The focus of my research is disordered mineral metabolism across the spectrum of chronic kidney disease, including dialysis, kidney transplantation and earlier stages.
My research has been published in leading general medicine and subspecialty journals, including the New England Journal of Medicine, JAMA, the Journal of Clinical Investigation, Circulation, Cell Metabolism, Journal of the American Society of Nephrology, and Kidney International, among others.
My primary contributions have been in the area of hormonal regulation of phosphate homeostasis. I have helped to characterize the physiological role of fibroblast growth factor 23 in health and in chronic kidney disease, and the impact of elevated fibroblast growth factor 23 levels on adverse clinical outcomes in patients with kidney disease.
Education and Training
- Research Fellowship in Nephrology, Massachusetts General Hospital, 2000 - 2001
- Clinical Fellowship in Nephrology, Brigham and Women's Hospital, 1999 - 2000
- Internal Medicine Residency, Massachusetts General Hospital, 1996 - 1999
- M.Med.Sc., Harvard Medical School, 2002
- M.D., State University of New York at Brooklyn, 1996
- Duke CTSA (KL2)
- Duke CTSA (TL1)
- FGF23 and Cardiovascular Disease in CKD (CRIC)
- Role of FGF23 in Mineral Metabolism Across the Spectrum of Chronic Kidney Disease
- Pencast Videos to Boost Learning and Interest in Nephrology Among Internal Medicine Residents
- Molecular Mechanisms of Cardiac Injury Induced by FGF23 in the Settings of High Phosphate Diet and CKD
- Phosphate and FGF23: Dietary and Molecular Mediators of Health Disparities in Cardiovasular and Kidney Diseases (Center)
- Endocrinology and Metabolism Training Program
- Pilot Studies Targeting Mineral Metabolism in CKD
- Impact of phosphate and FGF23 reduction on intermediate end points in CKD