Hematologic Malignancies and Cellular Therapy

Anthony D Sung, MD

Associate Professor of Medicine
Member of the Duke Cancer Institute
Senior Fellow in the Center for the Study of Aging and Human Development
Campus mail Box 3961 Med Ctr, Durham, NC 27710
Phone (919) 668-1000
Email address anthony.sung@duke.edu

I am dedicated to the treatment of hematologic malignancies through cellular therapies such as hematopoietic stem cell transplantation (HCT). My research focuses on strategies to reduce complications of HCT and ranges from preclinical studies using murine models of HCT to Phase 1 and Phase 2 clinical trials. Areas of interest include the role of the microbiota (the trillions of bacteria living in and on our bodies), nutrition, and exercise in modulating HCT outcomes such as graft-versus-host disease (GVHD) and infections. In addition to advancing new pharmacological and cellular immunotherapies in support of these goals, we also are developing mobile health technologies (mHealth) to monitor patients at home, both as part of our innovative home transplant program as well as to improve follow up care of all our patients when they return home after transplant.

In Their Words

Education and Training

  • Fellowship, Hematology Oncology, Duke University School of Medicine, 2011 - 2014
  • Residency, Osler Medical Housestaff Training Program, Johns Hopkins University School of Medicine, 2008 - 2011
  • M.D., Harvard University , 2008

Grants

Publications

Smith, Patrick J., Meagan Lew, Yen Lowder, Kristi Romero, Jillian C. Thompson, Lauren Bohannon, Alyssa Pittman, et al. “Cognitive impairment in candidates for allogeneic hematopoietic stem cell transplantation.” In Bone Marrow Transplant, 57:89–94, 2022. https://doi.org/10.1038/s41409-021-01470-z.

PMID
34667271
Full Text

Zhao, Aaron T., and Anthony D. Sung. “Pitfalls and Successes in Trials in Older Transplant Patients with Hematologic Malignancies.” Curr Oncol Rep 24, no. 1 (January 2022): 125–33. https://doi.org/10.1007/s11912-022-01194-3.

PMID
35061190
Full Text

Lin, Chenyu, Laura Morrison, Edwin Alyea, Taewoong Choi, Cristina Gasparetto, Gwynn Long, Richard Lopez, et al. “Allogeneic Stem Cell Transplantation with Omidubicel: Long-Term Follow-Up from a Single Center.” American Society of Hematology, 2021.

Scholars@Duke

Smith, Sophia K., Tamara J. Somers, Eric Kuhn, Eric Laber, Anthony D. Sung, Karen L. Syrjala, Bryan Feger, et al. “A SMART approach to optimizing delivery of an mHealth intervention among cancer survivors with posttraumatic stress symptoms.” Contemp Clin Trials 110 (November 2021): 106569. https://doi.org/10.1016/j.cct.2021.106569.

PMID
34536584
Full Text

Muhsen, Ibrahim N., Omar W. Rasheed, Eiad A. Habib, Rakan K. Alsaad, Mohannad K. Maghrabi, Md A. Rahman, Douglas Sicker, et al. “Current status and future perspectives on the Internet of Things in oncology.” Hematol Oncol Stem Cell Ther, October 18, 2021. https://doi.org/10.1016/j.hemonc.2021.09.003.

PMID
34687614
Full Text

Tarnasky, Aaron M., George N. Tran, Jonathan Nicolla, Fred A. P. Friedman, Steven Wolf, Jesse D. Troy, Anthony D. Sung, et al. “Mobile Application to Identify Cancer Treatment-Related Financial Assistance: Results of a Randomized Controlled Trial.” Jco Oncol Pract 17, no. 10 (October 2021): e1440–49. https://doi.org/10.1200/OP.20.00757.

PMID
33797952
Full Text

Islam, Prioty, Helen Tang, Haesu Jin, Felicia Cao, Lauren M. Bohannon, Yi Ren, Nelson J. Chao, et al. “Female Sex Is Associated with Improved Long-Term Survival Following Allogeneic Hematopoietic Stem Cell Transplantation.” Transplant Cell Ther 27, no. 9 (September 2021): 784.e1-784.e7. https://doi.org/10.1016/j.jtct.2021.06.012.

PMID
34146734
Full Text

Liu, JoAnn, Deborah Hutch Allen, Martha Lassiter, Felicia Cao, Anthony D. Sung, and Nelson J. Chao. “Homecare Encounters: An Organizational Response to Innovative Care for Patients Undergoing Hematopoietic Stem Cell Transplantation During COVID-19.” Clin J Oncol Nurs 25, no. 4 (August 1, 2021): 457–64. https://doi.org/10.1188/21.CJON.457-464.

PMID
34269347
Full Text

Bohannon, Lauren, Helen Tang, Kristin Page, Yi Ren, Sin-Ho Jung, Alexandra Artica, Anne Britt, et al. “Decreased Mortality in 1-Year Survivors of Umbilical Cord Blood Transplant vs. Matched Related or Matched Unrelated Donor Transplant in Patients with Hematologic Malignancies.” Transplant Cell Ther 27, no. 8 (August 2021): 669.e1-669.e8. https://doi.org/10.1016/j.jtct.2021.05.002.

PMID
33991725
Full Text

Mishra, Asmita, Jaime M. Preussler, Vijaya Raj Bhatt, Christopher Bredeson, Saurabh Chhabra, Anita D’Souza, Parastoo B. Dahi, et al. “Breaking the Age Barrier: Physicians' Perceptions of Candidacy for Allogeneic Hematopoietic Cell Transplantation in Older Adults.” Transplant Cell Ther 27, no. 7 (July 2021): 617.e1-617.e7. https://doi.org/10.1016/j.jtct.2021.03.028.

PMID
33836312
Full Text

Pages