James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Duan, Bensong, Jiangfeng Hu, Hongliang Liu, Yanru Wang, Hongyu Li, Shun Liu, Jichun Xie, et al. “Genetic variants in the platelet-derived growth factor subunit B gene associated with pancreatic cancer risk..” Int J Cancer 142, no. 7 (April 1, 2018): 1322–31. https://doi.org/10.1002/ijc.31171.

PMID
29168174
Full Text

Berlin, Jordan D., Yang Feng, Paul Catalano, James L. Abbruzzese, Philip A. Philip, Robert R. McWilliams, Andrew M. Lowy, Al B. Benson, and A William Blackstock. “An Intergroup Randomized Phase II Study of Bevacizumab or Cetuximab in Combination with Gemcitabine and in Combination with Chemoradiation in Patients with Resected Pancreatic Carcinoma: A Trial of the ECOG-ACRIN Cancer Research Group (E2204)..” Oncology 94, no. 1 (2018): 39–46. https://doi.org/10.1159/000480295.

PMID
29040974
Full Text

Andersen, Dana K., Murray Korc, Gloria M. Petersen, Guido Eibl, Donghui Li, Michael R. Rickels, Suresh T. Chari, and James L. Abbruzzese. “Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer..” Diabetes 66, no. 5 (May 2017): 1103–10. https://doi.org/10.2337/db16-1477.

PMID
28507210
Full Text

Capello, Michela, Leonidas E. Bantis, Ghislaine Scelo, Yang Zhao, Peng Li, Dilsher S. Dhillon, Nikul J. Patel, et al. “Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer..” J Natl Cancer Inst 109, no. 4 (April 1, 2017). https://doi.org/10.1093/jnci/djw266.

PMID
28376157
Full Text

Capello, Michela, Leonidas E. Bantis, Ghislaine Scelo, Yang Zhao, Peng Li, Dilsher S. Dhillon, Nikul J. Patel, et al. “Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer..” J Natl Cancer Inst 109, no. 4 (April 2017). https://doi.org/10.1093/jnci/djw266.

PMID
27986802
Full Text

Cloyd, Jordan M., Matthew H. G. Katz, Laura Prakash, Gauri R. Varadhachary, Robert A. Wolff, Rachna T. Shroff, Milind Javle, et al. “Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience..” J Gastrointest Surg 21, no. 1 (January 2017): 164–74. https://doi.org/10.1007/s11605-016-3265-1.

PMID
27778257
Full Text

Ye, Min, Weiqin Lu, Xiaojie Wang, Cong Wang, James L. Abbruzzese, Guang Liang, Xiaokun Li, and Yongde Luo. “FGF21-FGFR1 Coordinates Phospholipid Homeostasis, Lipid Droplet Function, and ER Stress in Obesity..” Endocrinology 157, no. 12 (December 2016): 4754–69. https://doi.org/10.1210/en.2016-1710.

PMID
27690692
Full Text

Palta, M., B. Czito, J. Abbruzzese, H. Uronis, E. A. Duffy, D. T. Blazer, and C. G. Willett. “Interim Acute Toxicity Analysis and Surgical Outcomes of Neoadjuvant Gemcitabine/nab-Paclitaxel and Hypofractionated Image Guided Intensity Modulated Radiation Therapy in Resectable and Borderline Resectable Pancreatic Cancer (ANCHOR) Study..” Int J Radiat Oncol Biol Phys 96, no. 2S (October 1, 2016): S204–5. https://doi.org/10.1016/j.ijrobp.2016.06.509.

PMID
27675789
Full Text

Pages