Daniel Christopher Parker, MD

Assistant Professor of Medicine
Assistant Professor in Neurology
Senior Fellow of the Center for the Study of Aging and Human Development
Campus mail Rm 1510 Blue Zone Duke South, Box 3003, Durham, NC 27705
Phone (919) 660-7692
Email address daniel.parker@duke.edu

Biological aging is the greatest risk factor for most chronic diseases, including frailty and dementia. The geroscience hypothesis posits that interventions that target aspects of biological aging may delay or prevent many of these diseases simultaneously. My research centers on understanding the mechanisms of interventions that affect biological aging, like exercise training and caloric restriction and using that understanding to develop therapies that maintain cognitive and physical function in older adults.

Education and Training

  • Post-Doctoral Research Fellowship, Duke Center For The Study Of Aging And Human Development, Duke University School of Medicine, 2017 - 2019
  • Internal Medicine Residency, Eastern Virginia Medical School, 2013 - 2016
  • Advanced Fellowship in Geriatric Medicine, Medicine, ,, 0018
  • M.D., Eastern Virginia Medical School, 2013

Publications

Erickson, Melissa L., Will Wang, Julie Counts, Leanne M. Redman, Daniel Parker, Janet L. Huebner, Jessilyn Dunn, and William E. Kraus. “Field-Based Assessments of Behavioral Patterns During Shiftwork in Police Academy Trainees Using Wearable Technology.” J Biol Rhythms, April 13, 2022, 7487304221087068. https://doi.org/10.1177/07487304221087068.

PMID
35416084
Full Text

Parker, Daniel C., Ma Wan, Kurt Lohman, Li Hou, Anh Tram Nguyen, Jingzhong Ding, Alain Bertoni, et al. “Monocyte miRNAs Are Associated With Type 2 Diabetes.” Diabetes 71, no. 4 (April 1, 2022): 853–61. https://doi.org/10.2337/db21-0704.

PMID
35073575
Full Text

Eckhoff, Austin M., Ashton A. Connor, Julie K. M. Thacker, Dan G. Blazer, Harvey G. Moore, Randall P. Scheri, Sandhya A. Lagoo-Deenadayalan, et al. “A Multidimensional Bioinformatic Platform for the Study of Human Response to Surgery.” Ann Surg, March 3, 2022. https://doi.org/10.1097/SLA.0000000000005429.

PMID
35258509
Full Text

Huffman, Kim M., Daniel C. Parker, Manjushri Bhapkar, Susan B. Racette, Corby K. Martin, Leanne M. Redman, Sai Krupa Das, et al. “Calorie restriction improves lipid-related emerging cardiometabolic risk factors in healthy adults without obesity: Distinct influences of BMI and sex from CALERIE™ a multicentre, phase 2, randomised controlled trial.” Eclinicalmedicine 43 (January 2022): 101261. https://doi.org/10.1016/j.eclinm.2021.101261.

PMID
35028547
Full Text

Whitson, Heather E., Donna Crabtree, Carl F. Pieper, Christine Ha, Sandra Au, Miles Berger, Harvey J. Cohen, et al. “A template for physical resilience research in older adults: Methods of the PRIME-KNEE study.” J Am Geriatr Soc 69, no. 11 (November 2021): 3232–41. https://doi.org/10.1111/jgs.17384.

PMID
34325481
Full Text

Parker, D., K. M. Huffman, D. W. Belsky, V. Kraus, J. Huebner, and W. Kraus. “Aerobic exercise training decreases multi-indicator, physiology-based measures of biological aging.” In Journal of the American Geriatrics Society, 69:S182–83, 2021.

Scholars@Duke

Mitchell, C., M. Morey, R. Sloane, D. Parker, H. Cohen, and K. Hall. “Two-Year Changes in Physical Activity Domains Across the Lifespan: Impact of Age and Gender.” In Journal of the American Geriatrics Society, 69:S102–S102, 2021.

Scholars@Duke

Ramalingam, Sendhilnathan, Sharareh Siamakpour-Reihani, Lauren Bohannan, Yi Ren, Alexander Sibley, Jeff Sheng, Li Ma, et al. “A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant.” Plos One 16, no. 6 (2021): e0252995. https://doi.org/10.1371/journal.pone.0252995.

PMID
34170918
Full Text

Parker, Daniel C., Cathleen Colόn-Emeric, Janet L. Huebner, Ching-Heng Chou, Virginia Byers Kraus, Carl F. Pieper, Richard Sloane, et al. “Biomarkers Associated with Physical Resilience After Hip Fracture.” J Gerontol a Biol Sci Med Sci 75, no. 10 (September 25, 2020): e166–72. https://doi.org/10.1093/gerona/glaa119.

PMID
32386291
Full Text

Parker, Daniel C., Bryce N. Bartlett, Harvey J. Cohen, Gerda Fillenbaum, Janet L. Huebner, Virginia Byers Kraus, Carl Pieper, and Daniel W. Belsky. “Association of Blood Chemistry Quantifications of Biological Aging With Disability and Mortality in Older Adults.” J Gerontol a Biol Sci Med Sci 75, no. 9 (September 16, 2020): 1671–79. https://doi.org/10.1093/gerona/glz219.

PMID
31693736
Full Text

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