Kimberly Lynn Blackwell, MD

Professor of Medicine
Assistant Professor in Radiation Oncology
Member of the Duke Cancer Institute
Campus mail Duke Box 3893, Durham, NC 27710
Phone (919) 668-1748
Email address black034@mc.duke.edu

Breast cancer angiogenesis
Breast cancer in younger women
Hormonal therapy
Neoadjurant therapy for breast cancer

Current Clinical Investigations

Principal Investigator, A Phase I-II Study of Neoadjuvant Evacet/Paclitaxel/Hyperthermia in Locally Advanced Breast Cancer Patients.

Investigator, Development of Screening Markers for Breast Cancer using Circulating Immune Complexes: Collaborative Study with Diagen Medical Technologies.

Principal Investigator, Use of Plasma D-Dimer as a Predictive Marker in Colorectal Carcinoma: Correlative Science Study with Genentech, Inc.

Principal Investigator, A randomized, Phase II study of gabapentin or glutamine to prevent the peripheral neuropathy/myalgia associated with weekly taxol administration in metastatic breast and lung cancer.

Investigator, A Phase 2, Randomized, Double-Masked, Multicenter Study of Two Dose Levels of ERA-923 for the treatment of Metastatic Breast Cancer in Postmenopausal Women who have failed Tamoxifen therapy. Genetics Institute.

Investigator, A Phase I Study of Combined Doxil/Hyperthermia in Stage IV Breast Cancer.

Education and Training

  • Fellow In Hematology Oncology, Medicine, Duke University, 1997 - 2000
  • Medical Resident, Medicine, Duke University, 1994 - 1997
  • M.D., Mayo School of Health Sciences, 1994

Publications

Tripathy, D, Harnden, K, Blackwell, K, and Robson, M. "Next generation sequencing and tumor mutation profiling: are we ready for routine use in the oncology clinic?." BMC Medicine 12, no. 1 (December 2014).

Full Text

Shelby, RA, Edmond, SN, Wren, AA, Keefe, FJ, Peppercorn, JM, Marcom, PK, Blackwell, KL, and Kimmick, GG. "Self-efficacy for coping with symptoms moderates the relationship between physical symptoms and well-being in breast cancer survivors taking adjuvant endocrine therapy." Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 22, no. 10 (October 2014): 2851-2859.

PMID
24821365
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Zagar, TM, Vujaskovic, Z, Formenti, S, Rugo, H, Muggia, F, O'Connor, B, Myerson, R, Stauffer, P, Hsu, IC, Diederich, C, Straube, W, Boss, MK, Boico, A, Craciunescu, O, Maccarini, P, Needham, D, Borys, N, Blackwell, KL, and Dewhirst, MW. "Two phase I dose-escalation/pharmacokinetics studies of low temperature liposomal doxorubicin (LTLD) and mild local hyperthermia in heavily pretreated patients with local regionally recurrent breast cancer." International journal of hyperthermia : the official journal of European Society for Hyperthermic Oncology, North American Hyperthermia Group 30, no. 5 (August 2014): 285-294.

PMID
25144817
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Aapro, M, Andre, F, Blackwell, K, Calvo, E, Jahanzeb, M, Papazisis, K, Porta, C, Pritchard, K, and Ravaud, A. "Adverse event management in patients with advanced cancer receiving oral everolimus: focus on breast cancer." Annals of Oncology 25, no. 4 (April 1, 2014): 763-773.

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Malin, D, Strekalova, E, Petrovic, V, Deal, AM, Al Ahmad, A, Adamo, B, Miller, CR, Ugolkov, A, Livasy, C, Fritchie, K, Hamilton, E, Blackwell, K, Geradts, J, Ewend, M, Carey, L, Shusta, EV, Anders, CK, and Cryns, VL. "αB-crystallin: a novel regulator of breast cancer metastasis to the brain." Clin Cancer Res 20, no. 1 (January 1, 2014): 56-67.

PMID
24132917
Full Text

Malin, D, Strekalova, E, Petrovic, V, Deal, AM, Ahmad, AA, Adamo, B, Miller, CR, Ugolkov, A, Livasy, C, Fritchie, K, Hamilton, E, Blackwell, K, Geradts, J, Ewend, M, Carey, L, Shusta, EV, Anders, CK, and Cryns, VL. "αB-crystallin: a novel regulator of breast cancer metastasis to the brain." Clinical cancer research : an official journal of the American Association for Cancer Research 20, no. 1 (2014): 56-67.

Full Text

Hamilton, EP, Kimmick, GG, Hopkins, JO, Marcom, PK, Rocha, G, Welch, RA, Broadwater, GJL, and Blackwell, KL. "Nab-paclitaxel/bevacizumab/carboplatin chemotherapy in first-line triple negative metastatic breast cancer." Clinical Breast Cancer 13, no. 6 (December 1, 2013): 416-420.

Full Text

Hamilton, E, Kimmick, G, Hopkins, J, Marcom, PK, Rocha, G, Welch, R, Broadwater, G, and Blackwell, K. "Nab-paclitaxel/bevacizumab/carboplatin chemotherapy in first-line triple negative metastatic breast cancer." Clin Breast Cancer 13, no. 6 (December 2013): 416-420.

PMID
24099649
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Gucalp, A, Tolaney, S, Isakoff, SJ, Ingle, JN, Liu, MC, Carey, LA, Blackwell, K, Rugo, H, Nabell, L, Forero, A, Stearns, V, Doane, AS, Danso, M, Moynahan, ME, Momen, LF, Gonzalez, JM, Akhtar, A, Giri, DD, Patil, S, Feigin, KN, Hudis, CA, Traina, TA, and Translational Breast Cancer Research Consortium (TBCRC 011), . "Phase II trial of bicalutamide in patients with androgen receptor-positive, estrogen receptor-negative metastatic Breast Cancer." Clin Cancer Res 19, no. 19 (October 1, 2013): 5505-5512.

PMID
23965901
Full Text

Jones, LW, Fels, DR, West, M, Allen, JD, Broadwater, G, Barry, WT, Wilke, LG, Masko, E, Douglas, PS, Dash, RC, Povsic, TJ, Peppercorn, J, Marcom, PK, Blackwell, KL, Kimmick, G, Turkington, TG, and Dewhirst, MW. "Modulation of circulating angiogenic factors and tumor biology by aerobic training in breast cancer patients receiving neoadjuvant chemotherapy." Cancer Prev Res (Phila) 6, no. 9 (September 2013): 925-937.

PMID
23842792
Full Text

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