James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Andersen, DK, Korc, M, Petersen, GM, Eibl, G, Li, D, Rickels, MR, Chari, ST, and Abbruzzese, JL. "Diabetes, Pancreatogenic Diabetes, and Pancreatic Cancer." Diabetes 66, no. 5 (May 2017): 1103-1110.

PMID
28507210
Full Text

Capello, M, Bantis, LE, Scelo, G, Zhao, Y, Li, P, Dhillon, DS, Patel, NJ, Kundnani, DL, Wang, H, Abbruzzese, JL, Maitra, A, Tempero, MA, Brand, R, Brennan, L, Feng, E, Taguchi, I, Janout, V, Firpo, MA, Mulvihill, SJ, Katz, MH, and Hanash, SM. "Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer." Journal of the National Cancer Institute 109, no. 4 (April 2017).

PMID
27986802
Scholars@Duke

Capello, M, Bantis, LE, Scelo, G, Zhao, Y, Li, P, Dhillon, DS, Patel, NJ, Kundnani, DL, Wang, H, Abbruzzese, JL, Maitra, A, Tempero, MA, Brand, R, Firpo, MA, Mulvihill, SJ, Katz, MH, Brennan, P, Feng, Z, Taguchi, A, and Hanash, SM. "Sequential Validation of Blood-Based Protein Biomarker Candidates for Early-Stage Pancreatic Cancer." Journal of the National Cancer Institute 109, no. 4 (April 2017).

PMID
28376157
Full Text

Cloyd, JM, Katz, MHG, Prakash, L, Varadhachary, GR, Wolff, RA, Shroff, RT, Javle, M, Fogelman, D, Overman, M, Crane, CH, Koay, EJ, Das, P, Krishnan, S, Minsky, BD, Lee, JH, Bhutani, MS, Weston, B, Ross, W, Bhosale, P, Tamm, EP, Wang, H, Maitra, A, Kim, MP, Aloia, TA, Vauthey, J-N, Fleming, JB, Abbruzzese, JL, Pisters, PWT, Evans, DB, and Lee, JE. "Preoperative Therapy and Pancreatoduodenectomy for Pancreatic Ductal Adenocarcinoma: a 25-Year Single-Institution Experience." Journal of Gastrointestinal Surgery : Official Journal of the Society for Surgery of the Alimentary Tract 21, no. 1 (January 2017): 164-174.

PMID
27778257
Full Text

Ye, M, Lu, W, Wang, X, Wang, C, Abbruzzese, JL, Liang, G, Li, X, and Luo, Y. "FGF21-FGFR1 Coordinates Phospholipid Homeostasis, Lipid Droplet Function, and ER Stress in Obesity." Endocrinology 157, no. 12 (December 2016): 4754-4769.

PMID
27690692
Full Text

Palta, M, Czito, B, Abbruzzese, J, Uronis, H, Duffy, EA, Blazer, DT, and Willett, CG. "Interim Acute Toxicity Analysis and Surgical Outcomes of Neoadjuvant Gemcitabine/nab-Paclitaxel and Hypofractionated Image Guided Intensity Modulated Radiation Therapy in Resectable and Borderline Resectable Pancreatic Cancer (ANCHOR) Study." October 1, 2016.

Full Text

Palta, M, Czito, B, Abbruzzese, J, Uronis, H, Duffy, EA, Blazer, DT, and Willett, CG. "Interim Acute Toxicity Analysis and Surgical Outcomes of Neoadjuvant Gemcitabine/nab-Paclitaxel and Hypofractionated Image Guided Intensity Modulated Radiation Therapy in Resectable and Borderline Resectable Pancreatic Cancer (ANCHOR) Study." October 1, 2016.

Scholars@Duke

Palta, M, Czito, B, Abbruzzese, J, Uronis, H, Duffy, EA, Blazer, DT, and Willett, CG. "Interim Acute Toxicity Analysis and Surgical Outcomes of Neoadjuvant Gemcitabine/nab-Paclitaxel and Hypofractionated Image Guided Intensity Modulated Radiation Therapy in Resectable and Borderline Resectable Pancreatic Cancer (ANCHOR) Study." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): S204-S205.

PMID
27675789
Full Text

Zhang, T, Boominathan, R, Foulk, B, Rao, C, Kemeny, G, Strickler, JH, Abbruzzese, JL, Harrison, MR, Hsu, DS, Healy, P, Li, J, Pi, C, Prendergast, KM, Hobbs, C, Gemberling, S, George, DJ, Hurwitz, HI, Connelly, M, Garcia-Blanco, MA, and Armstrong, AJ. "Development of a Novel c-MET-Based CTC Detection Platform." Mol Cancer Res 14, no. 6 (June 2016): 539-547.

PMID
26951228
Full Text

Overman, MJ, Morris, V, Kee, B, Fogelman, D, Xiao, L, Eng, C, Dasari, A, Shroff, R, Mazard, T, Shaw, K, Vilar, E, Raghav, K, Shureiqi, I, Liang, L, Mills, GB, Wolff, RA, Hamilton, S, Meric-Bernstam, F, Abbruzzese, J, Morris, J, Maru, D, and Kopetz, S. "Utility of a molecular prescreening program in advanced colorectal cancer for enrollment on biomarker-selected clinical trials." Annals of Oncology : Official Journal of the European Society for Medical Oncology 27, no. 6 (June 2016): 1068-1074.

PMID
27045102
Full Text

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