Julia Jarrard Scialla, MD

Associate Professor of Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt Street, Rm 7042, Durham, NC 27705
Phone (919) 668-8764
Email address julia.scialla@duke.edu

Dr. Scialla is an Associate Professor of Medicine in Nephrology at Duke University and a faculty member at the Duke Clinical Research Institute.  Dr. Scialla trained in Internal Medicine, Nephrology, and Clinical Epidemiology at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health.  Her research focuses on chronic kidney disease (CKD) epidemiology and prevention, with an emphasis on the role of metabolic complications and nutrition. Current studies are focused on treatment and prevention of abnormal phosphate homeostasis, acid-base physiology, diabetic and other forms of kidney disease, and outcomes in end-stage kidney disease. 

Dr. Scialla’s work engages a number of study designs including prospective cohort studies, observational comparative effectiveness studies, and patient-oriented physiologic studies. She has worked closely with multiple chronic disease cohorts including the Chronic Renal Insufficiency Cohort (CRIC) Study, the African American Study of Kidney Disease and Hypertension (AASK), the Jackson Heart Study (JHS), and secondary analyses in clinical trials. Studies in electronic health records (EHR) and registries have engaged dialysis EHR data, the United States Renal Data System, and public registries, such as the National Health and Nutrition Examination Survey. Physiologic studies include the Acid Base Complication in CKD Study, secondary analyses in the DASH Mechanism Study, and the newly launched MURDOCK Kidney Health Study.

Education and Training

  • Nephrology, Fellowship, Johns Hopkins University School of Medicine, 2006 - 2010
  • Residency, Internal Medicine, Johns Hopkins University School of Medicine, 2003 - 2006
  • M.H.S., Johns Hopkins Bloomberg School of Public Health, 2010
  • M.D., University of Pennsylvania, 2003

Publications

Khairallah, P, and Scialla, JJ. "Role of Acid-Base Homeostasis in Diabetic Kidney Disease." Current Diabetes Reports 17, no. 4 (April 2017): 28-null. (Review)

PMID
28343312
Full Text

Munoz Mendoza, J, Isakova, T, Cai, X, Bayes, LY, Faul, C, Scialla, JJ, Lash, JP, Chen, J, He, J, Navaneethan, S, Negrea, L, Rosas, SE, Kretzler, M, Nessel, L, Xie, D, Anderson, AH, Raj, DS, Wolf, M, and CRIC Study Investigators, . "Inflammation and elevated levels of fibroblast growth factor 23 are independent risk factors for death in chronic kidney disease." Kidney International 91, no. 3 (March 2017): 711-719.

PMID
28017325
Full Text

Shafi, T, Sozio, SM, Luly, J, Bandeen-Roche, KJ, St Peter, WL, Ephraim, PL, McDermott, A, Herzog, CA, Crews, DC, Scialla, JJ, Tangri, N, Miskulin, DC, Michels, WM, Jaar, BG, Zager, PG, Meyer, KB, Wu, AW, Boulware, LE, and DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, . "Antihypertensive medications and risk of death and hospitalizations in US hemodialysis patients: Evidence from a cohort study to inform hypertension treatment practices." Medicine 96, no. 5 (February 2017): e5924-null.

PMID
28151871
Full Text

Michels, WM, Jaar, BG, Ephraim, PL, Liu, Y, Miskulin, DC, Tangri, N, Crews, DC, Scialla, JJ, Shafi, T, Sozio, SM, Bandeen-Roche, K, Cook, CJ, Meyer, KB, Boulware, LE, and DEcIDE Network Patient Outcomes in End Stage Renal Disease Study Investigators, . "Intravenous iron administration strategies and anemia management in hemodialysis patients." Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association European Renal Association 32, no. 1 (January 2017): 173-181.

PMID
27604984
Full Text

Scialla, JJ, Asplin, J, Dobre, M, Chang, AR, Lash, J, Hsu, C-Y, Kallem, RR, Hamm, LL, Feldman, HI, Chen, J, Appel, LJ, Anderson, CAM, Wolf, M, and Chronic Renal Insufficiency Cohort Study Investigators, . "Higher net acid excretion is associated with a lower risk of kidney disease progression in patients with diabetes." Kidney International 91, no. 1 (January 2017): 204-215.

PMID
27914710
Full Text

Mehta, R, Cai, X, Lee, J, Scialla, JJ, Bansal, N, Sondheimer, JH, Chen, J, Hamm, LL, Ricardo, AC, Navaneethan, SD, Deo, R, Rahman, M, Feldman, HI, Go, AS, Isakova, T, Wolf, M, and Chronic Renal Insufficiency Cohort (CRIC) Study Investigators, . "Association of Fibroblast Growth Factor 23 With Atrial Fibrillation in Chronic Kidney Disease, From the Chronic Renal Insufficiency Cohort Study." Jama Cardiology 1, no. 5 (August 2016): 548-556.

PMID
27434583
Full Text

Gutiérrez, OM, Parsa, A, Isakova, T, Scialla, JJ, Chen, J, Flack, JM, Nessel, LC, Gupta, J, Bellovich, KA, Steigerwalt, S, Sondheimer, JH, Wright, JT, Feldman, HI, Kusek, JW, Lash, JP, and Wolf, M. "Genetic African Ancestry and Markers of Mineral Metabolism in CKD." Clinical Journal of the American Society of Nephrology : Cjasn 11, no. 4 (April 2016): 653-662.

PMID
26912553
Full Text

Suarez, JJ, Isakova, T, Anderson, CAM, Boulware, LE, Wolf, M, and Scialla, JJ. "Food Access, Chronic Kidney Disease, and Hypertension in the U.S." American Journal of Preventive Medicine 49, no. 6 (December 2015): 912-920.

PMID
26590940
Full Text

Chen, TK, Choi, MJ, Kao, WHL, Astor, BC, Scialla, JJ, Appel, LJ, Li, L, Lipkowitz, MS, Wolf, M, Parekh, RS, Winkler, CA, Estrella, MM, and Crews, DC. "Examination of Potential Modifiers of the Association of APOL1 Alleles with CKD Progression." Clinical Journal of the American Society of Nephrology : Cjasn 10, no. 12 (December 2015): 2128-2135.

PMID
26430087
Full Text

Isakova, T, Craven, TE, Scialla, JJ, Nickolas, TL, Schnall, A, Barzilay, J, Schwartz, AV, and Action to Control Cardiovascular Risk in Diabetes (ACCORD) Trial, . "Change in estimated glomerular filtration rate and fracture risk in the Action to Control Cardiovascular Risk in Diabetes Trial." Bone 78 (September 2015): 23-27.

PMID
25937184
Full Text

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