Patricia Lynne Lugar, MD

Associate Professor of Medicine
Associate Professor in Pediatrics
Campus mail 1821 Hillandale Rd, Suite 25A, Durham, NC 27705
Phone (919) 613-5707
Email address patricia.lugar@duke.edu

I have a strong interest and research background in the study of dysregulated B lymphocytes, B cells, that characterize clinical disease such as autoimmune disease and humoral immune deficiency. My current research projects are aimed at the study of humoral immune deficiency, specifically common variable immune deficiency or CVID and the dysregulation of B cells in the generation of lymphoma and autoimmune disease.
Other ongoing research projects include characterizing the molecular and cellular events that cause a common disease, chronic idiopathic urticaria or CIU and rare disorders idiopathic anaphylaxis and idiopathic angioedema.

Education and Training

  • Fellowship in Allegy and Immunology, Niaid, National Institutes of Health, 2003 - 2006
  • Medical Resident, Medicine, Northwestern University, 1999 - 2002
  • M.D., State University of New York at Buffalo, 1999

Publications

Chinn, Ivan K., Alice Y. Chan, Karin Chen, Janet Chou, Morna J. Dorsey, Joud Hajjar, Artemio M. Jongco, et al. “Diagnostic interpretation of genetic studies in patients with primary immunodeficiency diseases: A working group report of the Primary Immunodeficiency Diseases Committee of the American Academy of Allergy, Asthma & Immunology.” J Allergy Clin Immunol 145, no. 1 (January 2020): 46–69. https://doi.org/10.1016/j.jaci.2019.09.009.

PMID
31568798
Full Text

Baloh, Carolyn, Anupama Reddy, Michele Henson, Katherine Prince, Rebecca Buckley, and Patricia Lugar. “30-Year Review of Pediatric- and Adult-Onset CVID: Clinical Correlates and Prognostic Indicators.” J Clin Immunol 39, no. 7 (October 2019): 678–87. https://doi.org/10.1007/s10875-019-00674-9.

PMID
31377970
Full Text

Kleris, Renee, Monica Tang, Cristine Radojicic, and Patricia L. Lugar. “Pricking away at penicillin allergy with a dedicated outpatient clinic.” J Allergy Clin Immunol Pract 7, no. 4 (April 2019): 1358-1359.e1. https://doi.org/10.1016/j.jaip.2018.10.023.

PMID
30967194
Full Text

Kleris, Renee S., and Patricia L. Lugar. “Things We Do For No Reason: Failing to Question a Penicillin Allergy History.” J Hosp Med 14, no. 10 (March 20, 2019): 704–6. https://doi.org/10.12788/jhm.3170.

PMID
30897049
Full Text

Baloh, Carolyn H., Michele R. Henson, Anupama Reddy, Rebecca H. Buckley, and Patricia L. Lugar. “A study of cancer incidence in the most common immunodeficiency, common variable immunodeficiency (CVID).” In Journal of Allergy and Clinical Immunology, 143:AB80–AB80. MOSBY-ELSEVIER, 2019.

Scholars@Duke

Gernez, Yael, Alexandra F. Freeman, Steven M. Holland, Elizabeth Garabedian, Niraj C. Patel, Jennifer M. Puck, Kathleen E. Sullivan, et al. “Autosomal Dominant Hyper-IgE Syndrome in the USIDNET Registry.” J Allergy Clin Immunol Pract 6, no. 3 (May 2018): 996–1001. https://doi.org/10.1016/j.jaip.2017.06.041.

PMID
28939137
Full Text

Lawrence, Monica G., Thamiris V. Palacios-Kibler, Lisa J. Workman, Alexander J. Schuyler, John W. Steinke, Spencer C. Payne, Emily C. McGowan, et al. “Low Serum IgE Is a Sensitive and Specific Marker for Common Variable Immunodeficiency (CVID).” J Clin Immunol 38, no. 3 (April 2018): 225–33. https://doi.org/10.1007/s10875-018-0476-0.

PMID
29453744
Full Text

Mayor, Paul C., Kevin H. Eng, Kelly L. Singel, Scott I. Abrams, Kunle Odunsi, Kirsten B. Moysich, Ramsay Fuleihan, et al. “Cancer in primary immunodeficiency diseases: Cancer incidence in the United States Immune Deficiency Network Registry.” J Allergy Clin Immunol 141, no. 3 (March 2018): 1028–35. https://doi.org/10.1016/j.jaci.2017.05.024.

PMID
28606585
Full Text

Baloh, Carolyn H., Anupama Reddy, Rebecca H. Buckley, and Patricia L. Lugar. “Characterization of pediatric onset common variable immunodeficiency (CVID) in a large cohort.” In Journal of Allergy and Clinical Immunology, 141:AB21–AB21. MOSBY-ELSEVIER, 2018.

Scholars@Duke

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