Dennis M Abraham, MD

Assistant Professor of Medicine
Campus mail 213 Research Drive; CARL Building, Box 102154, Durham, NC 27710
Phone (919) 681-5821
Email address dennis.abraham@duke.edu
In Their Words

Education and Training

  • Resident, Internal Medicine, Icahn School of Medicine at Mount Sinai, 2003 - 2005
  • Intern, Internal Medicine, Icahn School of Medicine at Mount Sinai, 2002 - 2003
  • M.D., Thomas Jefferson University, 2002

Publications

Lee, Chang-Lung, Jessica W. Lee, Andrea R. Daniel, Matt Holbrook, Stephanie Hasapis, Ato O. Wright, Jeremy Brownstein, et al. “Characterization of cardiovascular injury in mice following partial-heart irradiation with clinically relevant dose and fractionation.” Radiother Oncol 157 (April 2021): 155–62. https://doi.org/10.1016/j.radonc.2021.01.023.

PMID
33545252
Full Text

Huffman, Kim M., Brian J. Andonian, Dennis M. Abraham, Akshay Bareja, David E. Lee, Lauren H. Katz, Janet L. Huebner, William E. Kraus, and James P. White. “Exercise protects against cardiac and skeletal muscle dysfunction in a mouse model of inflammatory arthritis.” J Appl Physiol (1985) 130, no. 3 (March 1, 2021): 853–64. https://doi.org/10.1152/japplphysiol.00576.2020.

PMID
33411638
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Sparks, Matthew A., Fitra Rianto, Edward Diaz, Ritika Revoori, Thien Hoang, Lucas Bouknight, Johannes Stegbauer, et al. “Direct Actions of AT1 (Type 1 Angiotensin) Receptors in Cardiomyocytes Do Not Contribute to Cardiac Hypertrophy.” Hypertension 77, no. 2 (February 2021): 393–404. https://doi.org/10.1161/HYPERTENSIONAHA.119.14079.

PMID
33390039
Full Text

Davidson, Michael T., Paul A. Grimsrud, Ling Lai, James A. Draper, Kelsey H. Fisher-Wellman, Tara M. Narowski, Dennis M. Abraham, Timothy R. Koves, Daniel P. Kelly, and Deborah M. Muoio. “Extreme Acetylation of the Cardiac Mitochondrial Proteome Does Not Promote Heart Failure.” Circ Res 127, no. 8 (September 25, 2020): 1094–1108. https://doi.org/10.1161/CIRCRESAHA.120.317293.

PMID
32660330
Full Text

Slosky, Lauren M., Yushi Bai, Krisztian Toth, Caroline Ray, Lauren K. Rochelle, Alexandra Badea, Rahul Chandrasekhar, et al. “β-Arrestin-Biased Allosteric Modulator of NTSR1 Selectively Attenuates Addictive Behaviors.” Cell 181, no. 6 (June 11, 2020): 1364-1379.e14. https://doi.org/10.1016/j.cell.2020.04.053.

PMID
32470395
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Edmonston, Daniel L., Kishan S. Parikh, Sudarshan Rajagopal, Linda K. Shaw, Dennis Abraham, Alexander Grabner, Matthew A. Sparks, and Myles Wolf. “Pulmonary Hypertension Subtypes and Mortality in CKD.” Am J Kidney Dis 75, no. 5 (May 2020): 713–24. https://doi.org/10.1053/j.ajkd.2019.08.027.

PMID
31732231
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Duan, Wei, Jonné Hicks, Michael A. Makara, Olga Ilkayeva, and Dennis M. Abraham. “TASK-1 and TASK-3 channels modulate pressure overload-induced cardiac remodeling and dysfunction.” Am J Physiol Heart Circ Physiol 318, no. 3 (March 1, 2020): H566–80. https://doi.org/10.1152/ajpheart.00739.2018.

PMID
31977249
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Han, Sang-Oh, Alexina C. Haynes, Songtao Li, Dennis M. Abraham, Priya S. Kishnani, Richard Steet, and Dwight D. Koeberl. “Evaluation of antihypertensive drugs in combination with enzyme replacement therapy in mice with Pompe disease.” Mol Genet Metab 129, no. 2 (February 2020): 73–79. https://doi.org/10.1016/j.ymgme.2019.10.005.

PMID
31645300
Full Text

Yu, Samuel Mon-Wei, Pierre-Yves Jean-Charles, Dennis M. Abraham, Suneet Kaur, Clarice Gareri, Lan Mao, Howard A. Rockman, and Sudha K. Shenoy. “The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling.” J Biol Chem 294, no. 7 (February 15, 2019): 2500–2518. https://doi.org/10.1074/jbc.RA118.004926.

PMID
30538132
Full Text

Abraham, Dennis M., Teresa E. Lee, Lewis J. Watson, Lan Mao, Gurangad Chandok, Hong-Gang Wang, Stephan Frangakis, et al. “The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction.” J Clin Invest 128, no. 11 (November 1, 2018): 4843–55. https://doi.org/10.1172/JCI95945.

PMID
30153110
Full Text

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