David Bruce Bartlett, PhD

Medical Instructor in the Department of Medicine
Member of the Duke Cancer Institute
Member of Duke Molecular Physiology Institute
Campus mail 300 North Duke Street, Carmichael Building, Room 50-111, Durham, NC 27701
Phone (919) 684-0622
Email address david.bartlett@duke.edu

David Bartlett is an Instructor in the Department of Medicine, Division of Medical Oncology. He earned his PhD in Immunology from the University of Birmingham, England where he specialized in the effects of exercise and lifestyles on immune function and systemic inflammation in the elderly. He was awarded a coveted Marie Curie Outgoing Fellowship from the European Union which brought him to Duke under the guidance of William Kraus, MD where he assessed the immunological and physiological responses of exercise training in patients with prediabetes and rheumatoid arthritis. His laboratory studies the effects of exercise and energy balance on immune function and physiology of patient groups including cancer, arthritis and diabetes. His research program is focused on human studies employing a wide range of techniques including human physiological testing such as cardiopulmonary fitness assessment, exercise training to in vitro and ex vivo cellular assays. 

Education and Training

  • Ph.D., University of Birmingham, 2014

Publications

Hanson, ED, Danson, E, Nguyen-Robertson, CV, Fyfe, JJ, Stepto, NK, Bartlett, DB, and Sakkal, S. "Maximal exercise increases mucosal associated invariant T cell frequency and number in healthy young men." European journal of applied physiology 117, no. 11 (November 2017): 2159-2169.

PMID
28864849
Full Text

McNee, G, Eales, KL, Wei, W, Williams, DS, Barkhuizen, A, Bartlett, DB, Essex, S, Anandram, S, Filer, A, Moss, PAH, Pratt, G, Basu, S, Davies, CC, and Tennant, DA. "Citrullination of histone H3 drives IL-6 production by bone marrow mesenchymal stem cells in MGUS and multiple myeloma." Leukemia 31, no. 2 (February 2017): 373-381.

PMID
27400413
Full Text

Bartlett, DB, Slentz, CA, Connelly, MA, Piner, LW, Willis, LH, Bateman, LA, Granville, EO, Bales, CW, Huffman, KM, and Kraus, WE. "Association of the Composite Inflammatory Biomarker GlycA, with Exercise-Induced Changes in Body Habitus in Men and Women with Prediabetes." Oxidative medicine and cellular longevity 2017 (January 2017): 5608287-.

PMID
28642810
Full Text

Bartlett, DB, Shepherd, SO, Wilson, OJ, Adlan, AM, Wagenmakers, AJM, Shaw, CS, and Lord, JM. "Neutrophil and Monocyte Bactericidal Responses to 10 Weeks of Low-Volume High-Intensity Interval or Moderate-Intensity Continuous Training in Sedentary Adults." Oxidative medicine and cellular longevity 2017 (January 2017): 8148742-.

PMID
28656073
Full Text

Bartlett, DB, and Huffman, KM. "Lifestyle Interventions to Improve Immunesenescence." In The Ageing Immune System and Health. Springer, October 18, 2016. (Chapter)

Full Text

Bartlett, DB, Fox, O, McNulty, CL, Greenwood, HL, Murphy, L, Sapey, E, Goodman, M, Crabtree, N, Thøgersen-Ntoumani, C, Fisher, JP, Wagenmakers, AJM, and Lord, JM. "Habitual physical activity is associated with the maintenance of neutrophil migratory dynamics in healthy older adults." Brain, behavior, and immunity 56 (August 2016): 12-20.

PMID
26928196
Full Text

Bartlett, DB, Connelly, MA, AbouAssi, H, Bateman, LA, Tune, KN, Huebner, JL, Kraus, VB, Winegar, DA, Otvos, JD, Kraus, WE, and Huffman, KM. "A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls." Arthritis research & therapy 18 (April 2016): 86-.

PMID
27067270
Full Text

Vitlic, A, Lord, JM, Taylor, AE, Arlt, W, Bartlett, DB, Rossi, A, Arora-Duggal, N, Welham, A, Heald, M, Oliver, C, Carroll, D, and Phillips, AC. "Neutrophil function in young and old caregivers." British journal of health psychology 21, no. 1 (February 2016): 173-189.

PMID
26285690
Full Text

Ludwig, C, Williams, DS, Bartlett, DB, Essex, SJ, McNee, G, Allwood, JW, Jewell, E, Barkhuisen, A, Parry, H, Anandram, S, Nicolson, P, Gardener, C, Seymour, F, Basu, S, Dunn, WB, Moss, PAH, Pratt, G, and Tennant, DA. "Alterations in bone marrow metabolism are an early and consistent feature during the development of MGUS and multiple myeloma." Blood cancer journal 5 (January 2015): e359-. (Letter)

PMID
26473531
Full Text

Baylis, D, Ntani, G, Edwards, MH, Syddall, HE, Bartlett, DB, Dennison, EM, Martin-Ruiz, C, von Zglinicki, T, Kuh, D, Lord, JM, Aihie Sayer, A, and Cooper, C. "Inflammation, telomere length, and grip strength: a 10-year longitudinal study." Calcified tissue international 95, no. 1 (July 2014): 54-63.

PMID
24858709
Full Text

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