David S. Caldwell, MD

Associate Professor of Medicine
Campus mail 014 Baker House, Durham, NC 27710
Phone (919) 684-8844
Email address caldw009@mc.duke.edu

Our current efforts are a continuation of our research evaluating the utility of congnitive behavioral methods for assessing and treating pain. Ultimately it is our hope to help patients more effectively cope with long term demands of chronic and disabling pain due to both rheumatoid arthritis and osteoarthritis.

Our current research in osteoarthritis is to examine physiological and psychological responses to noxious stimuli in men and women with osteoarthritis. We hope to learn more about differences in pain perception in men vs. women as well as any racial difference that may exist. In addition, we hope to learn more specifically the possible mechanism of these gender differences in individuals with osteoarthritis.

Patients with RA are faced with the task of coping with numerous major life stresses associated with their disease and often experience emotional distress related to disruptions in their health, work, family and marital functioning. With recognition of the psychosocial effects of RA has come increased interest in psychosocial approaches to treatment. The long range goal of our research here is to reduce the pain, psychological disability, and physical disability experienced by patients having rheumatoid arthritis. The study underway continues our research on psychosocial interventions for arthritis and is designed to test the hypothesis that a clinician - assisted emotional disclosure protocol can improve the long term functional status of patients with RA.

Education and Training

  • M.D., Wake Forest University, 1971

Publications

Van Denburg, AN, Shelby, RA, Caldwell, DS, O'Sullivan, ML, and Keefe, FJ. "Self-Efficacy for Pain Communication Moderates the Relation Between Ambivalence Over Emotional Expression and Pain Catastrophizing Among Patients With Osteoarthritis." The Journal of Pain : Official Journal of the American Pain Society 19, no. 9 (September 2018): 1006-1014.

PMID
29631037
Full Text

Lefebvre, JC, Jensen, MP, Waters, SJ, Molton, IR, Keefe, FJ, and Caldwell, DS. "The development and assessment of the Worry About Pain Questionnaire." European journal of pain (London, England) 21, no. 7 (August 2017): 1154-1164.

PMID
28230331
Full Text

Huebner, JL, Landerman, LR, Somers, TJ, Keefe, FJ, Guilak, F, Blumenthal, JA, Caldwell, DS, and Kraus, VB. "Exploratory secondary analyses of a cognitive-behavioral intervention for knee osteoarthritis demonstrate reduction in biomarkers of adipocyte inflammation." Osteoarthritis and cartilage 24, no. 9 (September 2016): 1528-1534.

PMID
27090577
Full Text

Broderick, JE, Keefe, FJ, Schneider, S, Junghaenel, DU, Bruckenthal, P, Schwartz, JE, Kaell, AT, Caldwell, DS, McKee, D, and Gould, E. "Cognitive behavioral therapy for chronic pain is effective, but for whom?." Pain 157, no. 9 (September 2016): 2115-2123.

PMID
27227692
Full Text

Rini, C, Porter, LS, Somers, TJ, McKee, DC, DeVellis, RF, Smith, M, Winkel, G, Ahern, DK, Goldman, R, Stiller, JL, Mariani, C, Patterson, C, Jordan, JM, Caldwell, DS, and Keefe, FJ. "Automated Internet-based pain coping skills training to manage osteoarthritis pain: a randomized controlled trial." Pain 156, no. 5 (May 2015): 837-848.

PMID
25734997
Full Text

Caldwell, DS. "North Carolina medical legacy." North Carolina medical journal 76, no. 2 (April 2015): 126-. (Letter)

PMID
25856363
Scholars@Duke

Broderick, JE, Keefe, FJ, Bruckenthal, P, Junghaenel, DU, Schneider, S, Schwartz, JE, Kaell, AT, Caldwell, DS, McKee, D, Reed, S, and Gould, E. "Nurse practitioners can effectively deliver pain coping skills training to osteoarthritis patients with chronic pain: A randomized, controlled trial." Pain 155, no. 9 (September 2014): 1743-1754.

PMID
24865795
Full Text

Somers, TJ, Wren, AA, Blumenthal, JA, Caldwell, D, Huffman, KM, and Keefe, FJ. "Pain, physical functioning, and overeating in obese rheumatoid arthritis patients: do thoughts about pain and eating matter?." Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases 20, no. 5 (August 2014): 244-250.

PMID
25036564
Full Text

Broderick, JE, Keefe, FJ, Bruckenthal, P, Junghaenel, DU, Schneider, S, Schwartz, JE, Kaell, AT, Caldwell, DS, McKee, D, Reed, S, and Gould, E. "Nurse practitioners can effectively deliver pain coping skills training to osteoarthritis patients with chronic pain: A randomized, controlled trial." Pain 155, no. 9 (January 1, 2014): 1743-1754.

Full Text

Somers, TJ, Blumenthal, JA, Guilak, F, Kraus, VB, Schmitt, DO, Babyak, MA, Craighead, LW, Caldwell, DS, Rice, JR, McKee, DC, Shelby, RA, Campbell, LC, Pells, JJ, Sims, EL, Queen, R, Carson, JW, Connelly, M, Dixon, KE, Lacaille, LJ, Huebner, JL, Rejeski, WJ, and Keefe, FJ. "Pain coping skills training and lifestyle behavioral weight management in patients with knee osteoarthritis: a randomized controlled study." Pain 153, no. 6 (June 2012): 1199-1209.

PMID
22503223
Full Text

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