Karen Ama-Serwa Chachu, MD, PhD

Assistant Professor of Medicine
Campus mail 40 Duke Medicine Circle, Durham, NC 27710
Email address karen.chachu@duke.edu
In Their Words

Education and Training

  • Advanced Inflammatory Bowel Disease Fellowship, Medicine, University of Pennsylvania, 2014 - 2015
  • Gastroenterology Fellowship, Medicine, University of Pennsylvania, 2011 - 2015
  • Internal Medicine Residency, Medicine, University of Pennsylvania, 2009 - 2011
  • Ph.D., Washington University School of Medicine, 2009
  • M.D., Washington University School of Medicine, 2009

Publications

Papamichael, Konstantinos, Karen A. Chachu, Ravy K. Vajravelu, Byron P. Vaughn, Josephine Ni, Mark T. Osterman, and Adam S. Cheifetz. “Improved Long-term Outcomes of Patients With Inflammatory Bowel Disease Receiving Proactive Compared With Reactive Monitoring of Serum Concentrations of Infliximab.” Clinical Gastroenterology and Hepatology 15, no. 10 (October 2017): 1580-1588.e3. https://doi.org/10.1016/j.cgh.2017.03.031.

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Chachu, Karen A., Anna D. LoBue, David W. Strong, Ralph S. Baric, and Herbert W. Virgin. “Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection.” Plos Pathog 4, no. 12 (December 2008): e1000236. https://doi.org/10.1371/journal.ppat.1000236.

PMID
19079577
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Purtha, Whitney E., Karen A. Chachu, Herbert W. Virgin, and Michael S. Diamond. “Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling.” J Virol 82, no. 22 (November 2008): 10964–74. https://doi.org/10.1128/JVI.01646-08.

PMID
18786989
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Chachu, Karen A., David W. Strong, Anna D. LoBue, Christiane E. Wobus, Ralph S. Baric, and Herbert W. Virgin. “Antibody is critical for the clearance of murine norovirus infection.” J Virol 82, no. 13 (July 2008): 6610–17. https://doi.org/10.1128/JVI.00141-08.

PMID
18417579
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Thackray, Larissa B., Christiane E. Wobus, Karen A. Chachu, Bo Liu, Eric R. Alegre, Kenneth S. Henderson, Scott T. Kelley, and Herbert W. Virgin. “Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence.” J Virol 81, no. 19 (October 2007): 10460–73. https://doi.org/10.1128/JVI.00783-07.

PMID
17652401
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Au, Nora, Elke Kuester-Schoeck, Veena Mandava, Laura E. Bothwell, Susan P. Canny, Karen Chachu, Sierra A. Colavito, et al. “Genetic composition of the Bacillus subtilis SOS system.” J Bacteriol 187, no. 22 (November 2005): 7655–66. https://doi.org/10.1128/JB.187.22.7655-7666.2005.

PMID
16267290
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