Dorothy Anna Sipkins, MD, PhD

Associate Professor of Medicine
Associate Research Professor in Pharmacology and Cancer Biology
Member of the Duke Cancer Institute
Affiliate of the Regeneration Next Initiative
Campus mail DUMC 103867, Durham, NC 27710
Email address dorothy.sipkins@duke.edu

Education and Training

  • Hematology-Oncology Fellowship, Hematology Oncology, Dana Farber Cancer Institute, 2001 - 2005
  • Internship and Residency, Internal Medicine, Massachusetts General Hospital, 1999 - 2001
  • Ph.D., Stanford University School of Medicine, 1999
  • M.D., Stanford University School of Medicine, 1999

Publications

Yao, H, Price, TT, Cantelli, G, Ngo, B, Warner, MJ, Olivere, L, Ridge, SM, Jablonski, EM, Therrien, J, Tannheimer, S, McCall, CM, Chenn, A, and Sipkins, DA. "Leukaemia hijacks a neural mechanism to invade the central nervous system." Nature 560, no. 7716 (August 2018): 55-60.

PMID
30022166
Full Text

Price, TT, Burness, ML, Sivan, A, Warner, MJ, Cheng, R, Lee, CH, Olivere, L, Comatas, K, Magnani, J, Kim Lyerly, H, Cheng, Q, McCall, CM, and Sipkins, DA. "Dormant breast cancer micrometastases reside in specific bone marrow niches that regulate their transit to and from bone." Science Translational Medicine 8, no. 340 (May 2016): 340ra73-null.

PMID
27225183
Full Text

Price, TT, Lee, CH, Cheng, Q, Lyerly, HK, Fogler, WE, Magnani, JL, and Sipkins, DA. "Abstract 3212: Metastatic breast cancer cell communication within a pro-dormancy bone marrow niche." August 1, 2015.

Full Text

Price, T, Burness, M, Sivan, A, Cheng, R, Magnani, JL, and Sipkins, DA. "Abstract 4831: Breast cancer cells metastasize to bone through E-selectin+ vascular gateways." October 1, 2014.

Full Text

Price, T, and Sipkins, DA. "Rewiring the niche: sympathetic neuropathy drives malignant niche transformation." Cell stem cell 15, no. 3 (September 2014): 261-262.

PMID
25192459
Full Text

Burger, JA, and Sipkins, DA. "The bone marrow microenvironment and its impact in acute and chronic B cell malignancies." In Bone Marrow Lymphoid Infiltrates: Diagnosis and Clinical Impact, 35-45. November 1, 2013.

Full Text

Fox, MF, Pontier, A, Gurbuxani, S, and Sipkins, DA. "Stem cell factor expression in B cell malignancies is influenced by the niche." Leukemia & lymphoma 54, no. 10 (October 2013): 2274-2280.

PMID
23418895
Full Text

Boyerinas, B, Zafrir, M, Yesilkanal, AE, Price, TT, Hyjek, EM, and Sipkins, DA. "Adhesion to osteopontin in the bone marrow niche regulates lymphoblastic leukemia cell dormancy." Blood 121, no. 24 (June 2013): 4821-4831.

PMID
23589674
Full Text

Horton, B, Zafrir, M, Wales, P, Pontier, A, Tefferi, A, and Sipkins, DA. "Polycythemia Vera and Chronic Idiopathic Myelofibrosis CD34+Cells Preferentially Traffic to Splenic Niches." November 16, 2012.

Scholars@Duke

Agarwal, R, Locke, FL, Kunnavakkam, R, van Besien, K, Larson, RA, Odenike, O, Godley, L, Liu, H, Le Beau, MM, Gurbuxani, S, Thirman, MJ, Sipkins, DA, White, C, Artz, A, and Stock, W. "A Phase II Prospective Feasibility Study of Clofarabine Cytoreduction Prior to Allogeneic Hematopoietic Cell Transplantation (HCT) for Patients with Relapsed or Refractory Acute Leukemias and Advanced Myelodysplastic Syndromes." November 18, 2011.

Scholars@Duke

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