Nephrology

Myles Selig Wolf, MD

Professor of Medicine
Charles Johnson, M.D. Professor of Medicine
Chief of Nephrology
Professor in Population Health Sciences
Member of the Duke Clinical Research Institute
Email address myles.wolf@duke.edu
Fax: 919-684-3011

The focus of my research is disordered mineral metabolism across the spectrum of chronic kidney disease, including dialysis, kidney transplantation and earlier stages.

My research has been published in leading general medicine and subspecialty journals, including the New England Journal of Medicine, JAMA, the Journal of Clinical Investigation, Circulation, Cell Metabolism, Journal of the American Society of Nephrology, and Kidney International, among others.

My primary contributions have been in the area of hormonal regulation of phosphate homeostasis. I have helped to characterize the physiological role of fibroblast growth factor 23 in health and in chronic kidney disease, and the impact of elevated fibroblast growth factor 23 levels on adverse clinical outcomes in patients with kidney disease.

Education and Training

  • Research Fellowship in Nephrology, Massachusetts General Hospital, 2000 - 2001
  • Clinical Fellowship in Nephrology, Brigham and Women's Hospital, 1999 - 2000
  • Internal Medicine Residency, Massachusetts General Hospital, 1996 - 1999
  • M.Med.Sc., Harvard Medical School, 2002
  • M.D., State University of New York at Brooklyn, 1996

Grants

Publications

Amdur, RL, Feldman, HI, Dominic, EA, Anderson, AH, Beddhu, S, Rahman, M, Wolf, M, Reilly, M, Ojo, A, Townsend, RR, Go, AS, He, J, Xie, D, Thompson, S, Budoff, M, Kasner, S, Kimmel, PL, Kusek, JW, Raj, DS, and CRIC Study Investigators, . "Use of Measures of Inflammation and Kidney Function for Prediction of Atherosclerotic Vascular Disease Events and Death in Patients With CKD: Findings From the CRIC Study." American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation 73, no. 3 (March 2019): 344-353.

PMID
30545708
Full Text

Schrauben, SJ, Hsu, JY, Wright Nunes, J, Fischer, MJ, Srivastava, A, Chen, J, Charleston, J, Steigerwalt, S, Tan, TC, Fink, JC, Ricardo, AC, Lash, JP, Wolf, M, Feldman, HI, Anderson, AH, and CRIC Study Investigators, . "Health Behaviors in Younger and Older Adults With CKD: Results From the CRIC Study." Kidney International Reports 4, no. 1 (January 2019): 80-93.

PMID
30596171
Full Text

Robinson-Cohen, C, Perwad, F, Wolf, MS, De Boer, IH, Kestenbaum, B, Lipworth, L, Hung, A, and Ikizler, TA. "Genetic Variants Associated with Circulating Parathyroid Hormone among Patients with Chronic Kidney Disease." Annual Meeting of the American-Society-for-Bone-and-Mineral-Research. Montreal, CANADA. September 28, 2018 - October 1, 2018.: WILEY, November 1, 2018.

Scholars@Duke

Robinson-Cohen, C, Perwad, F, Wolf, MS, De Boer, IH, Kestenbaum, B, Lipworth, L, Hung, A, and Ikizler, TA. "Genetic Variants Associated with Circulating Parathyroid Hormone among Patients with Chronic Kidney Disease." Annual Meeting of the American-Society-for-Bone-and-Mineral-Research. Montreal, CANADA. September 28, 2018 - October 1, 2018.: WILEY, November 1, 2018.

Scholars@Duke

Prasad, PV, Li, W, Raj, DS, Carr, J, Carr, M, Thacker, J, Li, L-P, Wang, C, Sprague, SM, Ix, JH, Chonchol, M, Block, G, Cheung, AK, Raphael, K, Gassman, J, Wolf, M, Fried, LF, Isakova, T, and CKD Optimal Management with BInders and NicotinamidE (COMBINE) study group, . "Multicenter Study Evaluating Intrarenal Oxygenation and Fibrosis Using Magnetic Resonance Imaging in Individuals With Advanced CKD." Kidney International Reports 3, no. 6 (November 2018): 1467-1472. (Letter)

PMID
30450473
Full Text

Robinson-Cohen, C, Bartz, TM, Lai, D, Ikizler, TA, Peacock, M, Imel, EA, Michos, ED, Foroud, TM, Akesson, K, Taylor, KD, Malmgren, L, Matsushita, K, Nethander, M, Eriksson, J, Ohlsson, C, Mellström, D, Wolf, M, Ljunggren, O, McGuigan, F, Rotter, JI, Karlsson, M, Econs, MJ, Ix, JH, Lutsey, PL, Psaty, BM, de Boer, IH, and Kestenbaum, BR. "Genetic Variants Associated with Circulating Fibroblast Growth Factor 23." Journal of the American Society of Nephrology : Jasn 29, no. 10 (October 2018): 2583-2592.

PMID
30217807
Full Text

Scialla, JJ, Brown, L, Gurley, S, Corcoran, DL, Bain, JR, Muehlbauer, MJ, O'Neal, SK, M O'Connell, T, Wolf, M, Melamed, ML, Hostetter, TH, and Abramowitz, MK. "Metabolic Changes with Base-Loading in CKD." Clinical Journal of the American Society of Nephrology : Cjasn 13, no. 8 (August 2018): 1244-1246.

PMID
29934431
Full Text

Kolak, M, Bradley, M, Block, DR, Pool, L, Garg, G, Toman, CK, Boatright, K, Lipiszko, D, Koschinsky, J, Kershaw, K, Carnethon, M, Isakova, T, and Wolf, M. "Urban foodscape trends: Disparities in healthy food access in Chicago, 2007-2014." Health & Place 52 (July 9, 2018): 231-239.

PMID
30015180
Full Text

Neuburg, S, Dussold, C, Gerber, C, Wang, X, Francis, C, Qi, L, David, V, Wolf, M, and Martin, A. "Genetic background influences cardiac phenotype in murine chronic kidney disease." July 2018.

PMID
29309658
Full Text

Gerber, C, Cai, X, Lee, J, Craven, T, Scialla, J, Souma, N, Srivastava, A, Mehta, R, Paluch, A, Hodakowski, A, Frazier, R, Carnethon, MR, Wolf, MS, and Isakova, T. "Incidence and Progression of Chronic Kidney Disease in Black and White Individuals with Type 2 Diabetes." Clinical Journal of the American Society of Nephrology : Cjasn 13, no. 6 (June 2018): 884-892.

PMID
29798889
Full Text

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