Hematologic Malignancies and Cellular Therapy

Mitchell Eric Horwitz, MD

Professor of Medicine
Member of the Duke Cancer Institute
Affiliate of the Duke Regeneration Center
Campus mail 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
Phone (919) 668-1000
Email address mitchell.horwitz@duke.edu

Allogeneic stem cell transplantation using umbilical cord blood grafts; Allogenic stem cell transplantation for Sickle Cell Disease; Prevention of acute graft versus host disease through donor stem cell graft manipulation; Improving immune recovery following alternative donor stem cell transplantation using donor graft manipulation or third party thymus transplantation.

In Their Words

Education and Training

  • Medical Resident, Medicine, Northwestern University, 1992 - 1995
  • M.D., Rush University, 1992

Grants

Publications

Brunstein, Claudio G., Paul V. O’Donnell, Brent Logan, Peter Dawson, Luciano Costa, Corey Cutler, Michael Craig, et al. “Impact of Center Experience with Donor Type on Outcomes: A Secondary Analysis, Blood and Marrow Transplant Clinical Trials Network 1101Open for Accrual June 2012Open for Accrual June 2012.” Transplant Cell Ther, April 4, 2022. https://doi.org/10.1016/j.jtct.2022.03.024.

PMID
35390529
Full Text

Wolfe, Heather R., Mitchell E. Horwitz, and Lindsay A. M. Rein. “The Use of Allogeneic Hematopoietic Stem Cell Transplantation in Primary Myelofibrosis.” J Pers Med 12, no. 4 (April 2, 2022). https://doi.org/10.3390/jpm12040571.

PMID
35455686
Full Text

Sung, Anthony D., Vinay K. Giri, Helen Tang, Krista Rowe Nichols, Meagan V. Lew, Lauren Bohannon, Yi Ren, et al. “Home-Based Hematopoietic Cell Transplantation in the United States.” Transplant Cell Ther 28, no. 4 (April 2022): 207.e1-207.e8. https://doi.org/10.1016/j.jtct.2022.01.015.

PMID
35066211
Full Text

Smith, Patrick J., Meagan Lew, Yen Lowder, Kristi Romero, Jillian C. Thompson, Lauren Bohannon, Alyssa Pittman, et al. “Cognitive impairment in candidates for allogeneic hematopoietic stem cell transplantation.” In Bone Marrow Transplant, 57:89–94, 2022. https://doi.org/10.1038/s41409-021-01470-z.

PMID
34667271
Full Text

Koning, Coco de, Weiyang Tao, Amelia Lacna, Karin van Veghel, Mitchell E. Horwitz, Guillermo Sanz, Madan H. Jagasia, et al. “Lymphoid and myeloid immune cell reconstitution after nicotinamide-expanded cord blood transplantation.” Bone Marrow Transplant 56, no. 11 (November 2021): 2826–33. https://doi.org/10.1038/s41409-021-01417-4.

PMID
34312498
Full Text

Horwitz, Mitchell E., Patrick J. Stiff, Corey Cutler, Claudio Brunstein, Rabi Hanna, Richard T. Maziarz, Andrew R. Rezvani, et al. “Omidubicel vs standard myeloablative umbilical cord blood transplantation: results of a phase 3 randomized study.” Blood 138, no. 16 (October 21, 2021): 1429–40. https://doi.org/10.1182/blood.2021011719.

PMID
34157093
Full Text

Herrera, Alex F., Kwang Woo Ahn, Carlos Litovich, Yue Chen, Amer Assal, Qaiser Bashir, Ruthee-Lu Bayer, et al. “Autologous and allogeneic hematopoietic cell transplantation for diffuse large B-cell lymphoma-type Richter syndrome.” Blood Adv 5, no. 18 (September 28, 2021): 3528–39. https://doi.org/10.1182/bloodadvances.2021004865.

PMID
34496026
Full Text

Islam, Prioty, Helen Tang, Haesu Jin, Felicia Cao, Lauren M. Bohannon, Yi Ren, Nelson J. Chao, et al. “Female Sex Is Associated with Improved Long-Term Survival Following Allogeneic Hematopoietic Stem Cell Transplantation.” Transplant Cell Ther 27, no. 9 (September 2021): 784.e1-784.e7. https://doi.org/10.1016/j.jtct.2021.06.012.

PMID
34146734
Full Text

Bohannon, Lauren, Helen Tang, Kristin Page, Yi Ren, Sin-Ho Jung, Alexandra Artica, Anne Britt, et al. “Decreased Mortality in 1-Year Survivors of Umbilical Cord Blood Transplant vs. Matched Related or Matched Unrelated Donor Transplant in Patients with Hematologic Malignancies.” Transplant Cell Ther 27, no. 8 (August 2021): 669.e1-669.e8. https://doi.org/10.1016/j.jtct.2021.05.002.

PMID
33991725
Full Text

Ponce, Doris M., Ioannis Politikos, Amin Alousi, Paul A. Carpenter, Filippo Milano, Margaret L. MacMillan, Juliet N. Barker, Mitchell E. Horwitz, and Mitchell E. American Society for Transplantation and Cellular Therapy Cord Blood Special Interest Group. “Guidelines for the Prevention and Management of Graft-versus-Host Disease after Cord Blood Transplantation.” Transplant Cell Ther 27, no. 7 (July 2021): 540–44. https://doi.org/10.1016/j.jtct.2021.03.012.

PMID
34210500
Full Text

Pages