Dr. Hauser has a strong interest in ocular genetics. Genomic studies at the Center for Human Genetics have identified multiple linkage peaks and susceptibility genes in primary open angle glaucoma (POAG) and age related macular degeneration (AMD). Dr. Hauser has recently accepted a 20% appointment at the Singapore Eye Research INstitute and the Duke/National University of Singapore. In collaboration with multiple collaborators in Singapore, and Dr. Rand Allingham at the Duke Eye Center, Dr. Hauser is currently conducting a genome wide association study for glaucoma in individuals of African ancestry. These investigations include large datasets collected in Ghana, Nigeria, and South Africa.
Dr. Hauser is also involved in collaborative investigations into the genetics of post-tramatic stress disorder in US veterans from Iraq and Afghanistan. Major collaborators include Dr. Allison Ashley Koch, Dr. Jean Beckham, Dr. Christine Marx and the MIRECC Collaborative group at the Durham Veteran's Administration. We have published a genome wide association study, as well as numerous investigations into candidate genes. Epigenomic DNA methylation analysis and gene expression analysis of 3500 individuals is currently ongoing.
Education and Training
- Ph.D., Johns Hopkins University, 1990
- Genetic and Genomics Training Grant
- Molecular Mechanisms of Exfoliation Glaucoma
- Single nuclear RNAseq to characterize glaucoma risk genes
- IPA - Garrett, Melanie - MIRECC
- IPA-Allison Ashley-Koch, MIRECC
- IPA-Ashley-Koch, MVP
- MVP IPA - Xue Jun Qin
- IPA MIRECC - Michelle Dennis
- IPA MIRECC - Michael Hauser
- Eyes of Africa: The Genetics of Blindness
- Longevity and Stress in African American Families