Hematologic Malignancies and Cellular Therapy

Mitchell Eric Horwitz, MD

Professor of Medicine
Member of the Duke Cancer Institute
Affiliate of the Regeneration Next Initiative
Campus mail 2400 Pratt St., Suite 5000, Durham, NC 27705
Phone (919) 668-1012
Email address mitchell.horwitz@duke.edu

Allogeneic stem cell transplantation using umbilical cord blood grafts; Allogenic stem cell transplantation for Sickle Cell Disease; Prevention of acute graft versus host disease through donor stem cell graft manipulation; Improving immune recovery following alternative donor stem cell transplantation using donor graft manipulation or third party thymus transplantation.

In Their Words

Education and Training

  • Medical Resident, Medicine, Northwestern University, 1992 - 1995
  • M.D., Rush University, 1992

Grants

Publications

Horwitz, ME, Wease, S, Blackwell, B, Valcarcel, D, Frassoni, F, Boelens, JJ, Nierkens, S, Jagasia, M, Wagner, JE, Kuball, J, Koh, LP, Majhail, NS, Stiff, PJ, Hanna, R, Hwang, WYK, Kurtzberg, J, Cilloni, D, Freedman, LS, Montesinos, P, and Sanz, G. "Phase I/II Study of Stem-Cell Transplantation Using a Single Cord Blood Unit Expanded Ex Vivo With Nicotinamide." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology (December 4, 2018): JCO1800053-null.

PMID
30523748
Full Text

Spellecy, R, Tarima, S, Denzen, E, Moore, H, Abhyankar, S, Dawson, P, Foley, A, Gersten, I, Horwitz, M, Idossa, L, Joffe, S, Kamani, N, King, R, Lazaryan, A, Morris, L, Horowitz, MM, and Majhail, NS. "Easy-to-Read Informed Consent Form for Hematopoietic Cell Transplantation Clinical Trials: Results from the Blood and Marrow Transplant Clinical Trials Network 1205 Study." Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 24, no. 10 (October 2018): 2145-2151.

PMID
29679770
Full Text

Micallef, IN, Stiff, PJ, Nademanee, AP, Maziarz, RT, Horwitz, ME, Stadtmauer, EA, Kaufman, JL, McCarty, JM, Vargo, R, Cheverton, PD, Struijs, M, Bolwell, B, and DiPersio, JF. "Plerixafor Plus Granulocyte Colony-Stimulating Factor for Patients with Non-Hodgkin Lymphoma and Multiple Myeloma: Long-Term Follow-Up Report." Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 24, no. 6 (June 2018): 1187-1195.

PMID
29410180
Full Text

Sullivan, KM, Horwitz, M, Osunkwo, I, Shah, N, and Strouse, JJ. "Shared Decision-Making in Hematopoietic Stem Cell Transplantation for Sickle Cell Disease." Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 24, no. 5 (May 2018): 883-884.

PMID
29649619
Full Text

Jones, RB, Martinez, C, Majhail, NS, Prestegaard, M, Maiers, M, Horwitz, M, and Komanduri, K. "Stem Cell Transplantation and Informatics: Current Considerations." Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 24, no. 4 (April 2018): 659-665. (Review)

PMID
29288819
Full Text

Parikh, S, Brochstein, JA, Wease, S, Martin, PL, Horwitz, ME, Schwarzbach, A, and Kurtzberg, J. "A Novel Therapy for Sickle Cell Disease (SCD): Co-Transplantation of Nicord (R) [Ex Vivo Expanded Umbilical Cord Blood (UCB) Progenitor Cells with Nicotinamide] and an Unmanipulated Unrelated UCB Graft Leads to Successful Engraftment and Cure of Severe SCD." March 2018.

Scholars@Duke

Horwitz, ME, Cilloni, D, Valcarcel, D, Frassoni, F, Boelens, J-J, Jagasia, M, Wagner, JE, Kuball, J, Koh, LP, Majhail, NS, Stiff, PJ, Hanna, R, Maziarz, RT, Hwang, WYK, Montesinos, P, Kurtzberg, J, and Sanz, G. "Nicord Single Unit Expanded Umbilical Cord Blood Transplantation (UCBT): Final Results of a Multicenter Phase I/II Trial." March 2018.

Scholars@Duke

Sivaraj, D, Bacon, W, Long, GD, Rizzieri, DA, Horwitz, ME, Sullivan, KM, Kang, Y, Li, Z, Chao, NJ, and Gasparetto, C. "High-dose BCNU/Melphalan conditioning regimen before autologous stem cell transplantation in newly diagnosed multiple myeloma." Bone marrow transplantation 53, no. 1 (January 2018): 34-38.

PMID
29084203
Full Text

Grant, MJ, and Horwitz, ME. "HSCT-GAVE as a Manifestation of Chronic Graft versus Host Disease: A Case Report and Review of the Existing Literature." Case Reports in Transplantation 2018 (January 2018): 2376483-null.

PMID
29721346
Full Text

Huang, L-W, Bacon, W, Cirrincione, C, Peterson, B, Long, G, Rizzieri, D, Sullivan, KM, Corbet, K, Horwitz, M, Chao, N, Gasparetto, C, and Tuchman, SA. "Efficacy and safety of high-dose chemotherapy with autologous stem cell transplantation in senior versus younger adults with newly diagnosed multiple myeloma." Hematological oncology 35, no. 4 (December 2017): 752-759.

PMID
28105753
Full Text

Pages