Hans-Ewald Hohmeier, MD, PhD

Associate Professor in Medicine
Member of Sarah W. Stedman Nutrition and Metabolism Center
Affiliate of the Regeneration Next Initiative
Campus mail 300 N Duke Street, Durham, NC 27701
Phone (919) 479-2342
Email address hans.hohmeier@duke.edu

Education and Training

  • Postdoctoral Fellow, Biochemistry, UT Southwestern Medical School, 1995 - 1997
  • Postdoctoral Fellow, Immunology, UT Southwestern Medical School, 1991 - 1995
  • Ph.D., Georg August Universitat Gottingen (Germany), 1992
  • M.D., University of Hannover (Germany), 1986

Publications

Hayes, Heather L., Brett S. Peterson, Jonathan M. Haldeman, Christopher B. Newgard, Hans E. Hohmeier, and Samuel B. Stephens. “Delayed apoptosis allows islet β-cells to implement an autophagic mechanism to promote cell survival..” Plos One 12, no. 2 (2017). https://doi.org/10.1371/journal.pone.0172567.

PMID
28212395
Full Text

Hayes, Heather L., Lu Zhang, Thomas C. Becker, Jonathan M. Haldeman, Samuel B. Stephens, Michelle Arlotto, Larry G. Moss, Christopher B. Newgard, and Hans E. Hohmeier. “A Pdx-1-Regulated Soluble Factor Activates Rat and Human Islet Cell Proliferation..” Mol Cell Biol 36, no. 23 (December 1, 2016): 2918–30. https://doi.org/10.1128/MCB.00103-16.

PMID
27620967
Full Text

Shang, Jin, Jing Li, Mark P. Keller, Hans E. Hohmeier, Yong Wang, Yue Feng, Heather H. Zhou, et al. “Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells..” Mol Endocrinol 29, no. 9 (September 2015): 1243–53. https://doi.org/10.1210/me.2014-1335.

PMID
26218441
Full Text

Lorenzo, Damaris N., Jane A. Healy, Janell Hostettler, Jonathan Davis, Jiayu Yang, Chao Wang, Hans Ewald Hohmeier, Mingjie Zhang, and Vann Bennett. “Ankyrin-B metabolic syndrome combines age-dependent adiposity with pancreatic β cell insufficiency..” J Clin Invest 125, no. 8 (August 3, 2015): 3087–3102. https://doi.org/10.1172/JCI81317.

PMID
26168218
Full Text

Tessem, Jeffery S., Larry G. Moss, Lily C. Chao, Michelle Arlotto, Danhong Lu, Mette V. Jensen, Samuel B. Stephens, Peter Tontonoz, Hans E. Hohmeier, and Christopher B. Newgard. “Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors..” Proc Natl Acad Sci U S A 111, no. 14 (April 8, 2014): 5242–47. https://doi.org/10.1073/pnas.1320953111.

PMID
24706823
Full Text

Hayes, Heather L., Larry G. Moss, Jonathan C. Schisler, Jonathan M. Haldeman, Zhushan Zhang, Paul B. Rosenberg, Christopher B. Newgard, and Hans E. Hohmeier. “Pdx-1 activates islet α- and β-cell proliferation via a mechanism regulated by transient receptor potential cation channels 3 and 6 and extracellular signal-regulated kinases 1 and 2..” Mol Cell Biol 33, no. 20 (October 2013): 4017–29. https://doi.org/10.1128/MCB.00469-13.

PMID
23938296
Full Text

Jensen, Mette V., Jonathan M. Haldeman, Hengtao Zhang, Danhong Lu, Mark O. Huising, Wylie W. Vale, Hans E. Hohmeier, Paul Rosenberg, and Christopher B. Newgard. “Control of voltage-gated potassium channel Kv2.2 expression by pyruvate-isocitrate cycling regulates glucose-stimulated insulin secretion..” J Biol Chem 288, no. 32 (August 9, 2013): 23128–40. https://doi.org/10.1074/jbc.M113.491654.

PMID
23788641
Full Text

Li, Xiaoyan Nina, James Herrington, Aleksandr Petrov, Lan Ge, George Eiermann, Yusheng Xiong, Mette V. Jensen, et al. “The role of voltage-gated potassium channels Kv2.1 and Kv2.2 in the regulation of insulin and somatostatin release from pancreatic islets..” J Pharmacol Exp Ther 344, no. 2 (February 2013): 407–16. https://doi.org/10.1124/jpet.112.199083.

PMID
23161216
Full Text

Stephens, Samuel B., Jonathan C. Schisler, Hans E. Hohmeier, Jie An, Albert Y. Sun, Geoffrey S. Pitt, and Christopher B. Newgard. “A VGF-derived peptide attenuates development of type 2 diabetes via enhancement of islet β-cell survival and function..” Cell Metab 16, no. 1 (July 3, 2012): 33–43. https://doi.org/10.1016/j.cmet.2012.05.011.

PMID
22768837
Full Text

Pages