Cardiology

Kenneth Daniel Poss, PhD

Professor of Cell Biology
James B. Duke Distinguished Professor of Cell Biology
Professor in Medicine
Professor of Biology
Associate of the Duke Initiative for Science & Society
Member of the Duke Cancer Institute
Director of the Duke Regeneration Center
Campus mail 307 Research Drive, Nanaline Bldg Room 466 A, Durham, NC 27710
Phone (919) 681-8457
Email address ken.poss@duke.edu

Modeling disease in zebrafish
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology

Education and Training

  • Postdoctoral Fellow, Cardiology, Children's Hospital, 2000 - 2003
  • Research Fellow, University of Utah, 1998 - 2000
  • Ph.D., Massachusetts Institute of Technology, 1998

Grants

Publications

Hayden, Luke D., Kenneth D. Poss, Alessandro De Simone, and Stefano Di Talia. “Mathematical modeling of Erk activity waves in regenerating zebrafish scales.” Biophys J 120, no. 19 (October 5, 2021): 4287–97. https://doi.org/10.1016/j.bpj.2021.05.004.

PMID
34022234
Full Text

Chen, Anzhi, Yanchao Han, and Kenneth D. Poss. “Regulation of zebrafish fin regeneration by vitamin D signaling.” Dev Dyn 250, no. 9 (September 2021): 1330–39. https://doi.org/10.1002/dvdy.261.

PMID
33064344
Full Text

Gemberling, Matthew P., Keith Siklenka, Erica Rodriguez, Katherine R. Tonn-Eisinger, Alejandro Barrera, Fang Liu, Ariel Kantor, et al. “Transgenic mice for in vivo epigenome editing with CRISPR-based systems.” Nat Methods 18, no. 8 (August 2021): 965–74. https://doi.org/10.1038/s41592-021-01207-2.

PMID
34341582
Full Text

Tseng, Tzu-Lun, Ying-Ting Wang, Chang-Yu Tsao, Yi-Teng Ke, Yi-Ching Lee, Hwei-Jan Hsu, Kenneth D. Poss, and Chen-Hui Chen. “The RNA helicase Ddx52 functions as a growth switch in juvenile zebrafish.” Development, July 5, 2021. https://doi.org/10.1242/dev.199578.

PMID
34224557
Full Text

Peng, Xiangwen, Kaa Seng Lai, Peilu She, Junsu Kang, Tingting Wang, Guobao Li, Yating Zhou, et al. “Induction of Wnt signaling antagonists and p21-activated kinase enhances cardiomyocyte proliferation during zebrafish heart regeneration.” J Mol Cell Biol 13, no. 1 (April 10, 2021): 41–58. https://doi.org/10.1093/jmcb/mjaa046.

PMID
33582796
Full Text

Pronobis, Mira I., Susan Zheng, Sumeet Pal Singh, Joseph A. Goldman, and Kenneth D. Poss. “In vivo proximity labeling identifies cardiomyocyte protein networks during zebrafish heart regeneration.” Elife 10 (March 25, 2021). https://doi.org/10.7554/eLife.66079.

PMID
33764296
Full Text

Ye, Lihua, Munhyung Bae, Chelsi D. Cassilly, Sairam V. Jabba, Daniel W. Thorpe, Alyce M. Martin, Hsiu-Yi Lu, et al. “Enteroendocrine cells sense bacterial tryptophan catabolites to activate enteric and vagal neuronal pathways.” Cell Host Microbe 29, no. 2 (February 10, 2021): 179-196.e9. https://doi.org/10.1016/j.chom.2020.11.011.

PMID
33352109
Full Text

De Simone, Alessandro, Maya N. Evanitsky, Luke Hayden, Ben D. Cox, Julia Wang, Valerie A. Tornini, Jianhong Ou, Anna Chao, Kenneth D. Poss, and Stefano Di Talia. “Control of osteoblast regeneration by a train of Erk activity waves.” Nature 590, no. 7844 (February 2021): 129–33. https://doi.org/10.1038/s41586-020-03085-8.

PMID
33408418
Full Text

Mukherjee, Debanjan, Ganesh Wagh, Mayssa H. Mokalled, Zacharias Kontarakis, Amy L. Dickson, Amey Rayrikar, Stefan Günther, Kenneth D. Poss, Didier Y. R. Stainier, and Chinmoy Patra. “Ccn2a is an injury-induced matricellular factor that promotes cardiac regeneration in zebrafish.” Development (Cambridge, England) 148, no. 2 (January 18, 2021). https://doi.org/10.1242/dev.193219.

PMID
33234717
Full Text

Pages