Cardiology

Kenneth Daniel Poss, PhD

Professor of Cell Biology
James B. Duke Professor of Cell Biology
Professor in Medicine
Professor of Biology
Associate of the Duke Initiative for Science & Society
Member of the Duke Cancer Institute
Director of the Regeneration Next Initiative
Campus mail 307 Research Drive, Nanaline Bldg Room 466 A, Durham, NC 27710
Phone (919) 681-8457
Email address k.poss@cellbio.duke.edu

Modeling disease in zebrafish
Genetic approaches to organ regeneration
Cardiac regeneration
Appendage regeneration
Developmental biology

Education and Training

  • Postdoctoral Fellow, Cardiology, Children's Hospital, 2000 - 2003
  • Research Fellow, University of Utah, 1998 - 2000
  • Ph.D., Massachusetts Institute of Technology, 1998

Grants

Publications

Han, Y, Chen, A, Umansky, K-B, Oonk, KA, Choi, W-Y, Dickson, AL, Ou, J, Cigliola, V, Yifa, O, Cao, J, Tornini, VA, Cox, BD, Tzahor, E, and Poss, KD. "Vitamin D Stimulates Cardiomyocyte Proliferation and Controls Organ Size and Regeneration in Zebrafish." Developmental Cell 48, no. 6 (March 2019): 853-863.e5.

PMID
30713073
Full Text

Cox, BD, De Simone, A, Tornini, VA, Singh, SP, Di Talia, S, and Poss, KD. "In Toto Imaging of Dynamic Osteoblast Behaviors in Regenerating Skeletal Bone." Current Biology : Cb 28, no. 24 (December 2018): 3937-3947.e4.

PMID
30503623
Full Text

Mokalled, MH, and Poss, KD. "A Regeneration Toolkit." Developmental Cell 47, no. 3 (November 2018): 267-280. (Review)

PMID
30399333
Full Text

Cao, J, and Poss, KD. "The epicardium as a hub for heart regeneration." Nature Reviews. Cardiology 15, no. 10 (October 2018): 631-647. (Review)

PMID
29950578
Full Text

Walton, EM, Cronan, MR, Cambier, CJ, Rossi, A, Marass, M, Foglia, MD, Brewer, WJ, Poss, KD, Stainier, DYR, Bertozzi, CR, and Tobin, DM. "Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling." Cell Host & Microbe 24, no. 4 (October 2018): 514-525.e6.

PMID
30308157
Full Text

Karra, R, Foglia, MJ, Choi, W-Y, Belliveau, C, DeBenedittis, P, and Poss, KD. "Vegfaa instructs cardiac muscle hyperplasia in adult zebrafish." Proceedings of the National Academy of Sciences of the United States of America 115, no. 35 (August 13, 2018): 8805-8810.

PMID
30104362
Full Text

Wopat, S, Bagwell, J, Sumigray, KD, Dickson, AL, Huitema, LFA, Poss, KD, Schulte-Merker, S, and Bagnat, M. "Spine Patterning Is Guided by Segmentation of the Notochord Sheath." Cell Reports 22, no. 8 (February 2018): 2026-2038.

PMID
29466731
Full Text

Yang, XH, Nadadur, RD, Hilvering, CR, Bianchi, V, Werner, M, Mazurek, SR, Gadek, M, Shen, KM, Goldman, JA, Tyan, L, Bekeny, J, Hall, JM, Lee, N, Perez-Cervantes, C, Burnicka-Turek, O, Poss, KD, Weber, CR, de Laat, W, Ruthenburg, AJ, and Moskowitz, IP. "Transcription-factor-dependent enhancer transcription defines a gene regulatory network for cardiac rhythm." Elife 6 (December 27, 2017).

PMID
29280435
Full Text

Chen, C-H, and Poss, KD. "Regeneration Genetics." Annual Review of Genetics 51 (November 2017): 63-82. (Review)

PMID
28853919
Full Text

Cao, J, Wang, J, Jackman, CP, Cox, AH, Trembley, MA, Balowski, JJ, Cox, BD, De Simone, A, Dickson, AL, Di Talia, S, Small, EM, Kiehart, DP, Bursac, N, and Poss, KD. "Tension Creates an Endoreplication Wavefront that Leads Regeneration of Epicardial Tissue." Developmental Cell 42, no. 6 (September 2017): 600-615.e4.

PMID
28950101
Full Text

Pages