Jeffrey Crawford, MD

Professor of Medicine
George Barth Geller Distinguished Professor of Immunology
Member of the Duke Cancer Institute
Campus mail 443 Seeley G. Mudd Bldg, Durham, NC 27710
Phone (919) 681-9509
Email address crawf006@mc.duke.edu

1. Lung cancer/new treatment approaches.
2. Clinical trials of hematopoietic growth factors, biological agents and targeted drug development.
3. Cancer in the elderly and supportive care

Accomplishments

1. Lead Investigator of the U. S. multicenter, randomized trial of Filgrastim (G-CSF, Neupogen) to reduce the morbidity of chemotherapy-related neutropenia, leading to FDA approval 2/91.
2. Lead Investigator of the U. S. multicenter, randomized trial of Vinorelbine (Navelbine) in treatment of patients with advanced non small cell carcinoma of lung (NSCLC), leading to FDA approval 12/94.
3. Principal Investigator in initial phase I clinical trials of stem cell factor (SCF), megakaryocyte growth and development factor (MGDF), pegylated granulocyte-colony-stimulating factor and other novel hematopoietic growth factors.

In Their Words

Education and Training

  • M.D., Ohio State University, 1974

Publications

Mahtani, Reshma, Jeffrey Crawford, Sinéad M. Flannery, Tatiana Lawrence, Jennifer Schenfeld, and Prasad L. Gawade. “Prophylactic pegfilgrastim to prevent febrile neutropenia among patients receiving biweekly (Q2W) chemotherapy regimens: a systematic review of efficacy, effectiveness and safety.” Bmc Cancer 21, no. 1 (May 27, 2021): 621. https://doi.org/10.1186/s12885-021-08258-w.

PMID
34044798
Full Text

Tao, Jun, Aminah Jatoi, Jeffrey Crawford, Wendy W. T. Lam, James C. Ho, Xiaofei Wang, and Herbert Pang. “Role of dietary carbohydrates on risk of lung cancer.” Lung Cancer 155 (May 2021): 87–93. https://doi.org/10.1016/j.lungcan.2021.03.009.

PMID
33756357
Full Text

Hollen, Patricia J., Richard J. Gralla, Ryan D. Gentzler, Richard D. Hall, Bethany Coyne, Haiying Cheng, Balazs Halmos, et al. “Do Patients Regret Having Received Systemic Treatment for Advanced Non-Small Cell Lung Cancer: A Prospective Evaluation.” Oncologist 26, no. 3 (March 2021): 224–30. https://doi.org/10.1002/onco.13571.

PMID
33098189
Full Text

Ramalingam, Sendhilnathan, Michaela A. Dinan, and Jeffrey Crawford. “Treatment at Integrated Centers Might Bridge the Academic-Community Survival Gap in Patients With Metastatic Non-Small Cell Carcinoma of the Lung.” Clin Lung Cancer, January 7, 2021. https://doi.org/10.1016/j.cllc.2020.12.013.

PMID
33582071
Full Text

Epstein, Robert S., Upal K. Basu Roy, Matti Aapro, Tehseen Salimi, Donald Moran, JoAnn Krenitsky, Megan L. Leone-Perkins, Cynthia Girman, Courtney Schlusser, and Jeffrey Crawford. “Cancer Patients' Perspectives and Experiences of Chemotherapy-Induced Myelosuppression and Its Impact on Daily Life.” Patient Prefer Adherence 15 (2021): 453–65. https://doi.org/10.2147/PPA.S292462.

PMID
33658769
Full Text

Negrao, Marcelo V., Victoria M. Raymond, Richard B. Lanman, Jacqulyne P. Robichaux, Junqin He, Monique B. Nilsson, Patrick K. S. Ng, et al. “Molecular Landscape of BRAF-Mutant NSCLC Reveals an Association Between Clonality and Driver Mutations and Identifies Targetable Non-V600 Driver Mutations.” J Thorac Oncol 15, no. 10 (October 2020): 1611–23. https://doi.org/10.1016/j.jtho.2020.05.021.

PMID
32540409
Full Text

Epstein, Robert S., Matti S. Aapro, Upal K. Basu Roy, Tehseen Salimi, JoAnn Krenitsky, Megan L. Leone-Perkins, Cynthia Girman, Courtney Schlusser, and Jeffrey Crawford. “Patient Burden and Real-World Management of Chemotherapy-Induced Myelosuppression: Results from an Online Survey of Patients with Solid Tumors.” Adv Ther 37, no. 8 (August 2020): 3606–18. https://doi.org/10.1007/s12325-020-01419-6.

PMID
32642965
Full Text

Deveaux, April E., Dadong Zhang, Muthana Al Abo, Nadine J. Barrett, Rick A. Kittles, Kouros Owzar, Shannon J. McCall, et al. “Abstract B071: Genomic differences between non-small cell lung cancer (NSCLC) in African American and white patients.” In Poster Presentations  Proffered Abstracts. American Association for Cancer Research, 2020. https://doi.org/10.1158/1538-7755.disp18-b071.

Full Text

Deveaux, April E., Dadong Zhang, Muthana Al Abo, Nadine J. Barrett, Rick A. Kittles, Kouros Owzar, Shannon J. McCall, et al. “Genomic differences between non-small cell lung cancer (NSCLC) in African American and white patients.” In Cancer Epidemiology Biomarkers & Prevention, Vol. 29, 2020.

Scholars@Duke

Leighl, Natasha B., Mary Weber Redman, Naiyer A. Rizvi, Fred R. Hirsch, Philip C. Mack, Lawrence Howard Schwartz, James Lloyd Wade, et al. “SWOG S1400F (NCT03373760): A phase II study of durvalumab plus tremelimumab for previously treated patients with acquired resistance to PD-1 checkpoint inhibitor therapy and stage IV squamous cell lung cancer (Lung-MAP Sub-study).” In Journal of Clinical Oncology, Vol. 38, 2020.

Scholars@Duke

Pages