s Thyroiditis.” In The Art of Neuroendocrinology: A Case-Based Approach to Medical Decision-Making, edited by L. Blevins, Jr. Nova Science Pub Inc, 2017.

Scholars@Duke

Pages