Education and Training
- Resident, Internal Medicine, Icahn School of Medicine at Mount Sinai, 2003 - 2005
- Intern, Internal Medicine, Icahn School of Medicine at Mount Sinai, 2002 - 2003
- M.D., Thomas Jefferson University, 2002
Yu, Samuel Mon-Wei, Pierre-Yves Jean-Charles, Dennis M. Abraham, Suneet Kaur, Clarice Gareri, Lan Mao, Howard A. Rockman, and Sudha K. Shenoy. “The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling..” J Biol Chem 294, no. 7 (February 15, 2019): 2500–2518. https://doi.org/10.1074/jbc.RA118.004926.
Abraham, Dennis M., Teresa E. Lee, Lewis J. Watson, Lan Mao, Gurangad Chandok, Hong-Gang Wang, Stephan Frangakis, et al. “The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction..” The Journal of Clinical Investigation 128, no. 11 (November 2018): 4843–55. https://doi.org/10.1172/JCI95945.
Hershberger, Kathleen A., Dennis M. Abraham, Juan Liu, Jason W. Locasale, Paul A. Grimsrud, and Matthew D. Hirschey. “Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload..” The Journal of Biological Chemistry 293, no. 27 (July 2018): 10630–45. https://doi.org/10.1074/jbc.ra118.002187.
Toth, Krisztian, Lauren M. Slosky, Thomas F. Pack, Nikhil M. Urs, Peter Boone, Lan Mao, Dennis Abraham, Marc G. Caron, and Lawrence S. Barak. “Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2..” Synapse (New York, N.Y.) 72, no. 1 (January 2018). https://doi.org/10.1002/syn.22012.
Hershberger, Kathleen A., Dennis M. Abraham, Angelical S. Martin, Lan Mao, Juan Liu, Hongbo Gu, Jason W. Locasale, and Matthew D. Hirschey. “Sirtuin 5 is required for mouse survival in response to cardiac pressure overload..” The Journal of Biological Chemistry 292, no. 48 (December 2017): 19767–81. https://doi.org/10.1074/jbc.M117.809897.
Jean-Charles, Pierre-Yves, Samuel Mon-Wei Yu, Dennis Abraham, Reddy Peera Kommaddi, Lan Mao, Ryan T. Strachan, Zhu-Shan Zhang, et al. “Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling..” Jci Insight 2, no. 17 (September 7, 2017). https://doi.org/10.1172/jci.insight.95998.
Martin, Angelical S., Dennis M. Abraham, Kathleen A. Hershberger, Dhaval P. Bhatt, Lan Mao, Huaxia Cui, Juan Liu, et al. “Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy model..” Jci Insight 2, no. 14 (July 20, 2017). https://doi.org/10.1172/jci.insight.93885.
Abraham, Dennis M., Robert T. Davis, Chad M. Warren, Lan Mao, Beata M. Wolska, R John Solaro, and Howard A. Rockman. “β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility..” Proceedings of the National Academy of Sciences of the United States of America 113, no. 50 (December 2016): 14426–31. https://doi.org/10.1073/pnas.1609308113.
Torok, Rachel D., Dennis M. Abraham, Clarice Gareri, Lan Mao, and Howard A. Rockman. “TWIK-Related Acid-Sensitive K+ Channels Affect the Development of Aortic Root Aneurysms in Mice.” In Circulation, Vol. 134. LIPPINCOTT WILLIAMS & WILKINS, 2016.