Karen Ama-Serwa Chachu, MD, PhD

Assistant Professor of Medicine

Campus mail 40 Duke Medicine Circle, Durham, NC 27710

Email address karen.chachu@duke.edu

In Their Words

Education and Training

Advanced Inflammatory Bowel Disease Fellowship, Medicine, University of Pennsylvania, 2014 - 2015
Gastroenterology Fellowship, Medicine, University of Pennsylvania, 2011 - 2015
Internal Medicine Residency, Medicine, University of Pennsylvania, 2009 - 2011
Ph.D., Washington University School of Medicine, 2009
M.D., Washington University School of Medicine, 2009

Grants

Publications

Papamichael, Konstantinos, Karen A. Chachu, Ravy K. Vajravelu, Byron P. Vaughn, Josephine Ni, Mark T. Osterman, and Adam S. Cheifetz. “Improved Long-term Outcomes of Patients With Inflammatory Bowel Disease Receiving Proactive Compared With Reactive Monitoring of Serum Concentrations of Infliximab.” Clinical Gastroenterology and Hepatology 15, no. 10 (October 2017): 1580-1588.e3. https://doi.org/10.1016/j.cgh.2017.03.031.

Full Text

Chachu, Karen A., Anna D. LoBue, David W. Strong, Ralph S. Baric, and Herbert W. Virgin. “Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection.” Plos Pathog 4, no. 12 (December 2008): e1000236. https://doi.org/10.1371/journal.ppat.1000236.

PMID

19079577

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Purtha, Whitney E., Karen A. Chachu, Herbert W. Virgin, and Michael S. Diamond. “Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling.” J Virol 82, no. 22 (November 2008): 10964–74. https://doi.org/10.1128/JVI.01646-08.

PMID

18786989

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Chachu, Karen A., David W. Strong, Anna D. LoBue, Christiane E. Wobus, Ralph S. Baric, and Herbert W. Virgin. “Antibody is critical for the clearance of murine norovirus infection.” J Virol 82, no. 13 (July 2008): 6610–17. https://doi.org/10.1128/JVI.00141-08.

PMID

18417579

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Thackray, Larissa B., Christiane E. Wobus, Karen A. Chachu, Bo Liu, Eric R. Alegre, Kenneth S. Henderson, Scott T. Kelley, and Herbert W. Virgin. “Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence.” J Virol 81, no. 19 (October 2007): 10460–73. https://doi.org/10.1128/JVI.00783-07.

PMID

17652401

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Au, Nora, Elke Kuester-Schoeck, Veena Mandava, Laura E. Bothwell, Susan P. Canny, Karen Chachu, Sierra A. Colavito, et al. “Genetic composition of the Bacillus subtilis SOS system.” J Bacteriol 187, no. 22 (November 2005): 7655–66. https://doi.org/10.1128/JB.187.22.7655-7666.2005.

PMID

16267290

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