James Abbruzzese, MD

Professor of Medicine
D. C. I. Professor of Medical Oncology
Chief, Division of Medical Oncology
Member of the Duke Cancer Institute
Campus mail 440 Mudd Building, Box 3406, Durham, NC 27710
Email address james.abbruzzese@duke.edu

My research interests include the clinical study and treatment of pancreatic cancer.

In Their Words

Education and Training

  • Resident, Internal Medicine, Johns Hopkins University School of Medicine, 1979 - 1981
  • Intern, Internal Medicine, Johns Hopkins University School of Medicine, 1978 - 1979
  • M.D., University of Chicago, 1978

Publications

Ajani, JA, Roth, JA, Ryan, B, McMurtrey, M, Rich, TA, Jackson, DE, Abbruzzese, JL, Levin, B, DeCaro, L, and Mountain, C. "Evaluation of pre- and postoperative chemotherapy for resectable adenocarcinoma of the esophagus or gastroesophageal junction." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 8, no. 7 (July 1990): 1231-1238.

PMID
2358838
Full Text

Ajani, JA, Abbruzzese, JL, Faintuch, JS, Patt, YZ, Boman, BM, Jackson, DE, Levin, B, and Krakoff, IH. "A phase II study of trimetrexate therapy for metastatic colorectal carcinoma." Cancer investigation 8, no. 6 (January 1990): 619-621.

PMID
2149834
Full Text

Abbruzzese, JL, Amato, R, Schmidt, S, Raber, MN, and Frost, P. "Phase I clinical trial of cisplatin given i.v. with 5-fluorouracil and high-dose folinic acid." Cancer chemotherapy and pharmacology 26, no. 3 (January 1990): 159-162.

PMID
2357761
Full Text

Ajani, JA, Ota, DM, Grossie, VB, Abbruzzese, JL, Faintuch, JS, Patt, YZ, Jackson, DE, Levin, B, and Nishioka, K. "Evaluation of continuous-infusion alpha-difluoromethylornithine therapy for colorectal carcinoma." Cancer chemotherapy and pharmacology 26, no. 3 (January 1990): 223-226.

PMID
2113439
Full Text

Weeks, AE, Abbruzzese, JL, and Levin, B. "Current status of chemotherapy for colorectal cancer." Drug Therapy 19, no. 6 (December 1, 1989): 36-55.

Scholars@Duke

Abbruzzese, JL, Weeks, A, Raber, MN, Gravel, D, DuBrow, RA, Levin, B, Grem, J, and Chun, HG. "Phase I trial of semustine plus weekly fluorouracil and high-dose leucovorin calcium in patients with advanced colorectal cancer." JNCI Journal of the National Cancer Institute 81, no. 23 (December 1989): 1840-1842.

PMID
2585532
Full Text

Abbruzzese, JL, Schmidt, S, Raber, MN, Levy, JK, Castellanos, AM, Legha, SS, and Krakoff, IH. "Phase I trial of 1-(2'-deoxy-2'-fluoro-1-beta-D-arabinofuranosyl)-5-methyluracil (FMAU) terminated by severe neurologic toxicity." Investigational new drugs 7, no. 2-3 (July 1989): 195-201.

PMID
2793372
Full Text

Abbruzzese, JL, Levin, B, Ajani, JA, Faintuch, JS, Saks, S, Patt, YZ, Edwards, C, Ende, K, and Gutterman, JU. "Phase I trial of recombinant human gamma-interferon and recombinant human tumor necrosis factor in patients with advanced gastrointestinal cancer." Cancer research 49, no. 14 (July 1989): 4057-4061.

PMID
2500234
Scholars@Duke

Ajani, JA, Rios, AA, Ende, K, Abbruzzese, JL, Edwards, C, Faintuch, JS, Saks, S, Gutterman, JU, and Levin, B. "Phase I and II studies of the combination of recombinant human interferon-gamma and 5-fluorouracil in patients with advanced colorectal carcinoma." Journal of biological response modifiers 8, no. 2 (April 1989): 140-146.

PMID
2499663
Scholars@Duke

Abbruzzese, JL, and Levin, B. "Treatment of advanced colorectal cancer." Hematology/Oncology Clinics of North America 3, no. 1 (March 1989): 135-153. (Review)

PMID
2465291
Full Text

Pages