Hematologic Malignancies and Cellular Therapy

Mitchell Eric Horwitz, MD

Professor of Medicine
Member of the Duke Cancer Institute
Affiliate of the Regeneration Next Initiative
Campus mail 2400 Pratt St Suite 5000, DUMC Box 3961, Durham, NC 27710
Phone (919) 668-1000
Email address mitchell.horwitz@duke.edu

Allogeneic stem cell transplantation using umbilical cord blood grafts; Allogenic stem cell transplantation for Sickle Cell Disease; Prevention of acute graft versus host disease through donor stem cell graft manipulation; Improving immune recovery following alternative donor stem cell transplantation using donor graft manipulation or third party thymus transplantation.

In Their Words

Education and Training

  • Medical Resident, Medicine, Northwestern University, 1992 - 1995
  • M.D., Rush University, 1992

Grants

Publications

Maung, Ko K., Benny J. Chen, Ian Barak, Zhiguo Li, David A. Rizzieri, Cristina Gasparetto, Keith M. Sullivan, et al. “Phase I dose escalation study of naive T-cell depleted donor lymphocyte infusion following allogeneic stem cell transplantation.” Bone Marrow Transplantation 56, no. 1 (January 2021): 137–43. https://doi.org/10.1038/s41409-020-0991-5.

PMID
32624583
Full Text

Smith, Patrick, Jillian C. Thompson, Elena Perea, Brian Wasserman, Lauren Bohannon, Alessandro Racioppi, Taewoong Choi, et al. “Clinical and Neuroimaging Correlates of Post-Transplant Delirium.” Biol Blood Marrow Transplant 26, no. 12 (December 2020): 2323–28. https://doi.org/10.1016/j.bbmt.2020.09.016.

PMID
32961373
Full Text

Scaradavou, Andromachi, Scott T. Avecilla, Joann Tonon, Ioannis Politikos, Mitchell E. Horwitz, Joanne Kurtzberg, Filippo Milano, Juliet N. Barker, and Juliet N. American Society for Transplantation and Cellular Therapy Cord Blood Special Interest Group. “Guidelines for Cord Blood Unit Thaw and Infusion.” Biol Blood Marrow Transplant 26, no. 10 (October 2020): 1780–83. https://doi.org/10.1016/j.bbmt.2020.06.018.

PMID
32599214
Full Text

Foster, Gena G., Michael J. Grant, Samantha M. Thomas, Blake Cameron, Doug Raiff, Kelly Corbet, Gavin Loitsch, Christopher Ferreri, and Mitchell Horwitz. “Treatment with Foscarnet after Allogeneic Hematopoietic Cell Transplant (Allo-HCT) Is Associated with Long-Term Loss of Renal Function.” Biology of Blood and Marrow Transplantation : Journal of the American Society for Blood and Marrow Transplantation 26, no. 9 (September 2020): 1597–1606. https://doi.org/10.1016/j.bbmt.2020.05.007.

PMID
32450288
Full Text

Fuchs, Ephraim J., Paul V. O’Donnell, Mary Eapen, Brent R. Logan, Joseph H. Antin, Peter Dawson, Steven M. Devine, et al. “Double unrelated umbilical cord blood versus HLA-haploidentical bone marrow transplantation (BMT CTN 1101).” Blood, August 31, 2020. https://doi.org/10.1182/blood.2020007535.

PMID
32870242
Full Text

Saad, Ayman, Marcos de Lima, Sarah Anand, Vijaya Raj Bhatt, Ryan Bookout, George Chen, Daniel Couriel, et al. “Hematopoietic Cell Transplantation, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology.” J Natl Compr Canc Netw 18, no. 5 (May 1, 2020): 599–634. https://doi.org/10.6004/jnccn.2020.0021.

PMID
32519831
Full Text

Hourigan, Christopher S., Laura W. Dillon, Gege Gui, Brent R. Logan, Mingwei Fei, Jack Ghannam, Yuesheng Li, et al. “Impact of Conditioning Intensity of Allogeneic Transplantation for Acute Myeloid Leukemia With Genomic Evidence of Residual Disease.” J Clin Oncol 38, no. 12 (April 20, 2020): 1273–83. https://doi.org/10.1200/JCO.19.03011.

PMID
31860405
Full Text

Maung, Ko, Nelson Jen An Chao, Kelly Corbet, Ashley Morris Engemann, Cristina Gasparetto, Mitchell Horwitz, Yubin Kang, et al. “CLO20-049: Retrospective Study of Safety and Toxicity Profile Comparison for Propylene Glycol-Free Melphalan (Evomela®) and Generic Melphalan.” In Journal of the National Comprehensive Cancer Network, 18:CLO20-049. Harborside Press, LLC, 2020. https://doi.org/10.6004/jnccn.2019.7412.

Full Text

Smith, Patrick J., Meagan Lew, Yen P. Lowder, Kristi Romero, Jill Thompson, Lauren Bohannen, Alyssa Pittman, et al. “Cognitive Impairment in Candidates for Allogeneic Hematopoietic Stem Cell Transplantation.” In Biology of Blood and Marrow Transplantation, 26:S241–S241. ELSEVIER SCIENCE INC, 2020.

Scholars@Duke

Ramalingam, Sendhilnathan, Sharareh Siamakpour-Reihani, Lauren Bohannon, Yi Ren, Alexander Sibley, Andrew Nixon, Jing Lyu, et al. “Phase II Trial of Pasireotide to Prevent GI Toxicity and Acute Gvhd in Allogeneic HSCT.” In Biology of Blood and Marrow Transplantation, 26:S48–49. ELSEVIER SCIENCE INC, 2020.

Scholars@Duke

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