Hematologic Malignancies and Cellular Therapy

Mitchell Eric Horwitz, MD

Professor of Medicine
Member of the Duke Cancer Institute
Affiliate of the Regeneration Next Initiative
Campus mail 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
Phone (919) 668-1000
Email address mitchell.horwitz@duke.edu

Allogeneic stem cell transplantation using umbilical cord blood grafts; Allogenic stem cell transplantation for Sickle Cell Disease; Prevention of acute graft versus host disease through donor stem cell graft manipulation; Improving immune recovery following alternative donor stem cell transplantation using donor graft manipulation or third party thymus transplantation.

In Their Words

Education and Training

  • Medical Resident, Medicine, Northwestern University, 1992 - 1995
  • M.D., Rush University, 1992

Grants

Publications

Hourigan, Christopher S., Laura W. Dillon, Gege Gui, Brent R. Logan, Mingwei Fei, Jack Ghannam, Yuesheng Li, et al. “Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease.” J Clin Oncol, December 20, 2019, JCO1903011. https://doi.org/10.1200/JCO.19.03011.

PMID
31860405
Full Text

Saullo, Jennifer L., Yanhong Li, Julia A. Messina, Jillian Thompson, Tara Dalton, Vinay K. Giri, Shelby D. Reed, et al. “Cytomegalovirus in Allogeneic Hematopoietic Transplantation: Impact on Costs and Clinical Outcomes Using a Preemptive Strategy.” Biol Blood Marrow Transplant, November 9, 2019. https://doi.org/10.1016/j.bbmt.2019.11.005.

PMID
31712193
Full Text

Cardones, Adela R., Keith M. Sullivan, Cindy Green, Nelson J. Chao, Krista Rowe-Nichols, Lionel L. Bañez, Claude S. Burton, et al. “Interrater Reliability of Clinical Grading Measures for Cutaneous Chronic Graft-vs-Host Disease.” Jama Dermatol 155, no. 7 (July 1, 2019): 833–37. https://doi.org/10.1001/jamadermatol.2018.5459.

PMID
30994873
Full Text

Maung, Ko K., and Mitchell E. Horwitz. “Current and future perspectives on allogeneic transplantation using ex vivo expansion or manipulation of umbilical cord blood cells.” Int J Hematol 110, no. 1 (July 2019): 50–58. https://doi.org/10.1007/s12185-019-02670-6.

PMID
31123927
Full Text

Chen, Yi-Bin, Jennifer Le-Rademacher, Ruta Brazauskas, Deidre M. Kiefer, Mehdi Hamadani, John F. DiPersio, Mark R. Litzow, et al. “Plerixafor alone for the mobilization and transplantation of HLA-matched sibling donor hematopoietic stem cells.” Blood Adv 3, no. 6 (March 26, 2019): 875–83. https://doi.org/10.1182/bloodadvances.2018027599.

PMID
30890544
Full Text

Horwitz, Mitchell E., Stephen Wease, Beth Blackwell, David Valcarcel, Francesco Frassoni, Jaap Jan Boelens, Stefan Nierkens, et al. “Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide.” J Clin Oncol 37, no. 5 (February 10, 2019): 367–74. https://doi.org/10.1200/JCO.18.00053.

PMID
30523748
Full Text

Foster, Yevgeniya, Michael J. Grant, Samantha M. Thomas, Blake Cameron, Doug Raiff, Kelly Corbet, Christopher Ferreri, and Mitchell E. Horwitz. “Treatment with Foscarnet after Allogeneic Hematopoietic-Cell Transplant (AlloHCT) Is Associated with Long-Term Loss of Renal Function.” In Blood, 132:4594–4594. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-113189.

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Boelens, Jaap Jan, Coco de Koning, Mitchell E. Horwitz, Guillermo Sanz, Madan Jagasia, John E. Wagner, Patrick J. Stiff, Rabi Hanna, Daniela Cilloni, and Stefan Nierkens. “Rapid and Robust CD4+ and CD8+ T-, NK-, B- and Monocyte Cell Reconstitution after Nicotinamide-Expanded Cord Blood Transplantation.” In Blood, 132:2123–2123. American Society of Hematology, 2018. https://doi.org/10.1182/blood-2018-99-116700.

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