Harry Paul Erba, MD, PhD

Instructor in the Department of Medicine
Member of the Duke Cancer Institute
Campus mail 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
Phone (919) 668-1000
Email address harry.erba@duke.edu

I am a clinical investigator in the Division of Hematologic Malignancies and Cellular Therapy in the Department of Medicine.  I serve as Director of the Leukemia Program and Director of Phase I Development in Hematologic Malignancies.  I am also the Chair of the SWOG Leukemia Committee.  I am interested in the clinical development of novel therapies for acute myeloid leukemia, myelodysplastic syndromes, myeloproliferative neoplasms (such as chronic myeloid leukemia, polycythemia vera, essential thrombocythemia and myelofibrosis), and acute lymphoblastic leukemia.  Specifically, I have been the Principal Investigator for small molecular inhibitors, antibody-drug conjugates and cytotoxic chemotherapy.  

Education and Training

  • Research Fellowship in Medicine, Medicine, Harvard Medical School, 1991 - 1993
  • Research/Clinical Fellowship in Medicine, Medicine, Brigham and Women's Hospital, 1991 - 1992
  • Clinical Fellow in Medicine, Medicine, Harvard Medical School, 1988 - 1991
  • Residency Physician, Medicine, Brigham and Women's Hospital, 1988 - 1990
  • Ph.D., Stanford University, 1988
  • M.D., Stanford University, School of Medicine, 1988

Grants

Publications

DiNardo, Courtney D., Eytan M. Stein, Arnaud Pigneux, Jessica K. Altman, Robert Collins, Harry P. Erba, Justin M. Watts, et al. “Outcomes of patients with IDH1-mutant relapsed or refractory acute myeloid leukemia receiving ivosidenib who proceeded to hematopoietic stem cell transplant.” Leukemia, March 26, 2021. https://doi.org/10.1038/s41375-021-01229-x.

PMID
33772143
Full Text

Othus, Megan, Guillermo Garcia-Manero, John Godwin, James Weick, Derek Stirewalt, Frederick Appelbaum, Harry Erba, and Elihu Estey. “Associations between complete remission and 2- to 3-year survival following 7 + 3 induction for acute myeloid leukemia.” Leuk Lymphoma, March 10, 2021, 1–6. https://doi.org/10.1080/10428194.2021.1885663.

PMID
33719833
Full Text

Uy, Geoffrey L., Ibrahim Aldoss, Matthew C. Foster, Peter H. Sayre, Matthew J. Wieduwilt, Anjali S. Advani, John E. Godwin, et al. “Flotetuzumab as salvage immunotherapy for refractory acute myeloid leukemia.” Blood 137, no. 6 (February 11, 2021): 751–62. https://doi.org/10.1182/blood.2020007732.

PMID
32929488
Full Text

Moseley, Anna, Megan Othus, Guillermo Garcia-Manero, Frederick R. Appelbaum, Harry P. Erba, and Roland B. Walter. “Predicting severe toxicities with intensive induction chemotherapy for adult acute myeloid leukemia: analysis of SWOG Cancer Research Network trials S0106 and S1203.” Leuk Lymphoma, February 9, 2021, 1–7. https://doi.org/10.1080/10428194.2021.1881512.

PMID
33560164
Full Text

Advani, Anjali S., Eric Larsen, Kristina Laumann, Selina M. Luger, Michaela Liedtke, Meenakshi Devidas, Zhiguo Chen, et al. “Comparison of CALGB 10403 (Alliance) and COG AALL0232 toxicity results in young adults with acute lymphoblastic leukemia.” Blood Adv 5, no. 2 (January 26, 2021): 504–12. https://doi.org/10.1182/bloodadvances.2020002439.

PMID
33496745
Full Text

Patel, Jay L., Mehrdad Abedi, Christopher R. Cogle, Harry P. Erba, Kathryn Foucar, Guillermo Garcia-Manero, David L. Grinblatt, et al. “Real-world diagnostic testing patterns for assessment of ring sideroblasts and SF3B1 mutations in patients with newly diagnosed lower-risk myelodysplastic syndromes.” Int J Lab Hematol, November 21, 2020. https://doi.org/10.1111/ijlh.13400.

PMID
33220019
Full Text

Arber, Daniel A., and Harry P. Erba. “Diagnosis and Treatment of Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Changes (AML-MRC).” Am J Clin Pathol 154, no. 6 (November 4, 2020): 731–41. https://doi.org/10.1093/ajcp/aqaa107.

PMID
32864703
Full Text

Shah, Gaurav, Fady M. Mikhail, Kimo Bachiasvili, Pankit Vachhani, Harry P. Erba, and Nikolaos Papadantonakis. “Outcomes of high-risk acute promyelocytic leukemia patients treated with arsenic trioxide (ATO)/all trans retinoic acid (ATRA) based induction and consolidation without maintenance phase: A case Series.” Hematol Oncol Stem Cell Ther 13, no. 3 (September 2020): 143–46. https://doi.org/10.1016/j.hemonc.2019.08.006.

PMID
31629725
Full Text

Sekeres, Mikkael A., Gordon Guyatt, Gregory Abel, Shabbir Alibhai, Jessica K. Altman, Rena Buckstein, Hannah Choe, et al. “American Society of Hematology 2020 guidelines for treating newly diagnosed acute myeloid leukemia in older adults.” Blood Adv 4, no. 15 (August 11, 2020): 3528–49. https://doi.org/10.1182/bloodadvances.2020001920.

PMID
32761235
Full Text

Zeidan, Amer M., Prajwal C. Boddu, Mrinal M. Patnaik, Jan Philipp Bewersdorf, Maximilian Stahl, Raajit K. Rampal, Rory Shallis, et al. “Special considerations in the management of adult patients with acute leukaemias and myeloid neoplasms in the COVID-19 era: recommendations from a panel of international experts.” Lancet Haematol 7, no. 8 (August 2020): e601–12. https://doi.org/10.1016/S2352-3026(20)30205-2.

PMID
32563283
Full Text

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