James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Abbruzzese, JL, Weeks, A, Raber, MN, Gravel, D, DuBrow, RA, Levin, B, Grem, J, and Chun, HG. "Phase I trial of semustine plus weekly fluorouracil and high-dose leucovorin calcium in patients with advanced colorectal cancer." JNCI Journal of the National Cancer Institute 81, no. 23 (December 1989): 1840-1842.

PMID
2585532
Full Text

Abbruzzese, JL, Schmidt, S, Raber, MN, Levy, JK, Castellanos, AM, Legha, SS, and Krakoff, IH. "Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity." Investigational new drugs 7, no. 2-3 (July 1989): 195-201.

PMID
2793372
Full Text

Abbruzzese, JL, Levin, B, Ajani, JA, Faintuch, JS, Saks, S, Patt, YZ, Edwards, C, Ende, K, and Gutterman, JU. "Phase I trial of recombinant human gamma-interferon and recombinant human tumor necrosis factor in patients with advanced gastrointestinal cancer." Cancer research 49, no. 14 (July 1989): 4057-4061.

PMID
2500234
Scholars@Duke

Ajani, JA, Rios, AA, Ende, K, Abbruzzese, JL, Edwards, C, Faintuch, JS, Saks, S, Gutterman, JU, and Levin, B. "Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma." Journal of biological response modifiers 8, no. 2 (April 1989): 140-146.

PMID
2499663
Scholars@Duke

Abbruzzese, JL, and Levin, B. "Treatment of advanced colorectal cancer." Hematology/Oncology Clinics of North America 3, no. 1 (March 1989): 135-153. (Review)

PMID
2465291
Full Text

Rich, TA, Hughes, LL, Jessup, JM, Ota, DM, Ames, FC, Hohn, DC, Martin, RG, Ajani, JA, and Abbruzzese, JL. "Conservative management of anal and low rectal cancers with combined modality therapy." Cancer Bulletin 41, no. 2 (January 1, 1989): 71-74.

Scholars@Duke

Ajani, JA, Goudeau, P, Levin, B, Faintuch, JS, Abbruzzese, JL, Boman, BM, and Kanojia, MD. "Phase II study of adriamycin with sequential methotrexate and 5-fluorouracil (AMF) in gastric carcinoma." Cancer chemotherapy and pharmacology 24, no. 1 (January 1989): 41-44.

PMID
2720890
Full Text

Ajani, JA, Abbruzzese, JL, Goudeau, P, Faintuch, JS, Yeomans, AC, Boman, BM, Nicaise, C, and Levin, B. "Ifosfamide and mesna: marginally active in patients with advanced carcinoma of the pancreas." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 6, no. 11 (November 1988): 1703-1707.

PMID
3141592
Full Text

Ajani, JA, Abbruzzese, JL, Faintuch, JS, Blackburn, R, Levin, B, and Boman, BM. "Phase II study of fludarabine phosphate in patients with advanced colorectal carcinoma." Investigational new drugs 6, no. 1 (April 1988): 47-50.

PMID
2457566
Full Text

Abbruzzese, JL. "Recent approaches to the systemic therapy of advanced colorectal carcinoma." Cancer Bulletin 40, no. 4 (January 1, 1988): 238-243.

Scholars@Duke

Pages