Dennis M Abraham, MD

Assistant Professor of Medicine
Campus mail 213 Research Drive; CARL Building, Box 102154, Durham, NC 27710
Phone (919) 681-5821
Email address dennis.abraham@duke.edu
In Their Words

Education and Training

  • Resident, Internal Medicine, Icahn School of Medicine at Mount Sinai, 2003 - 2005
  • Intern, Internal Medicine, Icahn School of Medicine at Mount Sinai, 2002 - 2003
  • M.D., Thomas Jefferson University, 2002
Weight
-20

Publications

Edmonston, Daniel L., Kishan S. Parikh, Sudarshan Rajagopal, Linda K. Shaw, Dennis Abraham, Alexander Grabner, Matthew A. Sparks, and Myles Wolf. “Pulmonary Hypertension Subtypes and Mortality in CKD..” Am J Kidney Dis, November 12, 2019. https://doi.org/10.1053/j.ajkd.2019.08.027.

PMID
31732231
Full Text

Han, Sang-Oh, Alexina C. Haynes, Songtao Li, Dennis M. Abraham, Priya S. Kishnani, Richard Steet, and Dwight D. Koeberl. “Evaluation of antihypertensive drugs in combination with enzyme replacement therapy in mice with Pompe disease..” Mol Genet Metab, October 17, 2019. https://doi.org/10.1016/j.ymgme.2019.10.005.

PMID
31645300
Full Text

Yu, Samuel Mon-Wei, Pierre-Yves Jean-Charles, Dennis M. Abraham, Suneet Kaur, Clarice Gareri, Lan Mao, Howard A. Rockman, and Sudha K. Shenoy. “The deubiquitinase ubiquitin-specific protease 20 is a positive modulator of myocardial β1-adrenergic receptor expression and signaling..” J Biol Chem 294, no. 7 (February 15, 2019): 2500–2518. https://doi.org/10.1074/jbc.RA118.004926.

PMID
30538132
Full Text

Abraham, Dennis M., Teresa E. Lee, Lewis J. Watson, Lan Mao, Gurangad Chandok, Hong-Gang Wang, Stephan Frangakis, et al. “The two-pore domain potassium channel TREK-1 mediates cardiac fibrosis and diastolic dysfunction..” J Clin Invest 128, no. 11 (November 1, 2018): 4843–55. https://doi.org/10.1172/JCI95945.

PMID
30153110
Full Text

Hershberger, Kathleen A., Dennis M. Abraham, Juan Liu, Jason W. Locasale, Paul A. Grimsrud, and Matthew D. Hirschey. “Ablation of Sirtuin5 in the postnatal mouse heart results in protein succinylation and normal survival in response to chronic pressure overload..” J Biol Chem 293, no. 27 (July 6, 2018): 10630–45. https://doi.org/10.1074/jbc.RA118.002187.

PMID
29769314
Full Text

Toth, Krisztian, Lauren M. Slosky, Thomas F. Pack, Nikhil M. Urs, Peter Boone, Lan Mao, Dennis Abraham, Marc G. Caron, and Lawrence S. Barak. “Ghrelin receptor antagonism of hyperlocomotion in cocaine-sensitized mice requires βarrestin-2..” Synapse 72, no. 1 (January 2018). https://doi.org/10.1002/syn.22012.

PMID
28941296
Full Text

Hershberger, Kathleen A., Dennis M. Abraham, Angelical S. Martin, Lan Mao, Juan Liu, Hongbo Gu, Jason W. Locasale, and Matthew D. Hirschey. “Sirtuin 5 is required for mouse survival in response to cardiac pressure overload..” J Biol Chem 292, no. 48 (December 1, 2017): 19767–81. https://doi.org/10.1074/jbc.M117.809897.

PMID
28972174
Full Text

Jean-Charles, Pierre-Yves, Samuel Mon-Wei Yu, Dennis Abraham, Reddy Peera Kommaddi, Lan Mao, Ryan T. Strachan, Zhu-Shan Zhang, et al. “Mdm2 regulates cardiac contractility by inhibiting GRK2-mediated desensitization of β-adrenergic receptor signaling..” Jci Insight 2, no. 17 (September 7, 2017). https://doi.org/10.1172/jci.insight.95998.

PMID
28878120
Full Text

Martin, Angelical S., Dennis M. Abraham, Kathleen A. Hershberger, Dhaval P. Bhatt, Lan Mao, Huaxia Cui, Juan Liu, et al. “Nicotinamide mononucleotide requires SIRT3 to improve cardiac function and bioenergetics in a Friedreich's ataxia cardiomyopathy model..” Jci Insight 2, no. 14 (July 20, 2017). https://doi.org/10.1172/jci.insight.93885.

PMID
28724806
Full Text

Abraham, Dennis M., Robert T. Davis, Chad M. Warren, Lan Mao, Beata M. Wolska, R John Solaro, and Howard A. Rockman. “β-Arrestin mediates the Frank-Starling mechanism of cardiac contractility..” Proc Natl Acad Sci U S A 113, no. 50 (December 13, 2016): 14426–31. https://doi.org/10.1073/pnas.1609308113.

PMID
27911784
Full Text

Pages