James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Palta, M, Czito, B, Abbruzzese, J, Uronis, H, Duffy, EA, Blazer, DT, and Willett, CG. "Interim Acute Toxicity Analysis and Surgical Outcomes of Neoadjuvant Gemcitabine/nab-Paclitaxel and Hypofractionated Image Guided Intensity Modulated Radiation Therapy in Resectable and Borderline Resectable Pancreatic Cancer (ANCHOR) Study." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): S204-S205.

PMID
27675789
Full Text

Zhang, T, Boominathan, R, Foulk, B, Rao, C, Kemeny, G, Strickler, JH, Abbruzzese, JL, Harrison, MR, Hsu, DS, Healy, P, Li, J, Pi, C, Prendergast, KM, Hobbs, C, Gemberling, S, George, DJ, Hurwitz, HI, Connelly, M, Garcia-Blanco, MA, and Armstrong, AJ. "Development of a Novel c-MET-Based CTC Detection Platform." Molecular cancer research : MCR 14, no. 6 (June 2016): 539-547.

PMID
26951228
Full Text

Overman, MJ, Morris, V, Kee, B, Fogelman, D, Xiao, L, Eng, C, Dasari, A, Shroff, R, Mazard, T, Shaw, K, Vilar, E, Raghav, K, Shureiqi, I, Liang, L, Mills, GB, Wolff, RA, Hamilton, S, Meric-Bernstam, F, Abbruzzese, J, Morris, J, Maru, D, and Kopetz, S. "Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials." Annals of oncology : official journal of the European Society for Medical Oncology 27, no. 6 (June 2016): 1068-1074.

PMID
27045102
Full Text

Parsons, HA, Baracos, VE, Hong, DS, Abbruzzese, J, Bruera, E, and Kurzrock, R. "The effects of curcumin (diferuloylmethane) on body composition of patients with advanced pancreatic cancer." Oncotarget 7, no. 15 (April 2016): 20293-20304.

PMID
26934122
Full Text

Li, D, Moughan, J, Crane, C, Hoffman, JP, Regine, WF, Abrams, RA, Safran, H, Liu, C, Chang, P, Freedman, GM, Winter, KA, Guha, C, and Abbruzzese, JL. "RECQ1 A159C Polymorphism Is Associated With Overall Survival of Patients With Resected Pancreatic Cancer: A Replication Study in NRG Oncology Radiation Therapy Oncology Group 9704." International journal of radiation oncology, biology, physics 94, no. 3 (March 2016): 554-560.

PMID
26725729
Full Text

Mettu, NB, and Abbruzzese, JL. "Clinical Insights Into the Biology and Treatment of Pancreatic Cancer." Journal of oncology practice 12, no. 1 (January 2016): 17-23. (Review)

PMID
26759461
Full Text

Raghav, KPS, Mahajan, S, Yao, JC, Hobbs, BP, Berry, DA, Pentz, RD, Tam, A, Hong, WK, Ellis, LM, Abbruzzese, J, and Overman, MJ. "From Protocols to Publications: A Study in Selective Reporting of Outcomes in Randomized Trials in Oncology." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 33, no. 31 (November 2015): 3583-3590. (Review)

PMID
26304898
Full Text

Lu, W, Yang, Y, Luo, Y, Liu, Y, Wang, X, Liu, M, Wolff, RA, Abbruzzese, JL, and Logsdon, CD. "FGF21 Delays Pancreatic Cancer Formation and Prevents Liver Metastasis in Oncogenic Kras Expressing Mice Fed on High-Fat Diet." PANCREAS 44, no. 8 (November 2015): 1393-1393.

Scholars@Duke

Li, D, Pise, MN, Overman, MJ, Liu, C, Tang, H, Vadhan-Raj, S, and Abbruzzese, JL. "ABO non-O type as a risk factor for thrombosis in patients with pancreatic cancer." Cancer medicine 4, no. 11 (November 2015): 1651-1658.

PMID
26275671
Full Text

Fogelman, D, Javle, M, and Abbruzzese, J. "Molecular Therapeutics: Pancreatic Cancer." In Targeted Therapy in Translational Cancer Research, 255-262. October 30, 2015.

Full Text

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