Julia Jarrard Scialla, MD

Adjunct Associate Professor in the Department of Medicine
Member in the Duke Clinical Research Institute
Campus mail 2400 Pratt Street, Rm 7042, Durham, NC 27705
Phone (919) 668-8764
Email address julia.scialla@duke.edu

Dr. Scialla is an Associate Professor of Medicine in Nephrology at Duke University and a faculty member at the Duke Clinical Research Institute.  Dr. Scialla trained in Internal Medicine, Nephrology, and Clinical Epidemiology at the Johns Hopkins University School of Medicine and the Johns Hopkins Bloomberg School of Public Health.  Her research focuses on chronic kidney disease (CKD) epidemiology and prevention, with an emphasis on the role of metabolic complications and nutrition. Current studies are focused on treatment and prevention of abnormal phosphate homeostasis, acid-base physiology, diabetic and other forms of kidney disease, and outcomes in end-stage kidney disease. 

Dr. Scialla’s work engages a number of study designs including prospective cohort studies, observational comparative effectiveness studies, and patient-oriented physiologic studies. She has worked closely with multiple chronic disease cohorts including the Chronic Renal Insufficiency Cohort (CRIC) Study, the African American Study of Kidney Disease and Hypertension (AASK), the Jackson Heart Study (JHS), and secondary analyses in clinical trials. Studies in electronic health records (EHR) and registries have engaged dialysis EHR data, the United States Renal Data System, and public registries, such as the National Health and Nutrition Examination Survey. Physiologic studies include the Acid Base Complication in CKD Study, secondary analyses in the DASH Mechanism Study, and the newly launched MURDOCK Kidney Health Study.

Education and Training

  • Nephrology, Fellowship, Johns Hopkins University School of Medicine, 2006 - 2010
  • Residency, Internal Medicine, Johns Hopkins University School of Medicine, 2003 - 2006
  • M.H.S., Johns Hopkins Bloomberg School of Public Health, 2010
  • M.D., University of Pennsylvania, 2003

Publications

Scialla, Julia J. “The balance of the evidence on acid-base homeostasis and progression of chronic kidney disease.” Kidney Int 88, no. 1 (July 2015): 9–11. https://doi.org/10.1038/ki.2015.87.

PMID
26126088
Full Text

Dobre, Mirela, Wei Yang, Qiang Pan, Lawrence Appel, Keith Bellovich, Jing Chen, Harold Feldman, et al. “Persistent high serum bicarbonate and the risk of heart failure in patients with chronic kidney disease (CKD): A report from the Chronic Renal Insufficiency Cohort (CRIC) study.” J Am Heart Assoc 4, no. 4 (April 20, 2015). https://doi.org/10.1161/JAHA.114.001599.

PMID
25896890
Full Text

Tangri, Navdeep, Dana C. Miskulin, Jing Zhou, Karen Bandeen-Roche, Wieneke M. Michels, Patti L. Ephraim, Aidan McDermott, et al. “Effect of intravenous iron use on hospitalizations in patients undergoing hemodialysis: a comparative effectiveness analysis from the DEcIDE-ESRD study.” Nephrol Dial Transplant 30, no. 4 (April 2015): 667–75. https://doi.org/10.1093/ndt/gfu349.

PMID
25366328
Full Text

Isakova, Tamara, Timothy E. Craven, Jungwha Lee, Julia J. Scialla, Huiliang Xie, Patricia Wahl, Santica M. Marcovina, Robert P. Byington, and Myles Wolf. “Fibroblast growth factor 23 and incident CKD in type 2 diabetes.” Clin J Am Soc Nephrol 10, no. 1 (January 7, 2015): 29–38. https://doi.org/10.2215/CJN.06190614.

PMID
25343949
Full Text

Scialla, Julia J., Rulan S. Parekh, Joseph A. Eustace, Brad C. Astor, Laura Plantinga, Bernard G. Jaar, Tariq Shafi, Josef Coresh, Neil R. Powe, and Michal L. Melamed. “Race, Mineral Homeostasis and Mortality in Patients with End-Stage Renal Disease on Dialysis.” Am J Nephrol 42, no. 1 (2015): 25–34. https://doi.org/10.1159/000438999.

PMID
26287973
Full Text

Miskulin, Dana C., Navdeep Tangri, Karen Bandeen-Roche, Jing Zhou, Aidan McDermott, Klemens B. Meyer, Patti L. Ephraim, et al. “Intravenous iron exposure and mortality in patients on hemodialysis.” Clin J Am Soc Nephrol 9, no. 11 (November 7, 2014): 1930–39. https://doi.org/10.2215/CJN.03370414.

PMID
25318751
Full Text

Scialla, Julia J., Jiannong Liu, Deidra C. Crews, Haifeng Guo, Karen Bandeen-Roche, Patti L. Ephraim, Navdeep Tangri, et al. “An instrumental variable approach finds no associated harm or benefit with early dialysis initiation in the United States.” Kidney Int 86, no. 4 (October 2014): 798–809. https://doi.org/10.1038/ki.2014.110.

PMID
24786707
Full Text

Jaar, Bernard G., Lili Zhang, Svetlana V. Chembrovich, Stephen M. Sozio, Tariq Shafi, Julia J. Scialla, Gordon F. Tomaselli, et al. “Incidental findings on cardiac computed tomography in incident hemodialysis patients: the predictors of arrhythmic and cardiovascular events in end-stage renal disease (PACE) study.” Bmc Nephrol 15 (May 1, 2014): 68. https://doi.org/10.1186/1471-2369-15-68.

PMID
24885570
Full Text

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