Dorothy Anna Sipkins, MD, PhD

Associate Professor of Medicine
Associate Research Professor in Pharmacology and Cancer Biology
Member of the Duke Cancer Institute
Affiliate of the Regeneration Next Initiative
Campus mail DUMC 103867, Durham, NC 27710
Email address

Education and Training

  • Hematology-Oncology Fellowship, Hematology Oncology, Dana-Farber Cancer Institute, 2001 - 2005
  • Internship and Residency, Internal Medicine, Massachusetts General Hospital, 1999 - 2001
  • Ph.D., Stanford University, School of Medicine, 1999
  • M.D., Stanford University, School of Medicine, 1999


Yao, Hisayuki, Trevor T. Price, Gaia Cantelli, Brandon Ngo, Matthew J. Warner, Lindsey Olivere, Sarah M. Ridge, et al. “Leukaemia hijacks a neural mechanism to invade the central nervous system.” Nature 560, no. 7716 (August 2018): 55–60.

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Price, Trevor T., Monika L. Burness, Ayelet Sivan, Matthew J. Warner, Renee Cheng, Clara H. Lee, Lindsey Olivere, et al. “Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone.” Sci Transl Med 8, no. 340 (May 25, 2016): 340ra73.

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Price, Trevor T., Clara H. Lee, Qing Cheng, H Kim Lyerly, William E. Fogler, John L. Magnani, and Dorothy A. Sipkins. “Abstract 3212: Metastatic breast cancer cell communication within a pro-dormancy bone marrow niche.” In Tumor Biology. American Association for Cancer Research, 2015.

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Price, Trevor, Monika Burness, Ayelet Sivan, Renee Cheng, John L. Magnani, and Dorothy A. Sipkins. “Abstract 4831: Breast cancer cells metastasize to bone through E-selectin+ vascular gateways.” In Tumor Biology. American Association for Cancer Research, 2014.

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Burger, J. A., and D. A. Sipkins. “The bone marrow microenvironment and its impact in acute and chronic B cell malignancies.” In Bone Marrow Lymphoid Infiltrates: Diagnosis and Clinical Impact, 35–45, 2013.

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Fox, Matthew F., Andrea Pontier, Sandeep Gurbuxani, and Dorothy A. Sipkins. “Stem cell factor expression in B cell malignancies is influenced by the niche.” Leuk Lymphoma 54, no. 10 (October 2013): 2274–80.

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Boyerinas, Benjamin, Maya Zafrir, Ali E. Yesilkanal, Trevor T. Price, Elizabeth M. Hyjek, and Dorothy A. Sipkins. “Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy.” Blood 121, no. 24 (June 13, 2013): 4821–31.

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Horton, Brendan, Maya Zafrir, Pauline Wales, Andrea Pontier, Ayalew Tefferi, and Dorothy A. Sipkins. “Polycythemia Vera and Chronic Idiopathic Myelofibrosis CD34+ Cells Preferentially Traffic to Splenic Niches.” In Blood, 120:1750–1750. American Society of Hematology, 2012.

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Agarwal, Rajiv, Frederick L. Locke, Rangesh Kunnavakkam, Koen van Besien, Richard A. Larson, Olatoyosi Odenike, Lucy Godley, et al. “A Phase II Prospective Feasibility Study of Clofarabine Cytoreduction Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) for Patients with Relapsed or Refractory Acute Leukemias and Advanced Myelodysplastic Syndromes.” In Blood, 118:231–32. AMER SOC HEMATOLOGY, 2011.