Hope Elizabeth Uronis, MD

Associate Professor of Medicine
Member of the Duke Cancer Institute
Campus mail 435 Seeley G. Mudd Building, Box 2823, Durham, NC 27710
Phone (919) 681-6006
In Their Words

Education and Training

  • Fellow in Hematology-Oncology, Medicine, Duke University, 2005 - 2007
  • Chief Medical Resident -Duke Hospital, Medicine, Duke University, 2004 - 2005
  • Fellow in Hematology-Oncology, Medicine, Duke University, 2003 - 2004
  • Medical Resident, Medicine, Duke University, 2000 - 2003
  • M.D., State University of New York - Buffalo, 2000

Publications

Creasy, John M., Kyle J. Napier, Sarah A. Reed, Sabino Zani, Terence Z. Wong, Charles Y. Kim, Benjamin Wildman-Tobriner, et al. “Implementation of a Hepatic Artery Infusion Program: Initial Patient Selection and Perioperative Outcomes of Concurrent Hepatic Artery Infusion and Systemic Chemotherapy for Colorectal Liver Metastases.” Ann Surg Oncol 27, no. 13 (December 2020): 5086–95. https://doi.org/10.1245/s10434-020-08972-y.

PMID
32779054
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Sohal, Davendra P. S., Erin B. Kennedy, Pelin Cinar, Thierry Conroy, Mehmet S. Copur, Christopher H. Crane, Ignacio Garrido-Laguna, et al. “Metastatic Pancreatic Cancer: ASCO Guideline Update.” J Clin Oncol, August 5, 2020, JCO2001364. https://doi.org/10.1200/JCO.20.01364.

PMID
32755482
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Catenacci, Daniel V. T., Yoon-Koo Kang, Haeseong Park, Hope E. Uronis, Keun-Wook Lee, Matthew C. H. Ng, Peter C. Enzinger, et al. “Margetuximab plus pembrolizumab in patients with previously treated, HER2-positive gastro-oesophageal adenocarcinoma (CP-MGAH22-05): a single-arm, phase 1b-2 trial.” Lancet Oncol 21, no. 8 (August 2020): 1066–76. https://doi.org/10.1016/S1470-2045(20)30326-0.

PMID
32653053
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Cinar, Pelin, Timothy Kubal, Alison Freifeld, Asmita Mishra, Lawrence Shulman, James Bachman, Rafael Fonseca, et al. “Safety at the Time of the COVID-19 Pandemic: How to Keep our Oncology Patients and Healthcare Workers Safe.” J Natl Compr Canc Netw, April 15, 2020, 1–6. https://doi.org/10.6004/jnccn.2020.7572.

PMID
32294617
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Eng, Cathy, Marwan Fakih, Manik Amin, Van Morris, Howard S. Hochster, Patrick M. Boland, and Hope Uronis. “A phase II study of axalimogene filolisbac for patients with previously treated, unresectable, persistent/recurrent loco-regional or metastatic anal cancer.” Oncotarget 11, no. 15 (April 14, 2020): 1334–43. https://doi.org/10.18632/oncotarget.27536.

PMID
32341753
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Strickler, John H., Christel N. Rushing, Donna Niedzwiecki, Abigail McLeod, Ivy Altomare, Hope E. Uronis, S David Hsu, et al. “A phase Ib study of capecitabine and ziv-aflibercept followed by a phase II single-arm expansion cohort in chemotherapy refractory metastatic colorectal cancer.” Bmc Cancer 19, no. 1 (November 1, 2019): 1032. https://doi.org/10.1186/s12885-019-6234-8.

PMID
31675952
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Clarke, Jeffrey Melson, Gerard C. Blobe, John H. Strickler, Hope Elizabeth Uronis, S Yousuf Zafar, Michael Morse, Evan Dropkin, et al. “A phase Ib study of the combination regorafenib with PF-03446962 in patients with refractory metastatic colorectal cancer (REGAL-1 trial).” Cancer Chemother Pharmacol 84, no. 4 (October 2019): 909–17. https://doi.org/10.1007/s00280-019-03916-0.

PMID
31444620
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Mettu, Niharika B., Donna Niedzwiecki, Christel Rushing, Andrew B. Nixon, Jingquan Jia, Sherri Haley, Wanda Honeycutt, Herbert Hurwitz, Johanna C. Bendell, and Hope Uronis. “A phase I study of gemcitabine + dasatinib (gd) or gemcitabine + dasatinib + cetuximab (GDC) in refractory solid tumors.” In Cancer Chemother Pharmacol, 83:1025–35, 2019. https://doi.org/10.1007/s00280-019-03805-6.

PMID
30895346
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Catenacci, Daniel V. T., Kian Huat Lim, Hope Elizabeth Uronis, Yoon-Koo Kang, Matthew C. H. Ng, Philip Jordan Gold, Peter C. Enzinger, et al. “Antitumor activity of margetuximab (M) plus pembrolizumab (P) in patients (pts) with advanced HER2+ (IHC3+) gastric carcinoma (GC).” In Journal of Clinical Oncology, 37:65–65. American Society of Clinical Oncology (ASCO), 2019. https://doi.org/10.1200/jco.2019.37.4_suppl.65.

Full Text

Catenacci, D. V. T., H. Park, H. E. Uronis, Y. -. K. Kang, M. Ng, P. Gold, J. Lacy, et al. “Biomarker-guided enrichment of the antitumor activity of margetuximab (M) plus pembrolizumab (P) in patients with advanced HER2+ gastric adenocarcinoma (GEA).” In Ann Oncol, 29 Suppl 8:viii223, 2018. https://doi.org/10.1093/annonc/mdy282.046.

PMID
32136480
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